J Wei

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi request reprint A study of the relationship between the DBH activity in serum and a MspI polymorphic site in intron 9 of the human DBH gene in schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, UK
    Schizophr Res 22:77-80. 1996
  2. ncbi request reprint Possible control of dopamine beta-hydroxylase via a codominant mechanism associated with the polymorphic (GT)n repeat at its gene locus in healthy individuals
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, Gwynedd, UK
    Hum Genet 99:52-5. 1997
  3. ncbi request reprint TaqI polymorphic sites at the human dopamine beta-hydroxylase gene possibly associated with biochemical alterations of the catecholamine pathway in schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, UK
    Psychiatr Genet 8:19-24. 1998
  4. ncbi request reprint The NOTCH4 locus is associated with susceptibility to schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bryn Hyfryd, The Crescent, Bangor, Gwynedd, UK
    Nat Genet 25:376-7. 2000
  5. ncbi request reprint TNXB locus may be a candidate gene predisposing to schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 125:43-9. 2004
  6. ncbi request reprint A study of linkage disequilibrium between polymorphic loci for monamine oxidases A and B in schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Society of Great Britain, Bangor, Gwynedd, UK
    Psychiatr Genet 9:177-81. 1999
  7. ncbi request reprint A study of a genetic association between the PTGS2/PLA2G4A locus and schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bryn Hyfryd, The Crescent Bangor, Gwynedd LL57 2AG, UK
    Prostaglandins Leukot Essent Fatty Acids 70:413-5. 2004
  8. ncbi request reprint Lack of evidence for association between the COMT locus and schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, Gwyndedd, UK
    Psychiatr Genet 9:183-6. 1999
  9. ncbi request reprint The CCK-A receptor gene possibly associated with auditory hallucinations in schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association Great Britain, Bryn Hyfryd, The Crescent, Bangor, Gwynedd LL57 2AG UK
    Eur Psychiatry 14:67-70. 1999
  10. ncbi request reprint Searching for a locus for schizophrenia within chromosome Xp11
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, U K
    Am J Med Genet 96:4-7. 2000

Collaborators

  • Y Wang
  • Y Shen
  • Y Q Yu
  • Y Yang
  • L Xie
  • Z Y Sun
  • J P Shi
  • Q Xu
  • X Zhang
  • G Z Ju
  • S Z Liu
  • F Miao
  • W Xie
  • C Shen
  • J Zhang
  • G P Hemmings
  • R Tao

Detail Information

Publications16

  1. ncbi request reprint A study of the relationship between the DBH activity in serum and a MspI polymorphic site in intron 9 of the human DBH gene in schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, UK
    Schizophr Res 22:77-80. 1996
    ..01). The present results suggest that the MspI polymorphic site in intron 9 of the human DBH gene may be associated with alterations of DBH activity in schizophrenia and with the influence of neuroleptic drugs on the DBH activity as well...
  2. ncbi request reprint Possible control of dopamine beta-hydroxylase via a codominant mechanism associated with the polymorphic (GT)n repeat at its gene locus in healthy individuals
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, Gwynedd, UK
    Hum Genet 99:52-5. 1997
    ..The present work suggests that the human DBH is likely to be controlled via a codominant mechanism associated with the dinucleotide repeat polymorphism at its gene locus...
  3. ncbi request reprint TaqI polymorphic sites at the human dopamine beta-hydroxylase gene possibly associated with biochemical alterations of the catecholamine pathway in schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, UK
    Psychiatr Genet 8:19-24. 1998
    ....
  4. ncbi request reprint The NOTCH4 locus is associated with susceptibility to schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bryn Hyfryd, The Crescent, Bangor, Gwynedd, UK
    Nat Genet 25:376-7. 2000
    ..The A-->G substitution in the promoter region and the (CTG)n repeat in exon 1 of NOTCH4 may be candidate sites conferring susceptibility to schizophrenia...
  5. ncbi request reprint TNXB locus may be a candidate gene predisposing to schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 125:43-9. 2004
    ..The haplotype analysis suggested that there might be more than one disease-related allele located in the class III region of the MHC, and that these alleles possibly confer either susceptibility or resistance to schizophrenia...
  6. ncbi request reprint A study of linkage disequilibrium between polymorphic loci for monamine oxidases A and B in schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Society of Great Britain, Bangor, Gwynedd, UK
    Psychiatr Genet 9:177-81. 1999
    ....
  7. ncbi request reprint A study of a genetic association between the PTGS2/PLA2G4A locus and schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bryn Hyfryd, The Crescent Bangor, Gwynedd LL57 2AG, UK
    Prostaglandins Leukot Essent Fatty Acids 70:413-5. 2004
    ..Because these two genes are arranged in a head-to-head configuration and separated by just about 149kb of DNA, they may have a combined effect on susceptibility to schizophrenia in some cases...
  8. ncbi request reprint Lack of evidence for association between the COMT locus and schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, Gwyndedd, UK
    Psychiatr Genet 9:183-6. 1999
    ..Nevertheless, there may be a susceptibility gene for schizophrenia in a distinct region from the COMT locus on chromosome 22q, as a genome scan has suggested recently...
  9. ncbi request reprint The CCK-A receptor gene possibly associated with auditory hallucinations in schizophrenia
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association Great Britain, Bryn Hyfryd, The Crescent, Bangor, Gwynedd LL57 2AG UK
    Eur Psychiatry 14:67-70. 1999
    ..54, df = 1,P = 0.033) but not in those of schizophrenic patients without them. The present study suggests that the CCK-A receptor gene may be associated with auditory hallucinations in schizophrenia...
  10. ncbi request reprint Searching for a locus for schizophrenia within chromosome Xp11
    J Wei
    Institute of Biological Psychiatry, Schizophrenia Association of Great Britain, Bangor, U K
    Am J Med Genet 96:4-7. 2000
    ..It is possible that one of these genes or some loci near to it may predispose a vulnerability to schizophrenia. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:4-7, 2000...
  11. ncbi request reprint Gene, gut and schizophrenia: the meeting point for the gene-environment interaction in developing schizophrenia
    J Wei
    Schizophrenia Association of Great Britain, Institute of Biological Psychiatry, Bryn Hyfryd, The Crescent, Bangor LL57 2AG, UK
    Med Hypotheses 64:547-52. 2005
    ..The results demonstrate that these two genes possibly work together in conferring a susceptibility to schizophrenia...
  12. ncbi request reprint The CLDN5 locus may be involved in the vulnerability to schizophrenia
    Z Y Sun
    Jilin University Research Center for Genomic Medicine, School of Public Health, Jilin University, Changchun 130021, China
    Eur Psychiatry 19:354-7. 2004
    ....
  13. ncbi request reprint No association between the PTGS2/PLA2G4A locus and schizophrenia in a Chinese population
    Y Q Yu
    Jilin University Research Center for Genomic Medicine, School of Public Health, Jilin University, Changchun 130021, China
    Prostaglandins Leukot Essent Fatty Acids 71:405-8. 2004
    ....
  14. ncbi request reprint Characterization of murine Girk2 transcript isoforms: structure and differential expression
    J Wei
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, 46202 5251, USA
    Genomics 51:379-90. 1998
    ..An additional transcript, Girk2D, appears to be brain-specific, not polyadenylated, and highly expressed in cerebellar granule cells...
  15. ncbi request reprint Linkage mapping of microdissected clones from distal mouse chromosome 16
    J Wei
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202 5251, USA
    Somat Cell Mol Genet 22:227-32. 1996
    ..This map on distal mouse chromosome 16 should be a useful tool for the mouse genome project and for studies of genes in the region...
  16. doi request reprint Loss of heterozygosity at 6p21 underlying [corrected] HLA class I downregulation in Chinese primary esophageal squamous cell carcinomas
    Y Yang
    Key Laboratory of Developmental Genes and Human Disease of Education Ministry, Department of Genetics and Developmental Biology, Southeast University Medical School, Nanjing, Jiangsu, China
    Tissue Antigens 72:105-14. 2008
    ..3 is a frequent mechanism that leads to HLA class I abnormalities in pESCC...