Kerstin J Rolfe

Summary

Affiliation: Mount Vernon Hospital
Country: UK

Publications

  1. doi request reprint Transforming growth factor beta1 signalling, wound healing and repair: a multifunctional cytokine with clinical implications for wound repair, a delicate balance
    B R Klass
    The RAFT Institute, Mount Vernon Hospital, Middlesex, UK
    Postgrad Med J 85:9-14. 2009
  2. ncbi request reprint Differential gene expression in response to transforming growth factor-beta1 by fetal and postnatal dermal fibroblasts
    Kerstin J Rolfe
    RAFT Institute of Plastic Surgery, Mount Vernon Hospital, Northwood Middlesex, United Kingdom
    Wound Repair Regen 15:897-906. 2007
  3. pmc Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors
    Kerstin J Rolfe
    RAFT Institute of Plastic Surgery, Leopold Muller Building, Mount Vernon Hospital, Northwood Middlesex, UK
    BMC Dev Biol 7:124. 2007
  4. pmc TP53 mutations in vulval lichen sclerosus adjacent to squamous cell carcinoma of the vulva
    K J Rolfe
    University Department of Obstetrics and Gynaecology, Royal Free and University College Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK
    Br J Cancer 89:2249-53. 2003
  5. ncbi request reprint A role for TGF-beta1-induced cellular responses during wound healing of the non-scarring early human fetus?
    Kerstin J Rolfe
    RAFT Institute of Plastic Surgery, Leopold Muller Building, Mount Vernon Hospital, Northwood Middlesex, UK
    J Invest Dermatol 127:2656-67. 2007
  6. doi request reprint The effect of epigallocatechin-3-gallate, a constituent of green tea, on transforming growth factor-beta1-stimulated wound contraction
    Benjamin R Klass
    The RAFT Institute, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom
    Wound Repair Regen 18:80-8. 2010
  7. ncbi request reprint The role of angiogenesis in vulvar cancer, vulvar intraepithelial neoplasia, and vulvar lichen sclerosus as determined by microvessel density analysis
    Jamna Saravanamuthu
    Department of Obstetrics and Gynaecology, Royal Free and University College Medical School Royal Free Campus, University College London, Rowland Hill Street, UK
    Gynecol Oncol 89:251-8. 2003
  8. ncbi request reprint Cyclin D1 and retinoblastoma protein in vulvar cancer and adjacent lesions
    K J Rolfe
    Department of Obstetrics and Gynaecology, Royal Free and University College Medical School, Royal Free Campus, London, United Kingdom
    Int J Gynecol Cancer 11:381-6. 2001
  9. ncbi request reprint Is localized, provoked vulvodynia an inflammatory condition?
    Lois J Eva
    Department of Obstetrics and Gynecology, Royal Free and University College Medical School, Royal Free Campus, London, UK
    J Reprod Med 52:379-84. 2007
  10. ncbi request reprint The effect of topical corticosteroids on Ki67 and p53 expression in vulval lichen sclerosus
    K J Rolfe
    Department of Obstetrics and Gynaecology, Royal Free and University College Medical School Royal Free Campus, Rowland Hill Street, London NW3 2PF, U K
    Br J Dermatol 147:503-8. 2002

Collaborators

Detail Information

Publications12

  1. doi request reprint Transforming growth factor beta1 signalling, wound healing and repair: a multifunctional cytokine with clinical implications for wound repair, a delicate balance
    B R Klass
    The RAFT Institute, Mount Vernon Hospital, Middlesex, UK
    Postgrad Med J 85:9-14. 2009
    ..This review focuses on TGFbeta1 signalling and the role that TGFbeta1 plays in wound healing, repair and scarring...
  2. ncbi request reprint Differential gene expression in response to transforming growth factor-beta1 by fetal and postnatal dermal fibroblasts
    Kerstin J Rolfe
    RAFT Institute of Plastic Surgery, Mount Vernon Hospital, Northwood Middlesex, United Kingdom
    Wound Repair Regen 15:897-906. 2007
    ..These developmentally related differences in fibroblast response to TGF-beta1 may influence wound-healing outcome, i.e., perfect regeneration or fibrosis...
  3. pmc Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors
    Kerstin J Rolfe
    RAFT Institute of Plastic Surgery, Leopold Muller Building, Mount Vernon Hospital, Northwood Middlesex, UK
    BMC Dev Biol 7:124. 2007
    ....
  4. pmc TP53 mutations in vulval lichen sclerosus adjacent to squamous cell carcinoma of the vulva
    K J Rolfe
    University Department of Obstetrics and Gynaecology, Royal Free and University College Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK
    Br J Cancer 89:2249-53. 2003
    ..The type of mutation detected is more likely to occur due to endogenous cellular changes rather than exogenous carcinogen exposure...
  5. ncbi request reprint A role for TGF-beta1-induced cellular responses during wound healing of the non-scarring early human fetus?
    Kerstin J Rolfe
    RAFT Institute of Plastic Surgery, Leopold Muller Building, Mount Vernon Hospital, Northwood Middlesex, UK
    J Invest Dermatol 127:2656-67. 2007
    ..These altered responses to TGF-beta1 may well contribute to the transition between perfect regeneration and scar formation seen during development...
  6. doi request reprint The effect of epigallocatechin-3-gallate, a constituent of green tea, on transforming growth factor-beta1-stimulated wound contraction
    Benjamin R Klass
    The RAFT Institute, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom
    Wound Repair Regen 18:80-8. 2010
    ....
  7. ncbi request reprint The role of angiogenesis in vulvar cancer, vulvar intraepithelial neoplasia, and vulvar lichen sclerosus as determined by microvessel density analysis
    Jamna Saravanamuthu
    Department of Obstetrics and Gynaecology, Royal Free and University College Medical School Royal Free Campus, University College London, Rowland Hill Street, UK
    Gynecol Oncol 89:251-8. 2003
    ....
  8. ncbi request reprint Cyclin D1 and retinoblastoma protein in vulvar cancer and adjacent lesions
    K J Rolfe
    Department of Obstetrics and Gynaecology, Royal Free and University College Medical School, Royal Free Campus, London, United Kingdom
    Int J Gynecol Cancer 11:381-6. 2001
    ..Cyclin D1 and pRb are separately involved in the progression of vulvar cancer, and changes in the expression of these proteins may represent an early stage of malignant transformation in vulvar disease...
  9. ncbi request reprint Is localized, provoked vulvodynia an inflammatory condition?
    Lois J Eva
    Department of Obstetrics and Gynecology, Royal Free and University College Medical School, Royal Free Campus, London, UK
    J Reprod Med 52:379-84. 2007
    ..To perform a pilot study to investigate the relationship between localized, provoked vulvodynia of the vestibule and inflammatory cytokine expression...
  10. ncbi request reprint The effect of topical corticosteroids on Ki67 and p53 expression in vulval lichen sclerosus
    K J Rolfe
    Department of Obstetrics and Gynaecology, Royal Free and University College Medical School Royal Free Campus, Rowland Hill Street, London NW3 2PF, U K
    Br J Dermatol 147:503-8. 2002
    ..Topical corticosteroids have become the treatment of choice for genital lichen sclerosus (LS) and are believed to be required for long-term relief of symptoms...
  11. ncbi request reprint Is there a link between vulval cancer and blood group?
    K J Rolfe
    University Department of Obstetrics and Gynaecology, Royal Free and University College Medical School, London, UK
    Eur J Gynaecol Oncol 23:111-2. 2002
    ..Our results suggest that blood group A is prevalent in patients with SCC associated with NNEDV but not in those women with squamous vulval cancer and associated VIN...
  12. ncbi request reprint The role of vascular endothelial growth factor-A (VEGF-A) and platelet-derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP) in Paget's disease of the vulva and breast
    Patricia E Ellis
    Department of Obstetrics and Gynaecology, Royal Free and University College Medical School, London, UK
    Anticancer Res 22:857-61. 2002
    ..Platelet-derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP) has also been shown to stimulate angiogenesis...