Research Topics
Genomes and GenesSpecies | Gracjan MichlewskiSummaryAffiliation: National Institute for Medical Research Country: UK Publications
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Detail Information
Publications
RNase-assisted RNA chromatographyGracjan Michlewski
Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh EH4 2XU, United Kingdom
RNA 16:1673-8. 2010....
DGCR8 HITS-CLIP reveals novel functions for the MicroprocessorSara Macias
Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK
Nat Struct Mol Biol 19:760-6. 2012..These data provide insights in the complex role of DGCR8 in controlling the fate of several classes of RNAs...
Stimulation of pri-miR-18a processing by hnRNP A1Gracjan Michlewski
Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh EH4 2XU, UK
Adv Exp Med Biol 700:28-35. 2010....
Hormonal regulation of microRNA biogenesisSara Macias
Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh EH4 2XU, UK
Mol Cell 36:172-3. 2009..In this issue of Molecular Cell, Yamagata et al. (2009) provide insight into the complex posttranscriptional regulation of miRNA biogenesis by showing that the processing of a subset of miRNAs is inhibited by the estrogen receptor...
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesisGracjan Michlewski
Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK
Nat Struct Mol Biol 17:1011-8. 2010..Finally, hnRNP A1 binding to let-7a interferes with the binding of KSRP, which is known to promote let-7a biogenesis. We propose that hnRNP A1 and KSRP have antagonistic roles in the post-transcriptional regulation of let-7a expression...
