Michael F Murphy

Summary

Affiliation: National Blood Service
Country: UK

Publications

  1. ncbi request reprint Platelet transfusion in neonatal alloimmune thrombocytopenia
    David Allen
    Blood 109:388-9. 2007
  2. ncbi request reprint Current performance of patient sample collection in the UK
    M F Murphy
    National Blood Service, John Radcliffe Hospital, Headington, Oxford OX3 9BQ, UK
    Transfus Med 14:113-21. 2004
  3. ncbi request reprint Prevention of bedside errors in transfusion medicine (PROBE-TM) study: a cluster-randomized, matched-paired clinical areas trial of a simple intervention to reduce errors in the pretransfusion bedside check
    Michael F Murphy
    National Blood Service, John Radcliffe Hospital, Oxford, UK
    Transfusion 47:771-80. 2007
  4. ncbi request reprint Survey of the implementation of the recommendations in the Health Service Circular 2002/009 'Better Blood Transfusion'
    M F Murphy
    National Blood Service, Oxford, UK
    Transfus Med 15:453-60. 2005
  5. ncbi request reprint Strategies for reducing the exposure to donor blood
    Mike Murphy
    National Blood Service, Department of Haematology, Oxford Radcliffe Hospitals, University of Oxford
    Clin Med 5:337-40. 2005
  6. ncbi request reprint Surveillance of transfusion errors: putting data to use in the U.K
    M F Murphy
    National Blood Service, Department of Haematology, John Radcliffe Hospital, Oxford, and the University of Oxford, UK
    Dev Biol (Basel) 120:179-87. 2005
  7. ncbi request reprint Barcode identification for transfusion safety
    M F Murphy
    National Blood Service, John Radcliffe Hospital, Oxford, UK
    Curr Opin Hematol 11:334-8. 2004
  8. ncbi request reprint Patient identification: problems and potential solutions
    M F Murphy
    National Blood Service, Oxford Radcliffe Hospital, UK
    Vox Sang 87:197-202. 2004
  9. ncbi request reprint Advances in the management of alloimmune thrombocytopenia
    Michael F Murphy
    National Blood Service, Department of Haematology, John Radcliffe Hospital, University of Oxford, Oxford, UK
    Br J Haematol 136:366-78. 2007
  10. ncbi request reprint National audit of the blood transfusion process in the UK
    M F Murphy
    National Blood Service, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Transfus Med 11:363-70. 2001

Collaborators

Detail Information

Publications52

  1. ncbi request reprint Platelet transfusion in neonatal alloimmune thrombocytopenia
    David Allen
    Blood 109:388-9. 2007
  2. ncbi request reprint Current performance of patient sample collection in the UK
    M F Murphy
    National Blood Service, John Radcliffe Hospital, Headington, Oxford OX3 9BQ, UK
    Transfus Med 14:113-21. 2004
    ..Regular tracking of the rates of sample rejection and WBIT could be used to identify poor performance in individual hospitals requiring investigation and action...
  3. ncbi request reprint Prevention of bedside errors in transfusion medicine (PROBE-TM) study: a cluster-randomized, matched-paired clinical areas trial of a simple intervention to reduce errors in the pretransfusion bedside check
    Michael F Murphy
    National Blood Service, John Radcliffe Hospital, Oxford, UK
    Transfusion 47:771-80. 2007
    ..The intervention was a tag on blood bags reminding staff to check the patient's wristband. The tag was positioned in such a way that the transfusionist was required to remove the tag to spike the unit...
  4. ncbi request reprint Survey of the implementation of the recommendations in the Health Service Circular 2002/009 'Better Blood Transfusion'
    M F Murphy
    National Blood Service, Oxford, UK
    Transfus Med 15:453-60. 2005
    ..This information should be used to plan further local, regional and national initiatives to implement the Better Blood Transfusion action plan and improve transfusion practice...
  5. ncbi request reprint Strategies for reducing the exposure to donor blood
    Mike Murphy
    National Blood Service, Department of Haematology, Oxford Radcliffe Hospitals, University of Oxford
    Clin Med 5:337-40. 2005
  6. ncbi request reprint Surveillance of transfusion errors: putting data to use in the U.K
    M F Murphy
    National Blood Service, Department of Haematology, John Radcliffe Hospital, Oxford, and the University of Oxford, UK
    Dev Biol (Basel) 120:179-87. 2005
    ....
  7. ncbi request reprint Barcode identification for transfusion safety
    M F Murphy
    National Blood Service, John Radcliffe Hospital, Oxford, UK
    Curr Opin Hematol 11:334-8. 2004
    ..Errors related to blood transfusion in hospitals may produce catastrophic consequences. This review addresses potential solutions to prevent patient misidentification including the use of new technology, such as barcoding...
  8. ncbi request reprint Patient identification: problems and potential solutions
    M F Murphy
    National Blood Service, Oxford Radcliffe Hospital, UK
    Vox Sang 87:197-202. 2004
  9. ncbi request reprint Advances in the management of alloimmune thrombocytopenia
    Michael F Murphy
    National Blood Service, Department of Haematology, John Radcliffe Hospital, University of Oxford, Oxford, UK
    Br J Haematol 136:366-78. 2007
    ..However, the ideal antenatal treatment, which is effective without causing significant side-effects to the mother or fetus, has yet to be determined, and further clinical trials are needed...
  10. ncbi request reprint National audit of the blood transfusion process in the UK
    M F Murphy
    National Blood Service, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Transfus Med 11:363-70. 2001
    ..The type of analysis and the method used for the presentation of audit data developed in this study may be useful for setting performance indicators for the clinical transfusion process...
  11. ncbi request reprint Survey of the implementation of the recommendations in the Health Services Circular 1998/224 'Better Blood Transfusion'
    M F Murphy
    National Blood Service, Oxford Radcliffe Hospitals, and University of Oxford, Oxford, UK
    Transfus Med 13:121-5. 2003
    ..New initiatives including the issue of a further HSC on 'Better Blood Transfusion' are aimed at enabling hospitals to improve their transfusion practice in a more systematic way than that was found in the results of this survey...
  12. ncbi request reprint Antenatal screening for fetomaternal alloimmune thrombocytopenia: should we be doing it?
    M F Murphy
    National Blood Service, Department of Haematology, John Radcliffe Hospital, and University of Oxford
    Vox Sang 83:409-16. 2002
  13. ncbi request reprint Application of bar code technology at the bedside: the Oxford experience
    Michael F Murphy
    National Blood Service and John Radcliffe Hospital, Oxford, UK
    Transfusion 47:120S-124S; discussion 130S-131S. 2007
  14. doi request reprint Antifibrinolytics (lysine analogues) for the prevention of bleeding in patients with haematological disorders
    Douglas Wardrop
    Oxford Cancer and Haematology Centre, Haematology, Oxford, UK
    Cochrane Database Syst Rev 7:CD009733. 2013
    ..PlTx are not without risk and adverse events may be life-threatening. A possible adjunct to prophylactic PlTxs is the use of antifibrinolytics, specifically the lysine analogues tranexamic acid (TXA) and epsilon aminocaproic acid (EACA)...
  15. doi request reprint What is the maximum time that a unit of red blood cells can be safely left out of controlled temperature storage?
    Susan Brunskill
    NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK, OX3 9BQ
    Transfus Med Rev 26:209-223.e3. 2012
    ....
  16. ncbi request reprint The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions
    Lise J Estcourt
    NHS Blood and Transplant Oxford University Hospitals NHS Trust, NIHR Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
    Transfusion 53:1531-43. 2013
    ..Differences in the way bleeding has been identified, recorded, and graded may account for some of this variability. This study's aim was to compare trials' method to document and grade bleeding...
  17. doi request reprint A no-prophylaxis platelet-transfusion strategy for hematologic cancers
    Simon J Stanworth
    National Health Service NHS Blood and Transplant, Oxford University Hospitals NHS Trust, John Radcliffe Hospital, and Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
    N Engl J Med 368:1771-80. 2013
    ..This trial assessed whether a policy of not giving prophylactic platelet transfusions was as effective and safe as a policy of providing prophylaxis...
  18. ncbi request reprint Electronic remote blood issue: a combination of remote blood issue with a system for end-to-end electronic control of transfusion to provide a "total solution" for a safe and timely hospital blood transfusion service
    Julie Staves
    Oxford Radcliffe Hospitals, National Blood Service, Oxford, UK
    Transfusion 48:415-24. 2008
    ..A further development is the issue of blood under electronic control at blood refrigerator remote from the blood bank...
  19. doi request reprint Evaluation of the Impact-R for monitoring the platelet storage lesion
    Abdul Majeed Albanyan
    Oxford Haemophilia and Thrombosis Centre, Churchill Hospital, Oxford, UK
    Platelets 20:1-6. 2009
    ..The Impact-R is a simple device to perform rapid test which may be useful for the assessment of platelet function within platelet concentrates...
  20. doi request reprint Measurement of phosphatidylserine exposure during storage of platelet concentrates using the novel probe lactadherin: a comparison study with annexin V
    Abdul Majeed Albanyan
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Transfusion 49:99-107. 2009
    ..The aim of this study was to compare annexin V and lactadherin labeling of PLTs in PLT concentrates (PCs)...
  21. ncbi request reprint Prospective observational cohort study of the association between thromboelastometry, coagulation and platelet parameters and bleeding in patients with haematological malignancies- The ATHENA study
    Lise J Estcourt
    NHS Blood and Transplant, Oxford, UK Radcliffe Department of Medicine, University of Oxford, Oxford, UK
    Br J Haematol 166:581-91. 2014
    ..In a predictive model, AIPN was superior to TPC for predicting bleeding. This study indicates that AIPN may be more clinically useful than TPC at predicting bleeding. ..
  22. doi request reprint Factors affecting red blood cell storage age at the time of transfusion
    Walter H Dzik
    Massachusetts General Hospital, Boston, Massachusetts Filton Blood Centre, Bristol, UK John Radcliffe Hospital, National Blood Service, Oxford, UK University of Washington, Seattle, Washington New Zealand Blood Service, Auckland, New Zealand Fletcher Allen Health Care, Burlington, Vermont Hema Quebec, Ste Foy, Quebec, Canada Beth Israel Deaconess Medical Center, Boston, Massachusetts Hospital Clinic Provincial, Barcelona, Spain Hoxworth Blood Center, Cincinnati, Ohio Sírio Libanês Hospital, Sao Paulo, Brazil Dartmouth Hitchcock Medical Center, Lebanon, NH
    Transfusion 53:3110-9. 2013
    ..Although progressive reduction in the maximum storage period of RBCs would be expected to result in smaller hospital inventories and reduced blood availability, the magnitude of the effect is unknown...
  23. doi request reprint Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after chemotherapy and stem cell transplantation
    Lise Estcourt
    Haematology Transfusion Medicine, NHS Blood and Transplant, Oxford, UK
    Cochrane Database Syst Rev 5:CD004269. 2012
    ....
  24. doi request reprint Prophylactic platelet transfusions
    Lise J Estcourt
    Haematology Transfusion Medicine, NHS Blood and Transplant and the NIHR Biomedical Research Centre, Oxford, UK
    Curr Opin Hematol 17:411-7. 2010
    ..This review highlights the recent research on the use of prophylactic platelet transfusions, which is a topic that still provokes controversy. Over the last 12 months, there have been several studies with important new findings...
  25. ncbi request reprint End-to-end electronic control of the hospital transfusion process to increase the safety of blood transfusion: strengths and weaknesses
    Amanda Davies
    National Blood Service, Oxford Radcliffe Hospitals, Oxford, UK
    Transfusion 46:352-64. 2006
    ..Incorrect blood component transfused is a frequent serious incident associated with transfusion and often involves misidentification of the patient and/or the unit of blood...
  26. doi request reprint National comparative audit of the use of platelet transfusions in the UK
    H Qureshi
    National Blood Service, John Radcliffe Hospital, Headley Way, Headington, Oxford, United Kingdom
    Transfus Clin Biol 14:509-13. 2007
    ....
  27. doi request reprint Evidence for indications of fresh frozen plasma
    S J Stanworth
    National Blood Service, John Radcliffe Hospital, Osler Road, Headington, Oxford, United Kingdom
    Transfus Clin Biol 14:551-6. 2007
    ..In addition, new haemostatic tests should be validated which better define risk of bleeding...
  28. ncbi request reprint A systematic review of randomized controlled trials for plasma exchange in the treatment of thrombotic thrombocytopenic purpura
    S J Brunskill
    National Blood Service, John Radcliffe Hospital, Headley Way, Oxford, UK
    Transfus Med 17:17-35. 2007
    ..Continued support of existing TTP patient registries and establishment of new registries would facilitate this...
  29. doi request reprint Improving the evidence base for transfusion medicine: the work of the UK systematic review initiative
    S J Brunskill
    NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK
    Transfus Med 19:59-65. 2009
    ..Collaboration between international and local research groups is important if these challenges are to be met...
  30. ncbi request reprint Feasibility and usefulness of self-assessment of bleeding in patients with haematological malignancies, and the association between platelet count and bleeding
    S J Stanworth
    Department of Haematology, John Radcliffe Hospital, Headington, Oxford, UK
    Vox Sang 91:63-9. 2006
    ..The aim of this study was to evaluate the collection of daily prospective information about bleeding outcomes in patients with thrombocytopenia, including information obtained by patient self-assessment...
  31. ncbi request reprint Platelet transfusion prophylaxis for patients with haematological malignancies: where to now?
    S J Stanworth
    National Blood Service, John Radcliffe Hospital, Headington, Oxford, UK
    Br J Haematol 131:588-95. 2005
    ....
  32. ncbi request reprint Survey of the use of whole blood in current blood transfusion practice
    S Maclennan
    National Blood Service Transfusion Medicine Clinical Policies Group, National Blood Service, Leeds, UK
    Clin Lab Haematol 23:391-6. 2001
    ..It is worth noting that, as currently supplied in the UK, "whole blood" is not strictly "whole" as the leucocyte-depletion process removes platelets...
  33. ncbi request reprint Leucocyte-depleted blood in prevention of post-operative infections following elective orthopaedic and cardiac procedures
    L M Williamson
    National Blood Service, and University of Cambridge
    Vox Sang 83:457-60. 2002
  34. ncbi request reprint Survey of the use and clinical effectiveness of HPA-1a/5b-negative platelet concentrates in proven or suspected platelet alloimmunization
    D L Allen
    National Blood Service, John Radcliffe Hospital, Headington, Oxford OX3 9BQ, UK
    Transfus Med 14:409-17. 2004
    ..Increased use and cost-effectiveness could be achieved by the delivery of an educational programme to neonatal unit clinical staff to increase the awareness and appropriate treatment of NAIT...
  35. ncbi request reprint Is fresh frozen plasma clinically effective? A systematic review of randomized controlled trials
    S J Stanworth
    NBS, Level 2, John Radcliffe Hospital, Headington, Oxford, UK
    Br J Haematol 126:139-52. 2004
    ..Trials of modified FFP (e.g. pathogen inactivated) are of questionable value when there is little evidence that the standard product is an effective treatment...
  36. pmc Restrictive vs liberal blood transfusion for acute upper gastrointestinal bleeding: rationale and protocol for a cluster randomized feasibility trial
    Vipul Jairath
    NHS Blood and Transplant, Oxford, United Kingdom
    Transfus Med Rev 27:146-53. 2013
    ..The results of this study will inform the feasibility and design of a phase III randomized trial. ..
  37. doi request reprint Prevalence, management, and outcomes of patients with coagulopathy after acute nonvariceal upper gastrointestinal bleeding in the United Kingdom
    Vipul Jairath
    NHS Blood and Transplant and the Translational Gastroenterology Unit, Oxford University Hospitals, Oxford, UK
    Transfusion 53:1069-76. 2013
    ..We describe the prevalence, use of plasma, and outcomes of patients with coagulopathy after acute nonvariceal upper gastrointestinal bleeding (NVUGIB)...
  38. doi request reprint Human platelet antigen 1a epitopes are dependent on the cation-regulated conformation of integrin α(IIb)β(3) (GPIIb/IIIa)
    David L Allen
    NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK
    J Immunol Methods 375:166-75. 2012
    ....
  39. doi request reprint Markers of platelet activation and apoptosis during storage of apheresis- and buffy coat-derived platelet concentrates for 7 days
    Abdul Majeed Albanyan
    Nuffield Department of Clinical Medicine, University of Oxford, National, Oxford, UK
    Transfusion 49:108-17. 2009
    ..The aim of this study was to compare in vitro variables of PCs produced by apheresis (AP-PC) or the buffy coat (BC-PC) method by applying a number of new and established assays...
  40. ncbi request reprint European collaborative study of the antenatal management of feto-maternal alloimmune thrombocytopenia
    Janet E Birchall
    National Blood Service, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 122:275-88. 2003
    ..The results of this study suggest that the start of therapy can be stratified on the basis of the sibling history of FMAIT, and support the use of maternal therapy as first-line treatment...
  41. doi request reprint The incidence and outcomes of fetomaternal alloimmune thrombocytopenia: a UK national study using three data sources
    Marian Knight
    National Perinatal Epidemiology Unit, University of Oxford, Oxford NHS Blood and Transplant Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Oxford, UK
    Br J Haematol 152:460-8. 2011
    ..There were a number of cases in which the significance of a history of FMAIT in a previous sibling was not recognized and there is a need to raise awareness of the importance of this diagnosis...
  42. ncbi request reprint Reducing blood use: how we did it
    Michael F Murphy
    National Blood Service and John Radcliffe Hospital, Oxford, UK
    Transfusion 47:149S-151S; discussion 155S-156S. 2007
  43. ncbi request reprint Review: platelet alloantigens and antibodies and their clinical significance
    A Norton
    Department of Hematology, National Blood Service, Oxford OX3 9BQ, UK
    Immunohematology 20:89-102. 2004
  44. ncbi request reprint Appraisal of the evidence for the clinical use of FFP and plasma fractions
    S J Stanworth
    National Blood Service, John Radcliffe Hospital, Headington, Oxford OX3 9BQ, UK
    Best Pract Res Clin Haematol 19:67-82. 2006
    ..Although the SAFE trial showed no increase in mortality with albumin compared with saline, it is difficult to justify its use in critical care given its considerably greater cost...
  45. pmc Neonatal alloimmune thrombocytopenia
    R Rayment
    National Blood Service, John Radcliffe Hospital, Oxford OX3 9DU
    BMJ 327:331-2. 2003
  46. ncbi request reprint Barcode technology: its role in increasing the safety of blood transfusion
    C L Turner
    National Blood Service, Oxford, UK
    Transfusion 43:1200-9. 2003
    ..Incorrect blood component transfusion is the most frequent serious incident associated with transfusion. Errors responsible for these incidents frequently involve patient misidentification...
  47. ncbi request reprint Accuracy of platelet counting haematology analysers in severe thrombocytopenia and potential impact on platelet transfusion
    H C Segal
    National Blood Service, Oxford, UK
    Br J Haematol 128:520-5. 2005
    ..It re-emphasizes the need for external quality control to improve analyser calibration for samples with low platelet counts, and suggests that the optimal thresholds for prophylactic platelet transfusions should be re-evaluated...
  48. ncbi request reprint High incidence of defective high-shear platelet function among platelet donors
    Paul Harrison
    Oxford Haemophilia Center and Thrombosis Unit, Churchill Hospital, Headington, Oxford, UK
    Transfusion 44:764-70. 2004
    ..There has been little previous work on PLT function in blood donors...
  49. doi request reprint Towards better blood transfusion--recruitment and training
    Q A Hill
    Department of Haematology, St James s Institute of Oncology, St James s University Hospital, Leeds, UK
    Transfus Med 19:2-5. 2009
    ..Improved research opportunities, joint NHSBT/hospital posts and a separate subspecialty training curriculum may stimulate interest in transfusion medicine...
  50. ncbi request reprint Immunoplatelet counting: potential for reducing the use of platelet transfusions through more accurate platelet counting
    Scott Norris
    Haematology Department, Oxford Radcliffe NHS Trust, Oxford, UK
    Br J Haematol 121:605-13. 2003
    ..4% in comparison with the same threshold using the Bayer H3 analyser. The immunoplatelet count may aid the clinical decision to transfuse platelets, but would not necessarily lead to a reduced use of platelet transfusions...
  51. pmc Childhood cancer incidence in a cohort of twin babies
    M F Murphy
    Imperial Cancer Research Fund, General Practice Research Group, Institute of Health Sciences, Old Road, Headington, Oxford, OX3 7LF, UK
    Br J Cancer 84:1460-2. 2001
    ..Pooled analysis with data from published cohort studies indicates a similar significant incidence reduction (SIR 81, 95% CI 67-96). Further studies are warranted...
  52. pmc Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States
    D C Whiteman
    ICRF General Practice Research Group, University of Oxford, Oxford, UK
    Br J Cancer 83:1231-3. 2000
    ..16 expected based on national rates (standardized rate ratio 0.68, 95% confidence interval 0.34-1.22) and conclude that any adverse influence of in utero oestrogen exposure is likely to be small...