Research Topics
| I H BrownSummaryAffiliation: New Haw Country: UK Publications
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Detail Information
Publications
Antigenic and genetic analyses of H1N1 influenza A viruses from European pigsI H Brown
Central Veterinary Laboratory Weybridge, Addlestone, Surrey, UK
J Gen Virol 78:553-62. 1997..Genetic analyses of two recent 'avian-like' swine viruses indicated that all the RNA segments are related most closely to those of avian influenza A viruses...
Multiple genetic reassortment of avian and human influenza A viruses in European pigs, resulting in the emergence of an H1N2 virus of novel genotypeI H Brown
Central Veterinary Laboratory Weybridge, Addlestone, Surrey, UK
J Gen Virol 79:2947-55. 1998..These findings suggest multiple reassortment and replication of influenza viruses may occur in pigs many years before their detection as clinical entities...
The epidemiology and evolution of influenza viruses in pigsI H Brown
Veterinary Laboratories Agency Weybridge, New Haw, Addlestone, UK
Vet Microbiol 74:29-46. 2000..Both human H3N2 and avian H1N1 were detected in pigs many years before they acquired the ability to spread rapidly and become associated with disease epidemics in pigs...
Infection dynamics of highly pathogenic avian influenza and virulent avian paramyxovirus type 1 viruses in chickens, turkeys and ducksE W Aldous
Virology Department, Surrey, UK
Avian Pathol 39:265-73. 2010..6) EID(50)), but none died. In marked contrast, chickens were shown to be extremely susceptible to infection and all infected chickens died (ID(50)/LD(50)=10(1.9) EID(50))...
A molecular epidemiological investigation of avian paramyxovirus type 1 viruses isolated from game birds of the order GalliformesE W Aldous
Virology Department, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, UK
Avian Pathol 39:519-24. 2010....
Outbreak of Newcastle disease due to pigeon paramyxovirus type 1 in grey partridges (Perdix perdix) in Scotland in October 2006R M Irvine
Virology Department, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey KT15 3NB
Vet Rec 165:531-5. 2009..However, the virus could not be isolated from or detected in dead pigeons collected from the affected buildings...
Novel H1N1 influenza in people: global spread from an animal source?R M Irvine
Virology Department, Veterinary Laboratories Agency Weybridge, New Haw, Addlestone, Surrey KT15 3NB
Vet Rec 164:577-8. 2009..Richard Irvine and Ian Brown of the Veterinary Laboratories Agency discuss some epidemiological features of the novel H1N1 influenza virus that is currently causing concern among health authorities worldwide...
Surveillance for West Nile virus in British birds (2001 to 2006)L P Phipps
Veterinary Laboratories Agency - Weybridge, New Haw, Addlestone, Surrey KT15 3NB, UK
Vet Rec 162:413-5. 2008
Outbreak of Newcastle disease in pheasants (Phasianus colchicus) in south-east England in July 2005E W Aldous
Virology Department, Veterinary Laboratories Agency-Weybridge, New Haw, Addlestone, Surrey
Vet Rec 160:482-4. 2007
Pathogenicity of concurrent infection of pigs with porcine respiratory coronavirus and swine influenza virusI Lanza
Ministry of Agriculture, Fisheries and Food, Central Veterinary Laboratory, New Haw, Addlestone, Surrey
Res Vet Sci 53:309-14. 1992..Furthermore, viruses were isolated more frequently from tissues and nasal swabs taken from 'single' than 'dual' infected animals, suggesting a possible in vivo interference between replication of PRCV and swine influenza virus...
Advances in molecular diagnostics for avian influenzaI H Brown
Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, United Kingdom
Dev Biol (Basel) 124:93-7. 2006....
Experiences in control of avian influenza in Europe, the Russian Federation and the Middle EastI H Brown
Community Reference Laboratory for Avian Influenza, Veterinary Laboratories Agency, Weybridge, Addlestone, Surrey, UK
Dev Biol (Basel) 130:33-8. 2007..Application of such programmes would have to be preceded by an evaluation of the risks for introduction and spread and might be restricted...
Recent epidemiology and ecology of influenza A viruses in avian species in Europe and the Middle EastI H Brown
Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, United Kingdom
Dev Biol (Basel) 124:45-50. 2006....
Induced increase in virulence of low virulence highly [corrected] pathogenic avian influenza by serial intracerebral passage in chickensB Z Londt
Veterinary Laboratory Agency, Weybridge, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom
Avian Dis 51:396-400. 2007..These results further highlight that nucleotide changes in the genome other than at the HA cleavage site can attenuate the virulence of HPAI viruses...
Detection of West Nile virus in the tissues of specific pathogen free chickens and serological response to laboratory infection: a comparative studyL P Phipps
Virology Department, VLA Weybridge, Addlestone, Surrey, UK
Avian Pathol 36:301-5. 2007..It can be concluded that the PCR used in this study was more sensitive than virus isolation for the detection of WNV while the PRNT also appeared more sensitive than the conventional VN test...
First reported incursion of highly pathogenic notifiable avian influenza A H5N1 viruses from clade 2.3.2 into European poultryS M Reid
OIE, FAO, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, UK
Transbound Emerg Dis 58:76-8. 2011..3.2 viruses remains uncertain, ongoing vigilance for clinical signs of disease as part of existing passive surveillance frameworks for AI, and the prompt reporting of suspect cases in poultry is advised...
Genetic subtyping of influenza A viruses using RT-PCR with a single set of primers based on conserved sequences within the HA2 coding regionL P Phipps
Virology Department, Veterinary Laboratories Agency, New Haw, Addlestone, Surrey, UK
J Virol Methods 122:119-22. 2004..It is concluded that this RT-PCR is a reliable, robust and reproducible tool for the rapid identification of a wide range of all the HA subtypes of influenza A viruses...
Pathogenesis of H7 influenza A viruses isolated from ostriches in the homologous host infected experimentallyR J Manvell
Virology Department, Veterinary Laboratories Agency (Weybridge, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom
Avian Dis 47:1150-3. 2003..Postmortem examination of the birds infected (including the sentinel bird) with virus highly pathogenic for chickens were grossly normal except for localized pneumonic lesions. The results of the study are presented and discussed...
