Anne E King

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi Regulation of natural antibiotic expression by inflammatory mediators and mimics of infection in human endometrial epithelial cells
    Anne E King
    MRC Human Reproductive Sciences Unit and Department of Reproductive and Developmental Sciences, University of Edinburgh, Centre for Reproductive Biology, 37 Chalmers Street, Edinburgh EH3 9ET, UK
    Mol Hum Reprod 8:341-9. 2002
  2. pmc Innate immune defences in the human endometrium
    Anne E King
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Chancellor s Building, 49 Little France Crescent, Edinburgh, UK
    Reprod Biol Endocrinol 1:116. 2003
  3. ncbi Differential expression of the natural antimicrobials, beta-defensins 3 and 4, in human endometrium
    Anne E King
    MRC Human Reproductive Sciences Unit, University of Edinburgh, Academic Centre, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
    J Reprod Immunol 59:1-16. 2003
  4. ncbi Elafin in human endometrium: an antiprotease and antimicrobial molecule expressed during menstruation
    Anne E King
    Medical Research Council Human Reproductive Sciences Unit, University of Edinburgh, Centre for Reproductive Biology, Edinburgh, United Kingdom EH16 4SB
    J Clin Endocrinol Metab 88:4426-31. 2003
  5. ncbi Hormonal contraception can suppress natural antimicrobial gene transcription in human endometrium
    Diana C Fleming
    Human Reproductive Sciences Unit, Medical Research Council, Academic Centre, Edinburgh, United Kingdom
    Fertil Steril 79:856-63. 2003
  6. ncbi Differential regulation of secretory leukocyte protease inhibitor and elafin by progesterone
    Anne E King
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Chancellor s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK
    Biochem Biophys Res Commun 310:594-9. 2003
  7. doi Differential expression and regulation of nuclear oligomerization domain proteins NOD1 and NOD2 in human endometrium: a potential role in innate immune protection and menstruation
    Anne E King
    Reproductive and Developmental Sciences, Centre for Reproductive Biology, The Queen s Medical Research Institute, Edinburgh, UK
    Mol Hum Reprod 15:311-9. 2009
  8. ncbi Inflammatory mediators and endometrial function--focus on the perivascular cell
    Rodney W Kelly
    Human Reproductive Sciences Unit, Medical Research Council, Centre for Reproductive Biology, University of Edinburgh, UK
    J Reprod Immunol 57:81-93. 2002
  9. doi Expression of secretory leukocyte protease inhibitor and elafin in human fallopian tube and in an in-vitro model of Chlamydia trachomatis infection
    Anne E King
    Reproductive and Developmental Sciences, University of Edinburgh, The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    Hum Reprod 24:679-86. 2009
  10. doi Innate immunity and disorders of the female reproductive tract
    Andrew W Horne
    The Queen s Medical Research Institute, Reproductive and Developmental Sciences, Centre for Reproductive Biology, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    Reproduction 135:739-49. 2008

Collaborators

Detail Information

Publications14

  1. ncbi Regulation of natural antibiotic expression by inflammatory mediators and mimics of infection in human endometrial epithelial cells
    Anne E King
    MRC Human Reproductive Sciences Unit and Department of Reproductive and Developmental Sciences, University of Edinburgh, Centre for Reproductive Biology, 37 Chalmers Street, Edinburgh EH3 9ET, UK
    Mol Hum Reprod 8:341-9. 2002
    ..g. HBD2) are inducible allowing maximal antimicrobial activity during infection. Natural antimicrobials will have an important role in endometrium in protecting against infection...
  2. pmc Innate immune defences in the human endometrium
    Anne E King
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Chancellor s Building, 49 Little France Crescent, Edinburgh, UK
    Reprod Biol Endocrinol 1:116. 2003
    ....
  3. ncbi Differential expression of the natural antimicrobials, beta-defensins 3 and 4, in human endometrium
    Anne E King
    MRC Human Reproductive Sciences Unit, University of Edinburgh, Academic Centre, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
    J Reprod Immunol 59:1-16. 2003
    ..In addition, expression of HBD3 will be upregulated during infection allowing an increased innate immune response at this time...
  4. ncbi Elafin in human endometrium: an antiprotease and antimicrobial molecule expressed during menstruation
    Anne E King
    Medical Research Council Human Reproductive Sciences Unit, University of Edinburgh, Centre for Reproductive Biology, Edinburgh, United Kingdom EH16 4SB
    J Clin Endocrinol Metab 88:4426-31. 2003
    ..This is attributable to the presence of infiltrating leukocytes and increased inflammatory signaling. Elafin will regulate proteolytic enzymes during menstruation and will contribute to the innate defense against uterine infection...
  5. ncbi Hormonal contraception can suppress natural antimicrobial gene transcription in human endometrium
    Diana C Fleming
    Human Reproductive Sciences Unit, Medical Research Council, Academic Centre, Edinburgh, United Kingdom
    Fertil Steril 79:856-63. 2003
    ....
  6. ncbi Differential regulation of secretory leukocyte protease inhibitor and elafin by progesterone
    Anne E King
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Chancellor s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK
    Biochem Biophys Res Commun 310:594-9. 2003
    ....
  7. doi Differential expression and regulation of nuclear oligomerization domain proteins NOD1 and NOD2 in human endometrium: a potential role in innate immune protection and menstruation
    Anne E King
    Reproductive and Developmental Sciences, Centre for Reproductive Biology, The Queen s Medical Research Institute, Edinburgh, UK
    Mol Hum Reprod 15:311-9. 2009
    ..NODs may have a role in innate immune protection in the uterus and NOD2 may regulate inflammation associated with menstruation...
  8. ncbi Inflammatory mediators and endometrial function--focus on the perivascular cell
    Rodney W Kelly
    Human Reproductive Sciences Unit, Medical Research Council, Centre for Reproductive Biology, University of Edinburgh, UK
    J Reprod Immunol 57:81-93. 2002
    ..The perivascular cell in endometrium is pivotal in both menstruation and early pregnancy and we need to understand this cell better to devise more effective medical treatment for menstrual dysfunction...
  9. doi Expression of secretory leukocyte protease inhibitor and elafin in human fallopian tube and in an in-vitro model of Chlamydia trachomatis infection
    Anne E King
    Reproductive and Developmental Sciences, University of Edinburgh, The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    Hum Reprod 24:679-86. 2009
    ..They have been demonstrated at multiple mucosal surfaces including those of the female reproductive tract...
  10. doi Innate immunity and disorders of the female reproductive tract
    Andrew W Horne
    The Queen s Medical Research Institute, Reproductive and Developmental Sciences, Centre for Reproductive Biology, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    Reproduction 135:739-49. 2008
    ....
  11. doi Oestrogen and progesterone regulation of inflammatory processes in the human endometrium
    Anne E King
    University of Edinburgh, Centre for Reproductive Biology, The Queen s Medical Research Institute, United Kingdom
    J Steroid Biochem Mol Biol 120:116-26. 2010
    ....
  12. ncbi PGE/cAMP and GM-CSF synergise to induce a pro-tolerance cytokine profile in monocytic cell lines
    Vivien Grant
    Medical Research Council, Human Reproductive Sciences Unit, University of Edinburgh Chancellor s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK
    Biochem Biophys Res Commun 331:187-93. 2005
    ..Monocytes modified in such a way could provide a pro-tolerant environment (high IL-10, low IL-12) for antigen presentation by dendritic cells and thus may contribute to a normally permissive milieu, e.g., for food absorption...
  13. pmc Prokineticin-1: a novel mediator of the inflammatory response in third-trimester human placenta
    Fiona C Denison
    Department of Reproductive and Developmental Sciences, Centre for Reproductive Biology, University of Edinburgh, Edinburgh, United Kingdom
    Endocrinology 149:3470-7. 2008
    ..Using double-immunofluorescent immunohistochemistry, PKR1 colocalized with IL-8 and COX-2 in placenta. These data suggest that PK1 may have a novel role as a mediator of the inflammatory response in placenta...
  14. ncbi Neurotrophin-induced preprotachykinin-A gene promoter modulation in organotypic rat spinal cord culture
    Kathryn J Hilton
    Institute of Membrane and Systems Biology, University of Leeds, Leeds, UK
    J Neurochem 98:690-9. 2006
    ..The functional consequences of such transcriptional changes within central peptidergic circuitry and their relevance to chronic pain are considered...