Richard McCulloch


Country: UK


  1. Marques C, Dickens N, Paape D, Campbell S, McCulloch R. Genome-wide mapping reveals single-origin chromosome replication in Leishmania, a eukaryotic microbe. Genome Biol. 2015;16:230 pubmed publisher
  2. Marques C, Tiengwe C, Lemgruber L, Damasceno J, Scott A, Paape D, et al. Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiation. Nucleic Acids Res. 2016;44:4763-84 pubmed publisher
    ..This work shows that ORC architecture and regulation are diverged features of DNA replication initiation in T. brucei, providing new insight into this key stage of eukaryotic genome copying. ..
  3. Devlin R, Marques C, McCulloch R. Does DNA replication direct locus-specific recombination during host immune evasion by antigenic variation in the African trypanosome?. Curr Genet. 2017;63:441-449 pubmed publisher
    ..Here, we discuss three emerging models for VSG switching initiation and ask how these compare with processes for adaptive genome change found in other organisms. ..

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