A J Lucking

Summary

Country: UK

Publications

  1. pmc Impaired vascular function after exposure to diesel exhaust generated at urban transient running conditions
    Stefan Barath
    Department of Public Health and Clinical Medicine, Umea University, Sweden
    Part Fibre Toxicol 7:19. 2010
  2. pmc Experimental exposure to diesel exhaust increases arterial stiffness in man
    Magnus Lundback
    Department of Respiratory Medicine and Allergy, University Hospital, Umea, Sweden
    Part Fibre Toxicol 6:7. 2009
  3. pmc Fibrin clot structure remains unaffected in young, healthy individuals after transient exposure to diesel exhaust
    Sofian Metassan
    Division of Cardiovascular and Diabetes Research, Section on Mechanisms of Thrombosis, Leeds Institute for Genetics Health and Therapeutics, Faculty of Medicine and Health, University of Leeds, Leeds, UK
    Part Fibre Toxicol 7:17. 2010
  4. ncbi request reprint Pharmacological antithrombotic adjuncts to percutaneous coronary intervention
    Andrew J Lucking
    The University of Edinburgh, Room SU 305, Chancellor s Building, 49 Little France Crescent, Edinburgh, EH16 4SU, Scotland
    Expert Opin Pharmacother 8:759-76. 2007
  5. doi request reprint Diesel exhaust inhalation increases thrombus formation in man
    Andrew J Lucking
    Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
    Eur Heart J 29:3043-51. 2008
  6. doi request reprint Effect of the small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor, PAI-749, in clinical models of fibrinolysis
    A J Lucking
    Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
    J Thromb Haemost 8:1333-9. 2010
  7. doi request reprint Characterisation and reproducibility of a human ex vivo model of thrombosis
    Andrew J Lucking
    Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
    Thromb Res 126:431-5. 2010
  8. doi request reprint P-selectin antagonism reduces thrombus formation in humans
    R Chelliah
    Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
    J Thromb Haemost 7:1915-9. 2009
  9. doi request reprint Lyophilised reconstituted human platelets increase thrombus formation in a clinical ex vivo model of deep arterial injury
    Nikhil Vilas Joshi
    Centre for Cardiovascular Sciences, University of Edinburgh, UK
    Thromb Haemost 108:176-82. 2012

Collaborators

  • David E Newby
  • Flemming R Cassee
  • R Chelliah
  • Nicholas L Mills
  • Stefan Barath
  • Magnus Lundback
  • Nikhil Vilas Joshi
  • Sofian Metassan
  • Thomas Sandstrom
  • Ken Donaldson
  • Anders Blomberg
  • Giora Z Feuerstein
  • Mike Fitzpatrick
  • Jennifer B Raftis
  • Amanda H Hunter
  • Mike Millar
  • Stefan Soderberg
  • Helen Philippou
  • Shirley Uitte de Willige
  • Jeremy P Langrish
  • Robert As Ariëns
  • Michael N Routledge
  • Christoffer Boman
  • Håkan Törnqvist
  • Ian S Mudway
  • Roger Westerholm
  • Jakob Löndahl

Detail Information

Publications9

  1. pmc Impaired vascular function after exposure to diesel exhaust generated at urban transient running conditions
    Stefan Barath
    Department of Public Health and Clinical Medicine, Umea University, Sweden
    Part Fibre Toxicol 7:19. 2010
    ..Controlled human exposure studies have demonstrated impaired vascular function after inhalation of exhaust generated by a diesel engine under idling conditions...
  2. pmc Experimental exposure to diesel exhaust increases arterial stiffness in man
    Magnus Lundback
    Department of Respiratory Medicine and Allergy, University Hospital, Umea, Sweden
    Part Fibre Toxicol 6:7. 2009
    ..abstract:..
  3. pmc Fibrin clot structure remains unaffected in young, healthy individuals after transient exposure to diesel exhaust
    Sofian Metassan
    Division of Cardiovascular and Diabetes Research, Section on Mechanisms of Thrombosis, Leeds Institute for Genetics Health and Therapeutics, Faculty of Medicine and Health, University of Leeds, Leeds, UK
    Part Fibre Toxicol 7:17. 2010
    ..These data show that there are no prothrombotic changes in fibrin clot structure in young, healthy individuals exposed to diesel exhaust...
  4. ncbi request reprint Pharmacological antithrombotic adjuncts to percutaneous coronary intervention
    Andrew J Lucking
    The University of Edinburgh, Room SU 305, Chancellor s Building, 49 Little France Crescent, Edinburgh, EH16 4SU, Scotland
    Expert Opin Pharmacother 8:759-76. 2007
    ..In this article, evidence for the role of antiplatelet and anticoagulant therapies is discussed, including the thienopyridines, glycoprotein IIb/IIIa receptor antagonists, direct thrombin inhibitors and pentasaccharides...
  5. doi request reprint Diesel exhaust inhalation increases thrombus formation in man
    Andrew J Lucking
    Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
    Eur Heart J 29:3043-51. 2008
    ..The aim of this study is to investigate the effect of diesel exhaust inhalation on platelet activation and thrombus formation in men...
  6. doi request reprint Effect of the small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor, PAI-749, in clinical models of fibrinolysis
    A J Lucking
    Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
    J Thromb Haemost 8:1333-9. 2010
    ..The principal inhibitor of fibrinolysis in vivo is plasminogen activator inhibitor-1 (PAI-1). PAI-749 is a small molecule inhibitor of PAI-1 with proven antithrombotic efficacy in several preclinical models...
  7. doi request reprint Characterisation and reproducibility of a human ex vivo model of thrombosis
    Andrew J Lucking
    Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
    Thromb Res 126:431-5. 2010
    ..The aims of this study were to characterise thrombus formation in the chamber and evaluate its reproducibility...
  8. doi request reprint P-selectin antagonism reduces thrombus formation in humans
    R Chelliah
    Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
    J Thromb Haemost 7:1915-9. 2009
    ..Platelet P-selectin expression is increased in patients with coronary heart disease, and its antagonism represents a potential future therapeutic target for the prevention and treatment of atherothrombosis...
  9. doi request reprint Lyophilised reconstituted human platelets increase thrombus formation in a clinical ex vivo model of deep arterial injury
    Nikhil Vilas Joshi
    Centre for Cardiovascular Sciences, University of Edinburgh, UK
    Thromb Haemost 108:176-82. 2012
    ..These data suggest that LHPs have the potential to serve as a therapeutic intervention during haemorrhage under circumstances of trauma, and platelet depletion or dysfunction...