Amarjit Saini

Summary

Affiliation: Manchester Metropolitan University
Country: UK

Publications

  1. ncbi Beneficial synergistic interactions of TNF-alpha and IL-6 in C2 skeletal myoblasts--potential cross-talk with IGF system
    Nasser Al-Shanti
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Cheshire, England, UK
    Growth Factors 26:61-73. 2008
  2. ncbi Waste management - cytokines, growth factors and cachexia
    Amarjit Saini
    Institute for Biophysical and Clinical Research into Human Movement, Department of Exercise and Sport Science, Manchester Metropolitan University, Hassall Road, Alsager, Cheshire ST7 2HL, England, UK
    Cytokine Growth Factor Rev 17:475-86. 2006
  3. ncbi Pro- and anti-apoptotic roles for IGF-I in TNF-alpha-induced apoptosis: a MAP kinase mediated mechanism
    Amarjit Saini
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Cheshire, UK
    Growth Factors 26:239-53. 2008
  4. ncbi Powerful signals for weak muscles
    Amarjit Saini
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, United Kingdom
    Ageing Res Rev 8:251-67. 2009
  5. ncbi C2 skeletal myoblast survival, death, proliferation and differentiation: regulation by Adra1d
    Amarjit Saini
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, M1 5GD, UK
    Cell Physiol Biochem 25:253-62. 2010
  6. ncbi Sirtuin 1 regulates skeletal myoblast survival and enhances differentiation in the presence of resveratrol
    Amarjit Saini
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Oxford Road, Manchester M1 5GD, UK
    Exp Physiol 97:400-18. 2012
  7. ncbi A semi-automated programme for tracking myoblast migration following mechanical damage: manipulation by chemical inhibitors
    Nasser Al-Shanti
    School of Healthcare Science, Institute for Biomedical Research into Human Movement and Health IRM, MMU, Oxford Road, Manchester, UK
    Cell Physiol Biochem 27:625-36. 2011
  8. ncbi Two-Step versus One-Step RNA-to-CT 2-Step and One-Step RNA-to-CT 1-Step: validity, sensitivity, and efficiency
    Nasser Al-Shanti
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, M1 5GD, United Kingdom
    J Biomol Tech 20:172-9. 2009
  9. ncbi Adult stem cells: the therapeutic potential of skeletal muscle
    Amarjit Saini
    Institute for Biophysical and Clinical Research into Human Movement, Department of Exercise and Sport Science, Manchester Metropolitan University, Hassall Road, Alsager, Cheshire ST7 2HL, England, UK
    Curr Stem Cell Res Ther 1:157-71. 2006
  10. ncbi Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo
    Jatin G Burniston
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Webster Street, Liverpool L3 2ET, UK
    J Mol Cell Cardiol 39:395-9. 2005

Collaborators

Detail Information

Publications10

  1. ncbi Beneficial synergistic interactions of TNF-alpha and IL-6 in C2 skeletal myoblasts--potential cross-talk with IGF system
    Nasser Al-Shanti
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Cheshire, England, UK
    Growth Factors 26:61-73. 2008
    ..Our data suggest that in the presence of TNF-alpha/IL-6 functions positively and potentially also cooperatively with the IGF system to achieve the maximal beneficial effect on skeletal myoblast numbers...
  2. ncbi Waste management - cytokines, growth factors and cachexia
    Amarjit Saini
    Institute for Biophysical and Clinical Research into Human Movement, Department of Exercise and Sport Science, Manchester Metropolitan University, Hassall Road, Alsager, Cheshire ST7 2HL, England, UK
    Cytokine Growth Factor Rev 17:475-86. 2006
    ....
  3. ncbi Pro- and anti-apoptotic roles for IGF-I in TNF-alpha-induced apoptosis: a MAP kinase mediated mechanism
    Amarjit Saini
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Cheshire, UK
    Growth Factors 26:239-53. 2008
    ....
  4. ncbi Powerful signals for weak muscles
    Amarjit Saini
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, United Kingdom
    Ageing Res Rev 8:251-67. 2009
    ....
  5. ncbi C2 skeletal myoblast survival, death, proliferation and differentiation: regulation by Adra1d
    Amarjit Saini
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, M1 5GD, UK
    Cell Physiol Biochem 25:253-62. 2010
    ..Adra1d knockdown resulted in significantly higher levels of cell death under all incubations suggesting Adra1d expression is essential for skeletal muscle cell survival...
  6. ncbi Sirtuin 1 regulates skeletal myoblast survival and enhances differentiation in the presence of resveratrol
    Amarjit Saini
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Oxford Road, Manchester M1 5GD, UK
    Exp Physiol 97:400-18. 2012
    ..05 and 12.78 ± 4.52%, P = 0.054) by resveratrol, which also significantly rescued the block on differentiation. In conclusion, Sirt1 expression increases in conditons of stress, potentially serving to reduce or dampen myoblast death...
  7. ncbi A semi-automated programme for tracking myoblast migration following mechanical damage: manipulation by chemical inhibitors
    Nasser Al-Shanti
    School of Healthcare Science, Institute for Biomedical Research into Human Movement and Health IRM, MMU, Oxford Road, Manchester, UK
    Cell Physiol Biochem 27:625-36. 2011
    ..We hypothesised that damaged skeletal myoblasts would elicit a mesenchymal-like migratory response, which could be precisely tracked and subsequently manipulated...
  8. ncbi Two-Step versus One-Step RNA-to-CT 2-Step and One-Step RNA-to-CT 1-Step: validity, sensitivity, and efficiency
    Nasser Al-Shanti
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, M1 5GD, United Kingdom
    J Biomol Tech 20:172-9. 2009
    ..This is the first study to demonstrate that the RNA-to-C(T) 2-Step kit is not reliable to be performed as a one-step reaction but as a two-step reaction, is even more sensitive than the newly launched RNA-to-C(T) 1-Step kit...
  9. ncbi Adult stem cells: the therapeutic potential of skeletal muscle
    Amarjit Saini
    Institute for Biophysical and Clinical Research into Human Movement, Department of Exercise and Sport Science, Manchester Metropolitan University, Hassall Road, Alsager, Cheshire ST7 2HL, England, UK
    Curr Stem Cell Res Ther 1:157-71. 2006
    ..In this review, current understanding of the different stem cells within muscle will be discussed as will their potential utility for regenerative medicine...
  10. ncbi Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo
    Jatin G Burniston
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Webster Street, Liverpool L3 2ET, UK
    J Mol Cell Cardiol 39:395-9. 2005
    ..High circulating levels of aldosterone are clearly capable of damaging all types of striated muscle and this may lend support to the concept that heart failure is a generalised, rather than cardiac-specific, myopathy...