Geoff Daniels

Summary

Affiliation: National Blood Service
Country: UK

Publications

  1. ncbi request reprint Molecular blood grouping
    G Daniels
    Bristol Institute for Transfusion Sciences, International Blood Group Reference Laboratory, Bristol, UK
    Vox Sang 87:63-6. 2004
  2. ncbi request reprint Functions of red cell surface proteins
    G Daniels
    Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Bristol, UK
    Vox Sang 93:331-40. 2007
  3. ncbi request reprint Functional aspects of red cell antigens
    G Daniels
    Bristol Institute for Transfusion Sciences, UK
    Blood Rev 13:14-35. 1999
  4. doi request reprint Fetal RhD genotyping: a more efficient use of anti-D immunoglobulin
    G Daniels
    Bristol Institute for Transfusion Sciences and International Blood Group Reference Laboratory, NHSBT, Southmead Road, Bristol, United Kingdom
    Transfus Clin Biol 14:568-71. 2007
  5. ncbi request reprint Fetal blood group genotyping: present and future
    Geoff Daniels
    International Blood Group of Reference Laboratory, National Blood Service, Southmead Road, Bristol, BS10 5ND, United Kingdom
    Ann N Y Acad Sci 1075:88-95. 2006
  6. ncbi request reprint Report of the Second International Workshop on molecular blood group genotyping
    G Daniels
    International Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, UK
    Vox Sang 93:83-8. 2007
  7. ncbi request reprint Fetal blood group genotyping from DNA from maternal plasma: an important advance in the management and prevention of haemolytic disease of the fetus and newborn
    G Daniels
    International Blood Group Reference Laboratory, Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Vox Sang 87:225-32. 2004
  8. ncbi request reprint Blood group terminology 2004: from the International Society of Blood Transfusion committee on terminology for red cell surface antigens
    G L Daniels
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Vox Sang 87:304-16. 2004
  9. ncbi request reprint Report of the First International Workshop on molecular blood group genotyping
    G Daniels
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Vox Sang 88:136-42. 2005
  10. ncbi request reprint The molecular genetics of blood group polymorphism
    Geoff Daniels
    Bristol Institute for Transfusion Sciences, National Blood Service, Southmead Road, Bristol BS10 5ND, UK
    Transpl Immunol 14:143-53. 2005

Collaborators

Detail Information

Publications56

  1. ncbi request reprint Molecular blood grouping
    G Daniels
    Bristol Institute for Transfusion Sciences, International Blood Group Reference Laboratory, Bristol, UK
    Vox Sang 87:63-6. 2004
  2. ncbi request reprint Functions of red cell surface proteins
    G Daniels
    Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Bristol, UK
    Vox Sang 93:331-40. 2007
    ....
  3. ncbi request reprint Functional aspects of red cell antigens
    G Daniels
    Bristol Institute for Transfusion Sciences, UK
    Blood Rev 13:14-35. 1999
    ..If these blood group antigens have important functions, other structures must be able to carry out those functions in their absence. Almost nothing is known of the biological significance of blood group polymorphism...
  4. doi request reprint Fetal RhD genotyping: a more efficient use of anti-D immunoglobulin
    G Daniels
    Bristol Institute for Transfusion Sciences and International Blood Group Reference Laboratory, NHSBT, Southmead Road, Bristol, United Kingdom
    Transfus Clin Biol 14:568-71. 2007
    ..The results of trials in Bristol and Amsterdam suggest that such routine testing is feasible and accurate...
  5. ncbi request reprint Fetal blood group genotyping: present and future
    Geoff Daniels
    International Blood Group of Reference Laboratory, National Blood Service, Southmead Road, Bristol, BS10 5ND, United Kingdom
    Ann N Y Acad Sci 1075:88-95. 2006
    ..Similar trials have already been reported by Sanquin Research Laboratories in Amsterdam...
  6. ncbi request reprint Report of the Second International Workshop on molecular blood group genotyping
    G Daniels
    International Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, UK
    Vox Sang 93:83-8. 2007
    ..With greater care and attention to detail, very high standards could be set for molecular blood group genotyping...
  7. ncbi request reprint Fetal blood group genotyping from DNA from maternal plasma: an important advance in the management and prevention of haemolytic disease of the fetus and newborn
    G Daniels
    International Blood Group Reference Laboratory, Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Vox Sang 87:225-32. 2004
    ..Within a few years, it is probable that fetuses of all D-negative pregnant women will be tested for RHD, to establish whether the mother requires antenatal anti-D immunoglobulin prophylaxis...
  8. ncbi request reprint Blood group terminology 2004: from the International Society of Blood Transfusion committee on terminology for red cell surface antigens
    G L Daniels
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Vox Sang 87:304-16. 2004
  9. ncbi request reprint Report of the First International Workshop on molecular blood group genotyping
    G Daniels
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Vox Sang 88:136-42. 2005
    ..Further international workshops will take place every 2 years, with a more limited exercise being organized in the intervening years...
  10. ncbi request reprint The molecular genetics of blood group polymorphism
    Geoff Daniels
    Bristol Institute for Transfusion Sciences, National Blood Service, Southmead Road, Bristol BS10 5ND, UK
    Transpl Immunol 14:143-53. 2005
    ..Other applications are being developed for the future...
  11. ncbi request reprint International Society of Blood Transfusion Committee on Terminology for Red Cell Surface Antigens: Cape Town report
    G Daniels
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Vox Sang 92:250-3. 2007
  12. ncbi request reprint The molecular basis of the Lutheran blood group antigens
    Geoff Daniels
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Vox Sang 83:189-92. 2002
  13. ncbi request reprint A century of human blood groups
    G Daniels
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Wien Klin Wochenschr 113:781-6. 2001
    ..Analysis of the development of these proteins on erythroid cells during erythropoiesis, ex vivo, has provided clues to their functions and a useful set of markers for the study of erythropoiesis...
  14. ncbi request reprint Expression of red cell surface antigens during erythropoiesis
    G Daniels
    Bristol Institute for Transfusion Sciences, UK
    Vox Sang 78:149-53. 2000
    ..We have analysed the appearance and disappearance of cell surface markers during erythropoiesis, in vitro...
  15. ncbi request reprint The clinical significance of blood group antibodies
    G Daniels
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Transfus Med 12:287-95. 2002
  16. ncbi request reprint The low-frequency MNS blood group antigens Ny(a) (MNS18) and Os(a) (MNS38) are associated with GPA amino acid substitutions
    G L Daniels
    Bristol Institute for Transfusion Sciences and the Department of Biochemistry, University of Bristol, UK
    Transfusion 40:555-9. 2000
    ..Antigens of the MNS blood group system are located on two sialoglycoproteins, GPA and GPB, encoded by GYPA and GYPB. The molecular backgrounds of the low-frequency antigens Ny(a) and Os(a) are not known...
  17. doi request reprint Critical band 3 multiprotein complex interactions establish early during human erythropoiesis
    Timothy J Satchwell
    School of Biochemistry, University of Bristol, Bristol, UK
    Blood 118:182-91. 2011
    ..These data are consistent with assembly of major components of the band 3 macrocomplex at an early stage during erythropoiesis...
  18. pmc Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4.2 (-) cells (mutations Chartres 1 and 2)
    Emile van den Akker
    Department of Biochemistry, School of Medical Sciences, University Walk, Bristol, UK
    Haematologica 95:1278-86. 2010
    ..We decided to investigate at which stage of erythropoiesis these hallmarks of protein 4.2 deficiency arise in a novel protein 4.2 patient and whether they cause disruption to the band 3 macrocomplex...
  19. ncbi request reprint Fetal genotyping for the K (Kell) and Rh C, c, and E blood groups on cell-free fetal DNA in maternal plasma
    Kirstin Finning
    International Blood Group Reference Laboratory, NHSBT, Bristol, UK
    Transfusion 47:2126-33. 2007
    ..In many countries this is now done routinely for RhD, by testing cell-free fetal DNA in the maternal plasma. Similar tests for K, C, c, and E are reported...
  20. ncbi request reprint A KEL gene encoding serine at position 193 of the Kell glycoprotein results in expression of KEL1 antigen
    Joyce Poole
    Bristol Institute for Transfusion Sciences and International Blood Group Reference Laboratory, Bristol, UK
    Transfusion 46:1879-85. 2006
    ..Molecular genotyping for KEL*1 is routinely used for assessing whether a fetus is at risk. Red blood cells (RBCs) from a KEL:1 blood donor (D1) were found to have abnormal KEL1 expression during evaluation of anti-KEL1 reagents...
  21. pmc Effect of high throughput RHD typing of fetal DNA in maternal plasma on use of anti-RhD immunoglobulin in RhD negative pregnant women: prospective feasibility study
    Kirstin Finning
    International Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol BS10 5ND
    BMJ 336:816-8. 2008
    ....
  22. ncbi request reprint Two missense mutations in the CD44 gene encode two new antigens of the Indian blood group system
    Joyce Poole
    Bristol Institute for Transfusion Sciences and International Blood Reference Laboratory, National Blood Service, Bristol, UK
    Transfusion 47:1306-11. 2007
    ..The antibodies and RBCs of D and E were mutually compatible, but incompatible with those of Patients A, B, and C. All the antibodies were detected during pregnancy...
  23. ncbi request reprint Noninvasive fetal blood grouping: present and future
    Geoff Daniels
    International Blood Group Reference Laboratory, Bristol Institute for Transfusion Sciences, NHS Blood and Transplant, North Bristol Park, Northway, Filton, Bristol, UK
    Clin Lab Med 30:431-42. 2010
    ....
  24. doi request reprint Noninvasive prenatal diagnosis of fetal blood group phenotypes: current practice and future prospects
    Geoff Daniels
    International Blood Group Reference Laboratory, Bristol Institute for Transfusion Sciences, NHS Blood and Transplant, Bristol, UK
    Prenat Diagn 29:101-7. 2009
    ..Trials suggest that fetal D typing of all D-negative pregnant women is feasible and should become common practice in the near future...
  25. doi request reprint The use of maternal plasma for prenatal RhD blood group genotyping
    Kirstin Finning
    International Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, UK
    Methods Mol Biol 496:143-57. 2009
    ..Fetal D typing has become the standard of care in England in pregnant women with a significant level of anti-D...
  26. doi request reprint Two MER2-negative individuals with the same novel CD151 mutation and evidence for clinical significance of anti-MER2
    Vanja Karamatic Crew
    Bristol Institute for Transfusion Sciences and International Blood Group Reference Laboratory, Bristol, UK
    Transfusion 48:1912-6. 2008
    ..We report here two new examples of alloanti-MER2, in women of Pakistani and Turkish origin, one of whom showed signs of a hemolytic transfusion reaction (HTR) after transfusion of 3 units of red cells (RBCs)...
  27. pmc Differential proteomic analysis of human erythroblasts undergoing apoptosis induced by epo-withdrawal
    Stephanie Pellegrin
    School of Biochemistry, Medical Sciences Building, University Walk, Bristol, United Kingdom
    PLoS ONE 7:e38356. 2012
    ....
  28. ncbi request reprint Blood group antibodies and their significance in transfusion medicine
    Joyce Poole
    International Blood Group Reference Laboratory, Bristol, UK
    Transfus Med Rev 21:58-71. 2007
    ..However, deciding on the clinical significance of an antibody when compatible blood is not immediately available is likely to remain as one of the most common dilemmas facing transfusion practitioners...
  29. ncbi request reprint Different inactivating mutations in the LU genes of three individuals with the Lutheran-null phenotype
    Vanja Karamatic Crew
    Bristol Institute for Transfusion Sciences and International Blood Group Reference Laboratory, Bristol, UK
    Transfusion 47:492-8. 2007
    ..It can arise from three genetic backgrounds: recessive, dominant, or X-linked. Lu(null) of the recessive type appears to result from homozygosity for an inactive LU gene...
  30. ncbi request reprint A clinical service in the UK to predict fetal Rh (Rhesus) D blood group using free fetal DNA in maternal plasma
    Kirstin Finning
    International Blood Group Reference Laboratory, National Blood Service, Bristol BS10 5ND, UK
    Ann N Y Acad Sci 1022:119-23. 2004
    ....
  31. ncbi request reprint JAHK: a low frequency antigen associated with the rG complex of the Rh blood group system
    C Green
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Transfus Med 12:55-61. 2002
    ..JAHK has been assigned the number RH53...
  32. ncbi request reprint Lutheran
    G Daniels
    Bristol Institute for Transfusion Sciences, National Health Service, Blood and Transplant, North Bristol Park, Bristol, UK
    Immunohematology 25:152-9. 2009
    ..They could also be involved in vascular occlusion and thrombotic events as complications of sickle cell disease and polycythemia vera, respectively...
  33. doi request reprint Blood groups: the past 50 years
    Geoff Daniels
    Bristol Institute for Transfusion Sciences, Filton, Bristol, UK
    Transfusion 50:281-9. 2010
    ..This review summarizes key aspects of the discovery of blood groups; the inconsistent terminology that has arisen; and the contribution of blood groups to genetics, safe transfusion, transplantation, evolution, and biology...
  34. ncbi request reprint New mutations in C1GALT1C1 in individuals with Tn positive phenotype
    Vanja Karamatic Crew
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Br J Haematol 142:657-67. 2008
    ..These data show that alteration of O-glycan structures resulting from T-synthase deficiency is accompanied by altered expression of a wide variety of genes in erythroid cells...
  35. ncbi request reprint Sequence variation in the 5' untranslated region of the human A4GALT gene is associated with, but does not define, the P1 blood-group polymorphism
    L Tilley
    Bristol Institute for Transfusion Sciences, National Blood Service, Bristol, UK
    Vox Sang 90:198-203. 2006
    ..This study aimed to confirm this correlation in a larger number of British individuals...
  36. doi request reprint Report of the third international workshop on molecular blood group genotyping
    G Daniels
    Bristol Institute for Transfusion Sciences, NHS Blood and Transplant, North Bristol Park, Northway, Filton, Bristol, UK
    Vox Sang 96:337-43. 2009
    ..The main conclusion for the 2006 workshop can be reiterated: with greater care and attention to detail, very high standards could be set for molecular blood group genotyping...
  37. ncbi request reprint LU21: a new high-frequency antigen in the Lutheran blood group system
    V Karamatic Crew
    Bristol Institute for Transfusion Sciences and International Blood Group Reference Laboratory, National Blood Service, Bristol, UK
    Vox Sang 87:109-13. 2004
    ..The Lutheran blood group system comprises 18 antigens numbered LU1 to LU20, with two numbers obsolete. Thirteen antigens are of high frequency...
  38. pmc The majority of the in vitro erythroid expansion potential resides in CD34(-) cells, outweighing the contribution of CD34(+) cells and significantly increasing the erythroblast yield from peripheral blood samples
    Emile van den Akker
    Department of Biochemistry, School of Medical Sciences, University of Bristol, University Walk, Clifton, Bristol, BS81TD, United Kingdom
    Haematologica 95:1594-8. 2010
    ..This culture system may be particularly useful for investigating the pathophysiology of anemic patients where only small blood volumes are available...
  39. ncbi request reprint CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin
    Vanja Karamatic Crew
    Bristol Institute for Transfusion Sciences, Southmead Road, Bristol, BS10 5ND, United Kingdom
    Blood 104:2217-23. 2004
    ....
  40. ncbi request reprint The BloodGen project: toward mass-scale comprehensive genotyping of blood donors in the European Union and beyond
    Neil D Avent
    Center for Research in Biomedicine and Bristol Genomics Research Institute, Faculty of Applied Sciences, University of the West of England, and Bristol Institute for Transfusion Sciences, Bristol, UK
    Transfusion 47:40S-6S. 2007
  41. ncbi request reprint Section 4: Antibodies to other blood group antigens. Coordinator's report
    G Daniels
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Transfus Clin Biol 9:75-80. 2002
  42. ncbi request reprint The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in africans with the Rh D-negative blood group phenotype
    B K Singleton
    Bristol Institute for Transfusion Sciences, Bristol, England
    Blood 95:12-8. 2000
    ..Consequently, we have developed a new test that detects the 37 bp insert in exon 4 of RHDpsi. (Blood. 2000; 95:12-18)..
  43. ncbi request reprint Molecular bases of the antigens of the Lutheran blood group system
    Vanja Karamatic Crew
    Bristol Institute for Transfusion Sciences, Bristol, UK
    Transfusion 43:1729-37. 2003
    ..There are four pairs of allelic antigens, whereas others are independently expressed antigens of a high frequency. Lutheran antigens are carried by the Lutheran glycoproteins, which are a product of a single gene LU...
  44. doi request reprint The molecular genetics of blood group polymorphism
    Geoff Daniels
    Bristol Institute for Transfusion Sciences, NHS Blood and Transplant, Filton, Bristol, UK
    Hum Genet 126:729-42. 2009
    ..Other applications are being developed for the future...
  45. doi request reprint A new blood group system, RHAG: three antigens resulting from amino acid substitutions in the Rh-associated glycoprotein
    L Tilley
    International Blood Group Reference Laboratory and Bristol Institute for Transfusion Sciences, NHS Blood and Transplant, Bristol, UK
    Vox Sang 98:151-9. 2010
    ..Two high frequency antigens (Duclos and DSLK) and one low frequency antigen (Ol(a)) have serological characteristics suggestive of expression on RhAG...
  46. ncbi request reprint Acquired and transient RBC CD55 deficiency (Inab phenotype) and anti-IFC
    Thomas Matthes
    Division of Hematology, Geneva University Hospital, Geneva, Switzerland
    Transfusion 42:1448-57. 2002
    ..This report describes the first example of a patient with an acquired and transient form of the Inab phenotype...
  47. ncbi request reprint Molecular basis of the JAHK (RH53) antigen
    Erwin A Scharberg
    Red Cross Blood Service of Baden Württemberg Hessen, Institute Baden Baden, Germany
    Transfusion 45:1314-8. 2005
    ..JAHK was allocated the Rh number RH53. The serologic findings indicated the location of the antigen on the RhCE protein, although the molecular basis for JAHK has not been known...
  48. ncbi request reprint Partial D and weak D: can they be distinguished?
    Geoff Daniels
    Transfus Med 17:145-6. 2007
  49. ncbi request reprint Y chromosome detection by Real Time PCR and pyrophosphorolysis-activated polymerisation using free fetal DNA isolated from maternal plasma
    Elles M J Boon
    Leiden University Medical Center, Center for Human and Clinical Genetics, Leiden, The Netherlands
    Prenat Diagn 27:932-7. 2007
    ....
  50. ncbi request reprint Noninvasive genotyping fetal Kell blood group (KEL1) using cell-free fetal DNA in maternal plasma by MALDI-TOF mass spectrometry
    Ying Li
    University Women s Hospital Department of Research, University Hospital, Basel, Switzerland
    Prenat Diagn 28:203-8. 2008
    ....
  51. ncbi request reprint Detection of fetal Rhesus D gene in whole blood of women booking for routine antenatal care [Eur J Obstet Gynecol Reprod Biol 2003;108:29-32]
    Kirstin Finning
    Eur J Obstet Gynecol Reprod Biol 110:117; author reply 118. 2003
  52. ncbi request reprint Altered expression and allelic association of the hypervariable membrane mucin MUC1 in Helicobacter pylori gastritis
    Lynne E Vinall
    Galton Laboratory, Department of Biology, University College London, London, England
    Gastroenterology 123:41-9. 2002
    ..Our aim was to investigate the involvement of MUC1 in chronic gastritis and, by implication, gastric cancer...
  53. ncbi request reprint Chorein detection for the diagnosis of chorea-acanthocytosis
    Carol Dobson-Stone
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Ann Neurol 56:299-302. 2004
    ..However, chorein expression was absent or noticeably reduced in ChAc patient cells, but not McLeod syndrome and Huntington's disease cells. This suggests that loss of chorein expression is a diagnostic feature of ChAc...
  54. ncbi request reprint Towards universal red blood cells
    Geoff Daniels
    Nat Biotechnol 25:427-8. 2007
  55. ncbi request reprint AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL
    Nathalie Roudier
    INSERM U76, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Biol Chem 277:45854-9. 2002
    ..These findings represent the first reported cases of AQP3 deficiency in humans and provide the molecular basis of a new blood group system, GIL, encoded by the AQP3 protein...
  56. ncbi request reprint Causes of fetal anemia in hemolytic disease due to anti-K
    Geoff Daniels
    Transfusion 43:115-6. 2003