Enca Martin-Rendon

Summary

Affiliation: National Blood Service
Country: UK

Publications

  1. ncbi request reprint Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia
    Enca Martin-Rendon
    Stem Cell Research Laboratory, National Blood Service, Oxford Centre, The John Radcliffe Hospital, Headington, OX3 9BQ, United Kingdom
    Stem Cells 25:1003-12. 2007
  2. ncbi request reprint Patenting human genes and stem cells
    Enca Martin-Rendon
    Stem Cell Research Laboratory, NHS Blood and Transplant, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK
    Recent Pat DNA Gene Seq 1:25-34. 2007
  3. doi request reprint Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review
    Enca Martin-Rendon
    Stem Cell Research Laboratory, NHS Blood and Transplant, John Radcliffe Hospital, Headington, Oxford OX3 9BQ, UK
    Eur Heart J 29:1807-18. 2008
  4. pmc Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: factors that may influence outcomes
    David M Clifford
    Stem Cell Research Laboratory, NHS Blood and Transplant, John Radcliffe Hospital, Oxford, United Kingdom
    PLoS ONE 7:e37373. 2012
  5. doi request reprint Stem cell treatment for acute myocardial infarction
    David M Clifford
    StemCell Research Lab, NuffieldDepartment of ClinicalLaboratory Sciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD006536. 2012
  6. ncbi request reprint Intermediate filaments and the function of the dystrophin-protein complex
    Derek J Blake
    Department of Phrmacology, University of Oxford, Oxford, United Kingdom
    Trends Cardiovasc Med 12:224-8. 2002
  7. doi request reprint Route of delivery and baseline left ventricular ejection fraction, key factors of bone-marrow-derived cell therapy for ischaemic heart disease
    Susan J Brunskill
    Systematic Reviews Initiative, Clinical Research Group, NHSBT Oxford, John Radcliffe Hospital, Oxford, UK
    Eur J Heart Fail 11:887-96. 2009
  8. pmc Human cardiosphere-derived cells from patients with chronic ischaemic heart disease can be routinely expanded from atrial but not epicardial ventricular biopsies
    Helen H L Chan
    Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford, UK
    J Cardiovasc Transl Res 5:678-87. 2012
  9. ncbi request reprint Functional requirements for fukutin-related protein in the Golgi apparatus
    Chris T Esapa
    Department of Pharmacology, University of Oxford, Oxford, UK
    Hum Mol Genet 11:3319-31. 2002
  10. ncbi request reprint Iron particles for noninvasive monitoring of bone marrow stromal cell engraftment into, and isolation of viable engrafted donor cells from, the heart
    Daniel J Stuckey
    Cardiac Metabolism Research Group, Department of Physiology, Anatomy and Genetics, Sherrington Building, University of Oxford, Parks Road, Oxford, UK, OX1 3PT
    Stem Cells 24:1968-75. 2006

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia
    Enca Martin-Rendon
    Stem Cell Research Laboratory, National Blood Service, Oxford Centre, The John Radcliffe Hospital, Headington, OX3 9BQ, United Kingdom
    Stem Cells 25:1003-12. 2007
    ..These results, therefore, provide a global view of the signaling and regulatory network that controls oxygen sensing in human adult stem/progenitor cells derived from hematopoietic tissues...
  2. ncbi request reprint Patenting human genes and stem cells
    Enca Martin-Rendon
    Stem Cell Research Laboratory, NHS Blood and Transplant, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK
    Recent Pat DNA Gene Seq 1:25-34. 2007
    ..This review summarizes some of the recent published patents on pluripotency genes, gene transfer into stem cells and genetic reprogramming and takes the hematopoietic and embryonic stem cell as model systems...
  3. doi request reprint Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review
    Enca Martin-Rendon
    Stem Cell Research Laboratory, NHS Blood and Transplant, John Radcliffe Hospital, Headington, Oxford OX3 9BQ, UK
    Eur Heart J 29:1807-18. 2008
    ..To provide systematic assessment of the safety and efficacy of autologous bone marrow-derived stem cell (BMSC) transplantation in acute myocardial infarction (AMI) based on clinical evidence...
  4. pmc Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: factors that may influence outcomes
    David M Clifford
    Stem Cell Research Laboratory, NHS Blood and Transplant, John Radcliffe Hospital, Oxford, United Kingdom
    PLoS ONE 7:e37373. 2012
    ....
  5. doi request reprint Stem cell treatment for acute myocardial infarction
    David M Clifford
    StemCell Research Lab, NuffieldDepartment of ClinicalLaboratory Sciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD006536. 2012
    ..Stem cell therapy offers a promising approach to the regeneration of damaged vascular and cardiac tissue after acute myocardial infarction (AMI). This has resulted in multiple randomised controlled trials (RCTs) worldwide...
  6. ncbi request reprint Intermediate filaments and the function of the dystrophin-protein complex
    Derek J Blake
    Department of Phrmacology, University of Oxford, Oxford, United Kingdom
    Trends Cardiovasc Med 12:224-8. 2002
    ..The interaction between the DPC and the IF network may be disrupted in patients with Duchenne muscular dystrophy and in mice lacking alpha-dystrobrevin...
  7. doi request reprint Route of delivery and baseline left ventricular ejection fraction, key factors of bone-marrow-derived cell therapy for ischaemic heart disease
    Susan J Brunskill
    Systematic Reviews Initiative, Clinical Research Group, NHSBT Oxford, John Radcliffe Hospital, Oxford, UK
    Eur J Heart Fail 11:887-96. 2009
    ..This study aimed to assess whether route of delivery and baseline left ventricular ejection fraction (LVEF) of the participants may also affect the outcome of BMSC treatment in patients with AMI and ischaemic heart disease (IHD)...
  8. pmc Human cardiosphere-derived cells from patients with chronic ischaemic heart disease can be routinely expanded from atrial but not epicardial ventricular biopsies
    Helen H L Chan
    Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford, UK
    J Cardiovasc Transl Res 5:678-87. 2012
    ..6-fold more CD90+ cells than those from non-diabetic patients (n = 18). No effect of age or other co-morbidities was detected. Thus, CDCs from atrial biopsies may vary in their therapeutic potential...
  9. ncbi request reprint Functional requirements for fukutin-related protein in the Golgi apparatus
    Chris T Esapa
    Department of Pharmacology, University of Oxford, Oxford, UK
    Hum Mol Genet 11:3319-31. 2002
    ..Aberrant processing of dystroglycan caused by a mislocalized FKRP mutant could be a novel mechanism that causes congenital muscular dystrophy...
  10. ncbi request reprint Iron particles for noninvasive monitoring of bone marrow stromal cell engraftment into, and isolation of viable engrafted donor cells from, the heart
    Daniel J Stuckey
    Cardiac Metabolism Research Group, Department of Physiology, Anatomy and Genetics, Sherrington Building, University of Oxford, Parks Road, Oxford, UK, OX1 3PT
    Stem Cells 24:1968-75. 2006
    ..The magnetic properties of the iron-labeled donor cells can be used for their isolation from host tissue to enable further characterization...
  11. ncbi request reprint Stem cell plasticity
    Enca Martin-Rendon
    Stem Cell Laboratory, National Blood Service, Oxford Centre, Oxford, UK
    Br J Haematol 122:877-91. 2003
  12. ncbi request reprint The murine ortholog of the SHP-2 binding molecule, PZR accelerates cell migration on fibronectin and is expressed in early embryo formation
    Maria G Roubelakis
    Stem Cell Research Laboratory, National Blood Service, NHS Blood and Transplant Authority, Oxford OX3 5BG, UK
    J Cell Biochem 102:955-69. 2007
    ..These studies thus provide the basis for defining the function of the mPZR isoforms in vivo, particularly with respect to their roles in regulating SHP-2-dependent cell migration during development...
  13. ncbi request reprint Glycosylation defects and muscular dystrophy
    Derek J Blake
    Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, UK
    Adv Exp Med Biol 564:97-8. 2005
  14. ncbi request reprint New methods to titrate EIAV-based lentiviral vectors
    Enca Martin-Rendon
    Oxford BioMedica, Medawar Centre, Oxford Science Park, Robert Robinson Avenue, Oxford, OX4 4GA, UK
    Mol Ther 5:566-70. 2002
    ..They also allow us to determine the integration efficiency of different vector genomes. This technology has proved very useful, especially in the absence of marker genes and where vectors express multiple genes...
  15. pmc Bone marrow-derived stromal cells home to and remain in the infarcted rat heart but fail to improve function: an in vivo cine-MRI study
    Carolyn A Carr
    Cardiac Metabolism Research Group, Dept of Physiology, Anatomy and Genetics, Sherrington Bldg, Univ of Oxford, Parks Road Oxford, United Kingdom OX1 3PT
    Am J Physiol Heart Circ Physiol 295:H533-42. 2008
    ..However, no significant improvement in any measure of cardiac function was observed at any time. We conclude that cultured BMSCs are not the optimal cell population to treat the infarcted heart...