P H Francis-West

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi BMP/GDF-signalling interactions during synovial joint development
    P H Francis-West
    Department of Craniofacial Development, King s College London, Guy s Tower, Floor 28, London Bridge, SE1 9RT, UK
    Cell Tissue Res 296:111-9. 1999
  2. ncbi Mechanisms of GDF-5 action during skeletal development
    P H Francis-West
    Department of Craniofacial Development, Guy s, King s and St Thomas School of Dentistry, Guy s Tower, Floor 28, London Bridge, London, SE1 9RT, UK
    Development 126:1305-15. 1999
  3. ncbi Cloning and expression of the Wnt antagonists Sfrp-2 and Frzb during chick development
    R K Ladher
    Department of Craniofacial Development, Guy s, King s and St Thomas School of Dentistry, Guy s Tower, Floor 27, Guy s Hospital, London, SE1 9RT, United Kingdom
    Dev Biol 218:183-98. 2000
  4. ncbi Identification of synergistic signals initiating inner ear development
    R K Ladher
    Department of Craniofacial Development, King s College, London, SE1 9RT, UK
    Science 290:1965-7. 2000
  5. ncbi Misexpression of noggin leads to septal defects in the outflow tract of the chick heart
    S P Allen
    Department of Craniofacial Development, Guy s, King s and St Thomas School of Dentistry, Guy s Tower, Floor 28, London Bridge, London, SE1 9RT, United Kingdom
    Dev Biol 235:98-109. 2001
  6. ncbi Craniofacial development: the tissue and molecular interactions that control development of the head
    P H Francis-West
    Department of Craniofacial Development King s College, London, SE1 9RT, UK
    Adv Anat Embryol Cell Biol 169:III-VI, 1-138. 2003
  7. ncbi Expression of genes encoding bone morphogenetic proteins and sonic hedgehog in talpid (ta3) limb buds: their relationships in the signalling cascade involved in limb patterning
    P H Francis-West
    Department of Anatomy and Developmental Biology, University College of London, United Kingdom
    Dev Dyn 203:187-97. 1995
  8. ncbi Expression of chick Barx-1 and its differential regulation by FGF-8 and BMP signaling in the maxillary primordia
    A J Barlow
    Department of Craniofacial Development, Guy s, King s, and St Thomas School of Dentistry, Guy s Hospital, London, United Kingdom
    Dev Dyn 214:291-302. 1999
  9. ncbi Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation
    E Kavanagh
    Department of Veterinary Basic Sciences, The Royal Veterinary College, London, UK
    Dev Dyn 235:826-34. 2006
  10. ncbi Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development
    D J Phippard
    Institute of Cancer Research, Haddow Laboratories, Sutton, Surrey, UK
    Development 122:2729-37. 1996

Collaborators

Detail Information

Publications10

  1. ncbi BMP/GDF-signalling interactions during synovial joint development
    P H Francis-West
    Department of Craniofacial Development, King s College London, Guy s Tower, Floor 28, London Bridge, SE1 9RT, UK
    Cell Tissue Res 296:111-9. 1999
    ..Finally, we discuss possible mechanisms of how a joint forms and the evidence that the joint is a 'signalling centre' that may coordinate the development of adjacent skeletal structures...
  2. ncbi Mechanisms of GDF-5 action during skeletal development
    P H Francis-West
    Department of Craniofacial Development, Guy s, King s and St Thomas School of Dentistry, Guy s Tower, Floor 28, London Bridge, London, SE1 9RT, UK
    Development 126:1305-15. 1999
    ....
  3. ncbi Cloning and expression of the Wnt antagonists Sfrp-2 and Frzb during chick development
    R K Ladher
    Department of Craniofacial Development, Guy s, King s and St Thomas School of Dentistry, Guy s Tower, Floor 27, Guy s Hospital, London, SE1 9RT, United Kingdom
    Dev Biol 218:183-98. 2000
    ..Finally, we have used the early Xenopus embryo as an in vivo assay to show that Sfrp-2, like Frzb, is a Wnt antagonist. These results suggest that Sfrp-2 and Frzb may function in the developing embryo by modulating Wnt signalling...
  4. ncbi Identification of synergistic signals initiating inner ear development
    R K Ladher
    Department of Craniofacial Development, King s College, London, SE1 9RT, UK
    Science 290:1965-7. 2000
    ..Furthermore, we demonstrate the synergistic interactions of the extracellular polypeptide ligands FGF-19 and Wnt-8c as mediators of mesodermal and neural signals, respectively, initiating inner ear development...
  5. ncbi Misexpression of noggin leads to septal defects in the outflow tract of the chick heart
    S P Allen
    Department of Craniofacial Development, Guy s, King s and St Thomas School of Dentistry, Guy s Tower, Floor 28, London Bridge, London, SE1 9RT, United Kingdom
    Dev Biol 235:98-109. 2001
    ..These results suggest that BMP-2/4 function may mediate several key events during cardiac development...
  6. ncbi Craniofacial development: the tissue and molecular interactions that control development of the head
    P H Francis-West
    Department of Craniofacial Development King s College, London, SE1 9RT, UK
    Adv Anat Embryol Cell Biol 169:III-VI, 1-138. 2003
    ..Our current knowledge of the genes responsible for these human syndromes together with how the head develops, is rapidly advancing so that we will soon understand the complex set of molecular and tissue interactions that build a head...
  7. ncbi Expression of genes encoding bone morphogenetic proteins and sonic hedgehog in talpid (ta3) limb buds: their relationships in the signalling cascade involved in limb patterning
    P H Francis-West
    Department of Anatomy and Developmental Biology, University College of London, United Kingdom
    Dev Dyn 203:187-97. 1995
    ..In addition, the dissociation between the expression of shh and Bmps suggests distinct roles for the encoded molecules in signalling and response in a-p patterning of limb buds...
  8. ncbi Expression of chick Barx-1 and its differential regulation by FGF-8 and BMP signaling in the maxillary primordia
    A J Barlow
    Department of Craniofacial Development, Guy s, King s, and St Thomas School of Dentistry, Guy s Hospital, London, United Kingdom
    Dev Dyn 214:291-302. 1999
    ..This provides evidence that the differential expression of FGF-8 and BMPs may determine homeobox-containing gene expression and hence patterning of the facial primordia...
  9. ncbi Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation
    E Kavanagh
    Department of Veterinary Basic Sciences, The Royal Veterinary College, London, UK
    Dev Dyn 235:826-34. 2006
    ..These findings support a direct mechano-dependent role for FGF-2, but not FGF-4, in the cavitation process and indicate that GDF-5 is likely to influence chondrogenesis positively without contributing directly to joint cavity formation...
  10. ncbi Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development
    D J Phippard
    Institute of Cancer Research, Haddow Laboratories, Sutton, Surrey, UK
    Development 122:2729-37. 1996
    ..The regulation of Msx-2 expression by oestrogen raises the possibility that hormonal regulation of mammary development is mediated through the control of epithelial-mesenchymal interactions...