Mahesh Kb Parmar

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi Speeding up the evaluation of new agents in cancer
    Mahesh K B Parmar
    Clinical Trials Unit, London, UK
    J Natl Cancer Inst 100:1204-14. 2008
  2. ncbi Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit
    Patrick Royston
    MRC Clinical Trials, London NW1 2DA UK
    Trials 12:81. 2011
  3. ncbi How do multi-stage, multi-arm trials compare to the traditional two-arm parallel group design--a reanalysis of 4 trials
    F M S Barthel
    Department of Biostatistics, Institute of Psychiatry, King s College London, London, UK
    Trials 10:21. 2009
  4. ncbi Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial
    Matthew R Sydes
    MRC Clinical Trials Unit, London, UK
    Trials 10:39. 2009

Collaborators

  • Michael A Bookman
  • Patrick Royston
  • Matthew R Sydes
  • F M S Barthel
  • Babak Choodari-Oskooei
  • Valerie Isham
  • Friederike M S Barthel
  • Noel W Clarke
  • P Royston
  • Rachel C Morgan
  • Nicholas D James
  • Karen Sanders
  • Malcolm D Mason
  • David P Dearnaley

Detail Information

Publications4

  1. ncbi Speeding up the evaluation of new agents in cancer
    Mahesh K B Parmar
    Clinical Trials Unit, London, UK
    J Natl Cancer Inst 100:1204-14. 2008
    ..By using intermediate outcomes and testing a number of new agents (and combinations) simultaneously, the new design requires fewer patients. Three trials using this methodology are presented...
  2. ncbi Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit
    Patrick Royston
    MRC Clinical Trials, London NW1 2DA UK
    Trials 12:81. 2011
    ..Such trials can terminate at any of the intermediate stages or the final stage...
  3. ncbi How do multi-stage, multi-arm trials compare to the traditional two-arm parallel group design--a reanalysis of 4 trials
    F M S Barthel
    Department of Biostatistics, Institute of Psychiatry, King s College London, London, UK
    Trials 10:21. 2009
    ..To speed up the evaluation of new therapies, the multi-arm, multi-stage trial design was suggested previously by the authors...
  4. ncbi Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial
    Matthew R Sydes
    MRC Clinical Trials Unit, London, UK
    Trials 10:39. 2009
    ..The MAMS design will potentially facilitate evaluation and testing of new therapies in this and other diseases...