Ryohei Sekido

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi request reprint SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors
    Ryohei Sekido
    Division of Developmental Genetics, MRC National Institute for Medical Research, London NW7 1AA, UK
    Dev Biol 274:271-9. 2004
  2. pmc Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination
    Yuna Kim
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA
    PLoS Biol 4:e187. 2006
  3. ncbi request reprint Mechanisms of gonadal morphogenesis are not conserved between chick and mouse
    Ryohei Sekido
    Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London, UK
    Dev Biol 302:132-42. 2007
  4. ncbi request reprint The origin of the Mullerian duct in chick and mouse
    Silvana Guioli
    Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Dev Biol 302:389-98. 2007
  5. doi request reprint Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer
    Ryohei Sekido
    Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Nature 453:930-4. 2008
  6. doi request reprint Genetic control of testis development
    R Sekido
    Division of Stem Cell Biology and Developmental Genetics, MRC National Institute for Medical Research, London NW7 AA, UK
    Sex Dev 7:21-32. 2013
  7. doi request reprint SRY: A transcriptional activator of mammalian testis determination
    Ryohei Sekido
    Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 AA, UK
    Int J Biochem Cell Biol 42:417-20. 2010
  8. doi request reprint Sex determination and SRY: down to a wink and a nudge?
    Ryohei Sekido
    Division of Developmental Genetics, Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Trends Genet 25:19-29. 2009
  9. ncbi request reprint Sex-determining genes in mice: building pathways
    Robin Lovell-Badge
    Division of Developmental Genetics, MRC National Institute for Medical Research, London, UK
    Novartis Found Symp 244:4-18; discussion 18-22, 35-42, 253-7. 2002
  10. pmc Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination
    Yuna Kim
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 104:16558-63. 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors
    Ryohei Sekido
    Division of Developmental Genetics, MRC National Institute for Medical Research, London NW7 1AA, UK
    Dev Biol 274:271-9. 2004
    ....
  2. pmc Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination
    Yuna Kim
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA
    PLoS Biol 4:e187. 2006
    ..In principle, sex determination in other vertebrates may operate through any switch that introduces an imbalance between these two signaling pathways...
  3. ncbi request reprint Mechanisms of gonadal morphogenesis are not conserved between chick and mouse
    Ryohei Sekido
    Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London, UK
    Dev Biol 302:132-42. 2007
    ....
  4. ncbi request reprint The origin of the Mullerian duct in chick and mouse
    Silvana Guioli
    Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Dev Biol 302:389-98. 2007
    ..Our data provide clues of the underlying mechanism of tubulogenesis relevant to both normal and abnormal development of the female reproductive tract...
  5. doi request reprint Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer
    Ryohei Sekido
    Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Nature 453:930-4. 2008
    ..Our results open up the field, permitting further characterization of the molecular mechanisms regulating sex determination and how they have evolved, as well as how they fail in cases of sex reversal...
  6. doi request reprint Genetic control of testis development
    R Sekido
    Division of Stem Cell Biology and Developmental Genetics, MRC National Institute for Medical Research, London NW7 AA, UK
    Sex Dev 7:21-32. 2013
    ..In this review, we summarize our current understanding of genetic pathways of testis determination and differentiation in mammals, particularly in the mouse and the human...
  7. doi request reprint SRY: A transcriptional activator of mammalian testis determination
    Ryohei Sekido
    Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 AA, UK
    Int J Biochem Cell Biol 42:417-20. 2010
    ..Furthermore, this SRY action is limited to a certain time period during embryogenesis...
  8. doi request reprint Sex determination and SRY: down to a wink and a nudge?
    Ryohei Sekido
    Division of Developmental Genetics, Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Trends Genet 25:19-29. 2009
    ..We also explore the common features between sex determination in mammals and in other vertebrates that lack Sry...
  9. ncbi request reprint Sex-determining genes in mice: building pathways
    Robin Lovell-Badge
    Division of Developmental Genetics, MRC National Institute for Medical Research, London, UK
    Novartis Found Symp 244:4-18; discussion 18-22, 35-42, 253-7. 2002
    ..Progress in establishing other regulatory interactions will also be discussed...
  10. pmc Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination
    Yuna Kim
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 104:16558-63. 2007
    ..Using these two Cre lines, we provide the first genetic evidence that Fgfr2 plays distinct roles in proliferation and Sertoli cell differentiation during testis development...