Research Topics
Genomes and GenesSpecies | D KuhSummaryAffiliation: National Institute for Medical Research Country: UK Publications
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Publications
A life course approach to healthy ageing: the HALCyon programmeD Kuh
MRC Unit for Lifelong Health and Ageing, London, UK
Public Health 126:193-5. 2012..In this symposium, HALCyon co-investigators reported the first wave of findings from five of the eight work packages...
Psychometric evaluation and predictive validity of Ryff's psychological well-being items in a UK birth cohort sample of womenRosemary A Abbott
Department of Psychiatry, University of Cambridge, Box 189, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 2QQ, UK
Health Qual Life Outcomes 4:76. 2006..Ryff has proposed a multidimensional model of psychological well-being and her questionnaire items are widely used but their latent structure and factorial validity remains contentious...
Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth CohortMax Henderson
King s College London, Institute of Psychiatry, Department of Psychological Medicine, Weston Education Centre, Cutcombe Road, London SE5 9RJ UK
BMC Psychiatry 11:37. 2011..We aimed to investigate if psychiatric disorder was associated with a higher risk of mortality and whether any excess mortality was due to suicide, or explained by other health or socioeconomic risk factors...
Lifetime body size and reproductive factors: comparisons of data recorded prospectively with self reports in middle ageBenjamin J Cairns
Cancer Epidemiology Unit, University of Oxford, Oxford, UK
BMC Med Res Methodol 11:7. 2011....
Lifetime cognitive performance is associated with midlife physical performance in a prospective national birth cohort studyDiana Kuh
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, United Kingdom
Psychosom Med 71:38-48. 2009..To examine whether measures of cognitive performance across life are related to physical performance at age 53 years, allowing for potential confounders...
Grip strength, postural control, and functional leg power in a representative cohort of British men and women: associations with physical activity, health status, and socioeconomic conditionsDiana Kuh
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 1 19 Torrington Place, London, United Kingdom, WC1E 6BT
J Gerontol A Biol Sci Med Sci 60:224-31. 2005....
Developmental origins of midlife physical performance: evidence from a British birth cohortDiana Kuh
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, UK
Am J Epidemiol 164:110-21. 2006..This study is the first to show that childhood growth and development affect midlife performance; prevention of disability and frailty in later life may need to start early...
Do childhood cognitive ability or smoking behaviour explain the influence of lifetime socio-economic conditions on premature adult mortality in a British post war birth cohort?Diana Kuh
MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 33 Bedford Place, London WC1B 5JU, United Kingdom
Soc Sci Med 68:1565-73. 2009..These findings were similar for cardiovascular and cancer mortality...
Developmental origins of midlife grip strength: findings from a birth cohort studyDiana Kuh
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
J Gerontol A Biol Sci Med Sci 61:702-6. 2006..We tested whether prepubertal growth, pubertal growth, or the development of motor and cognitive capabilities was associated with midlife muscle strength independently of other determinants of grip strength...
Offspring birth weight, gestational age and maternal characteristics in relation to glucose status at age 53 years: evidence from a national birth cohortD Kuh
MRC National Survey of Health and Development, MRC Unit for Lifelong Health and Ageing, Royal Free and University College Medical School, London, UK
Diabet Med 25:530-5. 2008..We investigated pathways linking offspring birth weight to maternal diabetes risk in later life by taking into account a range of prospective early-life and adult maternal factors...
A life course perspective on telomere length and social inequalities in agingDiana Kuh
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, 1 19 Torrington Place, London WC1E, UK
Aging Cell 5:579-80. 2006..Longitudinal studies will be needed to test the idea that social class in adult life, or in childhood, influences the rate of change in telomere length in peripheral blood samples...
Age at birth of first child and coronary heart disease risk factors at age 53 years in men and women: British birth cohort studyR Hardy
Medical Research Council Unit for Lifelong Health and Ageing, 33 Bedford Place, London, WC1B 5JU, UK
J Epidemiol Community Health 63:99-105. 2009..To investigate whether the associations are explained by childhood predictors of age at parenthood or adult lifestyle factors related to child rearing...
Cardiovascular risk at age 53 years in relation to the menopause transition and use of hormone replacement therapy: a prospective British birth cohort studyD Kuh
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 1-19 Torrington Place, London WC1E 6BT, UK
BJOG 112:476-85. 2005..The lower levels of metabolic risk factors for women on hormone replacement therapy may protect against future cardiovascular disease or may be overwhelmed by other adverse, and as yet unknown, effects of hormone replacement therapy...
Is adiposity across life associated with subsequent hysterectomy risk? Findings from the 1946 British birth cohort studyR Cooper
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, UK
BJOG 115:184-92; discussion 192. 2008..To examine the associations between adiposity at time points from early life onwards and subsequent hysterectomy risk...
Birthweight, childhood growth and risk of breast cancer in a British cohortB L Stavola
Cancer and Public Health Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
Br J Cancer 83:964-8. 2000..5 kg) but tall at 7 years (>/= 1.22 m) had a four-fold increase (RR = 4.01; 95% CI = 1.82-8.83). These results suggest that the effect of birthweight on breast cancer risk may be modulated by childhood growth...
Socioeconomic position and hysterectomy: a cross-cohort comparison of women in Australia and Great BritainR Cooper
MRC National Survey of Health and Development, Department of Epidemiology and PublicHealth, University College London, London, UK
J Epidemiol Community Health 62:1057-63. 2008..To examine the associations between indicators of socioeconomic position (SEP) and hysterectomy in two Australian and two British cohorts...
Central and total obesity in middle aged men and women in relation to lifetime socioeconomic status: evidence from a national birth cohortC Langenberg
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Epidemiol Community Health 57:816-22. 2003..To investigate the influence of social class in childhood, young adulthood and middle age, and intergenerational mobility, on adult central and total obesity...
The influence of childhood weight and socioeconomic status on change in adult body mass index in a British national birth cohortR Hardy
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
Int J Obes Relat Metab Disord 24:725-34. 2000..To investigate the effect of childhood weight and childhood socioeconomic status on the pattern of change in body mass index (BMI) between 20 and 43 years...
Smoking, body mass index, socioeconomic status and the menopausal transition in a British national cohortR Hardy
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London
Int J Epidemiol 29:845-51. 2000..This study investigates whether cigarette smoking, body mass index (BMI) and socioeconomic status are independently associated with age at menopausal transition...
Number of children and coronary heart disease risk factors in men and women from a British birth cohortR Hardy
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
BJOG 114:721-30. 2007..To examine the association between number of children and coronary heart disease (CHD) risk factors in women and men...
Symptoms of depression and anxiety, and change in body mass index from adolescence to adulthood: results from a British birth cohortD Gaysina
MRC Unit for Lifelong Health and Ageing, University College London, London, UK
Psychol Med 41:175-84. 2011..We aimed to investigate the association between adolescent- and adult-onset affective symptoms and body mass index (BMI) change from age 15 to 53 years...
Validity of age at menarche self-reported in adulthoodR Cooper
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, University College London, London, UK
J Epidemiol Community Health 60:993-7. 2006..To test the validity of age at menarche self-reported in adulthood and examine whether socioeconomic position, education, experience of gynaecological events and psychological symptoms influence the accuracy of recall...
Cognitive function across the life course and the menopausal transition in a British birth cohortHelen S Kok
MRC National Survey of Health and Development, Royal Free and University College London Medical School, Department of Epidemiology and Public Health, England
Menopause 13:19-27. 2006..These findings suggest that common environmental or genetic factors, operating through long-term or lifelong hormonal mechanisms, may influence the timing of natural menopause and lifetime cognitive function...
Social circumstances and education: life course origins of social inequalities in metabolic risk in a prospective national birth cohortClaudia Langenberg
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, England, United Kingdom
Am J Public Health 96:2216-21. 2006..We investigated the relative importance of education and childhood and adult social class in the risk of metabolic syndrome...
Birth weight, childhood size, and muscle strength in adult life: evidence from a birth cohort studyDiana Kuh
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, England
Am J Epidemiol 156:627-33. 2002..As the inevitable loss of muscle fibers proceeds in old age, a deficit in the number of fibers could threaten quality of life and independence...
The role of BMI across the life course in the relationship between age at menarche and diabetes, in a British Birth CohortM B Pierce
MRC Unit for Lifelong Health and Ageing, London, UK
Diabet Med 29:600-3. 2012..We investigated the relationship between age at menarche and diabetes, and whether childhood, adolescent or adult BMI attenuates this relationship...
Does early growth influence timing of the menopause? Evidence from a British birth cohortR Hardy
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London WC1E 6BT, UK
Hum Reprod 17:2474-9. 2002..This study investigates whether birthweight, childhood body size, having been breastfed and early socioeconomic circumstances are associated with age at menopause...
Mortality in adults aged 26-54 years related to socioeconomic conditions in childhood and adulthood: post war birth cohort studyDiana Kuh
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London, London WC1E 6BT
BMJ 325:1076-80. 2002..To examine premature mortality in adults in relation to socioeconomic conditions in childhood and adulthood...
Socio-economic position across the life course and hysterectomy in three British cohorts: a cross-cohort comparative studyRachel Cooper
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, University College London, UK
BJOG 112:1126-33. 2005....
Birth weight and cognitive function in the British 1946 birth cohort: longitudinal population based studyM Richards
MRC National Survey of Health and Development, University College London, London WC1E 6BT, UK
BMJ 322:199-203. 2001..The effect at this age largely explains associations between birth weight and cognitive function at subsequent ages. Similarly, the association between birth weight and education was accounted for partly by earlier cognitive scores...
Childhood socioeconomic circumstances and adult height and leg length in central and eastern EuropeE Webb
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Epidemiol Community Health 62:351-7. 2008..This study will determine whether similar associations are observable in settings with different social histories, and will assess whether adult leg length is more strongly associated than adult height...
Characterisation of smoking behaviour across the life course and its impact on decline in lung function and all-cause mortality: evidence from a British birth cohortS Clennell
MRC National Survey of Health and Development, University College and Royal Free Medical School, 33 Bedford Place, London WCIB 5JU, UK
J Epidemiol Community Health 62:1051-6. 2008..To describe smoking trajectories from early adolescence into mid-life and to examine the effects of these trajectories on health and all-cause mortality...
Cessation of hormone replacement therapy after reports of adverse findings from randomized controlled trials: evidence from a British Birth CohortGita Mishra
National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, England
Am J Public Health 96:1219-25. 2006..CONCLUSIONS: These decreases coincided with the announced cessation of a large US clinical trial of HRT. This publicity may have had a differential influence on the immediate decline in HRT use by various groups of British women...
Women's health in mid-life: life course social roles and agency as qualityAnne McMunn
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Soc Sci Med 63:1561-72. 2006..This study highlights the need to develop measures of role quality specifically designed to capture agency aspects of social roles...
Birthweight, childhood social class, and change in adult blood pressure in the 1946 British birth cohortRebecca Hardy
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, WC1E 6BT, London, UK
Lancet 362:1178-83. 2003..The negative effect of birthweight on systolic blood pressure has been suggested to be initiated in utero and amplified with age. We aimed to investigate this hypothesis...
Birthweight, childhood growth, and blood pressure at 43 years in a British birth cohortRebecca Hardy
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
Int J Epidemiol 33:121-9. 2004..Low birthweight is associated with high blood pressure in later life, but it is unclear whether the association is confounded with or modified by maternal and socioeconomic factors or childhood growth...
Birthweight, postnatal growth and cognitive function in a national UK birth cohortMarcus Richards
MRC National Survey of Health and Development, University College London, UK
Int J Epidemiol 31:342-8. 2002..We therefore investigated the independent effects of birthweight and postnatal height adjusted for postnatal weight on cognitive function and educational attainment while controlling for family background...
Body weight through adult life and risk of urinary incontinence in middle-aged women: results from a British prospective cohortG D Mishra
MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College and Royal Free Medical School, London, UK
Int J Obes (Lond) 32:1415-22. 2008..To determine whether the onset and duration of being overweight or obese are associated with symptoms of urinary incontinence...
Birth weight, childhood growth and abdominal obesity in adult lifeD Kuh
Medical Research Council National Survey of Health and Development, Royal Free and University College, London, UK
Int J Obes Relat Metab Disord 26:40-7. 2002..To examine the relationship of adult abdominal obesity to birth weight, childhood growth and lifetime socioeconomic circumstances...
Breast cancer in relation to childhood parental divorce and early adult psychiatric disorder in a British birth cohortA U Lokugamage
Department of Obstetrics and Gynaecology, Royal Free and University College Medical School, London, UK
Psychol Med 36:1307-12. 2006..A meta-analysis is needed that uses data from all available cohort studies and investigates possible interactive effects on breast cancer risk...
Women's health in midlife: findings from a British birth cohort studyDiana Kuh
MRC Research Scientist and Reader, Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
J Br Menopause Soc 9:55-60. 2003..Of particular interest are their results linking ovarian ageing to developmental factors. Replication of these findings in other life course cohorts is being sought...
Life course social roles and women's health in mid-life: causation or selection?Anne McMunn
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Epidemiol Community Health 60:484-9. 2006....
Social and environmental conditions across the life course and age at menopause in a British birth cohort studyRebecca Hardy
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London WC1E 6BT, UK
BJOG 112:346-54. 2005..Childhood nutrition, cognition and emotional stress possibly underlie the social gradient...
Lifetime risk factors for women's psychological distress in midlifeDiana Kuh
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, Gower Street Campus, 1 19 Torrington Place, London WC1E 6BT, UK
Soc Sci Med 55:1957-73. 2002..More attention to a long term temporal perspective is warranted in research on the causes of psychological distress in women at midlife...
Body mass index trajectories and age at menopause in a British birth cohortRebecca Hardy
Medical Research Council Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
Maturitas 59:304-14. 2008..This study investigates the influence of body mass index (BMI) at ages 15, 20, 26, 36, and 43, and of BMI trajectories from 20 to 36 years on the timing of menopause and hormone therapy (HT) use until age 57 years...
Role of lifetime body mass index in the association between age at puberty and adult lipids: findings from men and women in a British birth cohortMary B Pierce
MRC Unit for Lifelong Health and Ageing, London, United Kingdom
Ann Epidemiol 20:676-82. 2010..The relationship between puberty and lipids is unclear. Our aim was to assess whether age at puberty was associated with triglyceride and total low-density lipoprotein and high-density lipoprotein cholesterol at age 53 years...
Objectively measured physical capability levels and mortality: systematic review and meta-analysisRachel Cooper
MRC Unit for Lifelong Health and Ageing and Division of Population Health, University College London, London WC1B 5JU
BMJ 341:c4467. 2010....
Objective measures of physical capability and subsequent health: a systematic reviewRachel Cooper
MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, London, UK
Age Ageing 40:14-23. 2011....
Is there an association between hysterectomy and subsequent adiposity?Rachel Cooper
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, UK
Maturitas 58:296-307. 2007....
Life course variations in the associations between FTO and MC4R gene variants and body sizeRebecca Hardy
MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, 33 Bedford Place, London, UK
Hum Mol Genet 19:545-52. 2010..Studies of the aetiology of obesity spanning different age groups may identify age-specific determinants of weight gain...
A longitudinal investigation of the impact of typology of urinary incontinence on quality of life during midlife: results from a British prospective studyGita D Mishra
MRC Unit for Lifelong Health and Ageing, University College and Royal Free Medical School, 33 Bedford Place, London WC1B5JU, United Kingdom
Maturitas 64:246-8. 2009..More research is needed to understand the mechanism that link childhood enuresis to being in the 'chronic' group for urge and severe incontinence...
Intake of B vitamins in childhood and adult life in relation to psychological distress among women in a British birth cohortGita D Mishra
MRC National Survey of Health and Development, Royal Free and University, College Medical School, London WC1E 6BT, UK
Public Health Nutr 12:166-74. 2009..Lower levels of B vitamins (particularly folate, vitamin B12 and vitamin B6) may be associated with psychological distress. Little is known about the impact of childhood nutrition on psychological distress in adult life...
Menopausal status and physical performance in midlife: findings from a British birth cohort studyRachel Cooper
MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, London, UK
Menopause 15:1079-85. 2008..To test the associations of menopausal status, timing of menopause, and hysterectomy with physical performance at age 53 years...
Early life circumstances and their impact on menarche and menopauseGita D Mishra
MRC Unit for Lifelong Health and Ageing, University College and Royal Free Medical School, London, UK
Womens Health (Lond Engl) 5:175-90. 2009..It examines possible explanations of the associations found, including life history theory, and discusses areas for future research...
Hysterectomy and subsequent psychological health: findings from a British birth cohort studyRachel Cooper
MRC Unit for Lifelong Health and Ageing, 33 Bedford Place, London, WC1B 5JU, UK
J Affect Disord 115:122-30. 2009..We aimed to test the association between hysterectomy and subsequent psychological health and examine variation in this association by characteristics of hysterectomy...
A structured approach to modelling the effects of binary exposure variables over the life courseGita Mishra
MRC Unit for Lifelong Health and Ageing, University College and Royal Free Medical School, London, UK
Int J Epidemiol 38:528-37. 2009..This article highlights potential issues in the interpretation of results obtained from such an approach...
A life course approach to reproductive health: theory and methodsGita D Mishra
MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College and Royal Free Medical School, 33 Bedford Place, London WC1B 5JU, United Kingdom
Maturitas 65:92-7. 2010..This approach has implications for the development of effective health policy that moves beyond identifying not only the type of intervention but also the most appropriate time across life to intervene...
Timing of menarche, childbearing and hysterectomy riskRachel Cooper
MRC Unit for Lifelong Health and Ageing, London, UK
Maturitas 61:317-22. 2008....
Perceived change in quality of life during the menopauseGita Mishra
Department of Epidemiology and Public Health Gower Street Campus, MRC National Survey of Health and Development Royal Free and University College Medical School, 1 19, Torrington Place, London WC1E 6BT, UK
Soc Sci Med 62:93-102. 2006..05) domain. In terms of the three QoL domains, women's experience of the menopausal transition appears complex, potentially involving a range of other factors and influences in their lives, and is by no means overwhelmingly negative...
Age at puberty and adult blood pressure and body size in a British birth cohort studyRebecca Hardy
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
J Hypertens 24:59-66. 2006..To investigate the association between age at puberty and blood pressure at age 53 years...
Commentary: BMI and mortality in the elderly--a life course perspectiveRebecca Hardy
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 1-19 Torrington Place, London WC1E 6BT, UK
Int J Epidemiol 35:179-80. 2006
Cohort Profile: The 1946 National Birth Cohort (MRC National Survey of Health and Development)Michael Wadsworth
MRC National Survey of Health and Development, Royal Free and UCL Medical School, Department of Epidemiology and Public Health, 1-19 Torrington Place, London WC1E 6BT, UK
Int J Epidemiol 35:49-54. 2006
Commentary: The relationship between parity and overweight--a life course perspectiveGita Mishra
MRC National Survey of Health and Development, University College and Royal Free Medical School, 1-19 Torrington Place, London WC1E 6BT, UK
Int J Epidemiol 36:102-3. 2007
Are the effects of risk factors for timing of menopause modified by age? Results from a British birth cohort studyGita Mishra
Medical Research Council National Survey of Health and Development, University College and Royal Free Medical School, London, UK
Menopause 14:717-24. 2007..This study investigated the influence of mother's age at menopause, early life and adult behavioral factors on the timing of menopause until age 57 years, and whether these effects vary according to the women's age at menopause...
Childhood cognitive ability and age at menopause: evidence from two cohort studiesDiana Kuh
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London
Menopause 12:475-82. 2005..To investigate whether poorer cognitive ability in childhood is associated with an earlier menopause...
Childhood cognitive ability and deaths up until middle age: a post-war birth cohort studyDiana Kuh
Department of Epidemiology and Public Health, Royal Free and University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Int J Epidemiol 33:408-13. 2004..We examined mortality in relation to cognitive ability at age 8 years in a birth cohort and investigated these possible reasons...
Sexual functioning throughout menopause: the perceptions of women in a British cohortGita Mishra
Medical Research Council National Survey of Health and Development, University College and Royal Free Medical School, London, United Kingdom
Menopause 13:880-90. 2006..We examine relationships between women's reports of a change in sex life and difficulties with intercourse and their experience of menopausal transition, use of hormone therapy, and hysterectomy...
The role of lifestyle behaviors on 20-year cognitive declineD Cadar
MRC Unit for Lifelong Health and Ageing, London WC1B 5JU, UK Faculty of Population Health Sciences, University College London, London WC1E 6BT, UK
J Aging Res 2012:304014. 2012..Adopting positive health behaviors from early midlife may be beneficial in reducing the rate of cognitive decline and ultimately reducing the risk of dementia...
Parenting practices and intergenerational associations in cognitive abilityM Byford
Department of Epidemiology and Public Health, University College London Medical School, London, UK
Int J Epidemiol 41:263-72. 2012..Parenting practices are known to influence offspring cognitive development, but the extent to which these mediate intergenerational continuities and discontinuities in cognitive ability has not been adequately studied...
Dietary calcium and vitamin D intakes in childhood and throughout adulthood and mammographic density in a British birth cohortG Mishra
MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, London, UK
Br J Cancer 99:1539-43. 2008..53 s.d. lower percent breast density than those in the lowest fifth (P-value <0.01 for linear trend)...
The relationship between fatigue and psychiatric disorders: evidence for the concept of neurastheniaSamuel B Harvey
Institute of Psychiatry, King s College London, London, UK
J Psychosom Res 66:445-54. 2009..We also aimed to investigate the psychological outcome of any individuals with fatigue...
Change in psychological and vasomotor symptom reporting during the menopauseRebecca Hardy
Department of Epidemiology and Public Health, Royal Free and University College Medical School, Medical Research Council National Survey of Health and Development, Gower Street Campus, 1 19 Torrington Place, London WC1E 6BT, UK
Soc Sci Med 55:1975-88. 2002..Factors other than the menopause should be considered, such as concurrent life events and past experiences and behaviours, when considering the treatment of psychological symptoms in women during middle life...
Influence of height, leg and trunk length on pulse pressure, systolic and diastolic blood pressureClaudia Langenberg
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, 1 19 Torrington Place, London WC1 6BT, UK
J Hypertens 21:537-43. 2003..To compare the effects of height, leg and trunk length on pulse pressure (PP), systolic (SBP) and diastolic blood pressure (DBP) in men and women...
Estimation of secular trends in adult height, and childhood socioeconomic circumstances in three Eastern European populationsElizabeth Alice Webb
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Econ Hum Biol 6:228-36. 2008..These results suggest that secular trends in height mirror, but are not wholly explained by, trends in socioeconomic circumstances in early life...
Lung function and cognitive ability in a longitudinal birth cohort studyMarcus Richards
MRC National Survey of Health and Development, University College London, UK
Psychosom Med 67:602-8. 2005..The objective of this study was to examine the association between forced expiratory volume in 1 second (FEV1) and cognitive ability in midlife in the normal population...
Influence of short stature on the change in pulse pressure, systolic and diastolic blood pressure from age 36 to 53 years: an analysis using multilevel modelsClaudia Langenberg
Department of Epidemiology and Public Health, University College London Medical School, 1 19 Torrington Place, London WC1E 6BT, UK
Int J Epidemiol 34:905-13. 2005..It is unclear how these adult measures of childhood growth influence the change in blood pressure as it increases with age...
Life course epidemiologyD Kuh
Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, University College London and Royal Free Medical School, Gower Street Campus, 1-19 Torrington Place, London WC1E 6BT, U.K
J Epidemiol Community Health 57:778-83. 2003
"The pump don't work, 'cause the vandals took the handles"Diana Kuh
MRC National Survey of Health and Development, Royal Free and University College Medical School, Department of Epidemiology and Public Health, London, UK
Epidemiology 15:517-8. 2004
Women's body dissatisfaction, social class, and social mobilityLindsay McLaren
Department of Community Health Sciences, Faculty of Medicine, University of Calgary, G230 Health Sciences Building, 3330 Hospital Drive NW, Calgary, Alta T2N 4N1, Canada
Soc Sci Med 58:1575-84. 2004....
Infant developmental milestones and subsequent cognitive functionGraham K Murray
Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
Ann Neurol 62:128-36. 2007..We hypothesized that earlier attainment of developmental milestones would be associated with better subsequent intellectual performance throughout the range of abilities, rather than confined to extremes...
Prenatal factors, childhood growth trajectories and age at menarcheIsabel dos Santos Silva
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Int J Epidemiol 31:405-12. 2002..The mechanisms underlying this association are not clear, however, as birthweight is a predictor of body size in childhood, and a large body size is known to be associated with an early onset of menarche...
Body dissatisfaction in midlife womenLindsay McLaren
Centre for Health and Policy Studies, Department of Community Health Sciences, University of Calgary, G230 Health Sciences Bldg, 3330 Hospital Dr NW, Calgary AB, Canada
J Women Aging 16:35-54. 2004..Adjusting for BMI, women who were happy with their weight were more likely to report distress about other aspects of their appearance. We suggest that body dissatisfaction in women of this age group merits further attention...
Country of birth, country of residence, and menopausal transitions and symptoms: British birth cohort and Australian Longitudinal Study on Women's HealthChristina Lee
School of Psychology, University of Queensland, St Lucia
Aust N Z J Public Health 28:144-51. 2004..To explore endocrine-related and general symptoms among three groups of middle-aged women defined by country of birth and country of residence, in the context of debates about biological, cultural and other factors in menopause...
Childhood socioeconomic status predicts physical functioning a half century laterJack M Guralnik
Laboratory of Epidemiology, Demography aand Biometry, National Institute on Aging, Bethesda, MD 20892, USA
J Gerontol A Biol Sci Med Sci 61:694-701. 2006..Relating childhood socioeconomic environment to midlife functional status provides a life course perspective on childhood factors associated with poor and good health status later in life...
The relationship between early personality and midlife psychological well-being: evidence from a UK birth cohort studyRosemary A Abbott
Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge, UK
Soc Psychiatry Psychiatr Epidemiol 43:679-87. 2008..The aim of this study was to examine long range associations between Eysenck's personality dimensions and psychological well-being in midlife...
Child-to-adult body mass index and height trajectories: a comparison of 2 British birth cohortsLeah Li
Centre for Paediatric Epidemiology and Biostatistics Medical Research Council Centre of Epidemiology for Child Health, Institute of Child Health, University College London, 30 Guilford Street, London WC1N1EH, United Kingdom
Am J Epidemiol 168:1008-15. 2008..1% vs. 10.8% in males and 23.7% vs. 14.8% in females). Changes in height and adiposity over a relatively short period of 12 years suggest the likelihood of opposing trends of influences on later disease risk in these populations...
Childhood cognitive ability and adult mental health in the British 1946 birth cohortStephani L Hatch
Columbia University, New York, NY, USA
Soc Sci Med 64:2285-96. 2007..In addition, the underlying mechanisms responsible for the gender-specific link between childhood cognitive ability and the risk of experiencing internalising disorders in mid-adulthood warrants further consideration...
The contribution of childhood and adult socioeconomic position to adult obesity and smoking behaviour: an international comparisonChris Power
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, WC1N 1EH London, UK
Int J Epidemiol 34:335-44. 2005....
A life course approach to healthy aging, frailty, and capabilityDiana Kuh
J Gerontol A Biol Sci Med Sci 62:717-21. 2007
Women's body satisfaction at midlife and lifetime body size: a prospective studyLindsay McLaren
Department of Community Health Sciences, University of Calgary, Alberta, Canada
Health Psychol 22:370-7. 2003..Attention to these factors across the life span is necessary to understand body dissatisfaction in women at midlife...
Patterns of interphalangeal hand joint involvement of osteoarthritis among men and women: a British cohort studyJason Poole
Southampton General Hospital, University of Southampton, Southampton, UK
Arthritis Rheum 48:3371-6. 2003..The data suggest that the genetic or metabolic influences underlying this particular variant of OA acts similarly in both sexes...
Meeting report on the 3rd International Congress on Developmental Origins of Health and Disease (DOHaD)Matthew W Gillman
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
Pediatr Res 61:625-9. 2007..Improving the environment to which an individual is exposed during development may be as important as any other public health effort to enhance population health world wide...
Postnatal depression and the original mother-child relationship: a prospective cohort studyLindsay McLaren
Department of Community Health Sciences, University of Calgary, 3330 Hospital Dr NW, Calgary, AB, Canada T2N 4N1
J Affect Disord 100:211-9. 2007..Previous studies assessing the role of early mother-child relationship as a risk factor for postnatal depression have been cross-sectional and/or retrospective in nature...
A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectivesYoav Ben-Shlomo
Int J Epidemiol 31:285-93. 2002
