Research Topics
Genomes and GenesSpecies | Elke A OberSummaryAffiliation: National Institute for Medical Research Country: UK Publications
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Detail Information
Publications
Large-scale mapping of mutations affecting zebrafish developmentRobert Geisler
Department 3 Genetics, Max Planck Institut fur Entwicklungsbiologie, Spemannstr, 35 III, 72076 Tubingen, Germany
BMC Genomics 8:11. 2007..Here we report on a large-scale effort to map the mutations generated in mutagenesis screening at the Max Planck Institute for Developmental Biology by genome scanning with microsatellite markers...
Mesodermal Wnt2b signalling positively regulates liver specificationElke A Ober
Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, and the Liver Center, University of California, San Francisco, 1550 Fourth Street, San Francisco, California 94143, USA
Nature 442:688-91. 2006..Taken together, these data reveal an unexpected positive role for Wnt signalling in liver specification, and indicate a possible common theme for the localized formation of endodermal organs along the gut tube...- Multiple roles for Med12 in vertebrate endoderm developmentChong Hyun Shin
Department of Biochemistry and Biophysics, Liver Center, University of California, San Francisco, CA 94158, USA
Dev Biol 317:467-79. 2008.... - Bmp and Fgf signaling are essential for liver specification in zebrafishDonghun Shin
Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, Liver Center, University of California, San Francisco, CA 94158, USA
Development 134:2041-50. 2007.... - Genetic and cellular analyses of zebrafish atrioventricular cushion and valve developmentDimitris Beis
Department of Biochemistry and Biophysics and Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA
Development 132:4193-204. 2005..This collection of mutants provides a unique set of tools to further our understanding of the genetic basis of cell behavior and differentiation during AV valve development... - The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafishNick Osborne
Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, Cardiovascular Research Institute, University of California, San Francisco, 1550 Fourth Street, San Francisco, CA 94143, USA
Curr Biol 18:1882-8. 2008..Through gain- and loss-of-function analyses, we show that toh is required for signaling by S1P(2). Further evidence indicates that Toh is involved in the trafficking or cellular release of S1P... - A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryosSuk Won Jin
Department of Biochemistry and Biophysics, Genetics and Human Genetics, and Cardiovascular Research Institute, University of California San Francisco, CA 94158, USA
Dev Biol 307:29-42. 2007..The analysis of the newly defined loci should lead to a greater understanding of vascular development and possibly provide new drug targets to treat the numerous pathologies associated with dysregulated blood vessel growth... - The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration modelSilvia Curado
Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, University of California San Francisco, 1550 Fourth Street, San Francisco, CA 94158 2324, USA
Dis Model Mech 3:486-95. 2010..We used this regeneration model to analyze the signaling commonalities between hepatocyte development and regeneration... - Vegfc is required for vascular development and endoderm morphogenesis in zebrafishElke A Ober
Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, University of California, San Francisco, California 94143 0448, USA
EMBO Rep 5:78-84. 2004.... - Regulation of neurocoel morphogenesis by Pard6 gamma bChantilly Munson
Department of Biochemistry and Biophysics, Genetics and Human Genetics, University of California, San Francisco, CA 94158, USA
Dev Biol 324:41-54. 2008..Altogether, these data indicate a previously unappreciated functional diversity and complexity within the vertebrate pard6 gene family... - Formation of the digestive system in zebrafish. I. Liver morphogenesisHolly A Field
Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, University of California, San Francisco, San Francisco, CA 94143, USA
Dev Biol 253:279-90. 2003.... - From endoderm formation to liver and pancreas development in zebrafishElke A Ober
Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, University of California, San Francisco, CA 94143-0448, USA
Mech Dev 120:5-18. 2003..The generation of transgenic lines expressing GFP in these organs promises to be particularly helpful in such studies... - Loss of eyes in zebrafish caused by mutation of chokh/rx3Felix Loosli
Developmental Biology Programme, European Molecular Biology Laboratory, Meyerhofstrasse 1, PO Box 10 2209, 69012 Heidelberg, Germany
EMBO Rep 4:894-9. 2003..Thus, these mutations in orthologous genes allow us to study the evolution of vertebrate eye development at the molecular level...