P G Camici

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi request reprint From microcirculation to cardiac event: protection with Preterax
    Paolo G Camici
    Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, London, UK
    J Hypertens Suppl 26:S8-10. 2008
  2. ncbi request reprint The clinical value of myocardial blood flow measurement
    Paolo G Camici
    Medical Research Council, Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, London, United Kingdom
    J Nucl Med 50:1076-87. 2009
  3. doi request reprint Stunning, hibernation, and assessment of myocardial viability
    Paolo G Camici
    Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Imperial College School of Medicine, London, UK
    Circulation 117:103-14. 2008
  4. ncbi request reprint From microcirculation to cardiac event: protection with Preterax
    Paolo G Camici
    Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, London, UK
    J Hypertens 26:S8-S10. 2008
  5. ncbi request reprint Myocardial blood flow in patients with hibernating myocardium
    Paolo G Camici
    MRC Clinical Sciences Centre and National Heart and Lung Institute, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK
    Cardiovasc Res 57:302-11. 2003
  6. ncbi request reprint Pathophysiology and diagnosis of hibernating myocardium in patients with post-ischemic heart failure: the contribution of PET
    Paolo G Camici
    MRC Clinical Sciences Centre and National Heart and Lung Institute, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, United Kingdom
    Ann Nucl Med 17:341-50. 2003
  7. ncbi request reprint Gated PET and ventricular volume
    Paolo G Camici
    Hammersmith Hospital, London, United Kingdom
    J Nucl Med 44:1662. 2003
  8. pmc Myocardial hibernation and heart failure: introduction
    P G Camici
    MRC Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Heart 90:136. 2004
  9. ncbi request reprint Coronary microvascular dysfunction
    Paolo G Camici
    Medical Research Council Clinical Sciences Centre Hammersmith Hospital, and National Heart and Lung Institute, Imperial College, London, United Kingdom
    N Engl J Med 356:830-40. 2007
  10. ncbi request reprint The contribution of hibernation to heart failure
    Paolo G Camici
    MRC Clinical Sciences Centre, Hammersmith Hospital, DuCane Road, London W12 ONN, UK
    Ann Med 36:440-7. 2004

Detail Information

Publications79

  1. ncbi request reprint From microcirculation to cardiac event: protection with Preterax
    Paolo G Camici
    Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, London, UK
    J Hypertens Suppl 26:S8-10. 2008
    ..This suggests that coronary microvascular dysfunction can be reversed by treatment with these drugs and might contribute to the prevention of ischaemic heart disease in these patients...
  2. ncbi request reprint The clinical value of myocardial blood flow measurement
    Paolo G Camici
    Medical Research Council, Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, London, United Kingdom
    J Nucl Med 50:1076-87. 2009
    ....
  3. doi request reprint Stunning, hibernation, and assessment of myocardial viability
    Paolo G Camici
    Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Imperial College School of Medicine, London, UK
    Circulation 117:103-14. 2008
  4. ncbi request reprint From microcirculation to cardiac event: protection with Preterax
    Paolo G Camici
    Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, London, UK
    J Hypertens 26:S8-S10. 2008
    ..This suggests that coronary microvascular dysfunction can be reversed by treatment with these drugs and might contribute to the prevention of ischaemic heart disease in these patients...
  5. ncbi request reprint Myocardial blood flow in patients with hibernating myocardium
    Paolo G Camici
    MRC Clinical Sciences Centre and National Heart and Lung Institute, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK
    Cardiovasc Res 57:302-11. 2003
    ....
  6. ncbi request reprint Pathophysiology and diagnosis of hibernating myocardium in patients with post-ischemic heart failure: the contribution of PET
    Paolo G Camici
    MRC Clinical Sciences Centre and National Heart and Lung Institute, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, United Kingdom
    Ann Nucl Med 17:341-50. 2003
    ..The recent evidence that repetitive ischemia in patients can be cumulative and lead to more severe and prolonged stunning, lends further support to the hypothesis that, at least initially, stunning and HM are two facets of the same coin...
  7. ncbi request reprint Gated PET and ventricular volume
    Paolo G Camici
    Hammersmith Hospital, London, United Kingdom
    J Nucl Med 44:1662. 2003
  8. pmc Myocardial hibernation and heart failure: introduction
    P G Camici
    MRC Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Heart 90:136. 2004
  9. ncbi request reprint Coronary microvascular dysfunction
    Paolo G Camici
    Medical Research Council Clinical Sciences Centre Hammersmith Hospital, and National Heart and Lung Institute, Imperial College, London, United Kingdom
    N Engl J Med 356:830-40. 2007
  10. ncbi request reprint The contribution of hibernation to heart failure
    Paolo G Camici
    MRC Clinical Sciences Centre, Hammersmith Hospital, DuCane Road, London W12 ONN, UK
    Ann Med 36:440-7. 2004
    ..Recent evidence that repetitive ischaemia in patients can be cumulative and lead to more severe and prolonged stunning, lends further support to the hypothesis that, at least initially, stunning and HM are two facets of the same coin...
  11. pmc Hibernation and heart failure
    P G Camici
    MRC Clinical Sciences Centre, Hammersmith Hospital, DuCane Road, London W12 ONN, UK
    Heart 90:141-3. 2004
  12. ncbi request reprint The brain-heart axis in the perception of cardiac pain: the elusive link between ischaemia and pain
    S D Rosen
    MRC Cyclotron Unit and Imperial College School of Medicine, London, UK
    Ann Med 32:350-64. 2000
    ..In conclusion, we present a unified view of the cerebral handling of afferent signals from the heart throughout this spectrum of experience of chest pain, a view that accounts for the clinical features of the patients studied...
  13. ncbi request reprint Effect of alpha1-adrenoceptor blockade on coronary vasodilator reserve in cardiac syndrome X
    S D Rosen
    MRC Cyclotron Unit, Hammersmith Hospital, London, England
    J Cardiovasc Pharmacol 34:554-60. 1999
    ..The data do not support the case for alpha1-mediated vasoconstriction having an etiologic role in the chest pain of syndrome X...
  14. ncbi request reprint The contribution of positron emission tomography to the study of ischemic heart failure
    D P Dutka
    MRC Clinical Sciences Centre, Imperial College School of Medicine, London, England
    Prog Cardiovasc Dis 43:399-418. 2001
    ..The advances and the need for further studies to establish both the natural history of such ventricular dysfunction and the role of coronary revascularization are discussed...
  15. ncbi request reprint Rigid-body transformation of list-mode projection data for respiratory motion correction in cardiac PET
    L Livieratos
    PET Cardiology, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, UK
    Phys Med Biol 50:3313-22. 2005
    ..Quantitative assessment of preliminary C15O patient data showed improvement in the recovery coefficient at the centre of the left ventricle...
  16. ncbi request reprint PET measurement of the coronary flow reserve and microcirculatory function
    O Rimoldi
    MRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK
    Herz 24:522-30. 1999
    ..The action of calcium antagonists on the coronary microcirculation can contribute to explain the efficacy of these drugs against ischemia and ischemia-reperfusion damage...
  17. pmc Dobutamine-induced hyperaemia inversely correlates with coronary artery stenosis severity and highlights dissociation between myocardial blood flow and oxygen consumption
    R Jagathesan
    MRC Clinical Sciences Centre, Imperial College, London, UK
    Heart 92:1230-7. 2006
    ..To compare the relationship between dobutamine myocardial blood flow (MBF), rate-pressure product (RPP) and stenosis severity in patients with coronary artery disease (CAD)...
  18. pmc Coronary microvascular dysfunction in male patients with Anderson-Fabry disease and the effect of treatment with alpha galactosidase A
    P M Elliott
    The Heart Hospital, University College London, London, UK
    Heart 92:357-60. 2006
    ..To measure coronary flow reserve (CFR), an index of microvascular function, in Anderson-Fabry disease (AFD) at baseline and after enzyme replacement therapy (ERT)...
  19. ncbi request reprint Measurement of myocardial blood flow with positron emission tomography before and after transmyocardial laser revascularization
    O Rimoldi
    MRC Cyclotron Unit Imperial College School of Medicine, Hammersmith Hospital, London, UK
    Circulation 100:II134-8. 1999
    ..It has been hypothesized that transmural left ventricular channels created by laser improve myocardial blood flow (MBF) in the treated zones. We aimed to assess the effect of TMLR on MBF and coronary vasodilator reserve (CVR)...
  20. ncbi request reprint Positron emission tomography to assess the haemodynamics of the coronary circulation
    P G Camici
    MRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK
    Semin Interv Cardiol 3:31-8. 1998
    ..This technique allows the assessment of the functional significance of epicardial coronary stenoses as well as the investigation of the function of the coronary microcirculation in patients with and without coronary artery disease...
  21. ncbi request reprint Selection, design and evaluation of new radioligands for PET studies of cardiac adrenoceptors
    V W Pike
    MRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK
    Pharm Acta Helv 74:191-200. 2000
    ..Alternative radioligands are in development for beta-ARs, including beta 1-selective radioligands. A promising radioligand for imaging myocardial alpha 1-ARs, [11C]GB67, is now being evaluated in human PET experiments...
  22. ncbi request reprint Repetitive myocardial stunning in pigs is associated with the increased expression of inducible and constitutive nitric oxide synthases
    C S Baker
    Department of Cardiology, Hammersmith Hospital, Imperial College School of Medicine, London, UK
    Cardiovasc Res 43:685-97. 1999
    ..The goal of this study was to examine the result of repetitive myocardial stunning on myocardial NO release and expression of inducible (iNOS) and constitutive (eNOS) NO synthases...
  23. ncbi request reprint Limitation of coronary reserve after successful angioplasty is prevented by oral pretreatment with an alpha1-adrenergic antagonist
    O Rimoldi
    MRC Clinical Sciences Centre, Hammersmith Hospital, London, England, UK
    J Cardiovasc Pharmacol 36:310-5. 2000
    ..53 +/- 0.92 and 2.48 +/- 0.80, respectively; p = NS). Treatment with oral doxazosin in addition to standard antianginal therapy can prevent the impairment of CVR frequently observed despite successful PTCA...
  24. pmc Central neural contribution to the perception of chest pain in cardiac syndrome X
    S D Rosen
    MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, London, UK
    Heart 87:513-9. 2002
    ..To investigate the central neural contribution to chest pain perception in cardiac syndrome X (angina-like pain, ECG changes during stress, angiographically normal coronary arteriogram)...
  25. ncbi request reprint In vivo imaging of insulin receptors by PET: preclinical evaluation of iodine-125 and iodine-124 labelled human insulin
    P Iozzo
    MRC Clinical Sciences Centre, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
    Nucl Med Biol 29:73-82. 2002
    ..The heart, liver and kidneys were visualized using [(124)I]iodoinsulin with PET...
  26. ncbi request reprint Incidence of stunned, hibernating and scarred myocardium in ischaemic cardiomyopathy
    Miguel Hernandez-Pampaloni
    Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, Imperial College, London, UK
    Eur J Nucl Med Mol Imaging 32:314-21. 2005
    ..The aim of this study was to evaluate, in a large number of patients, the prevalence of these different patterns by purely quantitative means...
  27. ncbi request reprint Assessment of the long-term reproducibility of baseline and dobutamine-induced myocardial blood flow in patients with stable coronary artery disease
    Rohan Jagathesan
    Medical Research Council Clinical Sciences Centre, Imperial College, London W12 N00, UK
    J Nucl Med 46:212-9. 2005
    ..PET allows accurate, noninvasive quantification of myocardial blood flow (MBF) and coronary flow reserve (CFR). The aim of the study was to investigate the long-term reproducibility of Dob stress on MBF and CFR in CAD patients using PET...
  28. ncbi request reprint Myocardial blood flow measurement by PET: technical aspects and clinical applications
    Philipp A Kaufmann
    Nuclear Cardiology Section, Cardiovascular Center, University Hospital, Zurich, Switzerland
    J Nucl Med 46:75-88. 2005
  29. ncbi request reprint Myocardial ischaemia and metabolic memory
    Paolo G Camici
    Eur J Nucl Med Mol Imaging 33:4-5. 2006
  30. ncbi request reprint Basal and hyperaemic myocardial blood flow in regionally denervated canine hearts: an in vivo study with positron emission tomography
    Ornella E Rimoldi
    MRC Clinical Sciences Centre, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK
    Eur J Nucl Med Mol Imaging 34:197-205. 2007
    ....
  31. ncbi request reprint Quantification of subendocardial and subepicardial blood flow using 15O-labeled water and PET: experimental validation
    Ornella Rimoldi
    Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, United Kingdom
    J Nucl Med 47:163-72. 2006
    ....
  32. pmc Hemodialysis-induced cardiac dysfunction is associated with an acute reduction in global and segmental myocardial blood flow
    Christopher W McIntyre
    Department of Renal Medicine, Derby City Hospital, Uttoxeter Road, Derby, DE22 3NE, UK
    Clin J Am Soc Nephrol 3:19-26. 2008
    ..This study used serial intradialytic H(2)(15)O positron emission tomography scanning to confirm that the development of dialysis-induced RWMAs was associated with reduction in myocardial blood flow (MBF)...
  33. ncbi request reprint Myocardial pre-synaptic sympathetic function correlates with glucose uptake in the failing human heart
    Marco Mongillo
    Medical Research Council Clinical Sciences Centre, Imperial College Faculty of Medicine, Hammersmith Hospital, Du Cane Road, London, UK
    Eur J Nucl Med Mol Imaging 34:1172-7. 2007
    ..As the failing heart is characterized by increased sympathetic drive, we hypothesized that there is a correlation between pre-synaptic sympathetic function and insulin sensitivity in the myocardium of patients with HF...
  34. ncbi request reprint Pioglitazone improves myocardial blood flow and glucose utilization in nondiabetic patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled study
    Rossi P Naoumova
    Medical Research Council Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, United Kingdom
    J Am Coll Cardiol 50:2051-8. 2007
    ....
  35. ncbi request reprint Effects of long-term oral dipyridamole treatment on coronary microcirculatory function in patients with chronic stable angina: A substudy of the persantine in stable angina (PISA) study
    Rohan Jagathesan
    MRC Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, London, UK
    J Cardiovasc Pharmacol 48:110-6. 2006
    ..Therefore, we measured the effects of dipyridamole on myocardial blood flow (MBF) and coronary flow reserve (CFR) by using positron emission tomography and H2O in patients with coronary artery disease...
  36. ncbi request reprint Determinants of coronary microvascular dysfunction in symptomatic hypertrophic cardiomyopathy
    Paul Knaapen
    Department of Cardiology, VU University Medical Center, Institute for Cardiovascular Research, Amsterdam, The Netherlands
    Am J Physiol Heart Circ Physiol 294:H986-93. 2008
    ..These observations suggest that, in addition to reduced capillary density caused by hypertrophy, extravascular compressive forces contribute to microvascular dysfunction in HCM patients...
  37. ncbi request reprint Comparison of myocardial blood flow and coronary flow reserve during dobutamine and adenosine stress: Implications for pharmacologic stress testing in coronary artery disease
    Rohan Jagathesan
    MRC Clinical Sciences Centre, Imperial College, London, United Kingdom
    J Nucl Cardiol 13:324-32. 2006
    ..Mechanistic differences between pharmacologic stressors may offer different clinical benefits. Therefore the effects of dobutamine and adenosine on absolute myocardial blood flow (MBF) and coronary flow reserve (CFR) were compared...
  38. ncbi request reprint Spatial relationship between coronary microvascular dysfunction and delayed contrast enhancement in patients with hypertrophic cardiomyopathy
    Barbara Sotgia
    Department of Clinical Physiopathology Nuclear Medicine Unit, Azienda Ospedaliera Universitaria Careggi, Florence, Italy
    J Nucl Med 49:1090-6. 2008
    ....
  39. ncbi request reprint Myocardial glucose transport and utilization in patients with type 2 diabetes mellitus, left ventricular dysfunction, and coronary artery disease
    David P Dutka
    Cardiovascular Medicine, Department of Medicine, University of Cambridge, Cambridge, United Kingdom
    J Am Coll Cardiol 48:2225-31. 2006
    ..This research was designed to assess the effect of type 2 diabetes mellitus (T2DM) on myocardial glucose utilization in patients with heart failure secondary to coronary artery disease...
  40. ncbi request reprint Relevance of coronary microvascular flow impairment to long-term remodeling and systolic dysfunction in hypertrophic cardiomyopathy
    Iacopo Olivotto
    Regional Referral Center for Myocardial Diseases, Florence, Italy
    J Am Coll Cardiol 47:1043-8. 2006
    ....
  41. ncbi request reprint Respiratory gating of cardiac PET data in list-mode acquisition
    Lefteris Livieratos
    PET Cardiology, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, UK
    Eur J Nucl Med Mol Imaging 33:584-8. 2006
    ..Respiratory motion has been identified as a source of artefacts in most medical imaging modalities. This paper reports on respiratory gating as a means to eliminate motion-related inaccuracies in PET imaging...
  42. ncbi request reprint Coronary microvascular dysfunction and ischemia in hypertrophic cardiomyopathy. Mechanisms and clinical consequences
    Iacopo Olivotto
    Regional Referral Center for Myocardial Diseases, Department of Cardiology, Careggi University Hospital, Florence, Italy
    Ital Heart J 5:572-80. 2004
    ..The aim of this article is to provide a concise overview of the available evidence of microvascular dysfunction and ischemia in HCM, and to speculate on the potential implications for management...
  43. ncbi request reprint Cardiac applications of PET
    Paolo G Camici
    National Heart and Lung Institute and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College School of Science, Technology and Medicine, Hammersmith Hospital, UK
    Kaku Igaku 39:223-5. 2002
  44. ncbi request reprint Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy
    Franco Cecchi
    Regional Referral Center for Myocardial Diseases, Azienda Ospedaliera Careggi, Florence, Italy
    N Engl J Med 349:1027-35. 2003
    ..We prospectively evaluated a cohort of patients with hypertrophic cardiomyopathy after they had undergone quantitative assessment of myocardial blood flow by positron-emission tomography (PET)...
  45. ncbi request reprint Low frequency spectral component of heart rate variability and myocardial beta-adrenoceptor density after acute myocardial infarction
    Stefano Guzzetti
    Università degli Studi Milano, Italy
    Basic Res Cardiol 97:97-104. 2002
    ....
  46. ncbi request reprint Functional changes in coronary microcirculation after valve replacement in patients with aortic stenosis
    Kim Rajappan
    Academic Cardiology Unit, St Mary s Hospital, London, UK
    Circulation 107:3170-5. 2003
    ....
  47. ncbi request reprint Hibernation and congestive heart failure
    David P Dutka
    Department of Cardiovascular Medicine, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Heart Fail Rev 8:167-73. 2003
    ....
  48. ncbi request reprint Accuracy of PET in predicting functional recovery after revascularisation in patients with chronic ischaemic dysfunction: head-to-head comparison between blood flow, glucose utilisation and water-perfusable tissue fraction
    Jeroen J Bax
    Leiden University Medical Center, The Netherlands
    Eur J Nucl Med Mol Imaging 29:721-7. 2002
    ..It is concluded that metabolic imaging is superior to perfusion-based indexes for assessment of the potential for functional recovery after revascularisation...
  49. ncbi request reprint Measurement of ventricular volumes and function: a comparison of gated PET and cardiovascular magnetic resonance
    Kim Rajappan
    Cardiovascular MR Unit, Royal Brompton Hospital, National Heart and Lung Institute, London, United Kingdom
    J Nucl Med 43:806-10. 2002
    ..The aim of this study was to compare cardiac volume and function assessment using PET with the reference technique of cardiovascular magnetic resonance (CMR)...
  50. ncbi request reprint Absolute quantification of myocardial blood flow with H(2)(15)O and 3-dimensional PET: an experimental validation
    Klaus P Schafers
    Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, United Kingdom
    J Nucl Med 43:1031-40. 2002
    ..The purpose of this study was to assess a 3-dimensional (3D)-only PET scanner (ECAT EXACT3D) for its use in the absolute quantification of myocardial blood flow (MBF) using H(2)(15)O...
  51. ncbi request reprint Myocardial beta-adrenoceptor density one month after acute myocardial infarction predicts left ventricular volumes at six months
    Nicos Spyrou
    Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Faculty of Medicine, Imperial College, London, United Kingdom
    J Am Coll Cardiol 40:1216-24. 2002
    ....
  52. ncbi request reprint [Stunning, hibernation, and heart failure in patients with coronary disease: crucial role of impaired coronary flow reserve]
    Mariella Montano
    MRC Clinical Sciences Centre, Imperial College of Science Technology and Medicine, Hammersmith Hospital, London, UK
    Ital Heart J Suppl 4:727-32. 2003
    ..These findings have contributed to a new pathophysiological theory of hibernation where repetitive ischemia and stunning are considered as the initial mechanisms that might start the process of myocardial hibernation...
  53. ncbi request reprint Effect of repeated episodes of reversible myocardial ischemia on myocardial blood flow and function in humans
    Edward Barnes
    Division of Cardiology and Medical Research Council, National Heart and Lung Institute, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, United Kingdom
    Am J Physiol Heart Circ Physiol 282:H1603-8. 2002
    ..15 +/- 0.39 and 1.20 +/- 0.43, respectively) was no different to baseline MBF (1.02 +/- 0.35), confirming that repeated episodes of dobutamine-induced ischemia lead to cumulative myocardial stunning...
  54. ncbi request reprint Abnormal myocardial presynaptic norepinephrine recycling in patients with Brugada syndrome
    Peter Kies
    Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Str 33, D 48149 Munster, Germany
    Circulation 110:3017-22. 2004
    ..The aim of this study was to investigate presynaptic and postsynaptic myocardial sympathetic function in patients with Brugada syndrome...
  55. ncbi request reprint Systemic inhibition of nitric oxide synthase unmasks neural constraint of maximal myocardial blood flow in humans
    Philipp A Kaufmann
    MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, UK
    Circulation 110:1431-6. 2004
    ..We assessed the effect of simultaneous inhibition of both endothelial (eNOS) and neuronal (nNOS) NO synthase isoforms on myocardial blood flow (MBF) and coronary flow reserve (CFR) in volunteers and in (denervated) transplant recipients...
  56. ncbi request reprint Positron emission tomography for quantitation of myocardial perfusion
    Ornella E Rimoldi
    Medical Research Council Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
    J Nucl Cardiol 11:482-90. 2004
  57. ncbi request reprint Independent association of type 2 diabetes and coronary artery disease with myocardial insulin resistance
    Patricia Iozzo
    Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, UK
    Diabetes 51:3020-4. 2002
    ..We conclude that type 2 diabetes is specifically associated with myocardial IR that is independent of and nonadditive with angiographic CAD and proportional to skeletal muscle and whole-body IR...
  58. ncbi request reprint Mechanisms of coronary microcirculatory dysfunction in patients with aortic stenosis and angiographically normal coronary arteries
    Kim Rajappan
    Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Circulation 105:470-6. 2002
    ....
  59. ncbi request reprint Absolute blood flow and oxygen consumption in stunned myocardium in patients with coronary artery disease
    Edward Barnes
    MRC Clinical Sciences Centre and Division of Cardiology, National Heart and Lung Institute, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
    J Am Coll Cardiol 39:420-7. 2002
    ....
  60. ncbi request reprint Assessment of infarct size by positron emission tomography and [18F]2-fluoro-2-deoxy-D-glucose: a new absolute threshold technique
    Panithaya Chareonthaitawee
    MRC, Clinical Sciences Centre, Imperial College School of Science Technology and Medicine, London, UK
    Eur J Nucl Med Mol Imaging 29:203-15. 2002
    ....
  61. ncbi request reprint Regional myocardial blood flow and glucose utilization during fasting and physiological hyperinsulinemia in humans
    Patricia Iozzo
    Medical Research Council Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London W12 ONN, United Kingdom
    Am J Physiol Endocrinol Metab 282:E1163-71. 2002
    ..Furthermore, regional distribution of insulin-stimulated MBF and MGU does not appear to be uniform across the left ventricular wall of healthy subjects...
  62. ncbi request reprint Program of cell survival underlying human and experimental hibernating myocardium
    Christophe Depre
    Department of Cell Biology and Molecular Medicine and The Cardiovascular Research Institute, University of Medicine and Dentistry New Jersey, Newark 07103, USA
    Circ Res 95:433-40. 2004
    ..Potentially, promoting such a program offers a novel opportunity to salvage postmitotic tissues in conditions of ischemia...
  63. ncbi request reprint Is the chest pain in cardiac syndrome X due to subendocardial ischaemia?
    Paolo G Camici
    Eur Heart J 28:1539-40. 2007
  64. ncbi request reprint Immunocytochemical evidence for inducible nitric oxide synthase and cyclooxygenase-2 expression with nitrotyrosine formation in human hibernating myocardium
    Christopher S R Baker
    MRC Clinical Sciences Centre, Imperial College Faculty of Medicine, Hammersmith Hospital, London, United Kingdom
    Basic Res Cardiol 97:409-15. 2002
    ....
  65. ncbi request reprint Evaluation of the microcirculation in hypertension and cardiovascular disease
    Harry A J Struijker-Boudier
    CARIM Cardiovascular Research Institute Maastricht, Maastricht University, Universiteitssingel 50, PO Box 616, 6200 MD Maastricht, The Netherlands
    Eur Heart J 28:2834-40. 2007
    ..Closer attention to the microcirculation will ultimately improve the treatment and prevention of many of the most important forms of cardiovascular disease...
  66. ncbi request reprint [Guidelines on the management of stable angina pectoris. Executive summary]
    Kim Fox
    Sociedad europea de cardiologia
    Rev Esp Cardiol 59:919-70. 2006
  67. ncbi request reprint [Guidelines on the management of stable angina pectoris: executive summary]
    Kim Fox
    G Ital Cardiol (Rome) 7:535-83. 2006
  68. ncbi request reprint Guidelines for percutaneous coronary interventions. The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology
    Sigmund Silber
    Kardiologische Praxis und Praxisklinik, Munchen, Germany
    Eur Heart J 26:804-47. 2005
    ....
  69. ncbi request reprint Tetrahydrobiopterin restores impaired coronary microvascular dysfunction in hypercholesterolaemia
    Christophe A Wyss
    Nuclear Cardiology, Cardiovascular Center, University Hospital, C NUK 32, Ramistrasse 100, CH 8091, Zurich, Switzerland
    Eur J Nucl Med Mol Imaging 32:84-91. 2005
    ..We studied whether BH4 deficiency contributes to the coronary microcirculatory dysfunction observed in patients with hypercholesterolaemia...
  70. ncbi request reprint [Guidelines for percutaneous coronary interventions]
    Sigmund Silber
    Rev Esp Cardiol 58:679-728. 2005
  71. ncbi request reprint [Guidelines for percutaneous coronary interventions]
    Sigmund Silber
    Ital Heart J Suppl 6:427-74. 2005
  72. ncbi request reprint Is central nervous system processing altered in patients with heart failure?
    Stuart D Rosen
    Department of Respiratory Physiology, National Heart and Lung Institute, Imperial College, Charing Cross Hospital, London W68RP, UK
    Eur Heart J 25:952-62. 2004
    ..Our aim was to assess whether heart failure patients exhibit different patterns of regional brain activation after exercise stress...
  73. ncbi request reprint Improvement of impaired coronary vasodilator reserve in hypertensive patients by low-dose ACE inhibitor/diuretic therapy: a pilot PET study
    Jean Jacques Mourad
    St Michel Hospital, Paris, France
    J Renin Angiotensin Aldosterone Syst 4:94-5. 2003
  74. ncbi request reprint Occurrence of regional left ventricular dysfunction in patients undergoing standard and biofeedback dialysis
    Nicholas M Selby
    Department of Renal Medicine, Derby City Hospital, Derby, London, UK
    Am J Kidney Dis 47:830-41. 2006
    ..Recurrent subclinical myocardial ischemia is important in the genesis of heart failure in nondialysis patients. We examined whether this phenomenon occurs in response to the stress of hemodialysis (HD)...
  75. ncbi request reprint Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology
    Kim Fox
    Department of Cardiology, Royal Brompton Hospital, London, UK
    Eur Heart J 27:1341-81. 2006
  76. ncbi request reprint Is the chest pain in cardiac syndrome X due to subendocardial ischaemia?
    Paolo G Camici
    Ital Heart J 3:623-5. 2002
  77. ncbi request reprint Effect of left ventricular assist device combination therapy on myocardial blood flow in patients with end-stage dilated cardiomyopathy
    Patrick Tansley
    Harefield Research Foundation, Harefield Hospital, Harefield, Middlesex, UK
    J Heart Lung Transplant 23:1283-9. 2004
    ..The aim of this study was to assess the impact of left ventricular unloading using left ventricular assist device (LVAD) combination therapy on resting MBF and CFR in patients with end-stage heart disease...
  78. ncbi request reprint [Guidelines on the management of stable angina pectoris; the experts of the European Society of Cardiology on the management of stable angina pectoris]
    Kim Fox
    Department of Cardiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Kardiol Pol 64:823-80. 2006
  79. ncbi request reprint Systemic nitric oxide synthase inhibition improves coronary flow reserve to adenosine in patients with significant stenoses
    Philipp A Kaufmann
    Medical Research Council Clinical Sciences Center, Imperial College, Hammersmith Hospital, London, United Kingdom
    Am J Physiol Heart Circ Physiol 293:H2178-82. 2007
    ..Similarly to our previous findings in normal volunteers, this suggests that adenosine-induced hyperemia in CAD patients is constrained by a mechanism that can be relieved by systemic NOS inhibition with L-NMMA...