Deborah Watson-Jones

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. pmc A qualitative study of HPV vaccine acceptability among health workers, teachers, parents, female pupils, and religious leaders in northwest Tanzania
    Pieter Remes
    Mwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza, Tanzania
    Vaccine 30:5363-7. 2012
  2. pmc Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania
    Wilm Quentin
    Department of Health Care Management, Berlin University of Technology, Strasse des 17 Juni 135, Berlin, 10623, Germany
    BMC Med 10:137. 2012
  3. pmc High prevalence and incidence of human papillomavirus in a cohort of healthy young African female subjects
    Deborah Watson-Jones
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Sex Transm Infect 89:358-65. 2013
  4. pmc Reasons for receiving or not receiving HPV vaccination in primary schoolgirls in Tanzania: a case control study
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 7:e45231. 2012
  5. pmc Human papillomavirus vaccination in Tanzanian schoolgirls: cluster-randomized trial comparing 2 vaccine-delivery strategies
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, UK
    J Infect Dis 206:678-86. 2012
  6. pmc Pregnancy and contraceptive use among women participating in an HIV prevention trial in Tanzania
    Aderonke Odutola
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Sex Transm Infect 88:436-43. 2012
  7. pmc Missed opportunities: poor linkage into ongoing care for HIV-positive pregnant women in Mwanza, Tanzania
    Deborah Watson-Jones
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 7:e40091. 2012
  8. ncbi request reprint Antenatal syphilis screening in sub-Saharan Africa: lessons learned from Tanzania
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 10:934-43. 2005
  9. ncbi request reprint Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomes
    Deborah Watson-Jones
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 186:948-57. 2002
  10. pmc Risk factors for herpes simplex virus type 2 and HIV among women at high risk in northwestern Tanzania: preparing for an HSV-2 intervention trial
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, England
    J Acquir Immune Defic Syndr 46:631-42. 2007

Detail Information

Publications43

  1. pmc A qualitative study of HPV vaccine acceptability among health workers, teachers, parents, female pupils, and religious leaders in northwest Tanzania
    Pieter Remes
    Mwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza, Tanzania
    Vaccine 30:5363-7. 2012
    ..As human papillomavirus (HPV) vaccines become available in developing countries, acceptability studies can help to better understand potential barriers and facilitators of HPV vaccination and guide immunisation programs...
  2. pmc Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania
    Wilm Quentin
    Department of Health Care Management, Berlin University of Technology, Strasse des 17 Juni 135, Berlin, 10623, Germany
    BMC Med 10:137. 2012
    ..This study aimed to estimate the costs of a school-based HPV vaccination project in three districts in Mwanza Region (NCT ID: NCT01173900), Tanzania and to model incremental scaled-up costs of a regional vaccination program...
  3. pmc High prevalence and incidence of human papillomavirus in a cohort of healthy young African female subjects
    Deborah Watson-Jones
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Sex Transm Infect 89:358-65. 2013
    ..We measured the prevalence and incidence of human papillomavirus (HPV) infection in young female subjects recruited for a safety and immunogenicity trial of the bivalent HPV-16/18 vaccine in Tanzania...
  4. pmc Reasons for receiving or not receiving HPV vaccination in primary schoolgirls in Tanzania: a case control study
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 7:e45231. 2012
    ..We examined the characteristics of receivers and non-receivers of HPV vaccination in Tanzania and identified reasons for not receiving the vaccine...
  5. pmc Human papillomavirus vaccination in Tanzanian schoolgirls: cluster-randomized trial comparing 2 vaccine-delivery strategies
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, UK
    J Infect Dis 206:678-86. 2012
    ..We compared vaccine coverage achieved by 2 different delivery strategies for the quadrivalent human papillomavirus (HPV) vaccine in Tanzanian schoolgirls...
  6. pmc Pregnancy and contraceptive use among women participating in an HIV prevention trial in Tanzania
    Aderonke Odutola
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Sex Transm Infect 88:436-43. 2012
    ....
  7. pmc Missed opportunities: poor linkage into ongoing care for HIV-positive pregnant women in Mwanza, Tanzania
    Deborah Watson-Jones
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 7:e40091. 2012
    ..We measured the proportion of HIV-positive pregnant women in Mwanza city, Tanzania, who completed the cascade of care from antenatal HIV diagnosis to assessment and engagement in care in adult HIV clinics...
  8. ncbi request reprint Antenatal syphilis screening in sub-Saharan Africa: lessons learned from Tanzania
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 10:934-43. 2005
    ....
  9. ncbi request reprint Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomes
    Deborah Watson-Jones
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 186:948-57. 2002
    ..4-1.4) or low-titer active syphilis (OR, 0.95; 95% CI, 0.6-1.5), compared with seronegative women. Single-dose treatment is effective in preventing adverse pregnancy outcomes attributable to maternal syphilis...
  10. pmc Risk factors for herpes simplex virus type 2 and HIV among women at high risk in northwestern Tanzania: preparing for an HSV-2 intervention trial
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, England
    J Acquir Immune Defic Syndr 46:631-42. 2007
    ..To determine prevalence of and risk factors for herpes simplex virus type 2 (HSV-2) and HIV among women being screened for a randomized, controlled trial of HSV suppressive therapy in northwestern Tanzania...
  11. pmc Effect of herpes simplex suppression on incidence of HIV among women in Tanzania
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London
    N Engl J Med 358:1560-71. 2008
    ..This study tested the hypothesis that HSV-2 suppressive therapy reduces the risk of HIV acquisition...
  12. pmc Risk factors for HIV incidence in women participating in an HSV suppressive treatment trial in Tanzania
    Deborah Watson-Jones
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    AIDS 23:415-22. 2009
    ..Risk factors for HIV incidence were examined in the context of 3-monthly follow-up visits offering both voluntary counselling and testing and care for sexually transmitted infections...
  13. doi request reprint Measurement and predictors of adherence in a trial of HSV suppressive therapy in Tanzania
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, UK
    Contemp Clin Trials 30:504-12. 2009
    ..Use of biomarkers may alert investigators to adherence problems...
  14. ncbi request reprint Syphilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancy
    Deborah Watson-Jones
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 186:940-7. 2002
    ..Syphilis continues to be a major cause of pregnancy loss and adverse pregnancy outcome among women who do not receive antenatal syphilis screening and treatment...
  15. pmc Long-term impact of acyclovir suppressive therapy on genital and plasma HIV RNA in Tanzanian women: a randomized controlled trial
    Clare Tanton
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 201:1285-97. 2010
    ..Herpes simplex virus (HSV) suppressive therapy reduces genital and plasma human immunodeficiency virus type 1 (HIV-1) RNA over periods up to 3 months, but the long-term effect is unknown...
  16. ncbi request reprint Microbicides development program, Tanzania-baseline characteristics of an occupational cohort and reattendance at 3 months
    Andrew Vallely
    London School of Hygiene and Tropical Medicine, Keppel St, London, United Kingdom
    Sex Transm Dis 34:638-43. 2007
    ..To determine baseline characteristics of an occupational cohort of women in Mwanza City, Tanzania, and factors associated with reattendance at 3 months, in preparation for a microbicide trial...
  17. pmc Long-term biological and behavioural impact of an adolescent sexual health intervention in Tanzania: follow-up survey of the community-based MEMA kwa Vijana Trial
    Aoife M Doyle
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Med 7:e1000287. 2010
    ..A further impact evaluation survey in 2007/8 ( approximately 9 years post-intervention) tested this hypothesis...
  18. pmc Adverse birth outcomes in United Republic of Tanzania--impact and prevention of maternal risk factors
    Deborah Watson-Jones
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, England
    Bull World Health Organ 85:9-18. 2007
    ..To determine risk factors for poor birth outcome and their population attributable fractions...
  19. pmc Are women who work in bars, guesthouses and similar facilities a suitable study population for vaginal microbicide trials in Africa?
    Andrew Vallely
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 5:e10661. 2010
    ..A feasibility study was conducted to investigate whether an occupational at-risk cohort of women in Mwanza, Tanzania are a suitable study population for future phase III vaginal microbicide trials...
  20. ncbi request reprint Low specificity of the Murex fourth-generation HIV enzyme immunoassay in Tanzanian adolescents
    Dean B Everett
    London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 12:1323-6. 2007
    ..To determine the specificity of the Abbott Murex HIV antigen/antibody combination enzyme immunoassay (EIA) for the diagnosis of HIV infection in Tanzania...
  21. doi request reprint A qualitative study of participant adherence in a randomized controlled trial of herpes suppressive therapy for HIV prevention in Tanzania
    Mary L Plummer
    London School of Hygiene and Tropical Medicine, London, UK
    AIDS Care 22:499-508. 2010
    ..Methodological research is also needed to improve adherence measures...
  22. pmc Use of acyclovir for suppression of human immunodeficiency virus infection is not associated with genotypic evidence of herpes simplex virus type 2 resistance to acyclovir: analysis of specimens from three phase III trials
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Clin Microbiol 48:3496-503. 2010
    ..Overall, UL23 is highly polymorphic compared to other loci in HSV-2, but no drug resistance mutations were detected that could explain the failure to reduce HIV incidence or to prevent HIV-1 transmission in these studies...
  23. pmc The epidemiology of HIV and HSV-2 infections among women participating in microbicide and vaccine feasibility studies in Northern Tanzania
    Saidi H Kapiga
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 8:e68825. 2013
    ..We examined the prevalence and incidence of HIV and HSV-2, and associated risk factors...
  24. doi request reprint Impact of malaria and helminth infections on immunogenicity of the human papillomavirus-16/18 AS04-adjuvanted vaccine in Tanzania
    Joelle Brown
    University of California, San Francisco, Department of Epidemiology and Biostatistics, San Francisco, CA, USA University of California, Los Angeles, Department of Epidemiology, Los Angeles, CA, USA Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK Mwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza, Tanzania
    Vaccine 32:611-7. 2014
    ..We conducted a cohort study to measure the influence of malaria and helminth infections on the immunogenicity of the bivalent HPV-16/18 vaccine...
  25. pmc Suitability of simple human immunodeficiency virus rapid tests in clinical trials in community-based clinic settings
    Dean B Everett
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom
    J Clin Microbiol 47:1058-62. 2009
    ..9 to 100%), and 100% for the parallel SR (95% CI, 99.4 to 100%). SR tests are suitable for use in community-based clinical research settings to assess eligibility both for trial participation and for the provision of on-site VCT services...
  26. doi request reprint Patient attrition between diagnosis with HIV in pregnancy-related services and long-term HIV care and treatment services in Kenya: a retrospective study
    Laura Ferguson
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Acquir Immune Defic Syndr 60:e90-7. 2012
    ..There has been little attention, until recently, to linking women who test HIV positive in pregnancy-related services to long-term HIV care and treatment services...
  27. pmc The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure
    Aoife M Doyle
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 6:e24866. 2011
    ..The aim of this paper was to assess the differential impact of the intervention according to gender, age, marital status, number of years of exposure and time since last exposure to the intervention...
  28. pmc Correlates of HIV-1 genital shedding in Tanzanian women
    Clare Tanton
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 6:e17480. 2011
    ..i.d vs. placebo) in Tanzania...
  29. doi request reprint Provider-initiated testing and counselling programmes in sub-Saharan Africa: a systematic review of their operational implementation
    Maria Roura
    London School of Hygiene and Tropical Medicine, London, UK
    AIDS 27:617-26. 2013
    ..This review examined the operational implementation of provider-initiated testing and counselling (PITC) programmes in sub-Saharan Africa...
  30. pmc Uptake of voluntary counselling and testing among young people participating in an HIV prevention trial: comparison of opt-out and opt-in strategies
    Kathy Baisley
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 7:e42108. 2012
    ..We compare VCT uptake using two delivery strategies (opt-in and opt-out) within the MEMA kwa Vijana trial in 20 communities in northwest Tanzania...
  31. doi request reprint Linking women who test HIV-positive in pregnancy-related services to long-term HIV care and treatment services: a systematic review
    Laura Ferguson
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 17:564-80. 2012
    ....
  32. pmc Vaginal practices among women at high risk of HIV infection in Uganda and Tanzania: recorded behaviour from a daily pictorial diary
    Suzanna C Francis
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 8:e59085. 2013
    ..The aim of the study was to describe and compare IVP using a daily pictorial diary...
  33. pmc Association of schistosomiasis with false-positive HIV test results in an African adolescent population
    Dean B Everett
    London School of Hygiene and Tropical Medicine, London, UK
    J Clin Microbiol 48:1570-7. 2010
    ..In Africa, endemic infections may affect the specificities of immunoassays for HIV infection. Caution should be used when the results of 4th-generation HIV test results are interpreted for African adolescent populations...
  34. doi request reprint Linking Women Who Test HIV-Positive in Pregnancy-Related Services to HIV Care and Treatment Services in Kenya: A Mixed Methods Prospective Cohort Study
    Laura Ferguson
    Institute for Global Health, University of Southern California, Los Angeles, California, United States of America MRC Tropical Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom University of Nairobi Institute for Tropical and Infectious Diseases, Nairobi, Kenya
    PLoS ONE 9:e89764. 2014
    ..There has been insufficient attention to long-term care and treatment for pregnant women diagnosed with HIV...
  35. pmc Risk factors for unplanned pregnancy among young women in Tanzania
    Clara Calvert
    Research Degree Student, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
    J Fam Plann Reprod Health Care 39:e2. 2013
    ..In order to effectively target future interventions, this study aimed to identify risk factors for unplanned pregnancy among young women in Mwanza, Tanzania...
  36. pmc Human papillomavirus infection and increased risk of HIV acquisition. A systematic review and meta-analysis
    Catherine F Houlihan
    Clinical Research Department, London School of Hygiene and Tropical Medicine, London, UK
    AIDS 26:2211-22. 2012
    ..We systematically reviewed the evidence for an association of HPV infection with HIV acquisition in women, heterosexual men and men who have sex with men (MSM)...
  37. pmc Neonatal mortality risk associated with preterm birth in East Africa, adjusted by weight for gestational age: individual participant level meta-analysis
    Tanya Marchant
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Med 9:e1001292. 2012
    ..Our objective was to estimate the neonatal mortality risk associated with preterm birth when stratified by weight for gestational age in the high mortality setting of East Africa...
  38. pmc Treatment of sexually transmitted infections for HIV prevention: end of the road or new beginning?
    Richard Hayes
    London School of Hygiene and Tropical Medicine, London, UK
    AIDS 24:S15-26. 2010
    ..It should be promoted as an essential component of HIV control programs in communities in which the burden of STIs is substantial...
  39. doi request reprint Prevention of mother-to-child transmission of HIV: assessing the accuracy of routinely collected data on maternal antiretroviral prophylaxis coverage in Kenya
    Laura Ferguson
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Sex Transm Infect 88:120-4. 2012
    ..To explore the accuracy of routinely collected prevention of mother-to-child transmission of HIV (PMTCT) coverage data in Kenya...
  40. doi request reprint HPTN 071 (PopART): Rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment - a study protocol for a cluster randomised trial
    Richard Hayes
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trials 15:57. 2014
    ..We describe the rationale and design of a trial to evaluate this hypothesis...
  41. ncbi request reprint Avoiding HIV and dying of syphilis
    Rosanna W Peeling
    Diagnostics Research and Development, UNICEF UNDP World Bank WHO Special Programme for Research and Training in Tropical Diseases, WHO, CH 1211 Geneva 27, Switzerland
    Lancet 364:1561-3. 2004
  42. ncbi request reprint A typology of groups at risk of HIV/STI in a gold mining town in north-western Tanzania
    Nicola Desmond
    National Institute for Medical Research, NIMR AMREF LSHTM Collaborative Projects, PO Box 11936, Mwanza, Tanzania
    Soc Sci Med 60:1739-49. 2005
    ..The methodology also enabled an approach to interventions sensitive to different circumstances associated with risk within the town while identifying structural factors affecting risk at the level of the town as a whole...
  43. ncbi request reprint Extensive antiretroviral therapy resistance in an HIV-infected Zimbabwean patient in the UK
    Elizabeth Foley
    AIDS 17:2404-5. 2003