David R Moore

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi request reprint Auditory processing disorder (APD)-potential contribution of mouse research
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Brain Res 1091:200-6. 2006
  2. ncbi request reprint Auditory processing disorders: acquisition and treatment
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    J Commun Disord 40:295-304. 2007
  3. doi request reprint Development of auditory processing in 6- to 11-yr-old children
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham, United Kingdom
    Ear Hear 32:269-85. 2011
  4. doi request reprint Stroke recovery and sensory plasticity: common mechanisms?
    David R Moore
    MRC Institute of Hearing Research, Nottingham NG7 2RD, UK
    Dev Psychobiol 54:326-31. 2012
  5. ncbi request reprint Discrimination training of phonemic contrasts enhances phonological processing in mainstream school children
    David R Moore
    MindWeavers Ltd, Oxford Centre for Innovation, Mill Street, Oxford OX2 0JX, UK
    Brain Lang 94:72-85. 2005
  6. doi request reprint The diagnosis and management of auditory processing disorder
    David R Moore
    Medical Research Council Institute of Hearing Research, Nottingham, UK
    Lang Speech Hear Serv Sch 42:303-8. 2011
  7. doi request reprint Nature of auditory processing disorder in children
    David R Moore
    Medical Research Council Institute of Hearing Research, Nottingham, UK
    Pediatrics 126:e382-90. 2010
  8. ncbi request reprint Effects of otitis media with effusion (OME) on central auditory function
    David R Moore
    University Laboratory of Physiology, University of Oxford, Parks Road, Oxford OX1 3PT, UK
    Int J Pediatr Otorhinolaryngol 67:S63-7. 2003
  9. doi request reprint Frequency discrimination in children: perception, learning and attention
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Hear Res 238:147-54. 2008
  10. pmc The descending corticocollicular pathway mediates learning-induced auditory plasticity
    Victoria M Bajo
    Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
    Nat Neurosci 13:253-60. 2010

Detail Information

Publications55

  1. ncbi request reprint Auditory processing disorder (APD)-potential contribution of mouse research
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Brain Res 1091:200-6. 2006
    ..For secondary assessment, standard psychoacoustic tests for mice have been developed...
  2. ncbi request reprint Auditory processing disorders: acquisition and treatment
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    J Commun Disord 40:295-304. 2007
    ..4) Readers will be able to explain what auditory learning is, list some of its properties, and provide examples of its application in therapy for communication disorders...
  3. doi request reprint Development of auditory processing in 6- to 11-yr-old children
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham, United Kingdom
    Ear Hear 32:269-85. 2011
    ..This study also informs choices on the selection of tests for clinical evaluation of hearing and listening (e.g., for auditory processing disorder)...
  4. doi request reprint Stroke recovery and sensory plasticity: common mechanisms?
    David R Moore
    MRC Institute of Hearing Research, Nottingham NG7 2RD, UK
    Dev Psychobiol 54:326-31. 2012
    ..The observed amplification from one brain region to another of degeneration following stroke or discrete brain lesions may thus be due to secondary rather than primary afferent consequences of the lesion...
  5. ncbi request reprint Discrimination training of phonemic contrasts enhances phonological processing in mainstream school children
    David R Moore
    MindWeavers Ltd, Oxford Centre for Innovation, Mill Street, Oxford OX2 0JX, UK
    Brain Lang 94:72-85. 2005
    ..Enhancements on the trained discriminations were weak and variable. The results indicate a dramatic improvement in phonological awareness following phonemic discrimination training without matching perceptual learning...
  6. doi request reprint The diagnosis and management of auditory processing disorder
    David R Moore
    Medical Research Council Institute of Hearing Research, Nottingham, UK
    Lang Speech Hear Serv Sch 42:303-8. 2011
    ..To provide a personal perspective on auditory processing disorder (APD), with reference to the recent clinical forum on APD and the needs of clinical speech-language pathologists and audiologists...
  7. doi request reprint Nature of auditory processing disorder in children
    David R Moore
    Medical Research Council Institute of Hearing Research, Nottingham, UK
    Pediatrics 126:e382-90. 2010
    ..We tested the specific hypothesis that the presentation of auditory processing disorder (APD) is related to a sensory processing deficit...
  8. ncbi request reprint Effects of otitis media with effusion (OME) on central auditory function
    David R Moore
    University Laboratory of Physiology, University of Oxford, Parks Road, Oxford OX1 3PT, UK
    Int J Pediatr Otorhinolaryngol 67:S63-7. 2003
    ..However, given time (6-24 months) and training, all animals regained normal temporal resolution...
  9. doi request reprint Frequency discrimination in children: perception, learning and attention
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Hear Res 238:147-54. 2008
    ....
  10. pmc The descending corticocollicular pathway mediates learning-induced auditory plasticity
    Victoria M Bajo
    Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
    Nat Neurosci 13:253-60. 2010
    ..The integrity of this descending pathway is therefore critical for learning-induced localization plasticity...
  11. pmc Lesions of the auditory cortex impair azimuthal sound localization and its recalibration in ferrets
    Fernando R Nodal
    Dept of Physiology, Anatomy and Genetics, Sherrington Bldg, Univ of Oxford, Parks Rd, Oxford OX1 3PT, UK
    J Neurophysiol 103:1209-25. 2010
    ..They also show that the auditory cortex, and A1 in particular, plays an essential role in training-induced plasticity in adult ferrets, and that this is the case for both head orienting responses and approach-to-target behavior...
  12. doi request reprint Reduction of internal noise in auditory perceptual learning
    Pete R Jones
    MRC Insitute of Hearing Research, University Park, Nottingham NG7 2RD, United Kingdom
    J Acoust Soc Am 133:970-81. 2013
    ..These results also indicated that auditory learning represents internal noise reduction, potentially through the re-weighting of frequency-specific channels...
  13. doi request reprint Training speech-in-noise perception in mainstream school children
    Kerri E Millward
    MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, United Kingdom
    Int J Pediatr Otorhinolaryngol 75:1408-17. 2011
    ..The aim of this experiment was to assess if sentence-in-noise perception could be improved using simpler auditory training stimuli...
  14. doi request reprint Evolving concepts of developmental auditory processing disorder (APD): a British Society of Audiology APD special interest group 'white paper'
    David R Moore
    MRC Institute of Hearing Research, Nottingham, UK
    Int J Audiol 52:3-13. 2013
    ..This approach has proved successful for LI, and may in future serve as a metric to help assess other, objective testing methods...
  15. doi request reprint Frequency discrimination learning in children
    Lorna F Halliday
    MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, United Kingdom
    J Acoust Soc Am 123:4393-402. 2008
    ..The results indicate that it is possible for some children to achieve FD thresholds comparable to those of naive adults, either natively or after limited training...
  16. doi request reprint Listening difficulties in children: bottom-up and top-down contributions
    David R Moore
    MRC Institute of Hearing Research, Nottingham NG7 2RD, UK
    J Commun Disord 45:411-8. 2012
    ..In some children, impaired top-down function presents a significant challenge to their auditory perception, often associated with a range of language and learning difficulties and sometimes called auditory processing disorder...
  17. pmc Olivocochlear efferent control in sound localization and experience-dependent learning
    Samuel Irving
    Medical Research Council Institute of Hearing Research, Nottingham NG7 2RD, United Kingdom
    J Neurosci 31:2493-501. 2011
    ..Lesions in all reported cases were verified histologically. The results suggest the OC system is not needed for accurate localization, but that it is involved in relearning localization during unilateral conductive hearing loss...
  18. ncbi request reprint The auditory basis of language impairments: temporal processing versus processing efficiency hypotheses
    Douglas E H Hartley
    University Laboratory of Physiology, University of Parks Roads, Oxford OX1 3PT, UK
    Int J Pediatr Otorhinolaryngol 67:S137-42. 2003
    ..These findings provide a new perspective on the mechanisms underlying communication disorders, and imply that remediation strategies should be directed towards improving processing efficiency, not temporal resolution...
  19. ncbi request reprint Auditory processing efficiency and temporal resolution in children and adults
    Penelope R Hill
    University Laboratory of Physiology, Oxford University, Oxford, United Kingdom
    J Speech Lang Hear Res 47:1022-9. 2004
    ..Therefore, the differences in BM threshold between adults and children were not due to differences in temporal resolution but to reduced detection efficiency in the children...
  20. doi request reprint Communication, listening, cognitive and speech perception skills in children with auditory processing disorder (APD) or Specific Language Impairment (SLI)
    Melanie A Ferguson
    Medical Research Council Institute of Hearing Research Clinical Section, Nottingham, United Kingdom
    J Speech Lang Hear Res 54:211-27. 2011
    ..The primary aim was to identify whether there were differences between these characteristics in children with SLI or APD...
  21. ncbi request reprint Lack of generalization of auditory learning in typically developing children
    Lorna F Halliday
    MRC Institute of Hearing Research, University Park, Nottingham, UK
    J Speech Lang Hear Res 55:168-81. 2012
    ..To understand the components of auditory learning in typically developing children by assessing generalization across stimuli, across modalities (i.e., hearing, vision), and to higher level language tasks...
  22. ncbi request reprint Auditory processing efficiency deficits in children with developmental language impairments
    Douglas E H Hartley
    University Laboratory of Physiology, University of Oxford, Parks Road, Oxford OX1 3PT, United Kingdom
    J Acoust Soc Am 112:2962-6. 2002
    ..These findings provide a new perspective on the mechanisms underlying communication disorders and auditory masking...
  23. doi request reprint Training sound localization in normal hearing listeners with and without a unilateral ear plug
    Samuel Irving
    University Park, MRC Institute of Hearing Research, Nottingham NG7 2RD, United Kingdom
    Hear Res 280:100-8. 2011
    ..The return to preplug learning performance suggests that the original location map is preserved despite the formation of a new map, and is in agreement with other reported findings...
  24. ncbi request reprint Discrimination learning induced by training with identical stimuli
    Sygal Amitay
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Nat Neurosci 9:1446-8. 2006
    ..We suggest that three processes are necessary for optimal perceptual learning: sensitization through exposure to the stimulus, modality- and dimension-specific attention, and general arousal...
  25. ncbi request reprint A comparison of adaptive procedures for rapid and reliable threshold assessment and training in naive listeners
    Sygal Amitay
    MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, United Kingdom
    J Acoust Soc Am 119:1616-25. 2006
    ..In four additional groups, each of ten listeners, trained on the different procedures, no differences in performance improvement or rate of learning were observed, suggesting that learning is independent of procedure...
  26. pmc Use of auditory learning to manage listening problems in children
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Philos Trans R Soc Lond B Biol Sci 364:409-20. 2009
    ..Promotion of retention and transfer of learning are major goals for further research...
  27. pmc A new test of attention in listening (TAIL) predicts auditory performance
    Yu Xuan Zhang
    Medical Research Council, Institute of Hearing Research, Nottingham, United Kingdom
    PLoS ONE 7:e53502. 2012
    ..The TAIL thus has the power to identify and separate contributions of different components of attention to auditory perception...
  28. pmc Dimension-specific attention directs learning and listening on auditory training tasks
    Lorna F Halliday
    MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, UK
    Atten Percept Psychophys 73:1329-35. 2011
    ..These findings suggest that top-down, dimension-specific attention can direct auditory learning, even when this learning is not reflected in conventional performance measures of threshold change...
  29. pmc Motivation and intelligence drive auditory perceptual learning
    Sygal Amitay
    Medical Research Council Institute of Hearing Research, Nottingham, United Kingdom
    PLoS ONE 5:e9816. 2010
    ..We investigated the effect of providing varying amounts of positive feedback while listeners attempted to discriminate between three identical tones on learning frequency discrimination...
  30. doi request reprint Planar localisation analyses: a novel application of a centre of mass approach
    A Mark Edmondson-Jones
    MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, UK
    Hear Res 267:4-11. 2010
    ..This spatial method offers powerful, yet flexible, statistical analysis using standard multivariate analysis of variance (MANOVA)...
  31. ncbi request reprint Effects of conductive hearing loss on temporal aspects of sound transmission through the ear
    Douglas E H Hartley
    University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK
    Hear Res 177:53-60. 2003
    ..In normal animals, CM responses were not delayed over a wide range of stimulus levels. Therefore, in addition to attenuation, conductive loss distorts acoustic temporal cues important for hearing...
  32. ncbi request reprint Early and rapid perceptual learning
    David J C Hawkey
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Nat Neurosci 7:1055-6. 2004
    ....
  33. ncbi request reprint Effects of otitis media with effusion on auditory temporal resolution
    Douglas E H Hartley
    University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK
    Int J Pediatr Otorhinolaryngol 69:757-69. 2005
    ..This study investigated the residual effects of OME on auditory temporal resolution. EXPERIMENT 1:..
  34. pmc Human decision making based on variations in internal noise: an EEG study
    Sygal Amitay
    Medical Research Council Institute of Hearing Research, Nottingham, United Kingdom
    PLoS ONE 8:e68928. 2013
    ..Our results suggest that activity variations induced by internal noise of both sensory and cognitive origin are sufficient to drive discrimination judgments. ..
  35. pmc Less is more: latent learning is maximized by shorter training sessions in auditory perceptual learning
    Katharine Molloy
    Medical Research Council Institute of Hearing Research, Nottingham, United Kingdom
    PLoS ONE 7:e36929. 2012
    ....
  36. doi request reprint Beyond cochlear implants: awakening the deafened brain
    David R Moore
    Medical Research Council, Institute of Hearing Research, Nottingham, UK
    Nat Neurosci 12:686-91. 2009
    ..We discuss recent evidence suggesting that developing the ability of the brain to learn how to use an implant may be as important as further improvements of the implant technology...
  37. ncbi request reprint Descending projections from the auditory cortex to the inferior colliculus in the gerbil, Meriones unguiculatus
    Victoria M Bajo
    University Laboratory of Physiology, University of Oxford, Oxford OX1 3PT, United Kingdom
    J Comp Neurol 486:101-16. 2005
    ..Descending connections to the gerbil IC form a segregated system in which multiple descending channels originating from different neuronal subpopulations may modulate specific aspects of ascending auditory information...
  38. doi request reprint Prevalence of clinical referrals having hearing thresholds within normal limits
    Sally E Hind
    Medical Research Council Institute of Hearing Research, Nottingham, UK
    Int J Audiol 50:708-16. 2011
    ..To document the prevalence of clinically normal air conduction thresholds (0.5-4 kHz, bilaterally, ≤20 dB HL) among children and adults in a large audiology service and to estimate the prevalence of auditory processing disorder (APD)...
  39. pmc Impaired binaural hearing in children produced by a threshold level of middle ear disease
    Sarah C M Hogan
    University Laboratory of Physiology, University of Oxford, Oxford OX1 3PT, United Kingdom
    J Assoc Res Otolaryngol 4:123-9. 2003
    ....
  40. doi request reprint Processes that influence communicative impairments in deaf children using cochlear implants
    Jayne Ramirez-Inscoe
    1Nottingham Cochlear Implant Programme, Ropewalk House, Nottingham, United Kingdom
    Ear Hear 32:690-8. 2011
    ..We also investigated laterality as a possible coindicator of impairment among the CI users...
  41. ncbi request reprint The ferret auditory cortex: descending projections to the inferior colliculus
    Victoria M Bajo
    Department of Physiology, Anatomy and Genetics, Sherrington Building, University of Oxford, Parks Road, Oxford OX1 3PT, UK
    Cereb Cortex 17:475-91. 2007
    ..This pattern of corticocollicular connectivity is consistent with regional differences in physiological properties and provides another basis for subdividing ferret auditory cortex into functionally distinct areas...
  42. ncbi request reprint Auditory frequency discrimination learning is affected by stimulus variability
    Sygal Amitay
    MRC Institute of Hearing Research, Nottingham, England
    Percept Psychophys 67:691-8. 2005
    ..Thus, the effects of training set on progress and outcome depend on set variability and individual FD ability...
  43. ncbi request reprint Perceptual learning: top to bottom
    Sygal Amitay
    Medical Research Council Institute of Hearing Research, University Park, Nottingham NG7 2RD, United Kingdom Electronic address
    Vision Res 99:69-77. 2014
    ....
  44. doi request reprint Learning to detect a tone in unpredictable noise
    Pete R Jones
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, United Kingdom
    J Acoust Soc Am 135:EL128-33. 2014
    ..Once changes in weights were accounted for, no changes in internal noise (psychometric slope) were observed. It is concluded that this task elicits robust learning, which can be understood primarily as improved selective attention. ..
  45. ncbi request reprint Auditory perceptual learning
    David R Moore
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Learn Mem 10:83-5. 2003
  46. ncbi request reprint Auditory development and the role of experience
    David R Moore
    University Laboratory of Physiology, Oxford, UK
    Br Med Bull 63:171-81. 2002
    ..This environmental influence may either be harmful, as during conductive deafness, or beneficial, as evidenced by the positive outcomes of auditory training...
  47. ncbi request reprint Ultrastructural transynaptic effects of unilateral cochlear ablation in the gerbil medial superior olive
    F Anne Russell
    University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK
    Hear Res 173:43-61. 2002
    ..These changes are likely to affect the probability of transmitter release and thus influence their signaling power within the nucleus...
  48. ncbi request reprint Assessment of children with suspected auditory processing disorder: a factor analysis study
    Ansar U Ahmmed
    1Lancashire Teaching Hospital NHS Foundation Trust, Preston, United Kingdom 2University of Newcastle, United Kingdom 3NIHR National Biomedical Research, Nottingham, United Kingdom 4University of Manchester, United Kingdom 5MRC Institute of Hearing Research, Nottingham, United Kingdom 6Cincinnati Children s Hospital, Cincinnati, Ohio, USA
    Ear Hear 35:295-305. 2014
    ..This would facilitate greater understanding of the nature of listening difficulties, thus further helping with characterizing APD and designing multimodal test batteries to diagnose APD...
  49. pmc Benefits of phoneme discrimination training in a randomized controlled trial of 50- to 74-year-olds with mild hearing loss
    Melanie A Ferguson
    1National Institute for Health Research Nottingham Hearing Biomedical Research Unit, Nottingham, United Kingdom 2Medical Research Council Institute of Hearing Research, Nottingham, United Kingdom and 3Cincinnati Children s Hospital, Cincinnati, Ohio, USA
    Ear Hear 35:e110-21. 2014
    ....
  50. ncbi request reprint Auditory neuroscience: the salience of looming sounds
    Deborah A Hall
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK
    Curr Biol 13:R91-3. 2003
    ..Recent studies in human and non-human primates have demonstrated a perceptual and behavioural priority for such looming sounds that is also reflected in an asymmetric pattern of cortical activation...
  51. ncbi request reprint Functional asymmetry for auditory processing in human primary auditory cortex
    Joseph T Devlin
    Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    J Neurosci 23:11516-22. 2003
    ....
  52. ncbi request reprint Cortical neurons signal sound novelty
    David R Moore
    Nat Neurosci 6:330-2. 2003
  53. doi request reprint The auditory brain--a tribute to Dexter R.F. Irvine
    David R Moore
    Hear Res 238:1-2. 2008
  54. doi request reprint The need for a cool head: reversible inactivation reveals functional segregation in auditory cortex
    Christian J Sumner
    Nat Neurosci 11:530-1. 2008
  55. ncbi request reprint Disproportionate language impairment in children using cochlear implants
    Kelvin Hawker
    Nottingham Cochlear Implant Programme, Ropewalk House, Nottingham, NG1 6HA
    Ear Hear 29:467-71. 2008
    ..To examine the nature of previously unexplained, severe language impairments in some children using a cochlear implant (CI)...