- A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysisNicola J Beresford
Faculty of Life Sciences, Michael Smith Building, University of Manchester, Manchester M13 9PT, UK
BMC Genomics 11:457. 2010..We used this P-loop signature as a "diagnostic motif" to identify related putative phosphatases with phosphoinositide activity in other organisms...
- Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophagesNicola J Beresford
University of Manchester, UK
J Antimicrob Chemother 63:928-36. 2009..tuberculosis and contributes to its survival within host macrophages. The aim of this study was to identify potent selective inhibitors of MptpB and to determine the efficacy of these compounds in mycobacterium-infected macrophages...