M Breen

Summary

Affiliation: National Institute for Medical Research
Country: UK

Publications

  1. ncbi request reprint FISH mapping and identification of canine chromosomes
    M Breen
    Preventive Medicine, Animal Health Trust, Newmarket, Suffolk, U K
    J Hered 90:27-30. 1999
  2. ncbi request reprint The DAPI banded karyotype of the domestic dog (Canis familiaris) generated using chromosome-specific paint probes
    M Breen
    Animal Health Trust, Kentford, Suffolk, UK
    Chromosome Res 7:401-6. 1999
  3. ncbi request reprint Reciprocal chromosome painting reveals detailed regions of conserved synteny between the karyotypes of the domestic dog (Canis familiaris) and human
    M Breen
    Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, CB8 7UU, United Kingdom
    Genomics 61:145-55. 1999
  4. pmc Chromosome-specific single-locus FISH probes allow anchorage of an 1800-marker integrated radiation-hybrid/linkage map of the domestic dog genome to all chromosomes
    M Breen
    Genetics Section, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK
    Genome Res 11:1784-95. 2001
  5. ncbi request reprint Zoo-FISH analysis of dog chromosome 5: identification of conserved synteny with human and cat chromosomes
    R Thomas
    Centre for Preventive Medicine, Animal Health Trust, Newmarket, Suffolk, UK
    Cytogenet Cell Genet 87:4-10. 1999
  6. ncbi request reprint Molecular cytogenetic analysis of a novel high-grade canine T-lymphoblastic lymphoma demonstrating co-expression of CD3 and CD79a cell markers
    R Thomas
    Genetics Section, Animal Health Trust, Newmarket, Suffolk, UK
    Chromosome Res 9:649-57. 2001
  7. ncbi request reprint Chromosome assignment of six dog genes by FISH, and correlation with dog-human Zoo-FISH data
    R Thomas
    Genetics Section, Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, CB8 7UU, UK
    Anim Genet 32:148-51. 2001
  8. ncbi request reprint A canine cancer-gene microarray for CGH analysis of tumors
    R Thomas
    Oncology Research Group, Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, UK
    Cytogenet Genome Res 102:254-60. 2003
  9. ncbi request reprint An integrated cytogenetic, radiation-hybrid, and comparative map of dog chromosome 5
    R Thomas
    Genetics Section, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, CB8 7UU, UK
    Mamm Genome 12:371-5. 2001
  10. ncbi request reprint Comparative genomic hybridization (CGH) in dogs--application to the study of a canine glial tumour cell line
    K A Dunn
    Pathology Section, Animal Health Trust, Newmarket, Suffolk, UK
    Vet J 160:77-82. 2000

Detail Information

Publications14

  1. ncbi request reprint FISH mapping and identification of canine chromosomes
    M Breen
    Preventive Medicine, Animal Health Trust, Newmarket, Suffolk, U K
    J Hered 90:27-30. 1999
    ..In this way a collection of chromosome-specific cosmid clones is being constructed, comprising at least one marker per chromosome, which will allow anchoring of existing and future linkage groups to the physical map...
  2. ncbi request reprint The DAPI banded karyotype of the domestic dog (Canis familiaris) generated using chromosome-specific paint probes
    M Breen
    Animal Health Trust, Kentford, Suffolk, UK
    Chromosome Res 7:401-6. 1999
    ..These data will facilitate the accurate assignment of FISH-mapped loci to all chromosomes comprising the karyotype and form the basis for an agreed standard of the dog karyotype...
  3. ncbi request reprint Reciprocal chromosome painting reveals detailed regions of conserved synteny between the karyotypes of the domestic dog (Canis familiaris) and human
    M Breen
    Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, CB8 7UU, United Kingdom
    Genomics 61:145-55. 1999
    ..The distribution of conserved segments is discussed, as are the applications of these data in refining the current status of the dog genome map...
  4. pmc Chromosome-specific single-locus FISH probes allow anchorage of an 1800-marker integrated radiation-hybrid/linkage map of the domestic dog genome to all chromosomes
    M Breen
    Genetics Section, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK
    Genome Res 11:1784-95. 2001
    ....
  5. ncbi request reprint Zoo-FISH analysis of dog chromosome 5: identification of conserved synteny with human and cat chromosomes
    R Thomas
    Centre for Preventive Medicine, Animal Health Trust, Newmarket, Suffolk, UK
    Cytogenet Cell Genet 87:4-10. 1999
    ..No suitable gene markers were available for analysis of the fourth segment. The significance of these findings is discussed with reference to current and future dog genome mapping efforts...
  6. ncbi request reprint Molecular cytogenetic analysis of a novel high-grade canine T-lymphoblastic lymphoma demonstrating co-expression of CD3 and CD79a cell markers
    R Thomas
    Genetics Section, Animal Health Trust, Newmarket, Suffolk, UK
    Chromosome Res 9:649-57. 2001
    ..This study represents the first report of the combined application of both direct and indirect cytogenetic techniques for the analysis of recurrent chromosome aberrations in canine cancer...
  7. ncbi request reprint Chromosome assignment of six dog genes by FISH, and correlation with dog-human Zoo-FISH data
    R Thomas
    Genetics Section, Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, CB8 7UU, UK
    Anim Genet 32:148-51. 2001
    ....
  8. ncbi request reprint A canine cancer-gene microarray for CGH analysis of tumors
    R Thomas
    Oncology Research Group, Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, UK
    Cytogenet Genome Res 102:254-60. 2003
    ..We outline the principles of canine microarray development, and present data obtained from microarray analysis of three canine lymphoma cases previously characterized using conventional cytogenetic techniques...
  9. ncbi request reprint An integrated cytogenetic, radiation-hybrid, and comparative map of dog chromosome 5
    R Thomas
    Genetics Section, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, CB8 7UU, UK
    Mamm Genome 12:371-5. 2001
    ....
  10. ncbi request reprint Comparative genomic hybridization (CGH) in dogs--application to the study of a canine glial tumour cell line
    K A Dunn
    Pathology Section, Animal Health Trust, Newmarket, Suffolk, UK
    Vet J 160:77-82. 2000
    ..This report describes the first application of CGH in the dog, illustrated by the analysis of DNA isolated from a canine glial tumour cell line...
  11. ncbi request reprint Isolation and chromosomal assignment of canine genomic BAC clones representing 25 cancer-related genes
    R Thomas
    Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, UK
    Cytogenet Genome Res 102:249-53. 2003
    ....
  12. ncbi request reprint First comprehensive low-density horse linkage map based on two 3-generation, full-sibling, cross-bred horse reference families
    J Swinburne
    Animal Health Trust, Newmarket, CB8 7UU, United Kingdom
    Genomics 66:123-34. 2000
    ....
  13. ncbi request reprint Physical and linkage mapping of the canine phosphate carrier (SLC25A3) and apoptotic activating factor 1 (APAF1) genes to canine chromosome 15
    S Debenham
    Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, CB8 7UU, UK
    Anim Genet 32:50-1. 2001
  14. pmc Chromosome aberrations in canine multicentric lymphomas detected with comparative genomic hybridisation and a panel of single locus probes
    R Thomas
    Oncology Research Section, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK
    Br J Cancer 89:1530-7. 2003
    ..We have also assembled a panel of 41 canine chromosome-specific BAC probes that may be used for accurate and efficient chromosome identification in future studies of this nature...