Anthony W Solomon

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. ncbi request reprint Operational evaluation of the use of photographs for grading active trachoma
    Anthony W Solomon
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 74:505-8. 2006
  2. ncbi request reprint Lymphoma masquerading as a peritoneal dialysis catheter leak
    A W Solomon
    Department of Renal Medicine and Transplantation, Royal London Hospital, Whitechapel, London, UK
    Kidney Int 72:904. 2007
  3. ncbi request reprint Mass treatment with single-dose azithromycin for trachoma
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
    N Engl J Med 351:1962-71. 2004
  4. pmc Diagnosis and assessment of trachoma
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom
    Clin Microbiol Rev 17:982-1011, table of contents. 2004
  5. pmc Impact of mass distribution of azithromycin on the antibiotic susceptibilities of ocular Chlamydia trachomatis
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom
    Antimicrob Agents Chemother 49:4804-6. 2005
  6. pmc Urine output on an intensive care unit: case-control study
    Anthony W Solomon
    General Intensive Care Unit, St George s Hospital, London, UK
    BMJ 341:c6761. 2010
  7. pmc Estimating household and community transmission of ocular Chlamydia trachomatis
    Isobel M Blake
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    PLoS Negl Trop Dis 3:e401. 2009
  8. pmc Targeting antibiotics to households for trachoma control
    Isobel M Blake
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Negl Trop Dis 4:e862. 2010
  9. pmc The development of an age-structured model for trachoma transmission dynamics, pathogenesis and control
    Manoj Gambhir
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Negl Trop Dis 3:e462. 2009
  10. ncbi request reprint Strategies for control of trachoma: observational study with quantitative PCR
    Anthony W Solomon
    London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK
    Lancet 362:198-204. 2003

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Operational evaluation of the use of photographs for grading active trachoma
    Anthony W Solomon
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 74:505-8. 2006
    ..Either the signs TF and TI themselves are not as reliable as previously believed, or photographs should be used for their diagnosis only when reliability testing demonstrates better agreement than found here...
  2. ncbi request reprint Lymphoma masquerading as a peritoneal dialysis catheter leak
    A W Solomon
    Department of Renal Medicine and Transplantation, Royal London Hospital, Whitechapel, London, UK
    Kidney Int 72:904. 2007
  3. ncbi request reprint Mass treatment with single-dose azithromycin for trachoma
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
    N Engl J Med 351:1962-71. 2004
    ..Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, is an important cause of blindness. Current recommended dosing intervals for mass azithromycin treatment for trachoma are based on a mathematical model...
  4. pmc Diagnosis and assessment of trachoma
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom
    Clin Microbiol Rev 17:982-1011, table of contents. 2004
    ..There is an urgent need for a rapid, reliable test for C. trachomatis to assist in measuring progress towards the elimination of trachoma...
  5. pmc Impact of mass distribution of azithromycin on the antibiotic susceptibilities of ocular Chlamydia trachomatis
    Anthony W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom
    Antimicrob Agents Chemother 49:4804-6. 2005
    ..No clinically or programmatically significant increase in azithromycin or tetracycline resistance was observed...
  6. pmc Urine output on an intensive care unit: case-control study
    Anthony W Solomon
    General Intensive Care Unit, St George s Hospital, London, UK
    BMJ 341:c6761. 2010
    ..To compare urine output between junior doctors in an intensive care unit and the patients for whom they are responsible...
  7. pmc Estimating household and community transmission of ocular Chlamydia trachomatis
    Isobel M Blake
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    PLoS Negl Trop Dis 3:e401. 2009
    ..The potential impact of more efficient, targeted treatment of infected households depends on the relative contribution of community and household transmission of infection, which have not previously been estimated...
  8. pmc Targeting antibiotics to households for trachoma control
    Isobel M Blake
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Negl Trop Dis 4:e862. 2010
    ..Here we explore whether alternative, targeted approaches are effective antibiotic-sparing strategies...
  9. pmc The development of an age-structured model for trachoma transmission dynamics, pathogenesis and control
    Manoj Gambhir
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Negl Trop Dis 3:e462. 2009
    ..We present an age-structured mathematical model of trachoma transmission and disease to predict the impact of interventions on the prevalence of blinding trachoma...
  10. ncbi request reprint Strategies for control of trachoma: observational study with quantitative PCR
    Anthony W Solomon
    London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK
    Lancet 362:198-204. 2003
    ..At present, who needs to be treated is unclear. We aimed to establish the burden of ocular Chlamydia trachomatis in three trachoma-endemic communities in Tanzania and The Gambia with real-time quantitative PCR...
  11. ncbi request reprint Participatory evaluations of trachoma control programmes in eight countries
    Hannah Kuper
    London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 10:764-72. 2005
    ..Trachoma is a major cause of blindness. The objective of this initiative was to conduct participatory process evaluations of the trachoma control programmes receiving support from the International Trachoma Initiative in eight countries...
  12. ncbi request reprint The relationship between prevalence of active trachoma, water availability and its use in a Tanzanian village
    Sarah Polack
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 100:1075-83. 2006
    ..The key element in the relationship between water availability and trachoma is the allocation of water within households. Collection time may influence both the quantity of water collected and its allocation within the household...
  13. ncbi request reprint Application of molecular tools in the control of blinding trachoma
    David Mabey
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 69:11-7. 2003
    ..In addition, the contribution of genotyping to our understanding of the epidemiology and biology of C. trachomatis is considered...
  14. ncbi request reprint Distance to water source and altitude in relation to active trachoma in Rombo district, Tanzania
    R F Baggaley
    Modelling Unit, Department of Statistics, Modelling and Bioinformatics, Centre for Infections, Health Protection Agency, London, UK
    Trop Med Int Health 11:220-7. 2006
    ..To investigate the relationship between distance to water source, altitude and active trachoma in children in Rombo district, Tanzania...
  15. ncbi request reprint Trachoma
    David C W Mabey
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK
    Lancet 362:223-9. 2003
    ..By means of the SAFE strategy, WHO and its partners aim to eliminate trachoma as a public-health problem by the year 2020...
  16. ncbi request reprint A critical review of the SAFE strategy for the prevention of blinding trachoma
    Hannah Kuper
    Clinical Research Unit, Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London, UK
    Lancet Infect Dis 3:372-81. 2003
    ..The evidence for an effect of health education and environmental improvement is weaker, and depends mostly on cross-sectional observational studies...
  17. ncbi request reprint The household distribution of trachoma in a Tanzanian village: an application of GIS to the study of trachoma
    S R Polack
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 99:218-25. 2005
    ..The association between active trachoma and geographical information system (GIS) measured distance to water may be relevant for planning control measures...
  18. ncbi request reprint An index of community ocular Chlamydia trachomatis load for control of trachoma
    N D E Alexander
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 99:175-7. 2005
    ..0.1), and in children aged six months to ten years than in the overall population (1.1 vs. 0.4). The COCTL index is potentially useful for sentinel sites, operational research and calibration of clinical measures of trachoma...
  19. doi request reprint Neglected tropical diseases
    Nick Feasey
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London, UK
    Br Med Bull 93:179-200. 2010
    ..They have been neglected for decades, initially as part of a general disregard for the developing world, and more recently due to the intensity of focus on HIV/AIDS, tuberculosis and malaria...
  20. pmc The geographical distribution and burden of trachoma in Africa
    Jennifer L Smith
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Negl Trop Dis 7:e2359. 2013
    ..This paper uses data included in the GAT to describe the geographical distribution and burden of trachoma in Africa...
  21. pmc Pilot study of the use of community volunteers to distribute azithromycin for trachoma control in Ghana
    A W Solomon
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, England
    Bull World Health Organ 79:8-14. 2001
    ..To simplify training and logistics, it may be better to base dosage schedules on height rather than weight for those taking tablets, which included most people aged four years or more in the population studied...
  22. pmc Comparing the performance of cluster random sampling and integrated threshold mapping for targeting trachoma control, using computer simulation
    Jennifer L Smith
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Negl Trop Dis 7:e2389. 2013
    ..This study uses computerised sampling simulations to compare the performance of these survey designs and evaluate the impact of varying key parameters...
  23. ncbi request reprint Antibiotic dosage in trachoma control programs: height as a surrogate for weight in children
    Beatriz Munoz
    Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Invest Ophthalmol Vis Sci 44:1464-9. 2003
    ..The purposes of this study were to determine whether an accurate dose could be determined by using height as a surrogate for weight and whether a single model of height-based dosage would be applicable in more than one setting...
  24. pmc Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates
    Harlan D Caldwell
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA
    J Clin Invest 111:1757-69. 2003
    ..We speculate that this relationship involves the production of indole by components of the vaginal microbial flora, allowing chlamydiae to escape IFN-gamma-mediated eradication and thus establish persistent infection...
  25. pmc Impact of azithromycin administration for trachoma control on the carriage of antibiotic-resistant Streptococcus pneumoniae
    Sarah L Batt
    Department of Medical Microbiology, University College London, Royal Free Campus, London NW3 2PF
    Antimicrob Agents Chemother 47:2765-9. 2003
    ..0001, Fisher's exact). These data suggest that in communities where macrolide resistance is rare, azithromycin distribution for trachoma control is unlikely to increase the prevalence of resistant organisms...
  26. ncbi request reprint Mass treatment and the effect on the load of Chlamydia trachomatis infection in a trachoma-hyperendemic community
    Emily S West
    Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Invest Ophthalmol Vis Sci 46:83-7. 2005
    ..Trachoma remains a leading cause of blindness. Determining the most effective antibiotic treatment strategy is essential for the success of country-based trachoma control programs...
  27. ncbi request reprint Acceptability of azithromycin for the control of trachoma in Northern Tanzania
    Nicola Desmond
    MRC Social and Public Health Sciences Unit, 4 Lilybank Gardens, Glasgow G12 8RG, UK
    Trans R Soc Trop Med Hyg 99:656-63. 2005
    ....
  28. doi request reprint Two doses of azithromycin to eliminate trachoma in a Tanzanian community
    Anthony W Solomon
    N Engl J Med 358:1870-1. 2008
  29. doi request reprint Absence of Mycoplasma genitalium in eye samples from a trachoma-endemic area of Tanzania
    Jacques Pepin
    Br J Ophthalmol 92:435. 2008
  30. doi request reprint Mass antibiotic administration for eradication of ocular Chlamydia trachomatis
    David Mabey
    JAMA 299:819-21. 2008
  31. ncbi request reprint Infection with Chlamydia trachomatis after mass treatment of a trachoma hyperendemic community in Tanzania: a longitudinal study
    Sheila K West
    Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, MD, USA
    Lancet 366:1296-300. 2005
    ....
  32. ncbi request reprint Chlamydial positivity of nasal discharge at baseline is associated with ocular chlamydial positivity 2 months following azithromycin treatment
    Emily West Gower
    Dana Center for Preventive Ophthalmology, 116 Wilmer Building, Johns Hopkins School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Invest Ophthalmol Vis Sci 47:4767-71. 2006
    ..Routes of transmission remain unclear. In this study, the relationship between Chlamydia trachomatis Amplicor-positive nasal discharge and Amplicor-positive ocular swabs was investigated (Amplicor; Roche, Indianapolis, IN)...
  33. pmc The SAFE strategy for trachoma control: Using operational research for policy, planning and implementation
    Paul M Emerson
    The Carter Center, Atlanta, GA 30306, USA
    Bull World Health Organ 84:613-9. 2006
    ..Operational research has become a part of practice. Although there are still many questions without answers, national programme coordinators have a reasonable expectation that trachoma control programmes based on SAFE will work...
  34. ncbi request reprint Effect of 3 years of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) strategy for trachoma control in southern Sudan: a cross-sectional study
    Jeremiah Ngondi
    Department of Public Health and Primary Care, Institute of Public Health, Cambridge, UK
    Lancet 368:589-95. 2006
    ..We did a 3-year evaluation to quantify uptake of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) interventions, and to assess the prevalence of active trachoma and unclean faces...
  35. ncbi request reprint Field evaluation of a rapid point-of-care assay for targeting antibiotic treatment for trachoma control: a comparative study
    Claude Edouard C Michel
    Diagnostics Development Unit, Department of Haematology, University of Cambridge, Cambridge, UK
    Lancet 367:1585-90. 2006
    ..Unfortunately, TF correlates poorly with C trachomatis infection. We sought to assess a newly developed point-of-care (POC) assay compared with presence of TF for guiding the use of antibiotics for trachoma control...
  36. ncbi request reprint Clinical examination versus Chlamydia trachomatis assays to guide antibiotic use in trachoma control programmes
    Anthony W Solomon
    Lancet Infect Dis 6:5-6; author reply 7-8. 2006
  37. ncbi request reprint Modeling the economic net benefit of a potential vaccination program against ocular infection with Chlamydia trachomatis
    Anthony W Solomon
    Vaccine 23:5281-2. 2005