T Dubois

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi request reprint 14-3-3 is phosphorylated by casein kinase I on residue 233. Phosphorylation at this site in vivo regulates Raf/14-3-3 interaction
    T Dubois
    Division of Protein Structure, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom
    J Biol Chem 272:28882-8. 1997
  2. ncbi request reprint Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins
    T Dubois
    University of Edinburgh, Division of Biomedical and Clinical Laboratory Sciences, Hugh Robson Building, George Square, Edinburgh EH8 9XD
    J Biol Chem 276:18757-64. 2001
  3. ncbi request reprint Specificity of 14-3-3 isoform dimer interactions and phosphorylation
    A Aitken
    University of Edinburgh, Division of Biomedical and Clinical Laboratory Sciences, Hugh Robson Building, George Square, Edinburgh EH8 9XD, Scotland, UK
    Biochem Soc Trans 30:351-60. 2002

Collaborators

Detail Information

Publications3

  1. ncbi request reprint 14-3-3 is phosphorylated by casein kinase I on residue 233. Phosphorylation at this site in vivo regulates Raf/14-3-3 interaction
    T Dubois
    Division of Protein Structure, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom
    J Biol Chem 272:28882-8. 1997
    ..We have now shown that in vivo phosphorylation of 14-3-3 zeta at the CKIalpha site (Thr-233) negatively regulates its binding to c-Raf, and may be important in Raf-mediated signal transduction...
  2. ncbi request reprint Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins
    T Dubois
    University of Edinburgh, Division of Biomedical and Clinical Laboratory Sciences, Hugh Robson Building, George Square, Edinburgh EH8 9XD
    J Biol Chem 276:18757-64. 2001
    ..These proteins are involved in membrane trafficking and actin cytoskeleton rearrangement, thus supporting a role for CKIalpha in these biological events...
  3. ncbi request reprint Specificity of 14-3-3 isoform dimer interactions and phosphorylation
    A Aitken
    University of Edinburgh, Division of Biomedical and Clinical Laboratory Sciences, Hugh Robson Building, George Square, Edinburgh EH8 9XD, Scotland, UK
    Biochem Soc Trans 30:351-60. 2002
    ..A specific repertoire of dimer formation may influence which of the 14-3-3-interacting proteins could be brought together. Mammalian and yeast 14-3-3 isoforms show a preference for dimerization with specific partners in vivo...