Research Topics
| Richard G WhiteSummaryAffiliation: London School of Hygiene and Tropical Medicine Country: UK Publications
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Detail Information
Publications
Male circumcision for HIV prevention in sub-Saharan Africa: who, what and when?Richard G White
London School of Hygiene and Tropical Medicine, London, UK
AIDS 22:1841-50. 2008..We explore how the population-level impact of circumcision varies by target age group, coverage, time-to-scale-up, level of risk compensation and circumcision of HIV infected men...
Population-level effect of HSV-2 therapy on the incidence of HIV in sub-Saharan AfricaR G White
Infectious Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Sex Transm Infect 84:ii12-8. 2008....
Low effectiveness of syndromic treatment services for curable sexually transmitted infections in rural South AfricaR G White
Infectious Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
Sex Transm Infect 84:528-34. 2008..We estimate the effectiveness of syndromic treatment for curable STIs in rural KwaZulu-Natal, South Africa, and the trend in STI prevalences before and after the introduction of syndromic treatment in 1995...
Treating curable sexually transmitted infections to prevent HIV in Africa: still an effective control strategy?Richard G White
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
J Acquir Immune Defic Syndr 47:346-53. 2008..We explore whether treating curable STIs remains a cost-effective HIV control strategy in Africa...
Quantifying HIV-1 transmission due to contaminated injectionsRichard G White
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom
Proc Natl Acad Sci U S A 104:9794-9. 2007..This result is likely to be generalizable to many other populations in sub-Saharan Africa...
HIV epidemic trend and antiretroviral treatment need in Karonga District, MalawiR G White
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, UK
Epidemiol Infect 135:922-32. 2007..1% of adults were in need of ART in 2005. This prediction was sensitive to the assumed eligibility period, ranging from 1.6% to 2.6% if the eligibility period was instead assumed to be 1.5 or 2.5 years, respectively...
Commentary: What can we make of an association between human immunodeficiency virus prevalence and population mobility?Richard G White
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, 49 Bedford Square, London WC1B 3DP, UK
Int J Epidemiol 32:753-4. 2003
Can population differences explain the contrasting results of the Mwanza, Rakai, and Masaka HIV/sexually transmitted disease intervention trials?: A modeling studyRichard G White
London School of Hygiene and Tropical Medicine, London, UK
J Acquir Immune Defic Syndr 37:1500-13. 2004....
Understanding the differences between contrasting HIV epidemics in east and west Africa: results from a simulation model of the Four Cities StudyKate K Orroth
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Sex Transm Infect 83:i5-16. 2007....
Empirical observations underestimate the proportion of human immunodeficiency virus infections attributable to sexually transmitted diseases in the Mwanza and Rakai sexually transmitted disease treatment trials: Simulation resultsKate K Orroth
London School of Hygiene and Tropical Medicine, London, UK
Sex Transm Dis 33:536-44. 2006..Empirical PAF estimates from the Mwanza and Rakai trials indicated the proportion of HIV infections attributable to STDs was higher in Mwanza than Rakai...
Higher risk behaviour and rates of sexually transmitted diseases in Mwanza compared to Uganda may help explain HIV prevention trial outcomesKate K Orroth
London School of Hygiene and Tropical Medicine, London, UK
AIDS 17:2653-60. 2003....
Population-level effect of potential HSV2 prophylactic vaccines on HIV incidence in sub-Saharan AfricaEsther E Freeman
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
Vaccine 27:940-6. 2009..Over 20 years, in most scenarios fewer than 100 vaccinations were required to avert one HIV infection. HSV2 vaccines could have a substantial impact on HIV incidence. Intensified efforts are needed to develop an effective HSV2 vaccine...
Exploring the potential impact of a reduction in partnership concurrency on HIV incidence in rural Uganda: a modeling studyNicky McCreesh
Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, United Kingdom
Sex Transm Dis 39:407-13. 2012..This modeling study explores the potential impact of an intervention to reduce partnership concurrency on HIV incidence in contemporary rural Uganda, keeping incidence of sex acts and partnerships in the population constant...
Attempting to explain heterogeneous HIV epidemics in sub-Saharan Africa: potential role of historical changes in risk behaviour and male circumcisionKate K Orroth
Epidemiology and Public Heath, London School of Hygiene and Tropical Medicine, London, UK
Sex Transm Infect 87:640-5. 2011..They also investigate the effects of different prevalence of male circumcision on the HIV epidemics in the four cities...
HIV and STI prevalence and determinants among male migrant workers in IndiaSangeeta S Dave
Institute for Women s Health, University College London, London, United Kingdom
PLoS ONE 7:e43576. 2012..Our objective was to estimate for the first time the prevalence and determinants of human immunodeficiency virus type 1 (HIV-1) and sexually transmitted infections (STIs) among male migrants in India...
Evaluation of respondent-driven samplingNicky McCreesh
Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, UK
Epidemiology 23:138-47. 2012..We evaluated respondent-driven sampling by comparing estimates from a respondent-driven sampling survey with total population data...
Attaining realistic and substantial reductions in HIV incidence: model projections of combining microbicide and male circumcision interventions in rural UgandaAndrew P Cox
Social and Mathematical Epidemiology Group, Centre for Mathematical Modelling of Infectious Disease, London School of Hygiene and Tropical Medicine, London, UK
Sex Transm Infect 87:635-9. 2011..This study simulates the potential impact of male circumcision and female microbicide interventions, singularly and in combination, in rural Uganda...
Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studiesMarie Claude Boily
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
Lancet Infect Dis 9:118-29. 2009..Efforts are needed to better understand these differences and to quantify infectivity in low-income countries...
Polygyny and symmetric concurrency: comparing long-duration sexually transmitted infection prevalence using simulated sexual networksShalini Santhakumaran
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Sex Transm Infect 86:553-8. 2010....
HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV preventionRebecca F Baggaley
Department of Infectious Disease Epidemiology, MRC Centre for Outbreak Analysis and Modelling, Faculty of Medicine, Imperial College London, Paddington, London, UK
Int J Epidemiol 39:1048-63. 2010..We assessed the per-act and per-partner HIV transmission risk from AI exposure for heterosexuals and MSM and its implications for HIV prevention...
Systematic review of orogenital HIV-1 transmission probabilitiesRebecca F Baggaley
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, UK
Int J Epidemiol 37:1255-65. 2008..The objective was to assess the risk of HIV transmission from orogenital intercourse (OI)...
Periodic active case finding for TB: when to look?Peter J Dodd
London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 6:e29130. 2011..To investigate the factors influencing the performance and cost-efficacy of periodic rounds of active case finding (ACF) for TB...
The role of the natural epidemic dynamics and migration in explaining the course of the HIV epidemic in rural Uganda: a modelling studyLeigh A Shafer
Medical Research Council Unit on AIDS Uganda Virus Research Institute, Entebbe, Uganda and London School of Hygiene and Tropical Medicine, London, UK
Int J Epidemiol 40:397-404. 2011..We simultaneously fit a mathematical model to the contrasting prevalence trends by age/gender in a southwest Ugandan cohort, which has never been done before...
Antiretroviral treatment cohort analysis using time-updated CD4 counts: assessment of bias with different analytic methodsKatharina Kranzer
Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 6:e27763. 2011..The time-point when the CD4+ count is assumed to change potentially biases effect estimates but methods used to estimate this are infrequently reported...
Calibrating models in economic evaluation: a seven-step approachTazio Vanni
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK
Pharmacoeconomics 29:35-49. 2011..In order to avoid the scepticism regarding calibration, we ought to unify the way we approach the problems and report the methods used, and continue to investigate different methods...
Do behavioural differences help to explain variations in HIV prevalence in adolescents in sub-Saharan Africa?R Chapman
London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
Trop Med Int Health 15:554-66. 2010....
Comparison of STD prevalences in the Mwanza, Rakai, and Masaka trial populations: the role of selection bias and diagnostic errorsK K Orroth
London School of Hygiene and Tropical Medicine, London, UK
Sex Transm Infect 79:98-105. 2003..To evaluate the effects of such biases on STD prevalence estimates from three community randomised trials of STD treatment for HIV prevention in Masaka and Rakai, Uganda and Mwanza, Tanzania...
Behaviour change and competitive exclusion can explain the diverging HIV-1 and HIV-2 prevalence trends in Guinea-BissauW P Schmidt
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
Epidemiol Infect 136:551-61. 2008..Importantly for public health, HIV-1 prevalence was predicted to continue increasing and to become the dominant HIV type by 2010. Data collection is required to validate this prediction...
Evaluation of the role of location and distance in recruitment in respondent-driven samplingNicky McCreesh
Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, UK
Int J Health Geogr 10:56. 2011..The role of the spatial distribution of the target population has not been robustly examined for RDS. We examine patterns of recruitment by location, and how they may have biased an RDS study findings...
Heterosexual HIV-1 infectiousness and antiretroviral use: systematic review of prospective studies of discordant couplesRebecca F Baggaley
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, United Kingdom
Epidemiology 24:110-21. 2013....
Understanding the impact of male circumcision interventions on the spread of HIV in southern AfricaTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
PLoS ONE 3:e2212. 2008..We have used a mathematical model, parameterised using existing trial findings, to understand and predict the impact of circumcision programmes at the population level...
Strong association between in-migration and HIV prevalence in urban sub-Saharan AfricaHelene A C M Voeten
Department of Public Health, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Sex Transm Dis 37:240-3. 2010..In this ecological analysis, we explore how much variation in HIV prevalence in urban sub-Saharan Africa is explained by in-migration...
Proportion of new HIV infections attributable to herpes simplex 2 increases over time: simulations of the changing role of sexually transmitted infections in sub-Saharan African HIV epidemicsEsther E Freeman
Harvard Medical School, Francis Weld Peabody Society, 260 Longwood Ave, Boston, MA 02115, USA
Sex Transm Infect 83:i17-24. 2007..To understand the changing impact of herpes simplex 2 (HSV-2) and other sexually transmitted infections (STIs) on HIV incidence over time in four sub-Saharan African cities, using simulation models...
Risk of HIV-1 transmission for parenteral exposure and blood transfusion: a systematic review and meta-analysisRebecca F Baggaley
AIDS 20:805-12. 2006..Further work is needed to better estimate transmission probability related to contaminated injections and its likely contribution to overall HIV transmission...
How important are unsafe medical injections in the spread of HIV in Africa?Richard J Hayes
Sex Transm Dis 33:135-6. 2006
HIV incidence and recent injections among adults in rural southwestern UgandaJimmy A Whitworth
Medical Research Council Programme on AIDS, Uganda Virus Research Institute, Entebbe, Uganda
AIDS 21:1056-8. 2007..This association could either be the result of injections causing HIV infection or, more likely, injections for seroconversion illnesses or other consequences of unsafe sex...
Amplified HIV transmission during early-stage infectionRichard J Hayes
J Infect Dis 193:604-5; author reply 605-6. 2006
