Laura E McNamara

Summary

Country: UK

Publications

  1. pmc Metabolomics: a valuable tool for stem cell monitoring in regenerative medicine
    Laura E McNamara
    Centre for Cell Engineering, Division of Molecular, Cell, and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    J R Soc Interface 9:1713-24. 2012
  2. doi request reprint The role of microtopography in cellular mechanotransduction
    Laura E McNamara
    Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, UK
    Biomaterials 33:2835-47. 2012
  3. doi request reprint Skeletal stem cell physiology on functionally distinct titania nanotopographies
    Laura E McNamara
    Centre for Cell Engineering, School of Molecular, Cell and Systems Biology, University of Glasgow, Glasgow G12 8QQ, UK
    Biomaterials 32:7403-10. 2011
  4. doi request reprint Preventing and troubleshooting artefacts in saturation labelled fluorescence 2-D difference gel electrophoresis (saturation DiGE)
    Laura E McNamara
    Centre for Cell Engineering, Division of Biochemistry and Cell Biology, Joseph Black Building, University of Glasgow, Glasgow, UK
    Proteomics 11:4610-21. 2011
  5. pmc Fluorescence two-dimensional difference gel electrophoresis for biomaterial applications
    Laura E McNamara
    Centre for Cell Engineering, University of Glasgow, Glasgow G12 8QQ, UK
    J R Soc Interface 7:S107-18. 2010
  6. doi request reprint Biomimetic microtopography to enhance osteogenesis in vitro
    Andrew Wilkinson
    Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, UK
    Acta Biomater 7:2919-25. 2011
  7. doi request reprint Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency
    Rebecca J McMurray
    Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK
    Nat Mater 10:637-44. 2011
  8. pmc Nanotopographical control of stem cell differentiation
    Laura E McNamara
    Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland
    J Tissue Eng 2010:120623. 2010
  9. doi request reprint The use of microarrays and fluorescence in situ hybridization for the study of mechanotransduction from topography
    Laura E McNamara
    Centre for Cell Engineering, Institute of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
    Methods Cell Biol 119:293-309. 2014

Collaborators

Detail Information

Publications9

  1. pmc Metabolomics: a valuable tool for stem cell monitoring in regenerative medicine
    Laura E McNamara
    Centre for Cell Engineering, Division of Molecular, Cell, and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    J R Soc Interface 9:1713-24. 2012
    ..Case studies are used to illustrate key points, focusing on the use of metabolomics in the examination of mesenchymal stem cell responses to titania-nanopillared substrata designed for orthopaedic applications...
  2. doi request reprint The role of microtopography in cellular mechanotransduction
    Laura E McNamara
    Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, UK
    Biomaterials 33:2835-47. 2012
    ....
  3. doi request reprint Skeletal stem cell physiology on functionally distinct titania nanotopographies
    Laura E McNamara
    Centre for Cell Engineering, School of Molecular, Cell and Systems Biology, University of Glasgow, Glasgow G12 8QQ, UK
    Biomaterials 32:7403-10. 2011
    ..These studies illustrate the potential for clinically relevant titania nanopillared substrata to modulate MSCs, with implications for orthopaedic device design and application...
  4. doi request reprint Preventing and troubleshooting artefacts in saturation labelled fluorescence 2-D difference gel electrophoresis (saturation DiGE)
    Laura E McNamara
    Centre for Cell Engineering, Division of Biochemistry and Cell Biology, Joseph Black Building, University of Glasgow, Glasgow, UK
    Proteomics 11:4610-21. 2011
    ..In this paper, measures to prevent and troubleshoot artefacts in the saturation DiGE workflow are discussed, with illustration of some examples as they may be encountered in gel images or analysis...
  5. pmc Fluorescence two-dimensional difference gel electrophoresis for biomaterial applications
    Laura E McNamara
    Centre for Cell Engineering, University of Glasgow, Glasgow G12 8QQ, UK
    J R Soc Interface 7:S107-18. 2010
    ..In this review, we consider the application of DiGE-both minimal and saturation labelling-to biomaterials research, considering the challenges and rewards of this approach...
  6. doi request reprint Biomimetic microtopography to enhance osteogenesis in vitro
    Andrew Wilkinson
    Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, UK
    Acta Biomater 7:2919-25. 2011
    ..The results further demonstrate the potential for biomimicry in material design and show that the osteoblast response can be tuned from changes in feature size...
  7. doi request reprint Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency
    Rebecca J McMurray
    Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK
    Nat Mater 10:637-44. 2011
    ..Furthermore, the study implicates a role for small RNAs in repressing key cell signalling and metabolomic pathways, demonstrating the potential of surfaces as non-invasive tools with which to address the stem cell niche...
  8. pmc Nanotopographical control of stem cell differentiation
    Laura E McNamara
    Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland
    J Tissue Eng 2010:120623. 2010
    ..Data from proteomic research is also outlined in relation to topography-mediated fate determination, as this approach provides insight into the global molecular changes at the level of the functional effectors...
  9. doi request reprint The use of microarrays and fluorescence in situ hybridization for the study of mechanotransduction from topography
    Laura E McNamara
    Centre for Cell Engineering, Institute of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
    Methods Cell Biol 119:293-309. 2014
    ..In this chapter, we describe the methodologies of these two techniques and provide technical tips that should help overcome challenges in carrying them out. ..