I G Roberts

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. pmc CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial
    Yashbir Dewan
    Clinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Trials 13:87. 2012
  2. pmc The weight of nations: an estimation of adult human biomass
    Sarah Catherine Walpole
    North Yorkshire and East Coast deanery, 4 Hilton Place, Leeds, LS8 4HE, UK
    BMC Public Health 12:439. 2012
  3. pmc Predicting intracranial hemorrhage after traumatic brain injury in low and middle-income countries: a prognostic model based on a large, multi-center, international cohort
    Saleena Subaiya
    Department of Emergency Medicine, New York Presbyterian, New York, NY, USA
    BMC Emerg Med 12:17. 2012
  4. doi request reprint The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients
    I Roberts
    Clinical Trials Unit, London School of Hygiene and Tropical Medicine, London, UK
    Health Technol Assess 17:1-79. 2013
  5. ncbi request reprint Antifibrinolytic drugs for acute traumatic injury
    Ian Roberts
    Cochrane Injuries Group, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
    Cochrane Database Syst Rev 12:CD004896. 2012
  6. doi request reprint Barbiturates for acute traumatic brain injury
    Ian Roberts
    Cochrane Injuries Group, London School of Hygiene and Tropical Medicine, North Courtyard, KeppelStreet, London, WC1E 7HT, UK
    Cochrane Database Syst Rev 12:CD000033. 2012
  7. pmc Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial
    Ian Roberts
    London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    BMJ 345:e5839. 2012
  8. pmc Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial
    Katharine Ker
    Clinical Trials Unit, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    BMC Emerg Med 12:3. 2012
  9. pmc Between-centre differences and treatment effects in randomized controlled trials: a case study in traumatic brain injury
    Hester F Lingsma
    Department of Public Health, Erasmus MC, P, O, Box 2040, 3000 CA Rotterdam, The Netherlands
    Trials 12:201. 2011
  10. pmc Reducing the environmental impact of trials: a comparison of the carbon footprint of the CRASH-1 and CRASH-2 clinical trials
    Saleena Subaiya
    Public Health and Environment, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Trials 12:31. 2011

Detail Information

Publications88

  1. pmc CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial
    Yashbir Dewan
    Clinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Trials 13:87. 2012
    ....
  2. pmc The weight of nations: an estimation of adult human biomass
    Sarah Catherine Walpole
    North Yorkshire and East Coast deanery, 4 Hilton Place, Leeds, LS8 4HE, UK
    BMC Public Health 12:439. 2012
    ..We estimate global human biomass, its distribution by region and the proportion of biomass due to overweight and obesity...
  3. pmc Predicting intracranial hemorrhage after traumatic brain injury in low and middle-income countries: a prognostic model based on a large, multi-center, international cohort
    Saleena Subaiya
    Department of Emergency Medicine, New York Presbyterian, New York, NY, USA
    BMC Emerg Med 12:17. 2012
    ..Diagnostic capabilities and treatment options for intracranial hemorrhage are limited in LMIC as there are fewer computed tomography (CT) scanners and neurosurgeons per patient as in high-income countries...
  4. doi request reprint The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients
    I Roberts
    Clinical Trials Unit, London School of Hygiene and Tropical Medicine, London, UK
    Health Technol Assess 17:1-79. 2013
    ..In addition, the effort of tranexamic acid on the risk of vascular occlusive events was assessed...
  5. ncbi request reprint Antifibrinolytic drugs for acute traumatic injury
    Ian Roberts
    Cochrane Injuries Group, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
    Cochrane Database Syst Rev 12:CD004896. 2012
    ..Uncontrolled bleeding is an important cause of death in trauma victims. Antifibrinolytic treatment has been shown to reduce blood loss following surgery and may also be effective in reducing blood loss following trauma...
  6. doi request reprint Barbiturates for acute traumatic brain injury
    Ian Roberts
    Cochrane Injuries Group, London School of Hygiene and Tropical Medicine, North Courtyard, KeppelStreet, London, WC1E 7HT, UK
    Cochrane Database Syst Rev 12:CD000033. 2012
    ..However, barbiturates also reduce blood pressure and may, therefore, adversely effect cerebral perfusion pressure...
  7. pmc Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial
    Ian Roberts
    London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    BMJ 345:e5839. 2012
    ..To assess the extent to which current protocols for treatment with tranexamic acid maximise benefits to patients...
  8. pmc Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial
    Katharine Ker
    Clinical Trials Unit, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    BMC Emerg Med 12:3. 2012
    ..Based on data from the CRASH-2 trial, global mortality data and a systematic literature review, we estimated the number of premature deaths that might be averted every year worldwide through the use of TXA...
  9. pmc Between-centre differences and treatment effects in randomized controlled trials: a case study in traumatic brain injury
    Hester F Lingsma
    Department of Public Health, Erasmus MC, P, O, Box 2040, 3000 CA Rotterdam, The Netherlands
    Trials 12:201. 2011
    ..The aim of this study was to assess the influence of between-centre differences in outcome on the estimated treatment effect in a large RCT in TBI...
  10. pmc Reducing the environmental impact of trials: a comparison of the carbon footprint of the CRASH-1 and CRASH-2 clinical trials
    Saleena Subaiya
    Public Health and Environment, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Trials 12:31. 2011
    ..We compare the carbon emissions from two international clinical trials in order to identify where emissions reductions can be made...
  11. pmc The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury
    Haleema Shakur
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trials 10:109. 2009
    ..We evaluated the safety and effectiveness of the non-peptide bradykinin B2 receptor antagonist Anatibant in the treatment of patients with traumatic brain injury. During the course of the trial, funding was withdrawn by the sponsor...
  12. pmc The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial
    Haleema Shakur
    Clinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trials 11:40. 2010
    ..At present there is little reliable evidence from randomised trials on the effectiveness of tranexamic acid in the treatment of postpartum haemorrhage...
  13. pmc The added value of ordinal analysis in clinical trials: an example in traumatic brain injury
    Bob Roozenbeek
    Department of Neurosurgery, Antwerp University Hospital, Wilrijkstraat 10, Edegem, Belgium
    Crit Care 15:R127. 2011
    ..The objective of this study is to quantify the benefits of ordinal analysis in the real-life situation of a large TBI trial...
  14. pmc Giving tranexamic acid to reduce surgical bleeding in sub-Saharan Africa: an economic evaluation
    Carla Guerriero
    Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK
    Cost Eff Resour Alloc 8:1. 2010
    ..In countries where there is a blood shortage, TXA would be a cost effective way to reduce mortality. In countries where there is no blood shortage, TXA would reduce healthcare costs and avert blood borne infections...
  15. pmc Anti-fibrinolytic agents in post partum haemorrhage: a systematic review
    Pili Ferrer
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    BMC Pregnancy Childbirth 9:29. 2009
    ..Anti-fibrinolytic agents have been proposed as a treatment for post partum haemorrhage. We conducted a systematic review to assess the effectiveness and safety of anti-fibrinolytic agents in post partum bleeding...
  16. pmc Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury
    Pablo Perel
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    BMC Med Res Methodol 8:72. 2008
    ..The objectives of this study were to evaluate the association and predictive validity between a simple disability scale at hospital discharge, the Oxford Handicap Scale (OHS), and the GOS at 6 months among TBI patients...
  17. pmc Systematic review of prognostic models in traumatic brain injury
    Pablo Perel
    Nutrition and Public Health Intervention Research Unit, Epidemiology and Population Health Department, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    BMC Med Inform Decis Mak 6:38. 2006
    ..Two reviewers independently examined titles, abstracts and assessed whether each met the pre-defined inclusion criteria...
  18. pmc Intracranial bleeding in patients with traumatic brain injury: a prognostic study
    Pablo Perel
    Epidemiology and Population Health Department, London School of Hygiene and Tropical Medicine, London, UK
    BMC Emerg Med 9:15. 2009
    ..We analysed data from the Trauma Audit & Research Network (TARN), a large European trauma registry, to evaluate the association between the size of IB and mortality in patients with TBI...
  19. pmc Car manufacturers and global road safety: a word frequency analysis of road safety documents
    I Roberts
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Inj Prev 12:320-2. 2006
    ..However, some commentators are sceptical. The authors examined road safety policy documents to assess the extent of any bias...
  20. pmc Policy at the crossroads: climate change and injury control
    Ian Roberts
    Public Health Intervention Research Unit, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Inj Prev 13:222-3. 2007
  21. pmc Formula One and global road safety
    Ian Roberts
    London School of Hygiene and Tropical Medicine, University of London
    J R Soc Med 100:360-2. 2007
  22. pmc Climate change: the implications for policy on injury control and health promotion
    I Roberts
    Department of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK
    Inj Prev 11:326-9. 2005
  23. ncbi request reprint The health co-benefits of climate change policies: doctors have a responsibility to future generations
    Ian Roberts
    London School of Hygiene and Tropical Medicine, London
    Clin Med 9:212-3. 2009
    ..Health professionals have an urgent responsibility to ensure that the health benefits of environmental policies are understood by the public and by policymakers...
  24. pmc Doubts over head injury studies
    Ian Roberts
    London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 334:392-4. 2007
  25. ncbi request reprint Response to: The BRAIN TRIAL: a randomized, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury - authors' reply
    Ian Roberts
    Trials Co ordinating Centre, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Trials 10:111. 2009
    ....
  26. pmc The CRASH trial: the first large-scale, randomised, controlled trial in head injury
    I Roberts
    CRASH Trial Management Group, CRASH Co ordinating Centre, London School of Hygiene and Tropical Medicine, London, UK
    Crit Care 5:292-3. 2001
    ..The trial is currently recruiting, and new collaborators are welcome to join the trial (see www.crash.lshtm.ac.uk)...
  27. ncbi request reprint Propaganda or science? Biological warfare and the people of Iraq
    I G Roberts
    London School of Hygiene and Tropical Medicine, University of London WC1B 3DP, United Kingdom
    Hong Kong Med J 9:307-8. 2003
  28. pmc Does animal experimentation inform human healthcare? Observations from a systematic review of international animal experiments on fluid resuscitation
    Ian Roberts
    Cochrane Injuries Group, Public Health Intervention Research Unit, London School of Hygiene and Tropical Medicine, London WC1B 3DP
    BMJ 324:474-6. 2002
  29. pmc Walking, cycling and transport safety: an analysis of child road deaths
    Beth Sonkin
    London School of Hygiene and Tropical Medicine, UK
    J R Soc Med 99:402-5. 2006
    ..To examine trends in road death rates for child pedestrians, cyclists and car occupants...
  30. pmc Are these data real? Statistical methods for the detection of data fabrication in clinical trials
    Sanaa Al-Marzouki
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 331:267-70. 2005
    ..To test the application of statistical methods to detect data fabrication in a clinical trial...
  31. doi request reprint Txt2stop: a pilot randomised controlled trial of mobile phone-based smoking cessation support
    C Free
    Nutrition and Public Health Intervention Research Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E7HT, UK
    Tob Control 18:88-91. 2009
    ..To conduct a pilot randomised controlled trial of mobile phone-based smoking cessation support intervention for the UK population...
  32. pmc Comparison of treatment effects between animal experiments and clinical trials: systematic review
    Pablo Perel
    Crash Trials Coordinating Centre, London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 334:197. 2007
    ..To examine concordance between treatment effects in animal experiments and clinical trials. Study design Systematic review...
  33. ncbi request reprint Young men were at risk of becoming lost to follow-up in a cohort of head-injured adults
    Phil Edwards
    CRASH trials Co ordinating Centre, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    J Clin Epidemiol 60:417-24. 2007
    ..This study is to identify predictors of loss to follow-up among adults with head injury...
  34. pmc Interventions to improve water quality for preventing diarrhoea: systematic review and meta-analysis
    Thomas Clasen
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 334:782. 2007
    ..To assess the effectiveness of interventions to improve the microbial quality of drinking water for preventing diarrhoea...
  35. pmc Effectiveness of out-of-home day care for disadvantaged families: randomised controlled trial
    Tami Toroyan
    Public Health Intervention Research Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1B 3DP
    BMJ 327:906. 2003
    ..To assess the effects of providing daycare facilities for young children on the health and welfare of disadvantaged families...
  36. ncbi request reprint Policies for accelerating access to clean energy, improving health, advancing development, and mitigating climate change
    Andy Haines
    London School of Hygiene and Tropical Medicine, London, UK
    Lancet 370:1264-81. 2007
    ..Intersectoral research and concerted action, both nationally and internationally, will be required...
  37. pmc Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients
    Pablo Perel
    London School of Hygiene and Tropical Medicine, London WC1B 3DP
    BMJ 336:425-9. 2008
    ..To develop and validate practical prognostic models for death at 14 days and for death or severe disability six months after traumatic brain injury...
  38. doi request reprint How effective are some common treatments for traumatic brain injury?
    Katharine Ker
    Nutrition and Public Health Intervention Research Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
    BMJ 337:a865. 2008
  39. doi request reprint Patient outcome after traumatic brain injury in high-, middle- and low-income countries: analysis of data on 8927 patients in 46 countries
    Mary J De Silva
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK
    Int J Epidemiol 38:452-8. 2009
    ..Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide. The burden of TBI is greatest in low- and middle-income countries (LAMIC), yet little is known about patient outcomes in these settings...
  40. doi request reprint Public health benefits of strategies to reduce greenhouse-gas emissions: urban land transport
    James Woodcock
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Lancet 374:1930-43. 2009
    ....
  41. doi request reprint Public health benefits of strategies to reduce greenhouse-gas emissions: overview and implications for policy makers
    Andy Haines
    London School of Hygiene and Tropical Medicine, London, UK
    Lancet 374:2104-14. 2009
    ....
  42. doi request reprint Population adiposity and climate change
    Phil Edwards
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Int J Epidemiol 38:1137-40. 2009
    ..We estimate the impact on greenhouse gas emissions of increases in the population distribution of body mass index (BMI)...
  43. ncbi request reprint Identification of randomized controlled trials in systematic reviews: accuracy and reliability of screening records
    Phil Edwards
    Public Health Intervention Research Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, 49 51 Bedford Square, London WC1B 3DP, UK
    Stat Med 21:1635-40. 2002
    ..Two reviewers should screen records for eligibility, whenever possible, in order to maximize ascertainment of relevant trials...
  44. ncbi request reprint The development of a register of randomized controlled trials in prehospital trauma care
    Irene Kwan
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, United Kingdom
    Prehosp Emerg Care 6:27-30. 2002
    ..To establish a register of randomized controlled trials of interventions in the prehospital care of trauma patients...
  45. pmc Prevalence of working smoke alarms in local authority inner city housing: randomised controlled trial
    Diane Rowland
    Public Health Intervention Research Unit, London School of Hygiene and Tropical Medicine, London WC1B 3DP
    BMJ 325:998-1001. 2002
    ..To identify which type of smoke alarm is most likely to remain working in local authority inner city housing, and to identify an alarm tolerated in households with smokers...
  46. ncbi request reprint Prevention of deaths and injuries caused by house fires: survey of local authority smoke alarm policies
    Diane Rowland
    Public Health Intervention Research Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, 49 51 Bedford Square, London WC1B 3DP
    J Public Health Med 24:217-8. 2002
    ..However, the extent to which local authorities comply is currently not known. We conducted a survey of local authorities to establish the extent of their smoke alarm provision to public sector households...
  47. ncbi request reprint Follow-up by mail in clinical trials: does questionnaire length matter?
    Phil Edwards
    CRASH Trial Co ordinating Centre, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, 49 51 Bedford Square London, WC1B 3DP, UK
    Control Clin Trials 25:31-52. 2004
    ..If a new follow-up questionnaire is to be designed, it should be made as short as possible without compromising the data collection requirements of the trial...
  48. pmc Increasing response rates to postal questionnaires: systematic review
    Phil Edwards
    CRASH Trial Co ordinating Centre, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1B 1DP
    BMJ 324:1183. 2002
    ..To identify methods to increase response to postal questionnaires...
  49. ncbi request reprint Post-licence driver education for the prevention of road traffic crashes: a systematic review of randomised controlled trials
    Katharine Ker
    Nutrition and Public Health Intervention Research Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Accid Anal Prev 37:305-13. 2005
    ..Although the results are compatible with a small reduction in the occurrence of traffic crashes, this may be due to selection biases or bias in the included trials...
  50. ncbi request reprint The effect of scientific misconduct on the results of clinical trials: a Delphi survey
    Sanaa Al-Marzouki
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, 49 51 Bedford Square, London, WC1B 3DP, United Kingdom
    Contemp Clin Trials 26:331-7. 2005
    ..To discover what types of scientific misconduct are most likely to influence the results of a clinical trial...
  51. ncbi request reprint Energy and transport
    James Woodcock
    London School of Hygiene and Tropical Medicine, London, UK
    Lancet 370:1078-88. 2007
    ..There exists the potential for a global contraction and convergence in use of fossil-fuel energy for transport to benefit health and achieve sustainability...
  52. pmc Deaths from injury in children and employment status in family: analysis of trends in class specific death rates
    Phil Edwards
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 333:119. 2006
    ..To examine socioeconomic inequalities in rates of death from injury in children in England and Wales...
  53. pmc Meta-analysis of randomised trials of monetary incentives and response to mailed questionnaires
    Phil Edwards
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    J Epidemiol Community Health 59:987-99. 2005
    ..To quantify the increase in mailed questionnaire response attributable to a monetary incentive...
  54. doi request reprint Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
    Haleema Shakur
    Clinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Lancet 376:23-32. 2010
    ..We assessed the effects of early administration of a short course of tranexamic acid on death, vascular occlusive events, and the receipt of blood transfusion in trauma patients...
  55. ncbi request reprint Sex workers' accounts of condom use: implications for condom production, promotion and health policy
    Caroline Free
    Nutrition and Public Health Interventions Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    J Fam Plann Reprod Health Care 33:107-11. 2007
    ..To explore sex workers' accounts of condom use and their recommendations about how condoms might be improved...
  56. ncbi request reprint CRASH trial: the first large-scale randomized controlled trial in head injury
    Ian Roberts
    CRASH Trial Coordinating Centre, London School of Hygiene and Tropical Medicine, London, UK
    ANZ J Surg 72:600. 2002
  57. ncbi request reprint Prognosis following head injury: a survey of doctors from developing and developed countries
    Pablo Perel
    J Eval Clin Pract 13:464-5. 2007
  58. ncbi request reprint The CRASH-2 trial of an antifibrinolytic agent in traumatic haemorrhage: an international collaboration
    Ian Roberts
    Indian J Med Res 125:5-7. 2007
  59. ncbi request reprint Systematic reviews of animal experiments
    Peter Sandercock
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh EH4 2XU, UK
    Lancet 360:586. 2002
  60. ncbi request reprint Fluid resuscitation strategies: a systematic review of animal trials
    James Mapstone
    Public Health Medicine, Castle Point and Rochford Primary Care Trust, Rayleigh, Essex, United Kingdom
    J Trauma 55:571-89. 2003
    ..Our objective was to systematically review randomized, controlled trials of fluid resuscitation in animal models of uncontrolled hemorrhage and to explore potential sources of heterogeneity...
  61. ncbi request reprint Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial
    Ian Roberts
    Lancet 364:1321-8. 2004
    ..In May, 2004, the data monitoring committee disclosed the unmasked results to the steering committee, which stopped recruitment...
  62. ncbi request reprint Determining the cost effectiveness of a smoke alarm give-away program using data from a randomized controlled trial
    Laura Ginnelly
    Centre for Health Economics, University of York, York, UK
    Eur J Public Health 15:448-53. 2005
    ..In 2001 in the US, there were 383 500 home fires, resulting in 3110 deaths, 15,200 injuries and dollar 5.5 billion in direct property damage...
  63. pmc Congestion charging and the walking classes
    Ian Roberts
    BMJ 326:345-6. 2003
  64. pmc War on the roads
    Ian Roberts
    BMJ 324:1107-8. 2002
  65. pmc Safety education of pedestrians for injury prevention: a systematic review of randomised controlled trials
    Olivier Duperrex
    Institut de Medecine Sociale et Preventive, CMU, CH 1211 Geneva 4, Switzerland
    BMJ 324:1129. 2002
    ..To quantify the effectiveness of safety education of pedestrians...
  66. ncbi request reprint Biological warfare and the people of Iraq
    Ian Roberts
    Int J Epidemiol 32:660-1. 2003
  67. pmc Where is the evidence that animal research benefits humans?
    Pandora Pound
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 328:514-7. 2004
  68. ncbi request reprint The CRASH trial: the first large-scale randomized controlled trial in head injury. Corticosteroid Randomization After Significant Head injury
    Ian Roberts
    Natl Med J India 15:61-2. 2002
  69. pmc Crash
    Ian Roberts
    J R Soc Med 95:162. 2002
  70. pmc Antifibrinolytic agents in traumatic hemorrhage
    Tim Coats
    University of Leicester, Leicester, United Kingdom
    MedGenMed 7:9. 2005
  71. pmc Reducing the carbon footprint of medical conferences
    Ian Roberts
    BMJ 334:324-5. 2007
  72. ncbi request reprint Egg on their faces. The story of human albumin solution
    Ian Roberts
    Eval Health Prof 25:130-8. 2002
    ....
  73. ncbi request reprint PFI is here to stay. Select committee's report used parliamentary privilege unacceptably
    Alison Macfarlane
    BMJ 324:1584. 2002
  74. ncbi request reprint Use of weapons of mass destruction
    Ian Roberts
    Lancet 361:786. 2003
  75. ncbi request reprint International IgA nephropathy network clinico-pathological classification of IgA nephropathy
    John Feehally
    The John Walls Renal Unit, Leicester General Hospital, Leicester, UK
    Contrib Nephrol 157:13-8. 2007
    ..The goal is to establish a reproducible and clinically effective classification which will gain worldwide acceptance for use in clinical practice and research...
  76. ncbi request reprint Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months
    Phil Edwards
    Lancet 365:1957-9. 2005
    ..These results lend support to our earlier conclusion that corticosteroids should not be used routinely in the treatment of head injury...
  77. pmc Surveying the literature from animal experiments: systematic review and meta-analysis are important contributions
    Malcolm R Macleod
    BMJ 331:110. 2005
  78. pmc The economics of tackling climate change
    Ian Roberts
    BMJ 336:165-6. 2008
  79. pmc Antifibrinolytic agents in traumatic haemorrhage
    Tim Coats
    University of Leicester, Leicester, United Kingdom
    PLoS Med 2:e64. 2005
  80. doi request reprint Randomized trials in vulnerable populations
    Deborah Cook
    Department of Medicine, McMaster University Health Sciences Center, Hamilton, Ontario, Canada
    Clin Trials 5:61-9. 2008
    ....
  81. ncbi request reprint Antifibrinolytic agents in traumatic hemorrhage: a large scale randomized controlled trial is needed
    Tim Coats
    Croat Med J 46:146-7. 2005
  82. pmc War on the roads: two years on
    Ian Roberts
    BMJ 328:845. 2004
  83. pmc Saddam Hussein's medical examination should not have been broadcast: images were designed to humiliate
    Ian Roberts
    BMJ 328:51. 2004
  84. doi request reprint Transport policy is food policy
    Phil Edwards
    Lancet 371:1661. 2008
  85. pmc War in Iraq: medical journals and the manufacture of consent
    Ian Roberts
    J Natl Med Assoc 95:628-9. 2003
  86. pmc Trauma care research and the war on uncertainty
    Ian Roberts
    BMJ 331:1094-6. 2005
  87. pmc Incidence of fires and related injuries after giving out free smoke alarms: cluster randomised controlled trial
    Carolyn DiGuiseppi
    Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Campus Box B 119, Denver, CO 80262, USA
    BMJ 325:995. 2002
    ..To measure the effect of giving out free smoke alarms on rates of fires and rates of fire related injury in a deprived multiethnic urban population...