P McKeigue

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. pmc Mapping genes underlying ethnic differences in disease risk by linkage disequilibrium in recently admixed populations
    P M McKeigue
    Epidemiology Unit, Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine, United Kingdom
    Am J Hum Genet 60:188-96. 1997
  2. ncbi request reprint Metabolic syndrome and coronary heart disease in South Asians, African-Caribbeans and white Europeans: a UK population-based cross-sectional study
    T Tillin
    National Heart and Lung Institute, Imperial College St Mary s Campus, 59 61 North Wharf Road, London, W2 1LA, UK
    Diabetologia 48:649-56. 2005
  3. pmc Design and analysis of admixture mapping studies
    C J Hoggart
    Noncommunicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom
    Am J Hum Genet 74:965-78. 2004
  4. ncbi request reprint Admixture in the Hispanics of the San Luis Valley, Colorado, and its implications for complex trait gene mapping
    C Bonilla
    National Human Genome Center, Howard University, Washington, DC 20060, USA
    Ann Hum Genet 68:139-53. 2004
  5. ncbi request reprint Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population
    M Molokhia
    Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Hum Genet 112:310-8. 2003
  6. pmc Population structure in admixed populations: effect of admixture dynamics on the pattern of linkage disequilibrium
    C L Pfaff
    Department of Anthropology, Pennsylvania State University, University Park, PA, 16802, USA
    Am J Hum Genet 68:198-207. 2001
  7. ncbi request reprint Malaria susceptibility and CD36 mutation
    T J Aitman
    MRC Clinical Sciences Centre, and Imperial College Genetics and Genomics Research Institute, Hammersmith Hospital, London, UK
    Nature 405:1015-6. 2000
  8. pmc Relation of type 2 diabetes to individual admixture and candidate gene polymorphisms in the Hispanic American population of San Luis Valley, Colorado
    E J Parra
    J Med Genet 41:e116. 2004
  9. ncbi request reprint Do known risk factors explain the higher coronary heart disease mortality in South Asian compared with European men? Prospective follow-up of the Southall and Brent studies, UK
    N G Forouhi
    MRC Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
    Diabetologia 49:2580-8. 2006
  10. ncbi request reprint Cardiovascular disease mortality in relation to childhood and adulthood socioeconomic markers in British South Asian men
    T Tillin
    International Centre for Circulatory Health, Imperial College, St Mary s and Hammersmith Hospitals, 59 61 North Wharf Road, London W2 1LA, UK
    Heart 94:476-81. 2008

Detail Information

Publications10

  1. pmc Mapping genes underlying ethnic differences in disease risk by linkage disequilibrium in recently admixed populations
    P M McKeigue
    Epidemiology Unit, Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine, United Kingdom
    Am J Hum Genet 60:188-96. 1997
    ..This approach has greater statistical power than allele-sharing designs and has obvious applications to the genetics of hypertension, non-insulin-dependent diabetes, and obesity...
  2. ncbi request reprint Metabolic syndrome and coronary heart disease in South Asians, African-Caribbeans and white Europeans: a UK population-based cross-sectional study
    T Tillin
    National Heart and Lung Institute, Imperial College St Mary s Campus, 59 61 North Wharf Road, London, W2 1LA, UK
    Diabetologia 48:649-56. 2005
    ..The aim of this study was to study differences in the prevalence of the metabolic syndrome and its associations with prevalent CHD according to ethnicity and sex...
  3. pmc Design and analysis of admixture mapping studies
    C J Hoggart
    Noncommunicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom
    Am J Hum Genet 74:965-78. 2004
    ....
  4. ncbi request reprint Admixture in the Hispanics of the San Luis Valley, Colorado, and its implications for complex trait gene mapping
    C Bonilla
    National Human Genome Center, Howard University, Washington, DC 20060, USA
    Ann Hum Genet 68:139-53. 2004
    ..082, p < 0.001). We discuss the implications of these findings in disease gene mapping efforts...
  5. ncbi request reprint Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population
    M Molokhia
    Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Hum Genet 112:310-8. 2003
    ..This conclusion lays a basis for localizing the genes underlying this ethnic difference in risk of SLE by admixture mapping...
  6. pmc Population structure in admixed populations: effect of admixture dynamics on the pattern of linkage disequilibrium
    C L Pfaff
    Department of Anthropology, Pennsylvania State University, University Park, PA, 16802, USA
    Am J Hum Genet 68:198-207. 2001
    ....
  7. ncbi request reprint Malaria susceptibility and CD36 mutation
    T J Aitman
    MRC Clinical Sciences Centre, and Imperial College Genetics and Genomics Research Institute, Hammersmith Hospital, London, UK
    Nature 405:1015-6. 2000
  8. pmc Relation of type 2 diabetes to individual admixture and candidate gene polymorphisms in the Hispanic American population of San Luis Valley, Colorado
    E J Parra
    J Med Genet 41:e116. 2004
  9. ncbi request reprint Do known risk factors explain the higher coronary heart disease mortality in South Asian compared with European men? Prospective follow-up of the Southall and Brent studies, UK
    N G Forouhi
    MRC Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
    Diabetologia 49:2580-8. 2006
    ..We examined prospectively whether measured risk factors can explain the higher CHD mortality in South Asians compared with Europeans...
  10. ncbi request reprint Cardiovascular disease mortality in relation to childhood and adulthood socioeconomic markers in British South Asian men
    T Tillin
    International Centre for Circulatory Health, Imperial College, St Mary s and Hammersmith Hospitals, 59 61 North Wharf Road, London W2 1LA, UK
    Heart 94:476-81. 2008
    ..To study the effects of childhood and adulthood socioeconomic position (SEP) including length of education on rates of cardiovascular disease (CVD) mortality in British South Asians...