Steven G Smith

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. ncbi Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination
    Steven G Smith
    Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, UK
    Eur J Immunol 42:2511-22. 2012
  2. ncbi Role of CD8 T cells in mycobacterial infections
    S M Smith
    Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
    Immunol Cell Biol 78:325-33. 2000
  3. ncbi Human CD8(+) T cells specific for Mycobacterium tuberculosis secreted antigens in tuberculosis patients and healthy BCG-vaccinated controls in The Gambia
    S M Smith
    Immunology Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Infect Immun 68:7144-8. 2000
  4. ncbi Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis
    Steven G Smith
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 4:e7972. 2009
  5. ncbi Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining
    Steven G Smith
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    BMC Immunol 11:35. 2010
  6. ncbi BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi
    Maeve K Lalor
    Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, United Kingdom
    J Infect Dis 204:1075-85. 2011
  7. ncbi Complex cytokine profiles induced by BCG vaccination in UK infants
    Maeve K Lalor
    Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Vaccine 28:1635-41. 2010
  8. ncbi Long-lived memory B-cell responses following BCG vaccination
    Ismail Sebina
    Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 7:e51381. 2012

Detail Information

Publications8

  1. ncbi Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination
    Steven G Smith
    Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, UK
    Eur J Immunol 42:2511-22. 2012
    ..It also suggests a number of BCG vaccination associated, HBHA-induced responses that should be useful for future studies of biomarkers of protection against TB...
  2. ncbi Role of CD8 T cells in mycobacterial infections
    S M Smith
    Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
    Immunol Cell Biol 78:325-33. 2000
    ..However, the exact protective mechanisms and antigens recognized by these important cells remain poorly characterized...
  3. ncbi Human CD8(+) T cells specific for Mycobacterium tuberculosis secreted antigens in tuberculosis patients and healthy BCG-vaccinated controls in The Gambia
    S M Smith
    Immunology Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Infect Immun 68:7144-8. 2000
    ..A change in antigen recognition was noted between the two groups of donors: in addition to recognition of Ag85A and Ag85B, as seen in healthy donors, a prominent ESAT-6 response was found in TB patients...
  4. ncbi Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis
    Steven G Smith
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 4:e7972. 2009
    ..A pre-stimulation step may improve the sensitivity of the assay, particularly when cells have been previously frozen...
  5. ncbi Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining
    Steven G Smith
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    BMC Immunol 11:35. 2010
    ..The aim of this study was to identify which cytokines and lymphocyte populations characterise the peripheral blood cellular immune response following BCG vaccination...
  6. ncbi BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi
    Maeve K Lalor
    Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, United Kingdom
    J Infect Dis 204:1075-85. 2011
    ..BCG vaccination of infants is thought to provide good protection in all settings. This study investigated whether Malawian infants made weaker responses across a cytokine panel after BCG vaccination, compared with UK infants...
  7. ncbi Complex cytokine profiles induced by BCG vaccination in UK infants
    Maeve K Lalor
    Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Vaccine 28:1635-41. 2010
    ..The pattern of cytokine induction following BCG vaccination is complex and measurement of one of two cytokines does not reveal the whole picture of vaccine-induced protection...
  8. ncbi Long-lived memory B-cell responses following BCG vaccination
    Ismail Sebina
    Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 7:e51381. 2012
    ....