Affiliation: National Institute for Medical Research
Xi L, de Falco P, Barbieri E, Karunaratne A, Bentley L, Esapa C, et al. Bone matrix development in steroid-induced osteoporosis is associated with a consistently reduced fibrillar stiffness linked to altered bone mineral quality. Acta Biomater. 2018;76:295-307 pubmed publisher
..These results will help in the design of new composite musculoskeletal implants for bone repair. ..
Karunaratne A, Xi L, Bentley L, Sykes D, Boyde A, Esapa C, et al. Multiscale alterations in bone matrix quality increased fragility in steroid induced osteoporosis. Bone. 2016;84:15-24 pubmed publisher
..These findings provide a clear quantitative demonstration of how bone quality changes increase macroscopic fragility in secondary osteoporosis. ..