Research Topics
| Deborah Watson-JonesSummaryAffiliation: London School of Hygiene and Tropical Medicine Country: UK Publications
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Detail Information
Publications
Reasons for receiving or not receiving HPV vaccination in primary schoolgirls in Tanzania: a case control studyDeborah Watson-Jones
London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 7:e45231. 2012..We examined the characteristics of receivers and non-receivers of HPV vaccination in Tanzania and identified reasons for not receiving the vaccine...
Human papillomavirus vaccination in Tanzanian schoolgirls: cluster-randomized trial comparing 2 vaccine-delivery strategiesDeborah Watson-Jones
London School of Hygiene and Tropical Medicine, London, UK
J Infect Dis 206:678-86. 2012..We compared vaccine coverage achieved by 2 different delivery strategies for the quadrivalent human papillomavirus (HPV) vaccine in Tanzanian schoolgirls...
Pregnancy and contraceptive use among women participating in an HIV prevention trial in TanzaniaAderonke Odutola
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
Sex Transm Infect 88:436-43. 2012....
Missed opportunities: poor linkage into ongoing care for HIV-positive pregnant women in Mwanza, TanzaniaDeborah Watson-Jones
Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 7:e40091. 2012..We measured the proportion of HIV-positive pregnant women in Mwanza city, Tanzania, who completed the cascade of care from antenatal HIV diagnosis to assessment and engagement in care in adult HIV clinics...
Syphilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancyDeborah Watson-Jones
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
J Infect Dis 186:940-7. 2002..Syphilis continues to be a major cause of pregnancy loss and adverse pregnancy outcome among women who do not receive antenatal syphilis screening and treatment...
Risk factors for HIV incidence in women participating in an HSV suppressive treatment trial in TanzaniaDeborah Watson-Jones
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
AIDS 23:415-22. 2009..Risk factors for HIV incidence were examined in the context of 3-monthly follow-up visits offering both voluntary counselling and testing and care for sexually transmitted infections...
Effect of herpes simplex suppression on incidence of HIV among women in TanzaniaDeborah Watson-Jones
London School of Hygiene and Tropical Medicine, London
N Engl J Med 358:1560-71. 2008..This study tested the hypothesis that HSV-2 suppressive therapy reduces the risk of HIV acquisition...
Risk factors for herpes simplex virus type 2 and HIV among women at high risk in northwestern Tanzania: preparing for an HSV-2 intervention trialDeborah Watson-Jones
London School of Hygiene and Tropical Medicine, London, England
J Acquir Immune Defic Syndr 46:631-42. 2007..To determine prevalence of and risk factors for herpes simplex virus type 2 (HSV-2) and HIV among women being screened for a randomized, controlled trial of HSV suppressive therapy in northwestern Tanzania...
Measurement and predictors of adherence in a trial of HSV suppressive therapy in TanzaniaDeborah Watson-Jones
London School of Hygiene and Tropical Medicine, London, UK
Contemp Clin Trials 30:504-12. 2009..Use of biomarkers may alert investigators to adherence problems...
Antenatal syphilis screening in sub-Saharan Africa: lessons learned from TanzaniaDeborah Watson-Jones
London School of Hygiene and Tropical Medicine, London, UK
Trop Med Int Health 10:934-43. 2005....
Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomesDeborah Watson-Jones
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
J Infect Dis 186:948-57. 2002..4-1.4) or low-titer active syphilis (OR, 0.95; 95% CI, 0.6-1.5), compared with seronegative women. Single-dose treatment is effective in preventing adverse pregnancy outcomes attributable to maternal syphilis...
Long-term impact of acyclovir suppressive therapy on genital and plasma HIV RNA in Tanzanian women: a randomized controlled trialClare Tanton
London School of Hygiene and Tropical Medicine, London, United Kingdom
J Infect Dis 201:1285-97. 2010..Herpes simplex virus (HSV) suppressive therapy reduces genital and plasma human immunodeficiency virus type 1 (HIV-1) RNA over periods up to 3 months, but the long-term effect is unknown...
Long-term biological and behavioural impact of an adolescent sexual health intervention in Tanzania: follow-up survey of the community-based MEMA kwa Vijana TrialAoife M Doyle
London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS Med 7:e1000287. 2010..A further impact evaluation survey in 2007/8 ( approximately 9 years post-intervention) tested this hypothesis...
Are women who work in bars, guesthouses and similar facilities a suitable study population for vaginal microbicide trials in Africa?Andrew Vallely
London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 5:e10661. 2010..A feasibility study was conducted to investigate whether an occupational at-risk cohort of women in Mwanza, Tanzania are a suitable study population for future phase III vaginal microbicide trials...
Suitability of simple human immunodeficiency virus rapid tests in clinical trials in community-based clinic settingsDean B Everett
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom
J Clin Microbiol 47:1058-62. 2009..9 to 100%), and 100% for the parallel SR (95% CI, 99.4 to 100%). SR tests are suitable for use in community-based clinical research settings to assess eligibility both for trial participation and for the provision of on-site VCT services...
Microbicides development program, Tanzania-baseline characteristics of an occupational cohort and reattendance at 3 monthsAndrew Vallely
London School of Hygiene and Tropical Medicine, Keppel St, London, United Kingdom
Sex Transm Dis 34:638-43. 2007..To determine baseline characteristics of an occupational cohort of women in Mwanza City, Tanzania, and factors associated with reattendance at 3 months, in preparation for a microbicide trial...
A qualitative study of participant adherence in a randomized controlled trial of herpes suppressive therapy for HIV prevention in TanzaniaMary L Plummer
London School of Hygiene and Tropical Medicine, London, UK
AIDS Care 22:499-508. 2010..Methodological research is also needed to improve adherence measures...
Use of acyclovir for suppression of human immunodeficiency virus infection is not associated with genotypic evidence of herpes simplex virus type 2 resistance to acyclovir: analysis of specimens from three phase III trialsDeborah Watson-Jones
London School of Hygiene and Tropical Medicine, London, United Kingdom
J Clin Microbiol 48:3496-503. 2010..Overall, UL23 is highly polymorphic compared to other loci in HSV-2, but no drug resistance mutations were detected that could explain the failure to reduce HIV incidence or to prevent HIV-1 transmission in these studies...
Adverse birth outcomes in United Republic of Tanzania--impact and prevention of maternal risk factorsDeborah Watson Jones
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, England
Bull World Health Organ 85:9-18. 2007..To determine risk factors for poor birth outcome and their population attributable fractions...
Patient attrition between diagnosis with HIV in pregnancy-related services and long-term HIV care and treatment services in Kenya: a retrospective studyLaura Ferguson
Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom
J Acquir Immune Defic Syndr 60:e90-7. 2012..There has been little attention, until recently, to linking women who test HIV positive in pregnancy-related services to long-term HIV care and treatment services...
The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposureAoife M Doyle
London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 6:e24866. 2011..The aim of this paper was to assess the differential impact of the intervention according to gender, age, marital status, number of years of exposure and time since last exposure to the intervention...
Low specificity of the Murex fourth-generation HIV enzyme immunoassay in Tanzanian adolescentsDean B Everett
London School of Hygiene and Tropical Medicine, London, UK
Trop Med Int Health 12:1323-6. 2007..To determine the specificity of the Abbott Murex HIV antigen/antibody combination enzyme immunoassay (EIA) for the diagnosis of HIV infection in Tanzania...
Correlates of HIV-1 genital shedding in Tanzanian womenClare Tanton
Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 6:e17480. 2011..i.d vs. placebo) in Tanzania...
Uptake of voluntary counselling and testing among young people participating in an HIV prevention trial: comparison of opt-out and opt-in strategiesKathy Baisley
London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 7:e42108. 2012..We compare VCT uptake using two delivery strategies (opt-in and opt-out) within the MEMA kwa Vijana trial in 20 communities in northwest Tanzania...
Linking women who test HIV-positive in pregnancy-related services to long-term HIV care and treatment services: a systematic reviewLaura Ferguson
Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
Trop Med Int Health 17:564-80. 2012....
Association of schistosomiasis with false-positive HIV test results in an African adolescent populationDean B Everett
London School of Hygiene and Tropical Medicine, London, UK
J Clin Microbiol 48:1570-7. 2010..In Africa, endemic infections may affect the specificities of immunoassays for HIV infection. Caution should be used when the results of 4th-generation HIV test results are interpreted for African adolescent populations...
Human papillomavirus infection and increased risk of HIV acquisition. A systematic review and meta-analysisCatherine F Houlihan
Clinical Research Department, London School of Hygiene and Tropical Medicine, London, UK
AIDS 26:2211-22. 2012..We systematically reviewed the evidence for an association of HPV infection with HIV acquisition in women, heterosexual men and men who have sex with men (MSM)...
Neonatal mortality risk associated with preterm birth in East Africa, adjusted by weight for gestational age: individual participant level meta-analysisTanya Marchant
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS Med 9:e1001292. 2012..Our objective was to estimate the neonatal mortality risk associated with preterm birth when stratified by weight for gestational age in the high mortality setting of East Africa...
Treatment of sexually transmitted infections for HIV prevention: end of the road or new beginning?Richard Hayes
London School of Hygiene and Tropical Medicine, London, UK
AIDS 24:S15-26. 2010..It should be promoted as an essential component of HIV control programs in communities in which the burden of STIs is substantial...
Vaginal Practices among Women at High Risk of HIV Infection in Uganda and Tanzania: Recorded Behaviour from a Daily Pictorial DiarySuzanna C Francis
Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom Mwanza Intervention Trials Unit, National Institute for Medical Research Mwanza Centre, Mwanza, Tanzania
PLoS ONE 8:e59085. 2013..Vaginal practices among women at high risk in Uganda and Tanzania: recorded behaviour from a daily pictorial diary...
Provider-initiated testing and counselling programmes in sub-Saharan Africa: a systematic review of their operational implementationMaria Roura
London School of Hygiene and Tropical Medicine, London, UK
AIDS 27:617-26. 2013..This review examined the operational implementation of provider-initiated testing and counselling (PITC) programmes in sub-Saharan Africa...
Prevention of mother-to-child transmission of HIV: assessing the accuracy of routinely collected data on maternal antiretroviral prophylaxis coverage in KenyaLaura Ferguson
Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Sex Transm Infect 88:120-4. 2012..To explore the accuracy of routinely collected prevention of mother-to-child transmission of HIV (PMTCT) coverage data in Kenya...
Avoiding HIV and dying of syphilisRosanna W Peeling
Diagnostics Research and Development, UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, WHO, CH-1211 Geneva 27, Switzerland
Lancet 364:1561-3. 2004
A typology of groups at risk of HIV/STI in a gold mining town in north-western TanzaniaNicola Desmond
National Institute for Medical Research, NIMR AMREF LSHTM Collaborative Projects, PO Box 11936, Mwanza, Tanzania
Soc Sci Med 60:1739-49. 2005..The methodology also enabled an approach to interventions sensitive to different circumstances associated with risk within the town while identifying structural factors affecting risk at the level of the town as a whole...
Extensive antiretroviral therapy resistance in an HIV-infected Zimbabwean patient in the UKElizabeth Foley
AIDS 17:2404-5. 2003
