David J Griffiths

Summary

Affiliation: Moredun Research Institute
Country: UK

Publications

  1. ncbi Pathology and pathogenesis of ovine pulmonary adenocarcinoma
    D J Griffiths
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 0PZ, Scotland, UK
    J Comp Pathol 142:260-83. 2010
  2. ncbi Jaagsiekte sheep retrovirus is present at high concentration in lung fluid produced by ovine pulmonary adenocarcinoma-affected sheep and can survive for several weeks at ambient temperatures
    Christina Cousens
    Moredun Research Institute, Pentlands Science Park, Edinburgh EH26 0PZ, UK
    Res Vet Sci 87:154-6. 2009
  3. ncbi Jaagsiekte sheep retrovirus infects multiple cell types in the ovine lung
    Henny M Martineau
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 OPZ, United Kingdom
    J Virol 85:3341-55. 2011
  4. ncbi Infestation of sheep with Psoroptes ovis, the sheep scab mite, results in recruitment of Foxp3(+) T cells into the dermis
    T N McNeilly
    Moredun Research Institute, Pentlands Science Park, Bush Loan Penicuik, Midlothian, EH26 OPZ, UK
    Parasite Immunol 32:361-9. 2010
  5. ncbi Jaagsiekte sheep retrovirus-specific immune responses induced by vaccination: a comparison of immunisation strategies
    Christina Summers
    Medical Microbiology, University of Edinburgh, Scotland, UK
    Vaccine 24:1821-9. 2006

Collaborators

Detail Information

Publications5

  1. ncbi Pathology and pathogenesis of ovine pulmonary adenocarcinoma
    D J Griffiths
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 0PZ, Scotland, UK
    J Comp Pathol 142:260-83. 2010
    ..The recent advances in understanding JSRV and the pathogenesis of OPA should lead to novel strategies for diagnosis and control of this disease and for its exploitation as a comparative model for human lung cancer...
  2. ncbi Jaagsiekte sheep retrovirus is present at high concentration in lung fluid produced by ovine pulmonary adenocarcinoma-affected sheep and can survive for several weeks at ambient temperatures
    Christina Cousens
    Moredun Research Institute, Pentlands Science Park, Edinburgh EH26 0PZ, UK
    Res Vet Sci 87:154-6. 2009
    ..These are the first quantitative data on JSRV in lung fluid and provide valuable information for implementing appropriate biosecurity measures to control the spread of JSRV in the field...
  3. ncbi Jaagsiekte sheep retrovirus infects multiple cell types in the ovine lung
    Henny M Martineau
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 OPZ, United Kingdom
    J Virol 85:3341-55. 2011
    ..These results enhance the understanding of OPA pathogenesis and may have comparative relevance to human lung cancer, for which samples representing early stages of tumor growth are difficult to obtain...
  4. ncbi Infestation of sheep with Psoroptes ovis, the sheep scab mite, results in recruitment of Foxp3(+) T cells into the dermis
    T N McNeilly
    Moredun Research Institute, Pentlands Science Park, Bush Loan Penicuik, Midlothian, EH26 OPZ, UK
    Parasite Immunol 32:361-9. 2010
    ..Future work will investigate the regulatory function of ovine Foxp3(+) T cells and determine whether the quality of the Treg response to P. ovis plays a role in individual susceptibility to the mite...
  5. ncbi Jaagsiekte sheep retrovirus-specific immune responses induced by vaccination: a comparison of immunisation strategies
    Christina Summers
    Medical Microbiology, University of Edinburgh, Scotland, UK
    Vaccine 24:1821-9. 2006
    ..These results will help in the design of a protective vaccine against JSRV infection and the development of OPA...