Stefania Crotta

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. doi request reprint Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection
    Stefania Crotta
    Department of Microbial Molecular Biology, Novartis Vaccines and Diagnostics, Siena, Italy
    J Hepatol 52:183-90. 2010
  2. pmc Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs
    Pirada Suphaphiphat
    Novartis Vaccines and Diagnostics, Cambridge, MA, USA
    Virol J 7:157. 2010
  3. pmc CD81 is a central regulator of cellular events required for hepatitis C virus infection of human hepatocytes
    Michela Brazzoli
    Department of Molecular Immunology, Novartis Vaccines and Diagnostics, Siena, Italy
    J Virol 82:8316-29. 2008
  4. ncbi request reprint Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells
    Stefania Crotta
    Chiron Vaccines, Siena, Italy
    Eur J Immunol 36:919-29. 2006
  5. ncbi request reprint Intracellular accumulation of hepatitis C virus proteins in a human hepatoma cell line
    Michela Brazzoli
    Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy
    J Hepatol 46:53-9. 2007

Collaborators

  • Cristina Ulivieri
  • Thomas Wileman
  • Qing Zhu
  • Michela Brazzoli
  • Pirada Suphaphiphat
  • Alessia Bianchi
  • Annunziata B Tuccino
  • Mithra Rothfeder
  • Gene Palmer
  • Kara Balabanis
  • Ethan Settembre
  • Peter W Mason
  • Terika Spencer
  • Bjoern Keiner
  • Christian W Mandl
  • Anders Lilja
  • Heidi Trusheim
  • Melissa Sackal
  • Philip R Dormitzer
  • Michael Franti
  • Armin Hekele
  • Amy Weiner
  • Sara Filippini
  • Mariagrazia Pizza
  • Fabio Bagnoli
  • Sergio Abrignani
  • Marcello Merola
  • Paul Monaghan

Detail Information

Publications5

  1. doi request reprint Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection
    Stefania Crotta
    Department of Microbial Molecular Biology, Novartis Vaccines and Diagnostics, Siena, Italy
    J Hepatol 52:183-90. 2010
    ..We have previously demonstrated that natural killer (NK) cells can be inhibited in vitro by recombinant HCV glycoprotein E2 via cross-linking of CD81, a cellular co-receptor for the virus...
  2. pmc Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs
    Pirada Suphaphiphat
    Novartis Vaccines and Diagnostics, Cambridge, MA, USA
    Virol J 7:157. 2010
    ..Thus, we have demonstrated that molecular cloning of members of a quasispecies can help in selection of seed viruses for vaccine manufacture...
  3. pmc CD81 is a central regulator of cellular events required for hepatitis C virus infection of human hepatocytes
    Michela Brazzoli
    Department of Molecular Immunology, Novartis Vaccines and Diagnostics, Siena, Italy
    J Virol 82:8316-29. 2008
    ..In conclusion, we describe a range of cellular events that are manipulated by HCV to coordinate interactions with its multiple coreceptors and to establish productive infections and find that CD81 is a central regulator of these events...
  4. ncbi request reprint Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells
    Stefania Crotta
    Chiron Vaccines, Siena, Italy
    Eur J Immunol 36:919-29. 2006
    ..We propose that tetraspanin engagement leads to comparable cytoskeleton reorganization in T and NK cells, which in turn results in opposite functional outcomes...
  5. ncbi request reprint Intracellular accumulation of hepatitis C virus proteins in a human hepatoma cell line
    Michela Brazzoli
    Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy
    J Hepatol 46:53-9. 2007
    ....