Rebecca Hardy

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. pmc Childhood cognitive ability and adult mental health in the British 1946 birth cohort
    Stephani L Hatch
    Columbia University, New York, NY, USA
    Soc Sci Med 64:2285-96. 2007
  2. pmc Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme
    Rebecca Hardy
    Medical Research Council Unit for Lifelong Health and Ageing and Institute of Epidemiology and Health Care, University College London, London, United Kingdom
    PLoS ONE 8:e56483. 2013
  3. pmc Is chair rise performance a useful measure of leg power?
    Rebecca Hardy
    MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, UK
    Aging Clin Exp Res 22:412-8. 2010
  4. pmc Age at birth of first child and coronary heart disease risk factors at age 53 years in men and women: British birth cohort study
    R Hardy
    Medical Research Council Unit for Lifelong Health and Ageing, 33 Bedford Place, London, WC1B 5JU, UK
    J Epidemiol Community Health 63:99-105. 2009
  5. pmc Life course variations in the associations between FTO and MC4R gene variants and body size
    Rebecca Hardy
    MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, 33 Bedford Place, London, UK
    Hum Mol Genet 19:545-52. 2010
  6. ncbi request reprint Birthweight and blood pressure in five European birth cohort studies: an investigation of confounding factors
    Rebecca Hardy
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
    Eur J Public Health 16:21-30. 2006
  7. ncbi request reprint Commentary: BMI and mortality in the elderly--a life course perspective
    Rebecca Hardy
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 1 19 Torrington Place, London WC1E 6BT, UK
    Int J Epidemiol 35:179-80. 2006
  8. pmc Body mass index trajectories and age at menopause in a British birth cohort
    Rebecca Hardy
    Medical Research Council Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
    Maturitas 59:304-14. 2008
  9. ncbi request reprint Age at puberty and adult blood pressure and body size in a British birth cohort study
    Rebecca Hardy
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
    J Hypertens 24:59-66. 2006
  10. pmc Area deprivation across the life course and physical capability in midlife: findings from the 1946 British Birth cohort
    Emily T Murray
    MRC Unit for Lifelong Health and Ageing, University College and Royal Free Medical School, 33 Bedford Place, London WC1B 5JU, United Kingdom
    Am J Epidemiol 178:441-50. 2013

Detail Information

Publications89

  1. pmc Childhood cognitive ability and adult mental health in the British 1946 birth cohort
    Stephani L Hatch
    Columbia University, New York, NY, USA
    Soc Sci Med 64:2285-96. 2007
    ..In addition, the underlying mechanisms responsible for the gender-specific link between childhood cognitive ability and the risk of experiencing internalising disorders in mid-adulthood warrants further consideration...
  2. pmc Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme
    Rebecca Hardy
    Medical Research Council Unit for Lifelong Health and Ageing and Institute of Epidemiology and Health Care, University College London, London, United Kingdom
    PLoS ONE 8:e56483. 2013
    ..To investigate the associations of body mass index (BMI) and grip strength with objective measures of physical performance (chair rise time, walking speed and balance) including an assessment of sex differences and non-linearity...
  3. pmc Is chair rise performance a useful measure of leg power?
    Rebecca Hardy
    MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, UK
    Aging Clin Exp Res 22:412-8. 2010
    ..We assessed the relationship of chair rise performance with leg extensor power (LEP), measured using the Nottingham Power Rig (NPR), and with standing balance performance...
  4. pmc Age at birth of first child and coronary heart disease risk factors at age 53 years in men and women: British birth cohort study
    R Hardy
    Medical Research Council Unit for Lifelong Health and Ageing, 33 Bedford Place, London, WC1B 5JU, UK
    J Epidemiol Community Health 63:99-105. 2009
    ..To investigate whether the associations are explained by childhood predictors of age at parenthood or adult lifestyle factors related to child rearing...
  5. pmc Life course variations in the associations between FTO and MC4R gene variants and body size
    Rebecca Hardy
    MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, 33 Bedford Place, London, UK
    Hum Mol Genet 19:545-52. 2010
    ..Studies of the aetiology of obesity spanning different age groups may identify age-specific determinants of weight gain...
  6. ncbi request reprint Birthweight and blood pressure in five European birth cohort studies: an investigation of confounding factors
    Rebecca Hardy
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
    Eur J Public Health 16:21-30. 2006
    ..This study investigates the impact of potential confounding variables on the birthweight-blood pressure association in birth cohort studies from different time periods and geographical locations in Europe...
  7. ncbi request reprint Commentary: BMI and mortality in the elderly--a life course perspective
    Rebecca Hardy
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 1 19 Torrington Place, London WC1E 6BT, UK
    Int J Epidemiol 35:179-80. 2006
  8. pmc Body mass index trajectories and age at menopause in a British birth cohort
    Rebecca Hardy
    Medical Research Council Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
    Maturitas 59:304-14. 2008
    ..This study investigates the influence of body mass index (BMI) at ages 15, 20, 26, 36, and 43, and of BMI trajectories from 20 to 36 years on the timing of menopause and hormone therapy (HT) use until age 57 years...
  9. ncbi request reprint Age at puberty and adult blood pressure and body size in a British birth cohort study
    Rebecca Hardy
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
    J Hypertens 24:59-66. 2006
    ..To investigate the association between age at puberty and blood pressure at age 53 years...
  10. pmc Area deprivation across the life course and physical capability in midlife: findings from the 1946 British Birth cohort
    Emily T Murray
    MRC Unit for Lifelong Health and Ageing, University College and Royal Free Medical School, 33 Bedford Place, London WC1B 5JU, United Kingdom
    Am J Epidemiol 178:441-50. 2013
    ..1%, 95% CI: -8.7, -1.6). Interventions aimed at reducing midlife disparities in physical capability should target the socioeconomic environment of individuals-for standing balance, as early as childhood. ..
  11. pmc Low birth weight, later renal function, and the roles of adulthood blood pressure, diabetes, and obesity in a British birth cohort
    Richard J Silverwood
    Department of Non communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Kidney Int 84:1262-70. 2013
    ..Thus, our findings highlight the role of lower birth weight in renal disease and suggest that in those born with lower birth weight particular emphasis should be placed on avoiding becoming overweight. ..
  12. pmc Do childhood cognitive ability or smoking behaviour explain the influence of lifetime socio-economic conditions on premature adult mortality in a British post war birth cohort?
    Diana Kuh
    MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 33 Bedford Place, London WC1B 5JU, United Kingdom
    Soc Sci Med 68:1565-73. 2009
    ..These findings were similar for cardiovascular and cancer mortality...
  13. ncbi request reprint Developmental origins of midlife physical performance: evidence from a British birth cohort
    Diana Kuh
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, UK
    Am J Epidemiol 164:110-21. 2006
    ..This study is the first to show that childhood growth and development affect midlife performance; prevention of disability and frailty in later life may need to start early...
  14. ncbi request reprint Developmental origins of midlife grip strength: findings from a birth cohort study
    Diana Kuh
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
    J Gerontol A Biol Sci Med Sci 61:702-6. 2006
    ..We tested whether prepubertal growth, pubertal growth, or the development of motor and cognitive capabilities was associated with midlife muscle strength independently of other determinants of grip strength...
  15. pmc Lifetime cognitive performance is associated with midlife physical performance in a prospective national birth cohort study
    Diana Kuh
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, United Kingdom
    Psychosom Med 71:38-48. 2009
    ..To examine whether measures of cognitive performance across life are related to physical performance at age 53 years, allowing for potential confounders...
  16. pmc Life course trajectories of systolic blood pressure using longitudinal data from eight UK cohorts
    Andrew K Wills
    Medical Research Council Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, London, United Kingdom
    PLoS Med 8:e1000440. 2011
    ....
  17. ncbi request reprint Childhood cognitive ability and age at menopause: evidence from two cohort studies
    Diana Kuh
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London
    Menopause 12:475-82. 2005
    ..To investigate whether poorer cognitive ability in childhood is associated with an earlier menopause...
  18. pmc Social circumstances and education: life course origins of social inequalities in metabolic risk in a prospective national birth cohort
    Claudia Langenberg
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, England, United Kingdom
    Am J Public Health 96:2216-21. 2006
    ..We investigated the relative importance of education and childhood and adult social class in the risk of metabolic syndrome...
  19. pmc Body mass index and height from infancy to adulthood and carotid intima-media thickness at 60 to 64 years in the 1946 British Birth Cohort Study
    William Johnson
    From the MRC Unit for Lifelong Health and Ageing at UCL W J, D K, V T, R H and National Centre for Cardiovascular Prevention and Outcomes, Institute of Cardiovascular Science M C, J W, J E D, University College London, London, United Kingdom Population Health Research Centre, Division of Population Health Sciences and Education, St George s University of London, London, United Kingdom P W and International Centre for Circulatory Health, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom A D H
    Arterioscler Thromb Vasc Biol 34:654-60. 2014
    ..Atherosclerosis begins early in life and obesity is a key determinant. We investigated the role of body mass index (BMI) and height from infancy to adulthood in presenting with high adulthood carotid intima-media thickness...
  20. pmc Lifetime socioeconomic inequalities in physical and cognitive aging
    Louise Hurst
    Department of Epidemiology and Public Health, University College London, London, UK
    Am J Public Health 103:1641-8. 2013
    ..We examined the relationship between childhood and adult socioeconomic position (SEP) and objectively assessed, later-life functioning...
  21. pmc Early-life overweight trajectory and CKD in the 1946 British birth cohort study
    Richard J Silverwood
    Department of Non communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Kidney Dis 62:276-84. 2013
    ..Few studies have examined the impact of childhood obesity on later kidney disease, and consequently, our understanding is very limited...
  22. pmc Age and gender differences in physical capability levels from mid-life onwards: the harmonisation and meta-analysis of data from eight UK cohort studies
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, London, United Kingdom
    PLoS ONE 6:e27899. 2011
    ..These harmonised data are now being used within HALCyon to understand the lifetime social and biological determinants of physical capability and its changes with age...
  23. pmc Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study
    Andrew K Wills
    MRC Unit for Lifelong Health and Ageing, University College London, 33 Bedford Place, London WC1B 5JU, UK
    Ann Rheum Dis 71:655-60. 2012
    ....
  24. pmc Population heterogeneity in trajectories of midlife blood pressure
    Andrew K Wills
    MRC Unit for Lifelong Health and Ageing, University College London, London, UK
    Epidemiology 23:203-11. 2012
    ..We investigated whether there are subgroups with different underlying (latent) trajectories of midlife systolic blood pressure (BP), diastolic BP, and pulse pressure in a UK cohort...
  25. ncbi request reprint Long-term effects of breast-feeding in a national birth cohort: educational attainment and midlife cognitive function
    Marcus Richards
    MRC National Survey of Health and Development, Royal Free and University College Medical School, University College London, Department of Epidemiology and Public Health, 1 19 Torrington Place, UK
    Public Health Nutr 5:631-5. 2002
    ..Little is known, however, about possible longer-term effects of breast-feeding. We investigated the effect of breast-feeding on educational attainment, and on a range of cognitive skills in midlife, in the British 1946 birth cohort...
  26. ncbi request reprint Birthweight, childhood growth, and blood pressure at 43 years in a British birth cohort
    Rebecca Hardy
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
    Int J Epidemiol 33:121-9. 2004
    ..Low birthweight is associated with high blood pressure in later life, but it is unclear whether the association is confounded with or modified by maternal and socioeconomic factors or childhood growth...
  27. ncbi request reprint Birthweight, childhood social class, and change in adult blood pressure in the 1946 British birth cohort
    Rebecca Hardy
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, WC1E 6BT, London, UK
    Lancet 362:1178-83. 2003
    ..The negative effect of birthweight on systolic blood pressure has been suggested to be initiated in utero and amplified with age. We aimed to investigate this hypothesis...
  28. pmc Life course models of socioeconomic position and cardiovascular risk factors: 1946 birth cohort
    Emily T Murray
    MRC Unit for Lifelong Health and Ageing, University College and Royal Free Medical School, London, United Kingdom
    Ann Epidemiol 21:589-97. 2011
    ....
  29. pmc Cessation of hormone replacement therapy after reports of adverse findings from randomized controlled trials: evidence from a British Birth Cohort
    Gita Mishra
    National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, England
    Am J Public Health 96:1219-25. 2006
    ....
  30. ncbi request reprint Growth from birth to adulthood and bone phenotype in early old age: a British birth cohort study
    Diana Kuh
    Medical Research Council MRC Unit for Lifelong Health and Ageing, Institute of Epidemiology and Health Care, University College London, London, UK
    J Bone Miner Res 29:123-33. 2014
    ....
  31. ncbi request reprint Birth weight, childhood size, and muscle strength in adult life: evidence from a birth cohort study
    Diana Kuh
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, England
    Am J Epidemiol 156:627-33. 2002
    ..As the inevitable loss of muscle fibers proceeds in old age, a deficit in the number of fibers could threaten quality of life and independence...
  32. pmc Childhood stunting and mortality between 36 and 64 years: the British 1946 Birth Cohort Study
    Ken K Ong
    Medical Research Council Unit for Lifelong Health and Ageing, London WC1B 5JU, United Kingdom
    J Clin Endocrinol Metab 98:2070-7. 2013
    ..Our aim was to examine the associations between childhood or adult height and adult mortality...
  33. pmc Role of lifetime body mass index in the association between age at puberty and adult lipids: findings from men and women in a British birth cohort
    Mary B Pierce
    MRC Unit for Lifelong Health and Ageing, London, United Kingdom
    Ann Epidemiol 20:676-82. 2010
    ..The relationship between puberty and lipids is unclear. Our aim was to assess whether age at puberty was associated with triglyceride and total low-density lipoprotein and high-density lipoprotein cholesterol at age 53 years...
  34. ncbi request reprint Hysterectomy and subsequent psychological health: findings from a British birth cohort study
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing, 33 Bedford Place, London, WC1B 5JU, UK
    J Affect Disord 115:122-30. 2009
    ..We aimed to test the association between hysterectomy and subsequent psychological health and examine variation in this association by characteristics of hysterectomy...
  35. pmc Lifelong socioeconomic position and physical performance in midlife: results from the British 1946 birth cohort
    Bjørn Heine Strand
    MRC National Survey of Health and Development, MRC Unit for Lifelong Health and Ageing, London, UK
    Eur J Epidemiol 26:475-83. 2011
    ..In contrast, the associations of own education and adult occupation with physical performance were generally not maintained after adjustment. SEP across life impacts on midlife physical performance, and thereby the ageing process...
  36. ncbi request reprint Socio-economic position across the life course and hysterectomy in three British cohorts: a cross-cohort comparative study
    Rachel Cooper
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, University College London, UK
    BJOG 112:1126-33. 2005
    ..To examine the association between indicators of lifetime socio-economic position and rates of hysterectomy in three British cohorts...
  37. pmc Gender and life course occupational social class differences in trajectories of functional limitations in midlife: findings from the 1946 British birth cohort
    Emily T Murray
    MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, UK
    J Gerontol A Biol Sci Med Sci 66:1350-9. 2011
    ....
  38. pmc Physical capability and subsequent positive mental wellbeing in older people: findings from five HALCyon cohorts
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing, University College London, 33 Bedford Place, London, WC1B 5JU, UK
    Age (Dordr) 36:445-56. 2014
    ....
  39. pmc No association between gain in body mass index across the life course and midlife cognitive function and cognitive reserve--the 1946 British Birth Cohort study
    Emiliano Albanese
    MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
    Alzheimers Dement 8:470-82. 2012
    ..The association between lifelong body mass index (BMI) and cognitive function has not been comprehensively studied...
  40. pmc Childhood social class and adult adiposity and blood-pressure trajectories 36-53 years: gender-specific results from a British birth cohort
    Bjørn Heine Strand
    MRC National Survey of Healthand Development, MRC Unit for Lifelong Health and Ageing, London, UK
    J Epidemiol Community Health 66:512-8. 2012
    ..In this study, the authors investigate gender-specific effects of childhood socio-economic position (SEP) on adiposity and blood pressure at three time points in adulthood...
  41. pmc Childhood, adolescent and early adult body mass index in relation to adult mortality: results from the British 1946 birth cohort
    Bjørn Heine Strand
    MRC National Survey of Health and Development, MRC Unit for Lifelong Health and Ageing, London, UK
    J Epidemiol Community Health 66:225-32. 2012
    ..The aim is to investigate the impact of childhood, adolescent and early adult BMI on premature adult all-cause mortality...
  42. pmc Objective measures of physical capability and subsequent health: a systematic review
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, London, UK
    Age Ageing 40:14-23. 2011
    ....
  43. pmc Timing of menarche, childbearing and hysterectomy risk
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing, London, UK
    Maturitas 61:317-22. 2008
    ....
  44. ncbi request reprint Influence of short stature on the change in pulse pressure, systolic and diastolic blood pressure from age 36 to 53 years: an analysis using multilevel models
    Claudia Langenberg
    Department of Epidemiology and Public Health, University College London Medical School, 1 19 Torrington Place, London WC1E 6BT, UK
    Int J Epidemiol 34:905-13. 2005
    ..It is unclear how these adult measures of childhood growth influence the change in blood pressure as it increases with age...
  45. pmc Mortality in adults aged 26-54 years related to socioeconomic conditions in childhood and adulthood: post war birth cohort study
    Diana Kuh
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London, London WC1E 6BT
    BMJ 325:1076-80. 2002
    ..To examine premature mortality in adults in relation to socioeconomic conditions in childhood and adulthood...
  46. ncbi request reprint Does active leisure protect cognition? Evidence from a national birth cohort
    Marcus Richards
    Department of Epidemiology and Public Health, University College London, MRC National Survey of Health and Development, 1 19 Torrington Place, London WC1E 6BT, UK
    Soc Sci Med 56:785-92. 2003
    ..We conclude that physical exercise and spare-time activity are significantly associated with benefit to memory in midlife, although these two kinds of voluntary activity may exert their effects on cognition via different paths...
  47. pmc Cognitive and kidney function: results from a british birth cohort reaching retirement age
    Richard J Silverwood
    Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 9:e86743. 2014
    ..We aimed to explore possible explanations for this association in the Medical Research Council National Survey of Health and Development, a prospective birth cohort representative of the general British population...
  48. pmc A structured approach to modelling the effects of binary exposure variables over the life course
    Gita Mishra
    MRC Unit for Lifelong Health and Ageing, University College and Royal Free Medical School, London, UK
    Int J Epidemiol 38:528-37. 2009
    ..This article highlights potential issues in the interpretation of results obtained from such an approach...
  49. pmc Child-to-adult body mass index and height trajectories: a comparison of 2 British birth cohorts
    Leah Li
    Centre for Paediatric Epidemiology and Biostatistics Medical Research Council Centre of Epidemiology for Child Health, Institute of Child Health, University College London, 30 Guilford Street, London WC1N1EH, United Kingdom
    Am J Epidemiol 168:1008-15. 2008
    ..1% vs. 10.8% in males and 23.7% vs. 14.8% in females). Changes in height and adiposity over a relatively short period of 12 years suggest the likelihood of opposing trends of influences on later disease risk in these populations...
  50. pmc Association between adolescent emotional problems and metabolic syndrome: the modifying effect of C-reactive protein gene (CRP) polymorphisms
    Darya Gaysina
    MRC Unit for Lifelong Health and Ageing, University College London, London, UK
    Brain Behav Immun 25:750-8. 2011
    ..These findings may highlight new ways of identifying people with emotional problems at high risk of developing the metabolic syndrome, which is of great importance for the management of the physical health of these patients...
  51. ncbi request reprint Are the effects of risk factors for timing of menopause modified by age? Results from a British birth cohort study
    Gita Mishra
    Medical Research Council National Survey of Health and Development, University College and Royal Free Medical School, London, UK
    Menopause 14:717-24. 2007
    ..This study investigated the influence of mother's age at menopause, early life and adult behavioral factors on the timing of menopause until age 57 years, and whether these effects vary according to the women's age at menopause...
  52. ncbi request reprint Grip strength, postural control, and functional leg power in a representative cohort of British men and women: associations with physical activity, health status, and socioeconomic conditions
    Diana Kuh
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 1 19 Torrington Place, London, United Kingdom, WC1E 6BT
    J Gerontol A Biol Sci Med Sci 60:224-31. 2005
    ....
  53. pmc Life course social roles and women's health in mid-life: causation or selection?
    Anne McMunn
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    J Epidemiol Community Health 60:484-9. 2006
    ....
  54. pmc Clinical disorders in a post war British cohort reaching retirement: evidence from the First National Birth Cohort study
    Mary B Pierce
    MRC Unit for Lifelong Health and Ageing, London, England
    PLoS ONE 7:e44857. 2012
    ..This study describes the distribution and clustering of 15 common clinical disorders requiring medical treatment or supervision in a representative British cohort approaching retirement, and how health tracked across adulthood...
  55. ncbi request reprint Alcohol consumption and midlife cognitive change in the British 1946 birth cohort study
    Marcus Richards
    MRC National Survey of Health and Development, University College London, Department of Epidemiology and Public Health, London WC1E 6BT, UK
    Alcohol Alcohol 40:112-7. 2005
    ..However, more longitudinal studies are required to confirm that alcohol has an effect on cognitive change and to rule out the possibility that those of higher ability engage in a lifestyle that protects against cognitive decline...
  56. ncbi request reprint Influence of height, leg and trunk length on pulse pressure, systolic and diastolic blood pressure
    Claudia Langenberg
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, 1 19 Torrington Place, London WC1 6BT, UK
    J Hypertens 21:537-43. 2003
    ..To compare the effects of height, leg and trunk length on pulse pressure (PP), systolic (SBP) and diastolic blood pressure (DBP) in men and women...
  57. ncbi request reprint Cohort Profile: The 1946 National Birth Cohort (MRC National Survey of Health and Development)
    Michael Wadsworth
    MRC National Survey of Health and Development, Royal Free and UCL Medical School, Department of Epidemiology and Public Health, 1 19 Torrington Place, London WC1E 6BT, UK
    Int J Epidemiol 35:49-54. 2006
  58. pmc Is there an association between hysterectomy and subsequent adiposity?
    Rachel Cooper
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, UK
    Maturitas 58:296-307. 2007
    ....
  59. ncbi request reprint Women's health in midlife: findings from a British birth cohort study
    Diana Kuh
    MRC Research Scientist and Reader, Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
    J Br Menopause Soc 9:55-60. 2003
    ..Of particular interest are their results linking ovarian ageing to developmental factors. Replication of these findings in other life course cohorts is being sought...
  60. ncbi request reprint Social and environmental conditions across the life course and age at menopause in a British birth cohort study
    Rebecca Hardy
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London WC1E 6BT, UK
    BJOG 112:346-54. 2005
    ..To assess whether socio-economic status, environmental stress and hardship throughout the life course are associated with age at menopause...
  61. ncbi request reprint Childhood cognitive ability and deaths up until middle age: a post-war birth cohort study
    Diana Kuh
    Department of Epidemiology and Public Health, Royal Free and University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Int J Epidemiol 33:408-13. 2004
    ..We examined mortality in relation to cognitive ability at age 8 years in a birth cohort and investigated these possible reasons...
  62. pmc The bidirectional association between depressive symptoms and gait speed: evidence from the English Longitudinal Study of Ageing (ELSA)
    Panayotes Demakakos
    Department of Epidemiology and Public Health, University College London, London, United Kingdom
    PLoS ONE 8:e68632. 2013
    ..We examined whether the association between depressive symptoms and physical performance measured using gait speed is bidirectional...
  63. pmc MUC5AC and inflammatory mediators associated with respiratory outcomes in the British 1946 birth cohort
    Lauren Johnson
    Research Department of Genetics, Evolution and Environment, University College London Darwin Building, London, UK
    Respirology 18:1003-10. 2013
    ..The aim of this study was to examine the effect of genetic variation on susceptibility to common respiratory conditions...
  64. pmc Association between younger age when first overweight and increased risk for CKD
    Richard J Silverwood
    Department of Non communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, United Kingdom
    J Am Soc Nephrol 24:813-21. 2013
    ..Taken together, these results suggest that preventing overweight in early adulthood may have a considerable effect on the prevalence of CKD in the population...
  65. pmc Challenges in examining area effects across the life course on physical capability in mid-life: findings from the 1946 British Birth Cohort
    Emily T Murray
    MRC Unit for Lifelong Health and Ageing, University College and Royal Free Medical School, 33 Bedford Place, London WC1B 5JU, UK
    Health Place 18:366-74. 2012
    ....
  66. ncbi request reprint Lung function and cognitive ability in a longitudinal birth cohort study
    Marcus Richards
    MRC National Survey of Health and Development, University College London, UK
    Psychosom Med 67:602-8. 2005
    ..The objective of this study was to examine the association between forced expiratory volume in 1 second (FEV1) and cognitive ability in midlife in the normal population...
  67. ncbi request reprint Statistical issues in life course epidemiology
    Bianca L de Stavola
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Epidemiol 163:84-96. 2006
    ..Examples from two cohorts in the United Kingdom are used to illustrate alternative modeling strategies. The authors conclude that more than one analytical approach should be adopted to gain more insight into the underlying mechanisms...
  68. ncbi request reprint Birthweight, postnatal growth and cognitive function in a national UK birth cohort
    Marcus Richards
    MRC National Survey of Health and Development, University College London, UK
    Int J Epidemiol 31:342-8. 2002
    ..We therefore investigated the independent effects of birthweight and postnatal height adjusted for postnatal weight on cognitive function and educational attainment while controlling for family background...
  69. ncbi request reprint The relationship between Sense of Coherence and toothbrushing behaviours in Iranian adolescents in Mashhad
    Mojtaba Dorri
    Department of Epidemiology and Public Health, University College London, London, UK
    J Clin Periodontol 37:46-52. 2010
    ..The aim of this study was to assess the association between Sense of Coherence (SOC) and toothbrushing behaviours in Iranian adolescents in Mashhad...
  70. ncbi request reprint Commentary: The association between height growth and cholesterol levels during puberty: implications for adult health
    Rebecca Hardy
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, 1 19 Torrington Place, London WC1E 6BT, UK
    Int J Epidemiol 32:1110-1. 2003
  71. ncbi request reprint Lifetime risk factors for women's psychological distress in midlife
    Diana Kuh
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, Gower Street Campus, 1 19 Torrington Place, London WC1E 6BT, UK
    Soc Sci Med 55:1957-73. 2002
    ..More attention to a long term temporal perspective is warranted in research on the causes of psychological distress in women at midlife...
  72. pmc Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration
    Aspasia Angelakopoulou
    Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Eur Heart J 33:393-407. 2012
    ....
  73. ncbi request reprint Change in psychological and vasomotor symptom reporting during the menopause
    Rebecca Hardy
    Department of Epidemiology and Public Health, Royal Free and University College Medical School, Medical Research Council National Survey of Health and Development, Gower Street Campus, 1 19 Torrington Place, London WC1E 6BT, UK
    Soc Sci Med 55:1975-88. 2002
    ..Factors other than the menopause should be considered, such as concurrent life events and past experiences and behaviours, when considering the treatment of psychological symptoms in women during middle life...
  74. ncbi request reprint Relationship between birthweight and blood lipid concentrations in later life: evidence from the existing literature
    Liisa Lauren
    Department of Epidemiology and Public Health, Imperial College London, Faculty of Medicine, Norfolk Place, London W2 1PG, UK
    Int J Epidemiol 32:862-76. 2003
    ....
  75. ncbi request reprint Mothers' sense of coherence and their adolescent children's oral health status and behaviours
    MariadoCarmoMatias Freire
    Department of Epidemiology and Public Health, The Royal Free and University College Medical School, University College London, UK
    Community Dent Health 19:24-31. 2002
    ..To investigate the relationship between mothers' sense of coherence (SOC) and their adolescent children's oral health. SOC is the central construct of the salutogenesis model of health, which seeks to explain factors that promote health...
  76. pmc Objectively measured physical capability levels and mortality: systematic review and meta-analysis
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing and Division of Population Health, University College London, London WC1B 5JU
    BMJ 341:c4467. 2010
    ....
  77. ncbi request reprint A life-course approach to assess the relationship between social and psychological circumstances and gingival status in adolescents
    Belinda Nicolau
    Department of Epidemiology and Public Health, Royal Free and University College, London Medical School, London WC1E 6BT, UK
    J Clin Periodontol 30:1038-45. 2003
    ..Several models have been proposed to explain the causes of periodontal diseases. None have adopted the life-course approach...
  78. pmc Depressive symptoms and risk of type 2 diabetes in a national sample of middle-aged and older adults: the English longitudinal study of aging
    Panayotes Demakakos
    Department of Epidemiology and Public Health, University College London, London, UK
    Diabetes Care 33:792-7. 2010
    ..To examine the association between baseline elevated depressive symptoms and incident type 2 diabetes in a national sample of people aged > or =50 years...
  79. doi request reprint Four-year follow-up of a randomized controlled trial of a social support intervention on infant feeding practices
    Anja Scheiwe
    Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK
    Matern Child Nutr 6:328-37. 2010
    ..57; 95% confidence interval (CI) 0.99, 2.49] and were more likely to never drink squash (RR = 1.76; 95% CI 1.20, 2.58). The data suggest that the original peer support intervention had a small number of positive long-term effects...
  80. ncbi request reprint Major elective joint replacement surgery: socioeconomic variations in surgical risk, postoperative morbidity and length of stay
    Jennifer Hollowell
    Department of Epidemiology and Public Health, University College London, London, UK
    J Eval Clin Pract 16:529-38. 2010
    ..Our aim was to examine associations between deprivation and aspects of the inpatient episode for patients undergoing these procedures...
  81. pmc Blood pressure loci identified with a gene-centric array
    Toby Johnson
    Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK
    Am J Hum Genet 89:688-700. 2011
    ....
  82. ncbi request reprint Prenatal factors, childhood growth trajectories and age at menarche
    Isabel dos Santos Silva
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Int J Epidemiol 31:405-12. 2002
    ..The mechanisms underlying this association are not clear, however, as birthweight is a predictor of body size in childhood, and a large body size is known to be associated with an early onset of menarche...
  83. ncbi request reprint Clinical, social and psychosocial factors associated with self-rated oral health in Brazilian adolescents
    Marcos P Pattussi
    Programa de Pós Graduação em Saúde Coletiva, Universidade do Vale do Rio dos Sinos, Sao Leopoldo, RS, Brazil
    Community Dent Oral Epidemiol 35:377-86. 2007
    ..The objective of this study is to investigate the main social, psychosocial and clinical factors associated with poor self-rated oral health in adolescents...
  84. ncbi request reprint Impacts of dental pain on daily activities of adolescents aged 14-15 years and their families
    Paulo S A Goes
    Departamento de Odontologia Social, Faculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Recife PE, Brazil
    Acta Odontol Scand 66:7-12. 2008
    ..To assess the prevalence and severity of dental pain on the daily lives of adolescents and their families in Brazil, and, in terms of socio-economic status, whether there are differences in the prevalence of impacts...
  85. ncbi request reprint Women's body satisfaction at midlife and lifetime body size: a prospective study
    Lindsay McLaren
    Department of Community Health Sciences, University of Calgary, Alberta, Canada
    Health Psychol 22:370-7. 2003
    ..Attention to these factors across the life span is necessary to understand body dissatisfaction in women at midlife...
  86. pmc Neighborhood social capital and dental injuries in Brazilian adolescents
    Marcos Pascoal Pattussi
    Postgraduate Program on Collective Health of the Universidade do Vale do Rio dos Sinos, Sao Leopoldo, Brazil
    Am J Public Health 96:1462-8. 2006
    ..We investigated the association between social capital and dental injury...
  87. ncbi request reprint Patterns of interphalangeal hand joint involvement of osteoarthritis among men and women: a British cohort study
    Jason Poole
    Southampton General Hospital, University of Southampton, Southampton, UK
    Arthritis Rheum 48:3371-6. 2003
    ..To characterize the pattern of involvement of osteoarthritis (OA) of the hand among men and women of the same age...
  88. ncbi request reprint The potential impact of neighborhood empowerment on dental caries among adolescents
    Marcos P Pattussi
    Programa de Pós Graduação em Saúde Coletiva, Universidade do Vale do Rio dos Sinos São Leopoldo RS, Brazil
    Community Dent Oral Epidemiol 34:344-50. 2006
    ..This relationship has not been explored in relation to dental health. The objective of this study was to investigate the association between neighborhood empowerment and dental caries in adolescents...
  89. ncbi request reprint Postnatal depression and the original mother-child relationship: a prospective cohort study
    Lindsay McLaren
    Department of Community Health Sciences, University of Calgary, 3330 Hospital Dr NW, Calgary, AB, Canada T2N 4N1
    J Affect Disord 100:211-9. 2007
    ..Previous studies assessing the role of early mother-child relationship as a risk factor for postnatal depression have been cross-sectional and/or retrospective in nature...