Philip D Minor

Summary

Affiliation: National Institute for Biological Standards and Control
Country: UK

Publications

  1. ncbi request reprint Emerging/disappearing viruses future issues concerning polio eradication
    P Minor
    NIBSC, Division of Virology, Potters Bar, Hertfordshire, UK
    Virus Res 82:33-7. 2002
  2. ncbi request reprint Virological issues in the use of cell therapies
    P D Minor
    NIBSC, Potters Bar, Herts, UK
    Dev Biol (Basel) 118:151-3. 2004
  3. ncbi request reprint Production cell substrates and vCJD
    R D Minor
    National Institute for Biological Standards and Control, Potters Bar, Herts, UK
    Dev Biol (Basel) 123:325-33; discussion 349-54. 2006
  4. ncbi request reprint Gaps in scientific knowledge for the post eradication world
    Philip Minor
    National Institute for Biological Standards and Control NIBSC, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
    Biologicals 34:167-70. 2006
  5. pmc Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes
    Ronald Dijkman
    Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Virol J 3:106. 2006
  6. ncbi request reprint Are recombinant products really infection risk free?
    P D Minor
    National Institute for Biological Standards and Control, Potters Bar Hertfordshire, UK
    Haemophilia 7:114-6. 2001
  7. ncbi request reprint Transgenic animals for the production of biological medicines
    P D Minor
    NIBSC, Potters Bar, Herts, UK
    Dev Biol (Basel) 118:165-9. 2004
  8. ncbi request reprint Effect of different immunisation schedules on the excretion and reversion of oral poliovaccine strains
    P D Minor
    National Institute for Biological Standards and Control, Blanche Lane South Mimms, Potters Bar, Herts, EN6 3QG, UK
    J Med Virol 75:153-60. 2005
  9. ncbi request reprint Standards for the assay of Creutzfeldt-Jakob disease specimens
    P Minor
    NIBSC, Blanche Lane, South Mimms, Potters Bar EN6 3QG, UK
    J Gen Virol 85:1777-84. 2004
  10. ncbi request reprint Polio eradication, cessation of vaccination and re-emergence of disease
    Philip D Minor
    National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3PG, UK
    Nat Rev Microbiol 2:473-82. 2004

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Emerging/disappearing viruses future issues concerning polio eradication
    P Minor
    NIBSC, Division of Virology, Potters Bar, Hertfordshire, UK
    Virus Res 82:33-7. 2002
  2. ncbi request reprint Virological issues in the use of cell therapies
    P D Minor
    NIBSC, Potters Bar, Herts, UK
    Dev Biol (Basel) 118:151-3. 2004
    ....
  3. ncbi request reprint Production cell substrates and vCJD
    R D Minor
    National Institute for Biological Standards and Control, Potters Bar, Herts, UK
    Dev Biol (Basel) 123:325-33; discussion 349-54. 2006
  4. ncbi request reprint Gaps in scientific knowledge for the post eradication world
    Philip Minor
    National Institute for Biological Standards and Control NIBSC, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
    Biologicals 34:167-70. 2006
    ....
  5. pmc Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes
    Ronald Dijkman
    Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Virol J 3:106. 2006
    ....
  6. ncbi request reprint Are recombinant products really infection risk free?
    P D Minor
    National Institute for Biological Standards and Control, Potters Bar Hertfordshire, UK
    Haemophilia 7:114-6. 2001
    ..Validated production processes make a major contribution to product safety however...
  7. ncbi request reprint Transgenic animals for the production of biological medicines
    P D Minor
    NIBSC, Potters Bar, Herts, UK
    Dev Biol (Basel) 118:165-9. 2004
  8. ncbi request reprint Effect of different immunisation schedules on the excretion and reversion of oral poliovaccine strains
    P D Minor
    National Institute for Biological Standards and Control, Blanche Lane South Mimms, Potters Bar, Herts, EN6 3QG, UK
    J Med Virol 75:153-60. 2005
    ..The data are consistent with the view that poliovirus is able to escape the immune pressure in the gut to some extent by improving its general fitness rather than direct evasion of immunity...
  9. ncbi request reprint Standards for the assay of Creutzfeldt-Jakob disease specimens
    P Minor
    NIBSC, Blanche Lane, South Mimms, Potters Bar EN6 3QG, UK
    J Gen Virol 85:1777-84. 2004
    ..The materials have been given the status of reference reagents by the World Health Organization and are available for further study and assessment of other in vitro or in vivo assay procedures...
  10. ncbi request reprint Polio eradication, cessation of vaccination and re-emergence of disease
    Philip D Minor
    National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3PG, UK
    Nat Rev Microbiol 2:473-82. 2004
  11. ncbi request reprint Technical aspects of the development and validation of tests for variant Creutzfeldt-Jakob disease in blood transfusion
    P D Minor
    NIBSC, Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, UK
    Vox Sang 86:164-70. 2004
    ..A rapid infectivity assay is key to confirming positives in human samples, and dilutions of infected human brain will probably provide adequate routine control samples to ensure the correct performance of the test...
  12. ncbi request reprint The challenge for the public health system
    Philip D Minor
    National Institute for Biological Standards and Control, South Mimms, Potters Bar, UK
    Contrib Microbiol 11:208-15. 2004
  13. doi request reprint Current challenges in implementing cell-derived influenza vaccines: implications for production and regulation, July 2007, NIBSC, Potters Bar, UK
    Philip D Minor
    National Institute for Biological Standards and Control, South Mimms, Potters Bar, Herts, UK
    Vaccine 27:2907-13. 2009
    ..Future studies to progress the field were reviewed...
  14. ncbi request reprint Antibodies to SV40 in sera from humans and macaques
    P Minor
    National Institute for Biological Standards and Control, Potters Bar, UK
    Dev Biol (Basel) 123:99-107; discussion 119-32. 2006
  15. ncbi request reprint Polio vaccines and the cessation of vaccination
    Philip D Minor
    Division of Virology, NIBSC, Potters Bar, Herts, UK
    Expert Rev Vaccines 2:99-104. 2003
    ..Some of the difficulties that this implies for the eventual complete cessation of vaccination are proving to be real not theoretical...
  16. pmc Changes in population dynamics during long-term evolution of sabin type 1 poliovirus in an immunodeficient patient
    John K Odoom
    Division of Virology, National Institute for Biological Standards and Control, Blanche Lane, Potters Bar, Hertfordshire EN63QG, United Kingdom
    J Virol 82:9179-90. 2008
    ..The relevance of vaccine-derived poliovirus strains for disease surveillance and future polio immunization policies is discussed in the context of the Global Polio Eradication Initiative...
  17. pmc Long-term excretion of vaccine-derived poliovirus by a healthy child
    Javier Martin
    Division of Virology, National Institute for Biological Standards and Control, Blanche Lane, Potters Bar, Hertfordshire EN6 3QG, United Kingdom
    J Virol 78:13839-47. 2004
    ..This anomaly could explain the high VP1 sequence drift found and the ability of these virus strains to replicate in the gut for a longer period than expected...
  18. ncbi request reprint Characterization of formaldehyde-inactivated poliovirus preparations made from live-attenuated strains
    Javier Martin
    Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire EN6 3QG, UK
    J Gen Virol 84:1781-8. 2003
    ..A novel transgenic mouse model to study in vivo the immune protection induced by IPV preparations is described...
  19. pmc Isolation of an intertypic poliovirus capsid recombinant from a child with vaccine-associated paralytic poliomyelitis
    Javier Martin
    Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, United Kingdom
    J Virol 76:10921-8. 2002
    ....
  20. doi request reprint Development of working reference materials for clinical virology
    Jacqueline F Fryer
    National Institute for Biological Standards and Control, Hertfordshire EN6 3QG, UK
    J Clin Virol 43:367-71. 2008
    ..Preliminary results presented here indicate a high level of variability in intra- and inter-assay detection of these targets, highlighting the need for standardisation of assays within molecular diagnostics...
  21. doi request reprint Interruption of poliovirus transmission in Ghana: molecular epidemiology of wild-type 1 poliovirus isolated from 1995 to 2008
    John Kofi Odoom
    Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, United Kingdom
    J Infect Dis 206:1111-20. 2012
    ....
  22. pmc Characterization of CHAT and Cox type 1 live-attenuated poliovirus vaccine strains
    Javier Martin
    Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, United Kingdom
    J Virol 76:5339-49. 2002
    ..The molecular mechanisms of attenuation and evolution of poliovirus in humans are discussed in the context of the global polio eradication initiative...
  23. pmc Rational design of genetically stable, live-attenuated poliovirus vaccines of all three serotypes: relevance to poliomyelitis eradication
    Andrew J Macadam
    NIBSC, South Mimms, Herts, UK
    J Virol 80:8653-63. 2006
    ....
  24. pmc Novel parvovirus and related variant in human plasma
    Jacqueline F Fryer
    National Institute for Biological Standards and Control, Hertfordshire, United Kingdom
    Emerg Infect Dis 12:151-4. 2006
    ..Viral DNA was detected by using highly selective polymerase chain reaction assays; 5% of pools tested positive, and amounts of DNA ranged from <500 copies/mL to >106 copies/mL plasma...
  25. ncbi request reprint Evaluation of different assays for the detection of parvovirus B19 DNA in human plasma
    Sally A Baylis
    Division of Virology, National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
    J Virol Methods 121:7-16. 2004
    ..To improve the detection of these variant viruses a novel assay has been developed and data are presented to show its use for screening pooled plasma for the presence of parvovirus B19 DNA and the variants identified recently...
  26. ncbi request reprint Mitochondrial DNA and retroviral RNA analyses of archival oral polio vaccine (OPV CHAT) materials: evidence of macaque nuclear sequences confirms substrate identity
    Neil Berry
    Division of Retrovirology, National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
    Vaccine 23:1639-48. 2005
    ..These data reinforce earlier findings on this topic providing no evidence to support the contention that poliovirus vaccination was responsible for the introduction of HIV into humans and sparking the AIDS pandemic...
  27. doi request reprint Application of deglycosylation to SDS PAGE analysis improves calibration of influenza antigen standards
    Ruth Harvey
    Division of Virology, National Institute for Biological Standards and Control, Health Protection Agency, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, United Kingdom
    Biologicals 40:96-9. 2012
    ..We found that while the final agreed HA value of the samples tested was not significantly different with or without deglycosylation, the deglycosylation step greatly improved between-laboratory agreement...
  28. doi request reprint Neurovirulence tests of three 17D yellow fever vaccine strains
    Philip D Minor
    National Institute of Biological Standards and Control, Health Protection Agency, South Mimms, Potters Bar, Hertfordshire, United Kingdom
    Biologicals 39:167-70. 2011
    ..In the test described here 168-73 was of lower virulence than either of the other two preparations...
  29. doi request reprint The polio-eradication programme and issues of the end game
    Philip D Minor
    National Institute of Biological Standards and Control, Health Protection Agency, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
    J Gen Virol 93:457-74. 2012
    ..Understanding the pathogenesis and virology of the infection is of major significance as the programme reaches its conclusion...
  30. ncbi request reprint Simian cytomegalovirus and contamination of oral poliovirus vaccines
    Sally A Baylis
    Division of Virology, National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Hertfordshire EN6 3QG, Potters Bar, UK
    Biologicals 31:63-73. 2003
    ..One poliovirus vaccine and one seed, propagated on rhesus macaque kidney cultures were found to be positive for the rhesus monkey CMV by PCR...
  31. doi request reprint Vaccine-derived poliovirus (VDPV): Impact on poliomyelitis eradication
    Philip Minor
    Division of Virology, National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshirre EN6 3QG, UK
    Vaccine 27:2649-52. 2009
    ..VDPV cannot arise from the inactivated poliovirus vaccine (IPV), but financial and logistical barriers to replace OPV with IPV remain...
  32. ncbi request reprint Lack of serologic evidence for prevalent simian virus 40 infection in humans
    Joseph J Carter
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 95:1522-30. 2003
    ..To test this hypothesis, we screened human sera for antibodies to SV40 using direct and competitive enzyme-linked immunosorbent assays (ELISAs)...
  33. ncbi request reprint When can we stop using oral poliovirus vaccine?
    Harry F Hull
    J Infect Dis 192:2033-5. 2005
  34. doi request reprint Failure to detect measles virus ribonucleic acid in bone cells from patients with Paget's disease
    Brya G Matthews
    Department of Medicine, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
    J Clin Endocrinol Metab 93:1398-401. 2008
    ..We have tested for measles virus sequences in osteoblasts and bone marrow cells collected from pagetic lesions and healthy bone...