H Degens

Summary

Affiliation: Manchester Metropolitan University
Country: UK

Publications

  1. pmc Relationship between ventilatory function and age in master athletes and a sedentary reference population
    Hans Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building Chester Street, Manchester, M1 5GD, UK
    Age (Dordr) 35:1007-15. 2013
  2. doi request reprint Factors contributing to the variability in muscle ageing
    Hans Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, United Kingdom
    Maturitas 73:197-201. 2012
  3. ncbi request reprint Control of muscle size during disuse, disease, and aging
    H Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    Int J Sports Med 27:94-9. 2006
  4. ncbi request reprint Maintenance of heterogeneity of capillary spacing is essential for adequate oxygenation in the soleus muscle of the growing rat
    Hans Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    Microcirculation 13:467-76. 2006
  5. doi request reprint Changes in contractile properties of skinned single rat soleus and diaphragm fibres after chronic hypoxia
    Hans Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester, M1 5GD, UK
    Pflugers Arch 460:863-73. 2010
  6. doi request reprint The role of systemic inflammation in age-related muscle weakness and wasting
    H Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester M1 5GD, UK
    Scand J Med Sci Sports 20:28-38. 2010
  7. ncbi request reprint Apoptosis and Id2 expression in diaphragm and soleus muscle from the emphysematous hamster
    Hans Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    Am J Physiol Regul Integr Comp Physiol 293:R135-44. 2007
  8. ncbi request reprint Application of skinned single muscle fibres to determine myofilament function in ageing and disease
    H Degens
    Institute for Clinical and Biophysical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    J Musculoskelet Neuronal Interact 7:56-61. 2007
  9. ncbi request reprint Disproportionate changes in skeletal muscle strength and size with resistance training and ageing
    H Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester M1 5GD, UK
    J Musculoskelet Neuronal Interact 9:123-9. 2009
  10. ncbi request reprint Acute hypoxia limits endurance but does not affect muscle contractile properties
    Hans Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Hassall Road, Alsager, Chesire ST7 2HL, United Kingdom
    Muscle Nerve 33:532-7. 2006

Detail Information

Publications57

  1. pmc Relationship between ventilatory function and age in master athletes and a sedentary reference population
    Hans Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building Chester Street, Manchester, M1 5GD, UK
    Age (Dordr) 35:1007-15. 2013
    ..Life-long exercise does not appear to attenuate the age-related decrease in ventilatory function. The better respiratory function in master athletes than age-matched sedentary people might be due to self-selection and attrition bias...
  2. doi request reprint Factors contributing to the variability in muscle ageing
    Hans Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, United Kingdom
    Maturitas 73:197-201. 2012
    ..Finally, it is suggested that age-related alterations in the capillary bed may negatively affect muscle mass...
  3. ncbi request reprint Control of muscle size during disuse, disease, and aging
    H Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    Int J Sports Med 27:94-9. 2006
    ....
  4. ncbi request reprint Maintenance of heterogeneity of capillary spacing is essential for adequate oxygenation in the soleus muscle of the growing rat
    Hans Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    Microcirculation 13:467-76. 2006
    ..It is not known, however, how the capillary distribution is affected and what impact it has on the oxygenation of the muscle...
  5. doi request reprint Changes in contractile properties of skinned single rat soleus and diaphragm fibres after chronic hypoxia
    Hans Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester, M1 5GD, UK
    Pflugers Arch 460:863-73. 2010
    ..These effects are similar in the soleus and diaphragm muscle, but more pronounced in type IIa than I fibres...
  6. doi request reprint The role of systemic inflammation in age-related muscle weakness and wasting
    H Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester M1 5GD, UK
    Scand J Med Sci Sports 20:28-38. 2010
    ..Thus, the negative effect of systemic inflammation on muscle strength at old age may only become apparent when it exceeds a certain threshold and persists for a prolonged period...
  7. ncbi request reprint Apoptosis and Id2 expression in diaphragm and soleus muscle from the emphysematous hamster
    Hans Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    Am J Physiol Regul Integr Comp Physiol 293:R135-44. 2007
    ..These alterations may impair the regenerative capacity of skeletal muscles and ultimately contribute to muscle wasting...
  8. ncbi request reprint Application of skinned single muscle fibres to determine myofilament function in ageing and disease
    H Degens
    Institute for Clinical and Biophysical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    J Musculoskelet Neuronal Interact 7:56-61. 2007
    ..While muscle weakness experienced after surgery could not be explained by changes in specific tension or FCSA of individual fibres, the preparation revealed significant changes in myofilament function during ageing and COPD...
  9. ncbi request reprint Disproportionate changes in skeletal muscle strength and size with resistance training and ageing
    H Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester M1 5GD, UK
    J Musculoskelet Neuronal Interact 9:123-9. 2009
    ....
  10. ncbi request reprint Acute hypoxia limits endurance but does not affect muscle contractile properties
    Hans Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Hassall Road, Alsager, Chesire ST7 2HL, United Kingdom
    Muscle Nerve 33:532-7. 2006
    ..This indicates that skeletal muscle dysfunction during conditions associated with prolonged hypoxemia, except for limited endurance, is not due to acute effects of hypoxemia...
  11. ncbi request reprint Age-related skeletal muscle dysfunction: causes and mechanisms
    H Degens
    Institute for Clinical and Biophysical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Alsager, Cheshire, UK
    J Musculoskelet Neuronal Interact 7:246-52. 2007
    ..Moreover, muscle mass, strength and the response to strength training in old age are all inversely related to the degree of systemic inflammation...
  12. doi request reprint The time course of denervation-induced changes is similar in soleus muscles of adult and old rats
    Hans Degens
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Alsager, UK
    Appl Physiol Nutr Metab 33:299-308. 2008
    ..23%; old 1% vs. 13%; p < 0.05). Except for changes in capillarisation, the time course of atrophy and decrease in oxidative capacity following denervation was similar in soleus muscles from adult and old rats...
  13. doi request reprint Heterogeneity of capillary spacing in the hypertrophied plantaris muscle from young-adult and old rats
    Hans Degens
    Instititute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager, ST7 2HL, UK
    Adv Exp Med Biol 645:61-6. 2009
    ....
  14. ncbi request reprint Region-specific adaptations in determinants of rat skeletal muscle oxygenation to chronic hypoxia
    R C I Wüst
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, UK
    Am J Physiol Heart Circ Physiol 297:H364-74. 2009
    ..We conclude that the determinants of tissue oxygenation show region-specific adaptations, resulting in a marked differential effect on tissue Po(2)...
  15. doi request reprint Variation in the determinants of power of chemically skinned human muscle fibres
    S F Gilliver
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester M5 1GD, UK
    Exp Physiol 94:1070-8. 2009
    ..In searching for the causes of variation in peak power of fibres of the same type, it appears likely that there are two factors, one that affects P(0) and another that leads to variation in both V(max) and a/P(0)...
  16. ncbi request reprint Carbon monoxide inhalation reduces skeletal muscle fatigue resistance
    C I Morse
    Institute for Biophysical and Clinical Research into Human Movement IRM, Manchester Metropolitan University, Cheshire, UK
    Acta Physiol (Oxf) 192:397-401. 2008
    ..To determine whether inhalation of carbon monoxide (CO), resulting in carboxyhaemoglobin (COHb) levels observed in smokers, had an effect on muscle fatigue during electrically evoked and voluntary muscle contractions...
  17. ncbi request reprint Comparison of MRI and DXA to measure muscle size and age-related atrophy in thigh muscles
    T M Maden-Wilkinson
    School of Healthcare Science, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester, M1 5GD, United Kingdom
    J Musculoskelet Neuronal Interact 13:320-8. 2013
    ..Magnetic resonance imaging (MRI) and dual-energy x-ray absorptiometry (DXA) were used to examine the thigh lean mass in young and old men and women...
  18. ncbi request reprint Effects of alfacalcidol on the contractile properties of the gastrocnemius medialis muscle in adult and old rats
    J Testerink
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, United Kingdom
    J Physiol Pharmacol 62:111-8. 2011
    ..Weight loss was largely due to a reduced food intake, while the left shift in the force-frequency relation may be due to increased 1,25D levels...
  19. ncbi request reprint HIF1A P582S gene association with endurance training responses in young women
    J S McPhee
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building room 216, Oxford Road, Manchester, M1 5GD, UK
    Eur J Appl Physiol 111:2339-47. 2011
    ..In a sub-group we also provide preliminary evidence of differential muscle metabolic adaptations between genotypes...
  20. doi request reprint Effects of submaximal activation on the determinants of power of chemically skinned rat soleus fibres
    S F Gilliver
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester, UK
    Exp Physiol 96:171-8. 2011
    ..The fact that V(max) (and thus g(2)) changed to a greater extent than k(tr) (f(app) + g(app)) is the reason that reduced activation results in a reduction in curvature of the force-velocity relationship...
  21. ncbi request reprint Muscle fatigue resistance during stimulated contractions is reduced in young male smokers
    C I Morse
    Institute for Biophysical and Clinical Research into Human Movement IRM, Manchester Metropolitan University, Cheshire, UK
    Acta Physiol (Oxf) 191:123-9. 2007
    ..To determine whether muscle function is compromised in healthy smokers in comparison with activity-matched non-smokers...
  22. pmc The acute effect of stretching on the passive stiffness of the human gastrocnemius muscle tendon unit
    C I Morse
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager Campus, Hassall Road, Alsager, Cheshire, UK
    J Physiol 586:97-106. 2008
    ....
  23. ncbi request reprint Resistance training increases in vivo quadriceps femoris muscle specific tension in young men
    R M Erskine
    Faculty of Science and Engineering, Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, UK
    Acta Physiol (Oxf) 199:83-9. 2010
    ..The present study investigated whether in vivo human quadriceps femoris (QF) muscle specific tension changed following strength training by systematically determining QF maximal force and physiological cross-sectional area (PCSA)...
  24. ncbi request reprint Effects of smoking on tibial and radial bone mass and strength may diminish with age
    Rob C I Wüst
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester M1 5GD, United Kingdom
    J Clin Endocrinol Metab 95:2763-71. 2010
    ..The purpose of the study was to assess the effect of cigarette smoking on indicators of bone strength across a wide age range, controlling for physical activity and neuromuscular performance...
  25. ncbi request reprint Comparison of MRI and DXA to measure muscle size and age-related atrophy in thigh muscles
    T M Maden-Wilkinson
    School of Healthcare Science, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester, United Kingdom
    J Musculoskelet Neuronal Interact 13:320-8. 2013
    ..Magnetic resonance imaging (MRI) and dual-energy x-ray absorptiometry (DXA) were used to examine the thigh lean mass in young and old men and women...
  26. pmc Thigh muscle volume in relation to age, sex and femur volume
    T M Maden-Wilkinson
    Institute for Research into Human Movement and Health, School of Healthcare Science, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester, M1 5GD, UK
    Age (Dordr) 36:383-93. 2014
    ..The quadriceps seems relatively more affected by ageing than other thigh muscles. ..
  27. ncbi request reprint Recruitment of single muscle fibers during submaximal cycling exercise
    T M Altenburg
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Cheshire, United Kingdom
    J Appl Physiol (1985) 103:1752-6. 2007
    ..Furthermore, the PCr/Cr ratio method is more sensitive in determining fiber activation than the PAS stain intensity method...
  28. doi request reprint Variability in the magnitude of response of metabolic enzymes reveals patterns of co-ordinated expression following endurance training in women
    J S McPhee
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, UK
    Exp Physiol 96:699-707. 2011
    ..Differences between individuals in the magnitude of response might reflect the influence of environmental and genetic factors that govern training adaptations...
  29. ncbi request reprint Improvements in muscle-tendon properties are beneficial to balance in multiple sclerosis
    G L N Onambélé
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Hassall Road, Alsager, Stoke on Trent, ST7 2HL, UK
    Mult Scler 12:666-9. 2006
    ..We concluded that improvements in muscle-tendon properties were accompanied by improved balance and a general feeling of well-being after training...
  30. ncbi request reprint The validity of estimating quadriceps volume from single MRI cross-sections in young men
    Christopher I Morse
    Institute for Biophysical and Clinical Research into Human Movement IRM, Manchester Metropolitan University, Alsager Campus, Hassall Road, Alsager, Cheshire ST7 2HL, UK
    Eur J Appl Physiol 100:267-74. 2007
    ..95 (P < 0.01) and SEE = 4.5 +/- 2.7%]. Substituting ACSA from a single MRI scan at 60% of femur length into a previously determined regression equation allows for an estimation of muscle volume with a 10% error of estimate...
  31. ncbi request reprint Muscle tissue oxygenation and VEGF in VO-matched vibration and squatting exercise
    Jörn Rittweger
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, UK
    Clin Physiol Funct Imaging 30:269-78. 2010
    ..Most likely, the transient response is because of local vascular regulatory mechanisms and due to muscle contraction mechanics. This might become clinically relevant under pathological conditions, e.g. in vascular disorders...
  32. pmc Skeletal muscle properties and fatigue resistance in relation to smoking history
    Rob C I Wüst
    Institute for Biomedical Research into Human Movement and Health IRM, Manchester Metropolitan University, John Dalton Building, Chester Street, Manchester, UK
    Eur J Appl Physiol 104:103-10. 2008
    ..An acute and reversible effect of smoking could be caused by carbon monoxide and/or other substances in smoke hampering oxygen delivery and mitochondrial function...
  33. ncbi request reprint In vivo specific tension of the human quadriceps femoris muscle
    Robert M Erskine
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester, M1 5GD, UK
    Eur J Appl Physiol 106:827-38. 2009
    ..Furthermore, a simple method of estimating QF specific tension provided similar values to the comprehensive approach, thereby enabling accurate estimations of QF specific tension where time and resources are limited...
  34. pmc Factors contributing to muscle wasting and dysfunction in COPD patients
    Rob C I Wüst
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Cheshire, United Kingdom
    Int J Chron Obstruct Pulmon Dis 2:289-300. 2007
    ..Finally, we briefly discuss the various treatments and rehabilitation strategies available to control muscle wasting and fatigue in patients with COPD...
  35. doi request reprint Fiber capillary supply related to fiber size and oxidative capacity in human and rat skeletal muscle
    Rob C I Wüst
    Instititute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Alsager, ST7 2HL, UK
    Adv Exp Med Biol 645:75-80. 2009
    ..e. whether it came from the deep or superficial region of the muscle (all P < 0.001) and not SDH. In conclusion, size, type and metabolic surrounding rather than mitochondrial activity determine the capillary supply to a muscle fiber...
  36. ncbi request reprint Sex differences in contractile properties and fatigue resistance of human skeletal muscle
    Rob C I Wüst
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Chester Street, Manchester, M1 5GD, UK
    Exp Physiol 93:843-50. 2008
    ....
  37. ncbi request reprint Skeletal muscle capillarization and oxidative metabolism in healthy smokers
    Rob C I Wüst
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Chester Street, Manchester, M1 5 GD, UK
    Appl Physiol Nutr Metab 33:1240-5. 2008
    ..93; p = 0.02) is absent in smokers. This indicates that the lower muscle fatigue resistance of smokers can likely be attributed to causes other than differences in oxidative metabolism and capillarization...
  38. ncbi request reprint Inter-individual variability in adaptation of the leg muscles following a standardised endurance training programme in young women
    Jamie S McPhee
    Institute for Biomedical Research into Human Movement and Health IRM, Manchester Metropolitan University, John Dalton Building room 310, Oxford Road, Manchester, M1 5GD, UK
    Eur J Appl Physiol 109:1111-8. 2010
    ....
  39. doi request reprint Diffusion capacity of the lung in young and old endurance athletes
    H Degens
    Institute for Biophysical and Clinical Research into Human Movement, Manchester Metropolitan University, Manchester, United Kingdom
    Int J Sports Med 34:1051-7. 2013
    ..However, the diffusion capacity of the older athlete is lower than that of the young non-athlete. ..
  40. ncbi request reprint Effects of oxidation on the power of chemically skinned rat soleus fibres
    S F Gilliver
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester M5 1GD, UK
    J Musculoskelet Neuronal Interact 10:267-73. 2010
    ..This suggests that oxidative modification is a possible cause of the variation in contractile properties between muscle fibres of the same type...
  41. doi request reprint Effects of age and starting age upon side asymmetry in the arms of veteran tennis players: a cross-sectional study
    A Ireland
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Chester Street, Manchester, M1 5GD, UK
    Osteoporos Int 25:1389-400. 2014
    ..Large side asymmetries in bone strength were found in veteran players, which were more pronounced in men, younger players and childhood starters...
  42. ncbi request reprint Side-to-side differences in bone strength in master jumpers and sprinters
    A Ireland
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, United Kingdom
    J Musculoskelet Neuronal Interact 11:298-305. 2011
    ....
  43. ncbi request reprint Is the myonuclear domain size fixed?
    S F T Van der Meer
    Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, John Dalton Building, Chester Street, Manchester M1 5GD, United Kingdom
    J Musculoskelet Neuronal Interact 11:286-97. 2011
    ..It also suggests that only when the myonuclear domain size exceeds a certain threshold during growth or overload-induced hypertrophy acquisition of new myonuclei is required for further fibre hypertrophy...
  44. doi request reprint The acute effect of different warm-up protocols on anaerobic performance in elite youth soccer players
    Robert A Needham
    Exercise and Sport Science Department, Manchester Metropolitan University, Alsager, Manchester, United Kingdom
    J Strength Cond Res 23:2614-20. 2009
    ..In addition, a dynamic warm-up produces a superior sprint and jump performance compared to a warm-up consisting of static stretching...
  45. ncbi request reprint Capillarization in skeletal muscle of rats with cardiac hypertrophy
    Hans Degens
    Department of Anatomy, University of South Florida, Tampa, FL 33612, USA
    Med Sci Sports Exerc 34:258-66. 2002
    ..We assessed changes in capillary supply in plantaris and diaphragm muscles of a rat aorta-caval fistula (ACF) preparation, a volume overload model for CHF...
  46. ncbi request reprint Potential role for Id myogenic repressors in apoptosis and attenuation of hypertrophy in muscles of aged rats
    Stephen E Alway
    Laboratory of Muscle, Sarcopenia, and Muscle Diseases, Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia 26506, USA
    Am J Physiol Cell Physiol 283:C66-76. 2002
    ..These data are consistent with the hypothesis that aging increases Id transcripts that activate apoptotic pathways involving BAX. This may contribute to sarcopenia by attenuating MRF protein levels in muscles of old animals...
  47. ncbi request reprint Skeletal muscle function and hypertrophy are diminished in old age
    Hans Degens
    Department of Physiology 237, University of Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Muscle Nerve 27:339-47. 2003
    ..001). Thus, aging is associated with a decline in muscle mass and function. In addition, at advanced age, the hypertrophic response is reduced and a hypertrophic stimulus even aggravates the age-associated muscle weakening...
  48. pmc Diaphragm dysfunction in chronic obstructive pulmonary disease
    Coen A C Ottenheijm
    Department of Pulmonary Diseases, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Am J Respir Crit Care Med 172:200-5. 2005
    ..However, the pathophysiology of failure of the diaphragm to generate force in COPD is in part unclear...
  49. doi request reprint Muscle function in smokers: clearing up the smoke
    Rob C I Wüst
    Chest 134:219-20; author reply 220. 2008
  50. pmc Increased myogenic repressor Id mRNA and protein levels in hindlimb muscles of aged rats
    Stephen E Alway
    Laboratory of Muscle, Sarcopenia, and Muscle Diseases, Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia 26506 9227, USA
    Am J Physiol Regul Integr Comp Physiol 282:R411-22. 2002
    ..05) in hindlimb muscles of aged rats compared with young adult rats. The elevated levels of Id mRNA and protein suggest that MRF repressors may play a role in gene regulation of fast and slow muscles in aged rats...
  51. ncbi request reprint Vascular endothelial growth factor, capillarization, and function of the rat plantaris muscle at the onset of hypertrophy
    Hans Degens
    Department of Physiology 237, University Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Jpn J Physiol 53:181-91. 2003
    ....
  52. ncbi request reprint Denervation stimulates apoptosis but not Id2 expression in hindlimb muscles of aged rats
    Stephen E Alway
    Laboratory of Muscle, Sarcopenia and Muscle Diseases, Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown 26506 9227, USA
    J Gerontol A Biol Sci Med Sci 58:687-97. 2003
    ..The elevated Id expression in muscles from aged animals is therefore not a direct consequence of loss of alpha-motoneurons during senescence...
  53. ncbi request reprint Capillarization and vascular endothelial growth factor expression in hypertrophying anterior latissimus dorsi muscle of the Japanese quail
    Hans Degens
    Dept Physiology, University of Nijmegen, 6500 HB Nijmegen, The Netherlands
    Adv Exp Med Biol 530:577-85. 2003
    ..The absence of any significant change in VEGF mRNA levels indicates that increased levels of VEGF mRNA are not crucial for capillary proliferation during muscle hypertrophy...
  54. ncbi request reprint Cardiac fatty acid metabolism is preserved in the compensated hypertrophic rat heart
    Hans Degens
    Dep of Physiology, Cardiovascular Research Institute Maastricht CARIM Maastricht University, 616, 6200 MD Maastricht, The Netherlands
    Basic Res Cardiol 101:17-26. 2006
    ..These findings indicate that cardiac FA oxidative capacity is preserved during compensatory hypertrophy, and that a decline in metabolic gene expression does not represent a hallmark of the development of hypertrophy...
  55. ncbi request reprint A dynamic extensor brace reduces electromyographic activity of wrist extensor muscles in patients with lateral epicondylalgia
    Miriam Faes
    Department of Physiology, University Medical Centre, Nijmegen, The Netherlands
    J Orthop Sports Phys Ther 36:170-8. 2006
    ..Semiexperimental study...
  56. ncbi request reprint The application of an external wrist extension force reduces electromyographic activity of wrist extensor muscles during gripping
    Niek van Elk
    Department of Physiology, University Medical Center, Nijmegen, The Netherlands
    J Orthop Sports Phys Ther 34:228-34. 2004
    ..Experimental repeated-measures study...
  57. ncbi request reprint Effect of denervation on the content of cardiac troponin-T and cardiac troponin-I in rat skeletal muscle
    Salim Fredericks
    Institute of Medicine, Universiti Brunei Darussalam, Jalan Tunku Link, Gadong, BE 1410, Brunei Darussalam
    Clin Biochem 40:423-6. 2007
    ..001). These data, combined with data on other models in the literature, indicate that re-expression of cTnT and cTnI isoforms in adult skeletal muscle is unlikely and does not interfere with cTnT assays for assessment of cardiac damage...