Research Topics
| Frank MwaunguluSummaryAffiliation: London School of Hygiene and Tropical Medicine Country: UK Publications
| Collaborators
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Detail Information
Publications
Differences between naive and memory T cell phenotype in Malawian and UK adolescents: a role for Cytomegalovirus?Anne Ben-Smith
Department of Infectious and Tropical Diseases, Keppel Street, London WC1E7HT, UK
BMC Infect Dis 8:139. 2008....
Reverse transcriptase drug resistance mutations in HIV-1 subtype C infected patients on ART in Karonga District, MalawiVijay B Bansode
Molecular Evolution and Systematics Laboratory, Zoology, Ryan Institute, School of Natural Sciences, National University of Ireland, Galway, Ireland
AIDS Res Ther 8:38. 2011..abstract:..
Recurrent TB: relapse or reinfection? The effect of HIV in a general population cohort in MalawiAmelia C Crampin
Karonga Prevention Study, Chilumba, Malawi
AIDS 24:417-26. 2010..To estimate rates of recurrent tuberculosis due to reinfection and relapse, by HIV status, in a general population...
What has Karonga taught us? Tuberculosis studied over three decadesA C Crampin
London School of Hygiene and Tropical Medicine, London, UK
Int J Tuberc Lung Dis 13:153-64. 2009..Current studies focus on immunological markers of infection, disease and protection, and on elucidating the impact of antiretroviral treatment on TB incidence at population level...
Assessment and evaluation of contact as a risk factor for tuberculosis in rural AfricaA C Crampin
Karonga Prevention Study, Chilumba, Malawi
Int J Tuberc Lung Dis 12:612-8. 2008..A rural district in Malawi...
Use of antenatal clinic surveillance to assess the effect of sexual behavior on HIV prevalence in young women in Karonga district, MalawiAmelia Catharine Crampin
Department of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
J Acquir Immune Defic Syndr 48:196-202. 2008..Sexual behavior monitoring to explain HIV distribution and trends is seldom attempted in ANC surveys. We explore the use of marital history in ANC surveillance as a proxy for sexual behavior...
What happens to ART-eligible patients who do not start ART? Dropout between screening and ART initiation: a cohort study in Karonga, MalawiNuala McGrath
London School of Hygiene and Tropical Medicine, London, UK
BMC Public Health 10:601. 2010..We aimed to investigate the outcome of those who are eligible but do not start ART in the Malawi programme, factors associated with this dropout, and reasons for not starting treatment, in a prospective cohort study...
Comparison of two versus three smears in identifying culture-positive tuberculosis patients in a rural African setting with high HIV prevalenceA C Crampin
Karonga Prevention Study, Chilumba, Malawi
Int J Tuberc Lung Dis 5:994-9. 2001..The potential for improving specificity is important because of the costs of misdiagnosis. In practice, both sensitivity and specificity may be increased due to the time saved by examining two rather than three smears...
Population-level effect of HIV on adult mortality and early evidence of reversal after introduction of antiretroviral therapy in MalawiAndreas Jahn
London School of Hygiene and Tropical Medicine, London, UK
Lancet 371:1603-11. 2008..We aimed to investigate mortality in a population before and after the introduction of free antiretroviral therapy, and therefore to assess the effects of such programmes on survival at the population level...
Tuberculosis and gender: exploring the patterns in a case control study in MalawiA C Crampin
Karonga Prevention Study, Chilumba, Malawi
Int J Tuberc Lung Dis 8:194-203. 2004..CONCLUSIONS: In this population, HIV infection and contacts with known tuberculosis patients are important determinants of the gender distribution of cases...
Herpes simplex virus type 2 trends in relation to the HIV epidemic in northern MalawiJ R Glynn
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E7HT, UK
Sex Transm Infect 84:356-60. 2008..HSV-2 prevalence trends in a rural African community were assessed over a period in which HIV prevalence rose sharply, and antenatal clinic (ANC) surveillance was explored as a method of estimating community HSV-2 prevalence...
Human immunodeficiency virus increases the risk of tuberculosis due to recent re-infection in individuals with latent infectionR M G J Houben
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, UK
Int J Tuberc Lung Dis 14:909-15. 2010..tuberculosis. If contemporary TB cases share identical M. tuberculosis strains (i.e., are 'clustered'), the episode is likely to have followed recent (re-)infection, irrespective of evidence of previous latent infection...
Ascertainment of childhood vaccination histories in northern MalawiA Jahn
Karonga Prevention Study, Chilumba, Malawi
Trop Med Int Health 13:129-38. 2008..To assess factors related to recorded vaccine uptake, which may confound the evaluation of vaccine impact...
The development of the HIV epidemic in Karonga District, MalawiJ R Glynn
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
AIDS 15:2025-9. 2001..To investigate the prevalence and sociodemographic risk factors for HIV infection, during the early stages of the epidemic, in a rural area of northern Malawi...
Field-based random sampling without a sampling frame: control selection for a case-control study in rural AfricaA C Crampin
London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
Trans R Soc Trop Med Hyg 95:481-3. 2001..We also present an audit of the selection process, and discuss the potential of this method in other settings...
Tuberculosis: associations with HIV and socioeconomic status in rural MalawiJ R Glynn
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Trans R Soc Trop Med Hyg 94:500-3. 2000..Increased risks of TB with age and in men are expected. Associations with measures of higher socioeconomic status were unexpected. They may reflect a greater likelihood of diagnosis in this group...
Lymphatic filariasis in the Karonga district of northern Malawi: a prevalence surveyB M M Ngwira
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
Ann Trop Med Parasitol 96:137-44. 2002..The W. bancrofti infection focus in Karonga district is therefore wider than was previously known. This has important implications for the implementation and eventual impact of LF-control activities in this area...
HIV epidemic trend and antiretroviral treatment need in Karonga District, MalawiR G White
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, UK
Epidemiol Infect 135:922-32. 2007..1% of adults were in need of ART in 2005. This prediction was sensitive to the assumed eligibility period, ranging from 1.6% to 2.6% if the eligibility period was instead assumed to be 1.5 or 2.5 years, respectively...
The social and economic impact of parental HIV on children in northern Malawi: retrospective population-based cohort studyS Floyd
London School of Hygiene and Tropical Medicine, London, UK
AIDS Care 19:781-90. 2007....
Human immunodeficiency virus associated tuberculosis more often due to recent infection than reactivation of latent infectionR M G J Houben
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, UK
Int J Tuberc Lung Dis 15:24-31. 2011..As HIV-positive TB cases are less likely to be source cases, equal or higher clustering in HIV-positives would suggest that HIV mainly increases the risk of TB following recent infection...
Patterns of helminth infection and relationship to BCG vaccination in Karonga District, northern MalawiA E Randall
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Trans R Soc Trop Med Hyg 96:29-33. 2002....
The influence of previous exposure to environmental mycobacteria on the interferon-gamma response to bacille Calmette-Guérin vaccination in southern England and northern MalawiR E Weir
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
Clin Exp Immunol 146:390-9. 2006..These observations should assist the development and interpretation of human clinical trials of new vaccines against M. tuberculosis in areas of both low and high exposure to environmental mycobacteria...
Patterns and implications of naturally acquired immune responses to environmental and tuberculous mycobacterial antigens in northern MalawiG F Black
Karonga Prevention Study, Chilumba, Malawi
J Infect Dis 184:322-9. 2001..Although not statistically significant, the trend is consistent with the hypothesis that prior exposure to environmental mycobacteria interferes with immune responses to BCG vaccination...
