K Woodward

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. pmc Pelizaeus-Merzbacher disease: identification of Xq22 proteolipid-protein duplications and characterization of breakpoints by interphase FISH
    K Woodward
    Molecular Genetics Unit, Institute of Child Health, Guy s Hosptial, London, United Kingdom
    Am J Hum Genet 63:207-17. 1998
  2. ncbi request reprint Proteolipid protein gene: Pelizaeus-Merzbacher disease in humans and neurodegeneration in mice
    K Woodward
    Molecular Genetics Unit, Institute of Child Health, 30 Guilford Street, London, UK WC1N 1EH
    Trends Genet 15:125-8. 1999
  3. ncbi request reprint Prenatal diagnosis by FISH in a family with Pelizaeus-Merzbacher disease caused by duplication of PLP gene
    K Woodward
    Molecular Genetics Unit, Institute of Child Health, University College London, UK
    Prenat Diagn 19:266-8. 1999
  4. ncbi request reprint X inactivation phenotype in carriers of Pelizaeus-Merzbacher disease: skewed in carriers of a duplication and random in carriers of point mutations
    K Woodward
    Molecular Genetics Unit, Institute of Child Health, London, UK
    Eur J Hum Genet 8:449-54. 2000
  5. ncbi request reprint CNS myelination and PLP gene dosage
    K Woodward
    Clinical Molecular Genetics Unit, Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
    Pharmacogenomics 2:263-72. 2001

Collaborators

Detail Information

Publications5

  1. pmc Pelizaeus-Merzbacher disease: identification of Xq22 proteolipid-protein duplications and characterization of breakpoints by interphase FISH
    K Woodward
    Molecular Genetics Unit, Institute of Child Health, Guy s Hosptial, London, United Kingdom
    Am J Hum Genet 63:207-17. 1998
    ..Since duplications are a major cause of PMD, we propose that interphase FISH is a reliable method for diagnosis and identification of female carriers...
  2. ncbi request reprint Proteolipid protein gene: Pelizaeus-Merzbacher disease in humans and neurodegeneration in mice
    K Woodward
    Molecular Genetics Unit, Institute of Child Health, 30 Guilford Street, London, UK WC1N 1EH
    Trends Genet 15:125-8. 1999
    ..Investigating the molecular basis of PMD in patients and animal models is furthering our understanding of the disease, dosage sensitivity and proteolipid protein function during myelinogenesis...
  3. ncbi request reprint Prenatal diagnosis by FISH in a family with Pelizaeus-Merzbacher disease caused by duplication of PLP gene
    K Woodward
    Molecular Genetics Unit, Institute of Child Health, University College London, UK
    Prenat Diagn 19:266-8. 1999
    ..The proband was found to carry the duplication, thus confirming the diagnosis of Pelizaeus Merzbacher disease, but neither the aunt nor the fetus carried a duplication...
  4. ncbi request reprint X inactivation phenotype in carriers of Pelizaeus-Merzbacher disease: skewed in carriers of a duplication and random in carriers of point mutations
    K Woodward
    Molecular Genetics Unit, Institute of Child Health, London, UK
    Eur J Hum Genet 8:449-54. 2000
    ....
  5. ncbi request reprint CNS myelination and PLP gene dosage
    K Woodward
    Clinical Molecular Genetics Unit, Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
    Pharmacogenomics 2:263-72. 2001
    ..Genome sequencing may identify intrinsic structural properties of the DNA with greater susceptibility to these rearrangements and thereby reflect structural changes in the genome...