R D Macmillan
- Sentinel node biopsy for breast cancer may have little to offer four-node-samplers. results of a prospective comparison studyR D Macmillan
The Breast Unit, Nottingham City Hospital, Hucknall Road, NG5 1PB, Nottingham, UK
Eur J Cancer 37:1076-80. 2001..For 1 patient, the SN was positive and the 4NAS negative. SNB performed using radiolabelled colloid has no advantage over 4NAS when nodes are assessed by standard histological technique...
- Incidence of intramammary nodes in completion mastectomy specimens after axillary node sampling: implications for breast conserving surgeryR S Rampaul
Nottingham Breast Institute, Nottingham University Hospital, City Hospital Campus, Hucknall Road, Nottingham NG5 1PB, UK
Breast 17:195-8. 2008..This study aims to assess the incidence of such nodes in completion mastectomy specimens in women who have had previous breast conserving surgery and ANS...
- Prognostic value of lymphovascular invasion in women with lymph node negative invasive breast carcinomaA H S Lee
Department of Histopathology, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
Eur J Cancer 42:357-62. 2006..In conclusion, lymphovascular invasion is an independent prognostic factor in node-negative breast cancer and should be considered in decisions about adjuvant treatment in this group of women...
- Preoperative ultrasound-guided node biopsy and sentinel node augmented node sample is best practiceR D Macmillan
Nottingham Breast Institute and Department of Medical Statistics, City Hospital, Hucknall Road, Nottingham NG1 5PB, UK
Eur J Cancer 40:176-8. 2004
- Diagnosis of axillary nodal metastases by ultrasound-guided core biopsy in primary operable breast cancerA Damera
Department of Radiology, Helen Garrod Breast Screening Unit, Nottingham International Breast Education Centre, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
Br J Cancer 89:1310-3. 2003..In conclusion, US can identify abnormal nodes in patients presenting with primary operable breast cancer. In all, 65% of these nodes are malignant and this can often be confirmed with US-guided core biopsy...
- The proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancerH Zhang
Division of Pathology, School of Molecular Medical Sciences, Queen s Medical Centre, University of Nottingham, Nottingham, NG7 2UH, UK
Breast Cancer Res Treat 121:41-51. 2010..We have identified a novel subgroup of basal tumours showing FABP7 expression that have significantly better clinical outcome. Further studies analysing the role of FABP7 are therefore warranted...
- Identification of key clinical phenotypes of breast cancer using a reduced panel of protein biomarkersA R Green
Breast Cancer Pathology Research Group, Division of Oncology, School of Medicine, Academic Unit of Clinical Oncology, University of Nottingham, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
Br J Cancer 109:1886-94. 2013..As an alternative, immunohistochemical analysis applied to routinely processed tissue samples could be used to identify distinct biological classes of breast cancer...
- Survival of invasive breast cancer according to the Nottingham Prognostic Index in cases diagnosed in 1990-1999R W Blamey
The Breast Institute, Nottingham City Hospital, Nottingham NG5 1PB, UK
Eur J Cancer 43:1548-55. 2007..The Nottingham Prognostic Index (NPI) is a well established and widely used method of predicting survival of operable primary breast cancer...
- Woman feels breast lump--surgeon cannot: the role of ultrasound in arbitrationJ A Cid
The Breast Institute, City Hospital, Nottingham, UK
Eur J Cancer 40:2053-5. 2004..98). Ultrasound may be a suitable complimentary investigation, which will relieve symptoms in those with cysts and can detect small clinically--and sometimes mammographically--occult breast cancers...
- Tumour-infiltrating macrophages and clinical outcome in breast cancerS M A Mahmoud
Division of Pathology, School of Molecular Medical Sciences, University of Nottingham, Nottingham, UK
J Clin Pathol 65:159-63. 2012..In breast cancer, the presence of macrophages has been correlated with increased angiogenesis and poor prognosis but little information is available about the independent prognostic role of macrophages infiltrating breast carcinomas...
- Three-dimensional reconstruction of sentinel lymph nodes with metastatic breast cancer indicates three distinct patterns of tumour growthE C Paish
Breast Cancer Pathology Research Group, Department of Histopathology, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK
J Clin Pathol 62:617-23. 2009..Three-dimensional (3D) serial section alignment and reconstruction techniques can be used for visualisation of nodal metastasis and could provide better understanding of disease growth patterns...
- Oncological and cosmetic outcomes of oncoplastic breast conserving surgeryK S Asgeirsson
Nottingham Breast Institute, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
Eur J Surg Oncol 31:817-23. 2005..Partial breast reconstructive techniques may improve cosmesis and patient satisfaction without compromising the oncological outcomes...
- Breast imaging findings in women with BRCA1- and BRCA2-associated breast carcinomaL J Hamilton
Nottingham Breast Institute, Nottingham City Hospital, Nottingham, UK
Clin Radiol 59:895-902. 2004..To document the breast imaging findings of women with BRCA1 and BRCA2-associated breast carcinoma...
- Excision biopsy findings of patients with breast needle core biopsies reported as suspicious of malignancy (B4) or lesion of uncertain malignant potential (B3)A H S Lee
Department of Histopathology, City Hospital, Nottingham, UK
Histopathology 42:331-6. 2003..The majority of cores are reported as benign (B1), normal (B2) or malignant (B5). The predictive value of the two borderline categories suspicious of malignancy (B4) and lesion of uncertain malignant potential (B3) was studied...
- Incidence of clinically significant lymphoedema as a complication following surgery for primary operable breast cancerR S Rampaul
Breast Cancer Unit, Nottingham City Hospital, Nottingham NG1 5PB, UK
Eur J Cancer 39:2165-7. 2003..Of these 5, 3 had undergone axillary clearance, 1 ANS plus radiotherapy and only 1 had ANS alone. A policy of ANS, with prophylactic treatment for lymph node positivity either by surgery or RT alone, gives a very low rate of lymphoedema...
- Accuracy of mammography in predicting histological extent of ductal carcinoma in situ (DCIS)J Chakrabarti
Department of Breast Surgery, Nottingham Breast Institute, Nottingham City Hospital, University of Nottingham, Hucknall Road, Nottingham NG5 1PB, UK
Eur J Surg Oncol 32:1089-92. 2006..Accuracy of mammography in predicting pathological extent of ductal carcinoma in situ (DCIS)...
- Transverse Upper Gracilis (TUG) flap for volume replacement in breast conserving surgery for medial breast tumours in small to medium sized breastsS J McCulley
Department of Plastic Surgery, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, United Kingdom
J Plast Reconstr Aesthet Surg 64:1056-60. 2011..This initial experience of small volume TUG flaps used in four patients is presented to support the feasibility and assess early outcomes of this technique in the management of this niche group of patients...
- Therapeutic mammaplasty for centrally located breast tumorsS J McCulley
Department of Plastic Surgery and Breast Surgery, Nottingham City Hospital, Nottingham, United Kingdom
Plast Reconstr Surg 117:366-73. 2006..This article describes the use of therapeutic mammaplasty (a term used to describe breast reduction techniques utilized to treat breast cancer) for centrally sited breast tumors...
- Therapeutic mammaplasty--analysis of 50 consecutive casesS J McCulley
Breast Reconstruction Service, Department of Plastic Surgery, Nottingham City Hospital, UK
Br J Plast Surg 58:902-7. 2005..No patient has had a delay in adjuvant treatment. Cosmetic outcome was deemed good/excellent in 63%, satisfactory in 33%, poor in 4%. Follow-up is restricted to 3-32 months...
- Germ line mutations associated with breast cancer susceptibilityP T Iau
The Breast Unit, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
Eur J Cancer 37:300-21. 2001..Most of the available data are derived from studies on highly selected populations. The importance of other less penetrant, but more prevalent, germ line mutations may be realised in the future...
- Radioisotope for occult lesion localisation (ROLL) of the breast does not require extra radiation protection proceduresR S Rampaul
Professorial Unit of Surgery, Nottingham City Hospital, Nottingham, UK
Breast 12:150-2. 2003..Dosimetry data from patients and hospital personnel involved in the use of radioisotope for occult lesion localisation (ROLL) of the breast were collected to determine the need for extra radiation protection procedures...
- Autologous fat transfer--a review of the literature with a focus on breast cancer surgeryC W Chan
Nottingham Breast Institute, City Hospital, Hucknall Road, Nottingham, UK
J Plast Reconstr Aesthet Surg 61:1438-48. 2008..In addition, the radiological sequelae following autologous fat transfer to the breast are summarised...
- Cosmesis and satisfaction after breast-conserving surgery correlates with the percentage of breast volume excisedR A Cochrane
Nottingham City Hospital Breast Unit, Nottingham, UK
Br J Surg 90:1505-9. 2003..This study assessed cosmetic outcome relative to a combination of these factors-the estimated percentage of breast volume excised (EPBVE)...
- Prognostic significance of BRCA1 expression in sporadic breast carcinomasH Lambie
Department of Histopathology, Nottingham City Hospital, Nottingham, UK
J Pathol 200:207-13. 2003..Loss of BRCA1 expression associated with high-grade breast tumours suggests that BRCA1 may play an important role in the pathogenesis of sporadic breast cancer...
- Planning and use of therapeutic mammoplasty--Nottingham approachS J McCulley
Breast Reconstruction Service, Department of Plastic Surgery, Nottingham City Hospital, UK
Br J Plast Surg 58:889-901. 2005..Either method will move tissue that is normally excised into the cancer defect. For central tumours an inferior pedicle is usually used to both fill the defect and re-create the nipple...
- Size of invasive breast cancer and risk of local recurrence after breast-conservation therapyK S Asgeirsson
The Nottingham Breast Unit, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
Eur J Cancer 39:2462-9. 2003..A registration study of patients with cancers larger than 3 cm treated by breast conservation with or without partial breast reconstruction is proposed...
- Is the presence of mammographic comedo calcification really a prognostic factor for small screen-detected invasive breast cancers?J J James
Nottingham City Hospital, Nottingham, U K
Clin Radiol 58:54-62. 2003..We have determined prognostic factors for small screen-detected cancers in a univariate and multivariate fashion...