Anneke C Hesseling

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. ncbi request reprint The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children
    Anneke C Hesseling
    Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, P O Box 19063, Tygerberg, 7505, South Africa
    Vaccine 25:14-8. 2007
  2. pmc Culture-confirmed childhood tuberculosis in Cape Town, South Africa: a review of 596 cases
    H Simon Schaaf
    Desmond Tutu Tuberculosis Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa
    BMC Infect Dis 7:140. 2007
  3. ncbi request reprint Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis
    Freda Maree
    Desmond Tutu TB Centre, Department of Pediatrics and Child Health, Stellenbosch University, Stellenbosch, South Africa
    Pediatr Infect Dis J 26:13-8. 2007
  4. doi request reprint Hearing loss in children treated for multidrug-resistant tuberculosis
    James A Seddon
    Desmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, South Africa
    J Infect 66:320-9. 2013
  5. ncbi request reprint Childhood drug-resistant tuberculosis in the Western Cape Province of South Africa
    H Simon Schaaf
    Department of Paediatrics and Child Health, Tygerberg Children s Hospital and Stellenbosh University, Tygerberg, South Africa
    Acta Paediatr 95:523-8. 2006
  6. doi request reprint Use of light-emitting diode fluorescence microscopy to detect acid-fast bacilli in sputum
    Ben J Marais
    Desmond Tutu TB Centre, Cape Town, South Africa
    Clin Infect Dis 47:203-7. 2008
  7. ncbi request reprint Radiographic signs and symptoms in children treated for tuberculosis: possible implications for symptom-based screening in resource-limited settings
    Ben J Marais
    Desmond Tutu TB Centre and the Department of Paediatrics and Child Health, Tygerberg Children s Hospital, Stellenbosch University, Cape Town, South Africa
    Pediatr Infect Dis J 25:237-40. 2006
  8. doi request reprint Paediatric use of second-line anti-tuberculosis agents: a review
    James A Seddon
    Desmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, South Africa
    Tuberculosis (Edinb) 92:9-17. 2012
  9. ncbi request reprint A refined symptom-based approach to diagnose pulmonary tuberculosis in children
    Ben J Marais
    Desmond Tutu Tuberculosis Centre and Department of Paediatrics and Child Health, Tygerberg Children s Hospital, Stellenbosch University, Cape Town, South Africa
    Pediatrics 118:e1350-9. 2006
  10. ncbi request reprint Recurrent culture-confirmed tuberculosis in human immunodeficiency virus-infected children
    H Simon Schaaf
    Department of Paediatrics and Child Health, Stellenbosch University, Tygerberg, South Africa
    Pediatr Infect Dis J 24:685-91. 2005

Detail Information

Publications25

  1. ncbi request reprint The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children
    Anneke C Hesseling
    Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, P O Box 19063, Tygerberg, 7505, South Africa
    Vaccine 25:14-8. 2007
    ..We estimate the risk of disseminated BCG disease in HIV-infected children in a setting highly endemic for tuberculosis and HIV...
  2. pmc Culture-confirmed childhood tuberculosis in Cape Town, South Africa: a review of 596 cases
    H Simon Schaaf
    Desmond Tutu Tuberculosis Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa
    BMC Infect Dis 7:140. 2007
    ..The clinical, radiological and microbiological features of culture-confirmed childhood tuberculosis diagnosed at two referral hospitals are described...
  3. ncbi request reprint Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis
    Freda Maree
    Desmond Tutu TB Centre, Department of Pediatrics and Child Health, Stellenbosch University, Stellenbosch, South Africa
    Pediatr Infect Dis J 26:13-8. 2007
    ..We investigated mycobacterial genotypic diversity in children with TBM and analyzed the relationship among genotype, clinical presentation and outcome...
  4. doi request reprint Hearing loss in children treated for multidrug-resistant tuberculosis
    James A Seddon
    Desmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, South Africa
    J Infect 66:320-9. 2013
    ..Both classes of drug cause hearing loss. We aimed to determine the extent of hearing loss in children treated for MDR-TB...
  5. ncbi request reprint Childhood drug-resistant tuberculosis in the Western Cape Province of South Africa
    H Simon Schaaf
    Department of Paediatrics and Child Health, Tygerberg Children s Hospital and Stellenbosh University, Tygerberg, South Africa
    Acta Paediatr 95:523-8. 2006
    ..Continued surveillance of drug resistance amongst children presenting with culture-confirmed tuberculosis to a tertiary care hospital and to community clinics...
  6. doi request reprint Use of light-emitting diode fluorescence microscopy to detect acid-fast bacilli in sputum
    Ben J Marais
    Desmond Tutu TB Centre, Cape Town, South Africa
    Clin Infect Dis 47:203-7. 2008
    ..We evaluated the diagnostic performance of fluorescence microscopy, using novel light-emitting diode (LED) technology as an alternative to the conventional mercury vapor lamp (MVP)...
  7. ncbi request reprint Radiographic signs and symptoms in children treated for tuberculosis: possible implications for symptom-based screening in resource-limited settings
    Ben J Marais
    Desmond Tutu TB Centre and the Department of Paediatrics and Child Health, Tygerberg Children s Hospital, Stellenbosch University, Cape Town, South Africa
    Pediatr Infect Dis J 25:237-40. 2006
    ....
  8. doi request reprint Paediatric use of second-line anti-tuberculosis agents: a review
    James A Seddon
    Desmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, South Africa
    Tuberculosis (Edinb) 92:9-17. 2012
    ..This article reviews the available second-line drugs currently used in the treatment of MDR-TB in children and discusses medication properties and adverse effects while potential interactions with antiretroviral therapy are explored...
  9. ncbi request reprint A refined symptom-based approach to diagnose pulmonary tuberculosis in children
    Ben J Marais
    Desmond Tutu Tuberculosis Centre and Department of Paediatrics and Child Health, Tygerberg Children s Hospital, Stellenbosch University, Cape Town, South Africa
    Pediatrics 118:e1350-9. 2006
    ..This study aimed to determine the value of well-defined symptoms to diagnose childhood pulmonary tuberculosis in a tuberculosis-endemic area...
  10. ncbi request reprint Recurrent culture-confirmed tuberculosis in human immunodeficiency virus-infected children
    H Simon Schaaf
    Department of Paediatrics and Child Health, Stellenbosch University, Tygerberg, South Africa
    Pediatr Infect Dis J 24:685-91. 2005
    ..Recurrent tuberculosis (TB) is more common among human immunodeficiency virus (HIV)-infected than HIV-uninfected adults. There are limited data regarding recurrence of TB in children...
  11. ncbi request reprint A proposed radiological classification of childhood intra-thoracic tuberculosis
    Ben J Marais
    Department of Paediatrics and Child Health, Centre for TB Research and Education CENTRE, Faculty of Health Sciences, University of Stellenbosch, Tygerberg, PO Box 19063, Cape Town, South Africa
    Pediatr Radiol 34:886-94. 2004
    ..The hope is that the proposed classification will clarify concepts and stimulate discussion that may lead to future consensus...
  12. pmc Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a high-burden setting perspective
    Susan S van Wyk
    Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa
    BMC Public Health 11:544. 2011
    ..We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case...
  13. pmc Surveillance of antituberculosis drug resistance among children from the Western Cape Province of South Africa--an upward trend
    H Simon Schaaf
    Desmond Tutu Tuberculosis Centre, Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa
    Am J Public Health 99:1486-90. 2009
    ..We assessed the prevalence of antituberculosis drug resistance among children with tuberculosis (TB) in the Western Cape Province of South Africa...
  14. doi request reprint A proposed comprehensive classification of tuberculosis disease severity in children
    Catherine A Wiseman
    Desmond Tutu TB Centre, Department of Pediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa
    Pediatr Infect Dis J 31:347-52. 2012
    ..There is no existing approach that comprehensively characterizes the spectrum and severity of pediatric TB. This limits accurate classification of patients and comparison across cohorts...
  15. ncbi request reprint Resistant Mycobacterium bovis Bacillus Calmette-Guérin disease: implications for management of Bacillus Calmette-Guérin Disease in human immunodeficiency virus-infected children
    Anneke C Hesseling
    Center for Tuberculosis Research and Education, Department of Pediatrics and Child Health, Tygerberg Children s Hospital, Tygerberg, South Africa
    Pediatr Infect Dis J 23:476-9. 2004
    ..Treatment guidelines for BCG disease with consideration of inherent and possible acquired drug resistance should be established in settings with high rates of vertical HIV transmission and routine BCG vaccination...
  16. pmc Beijing and Haarlem genotypes are overrepresented among children with drug-resistant tuberculosis in the Western Cape Province of South Africa
    Ben J Marais
    Ukwanda Centre for Rural Health, Faculty of Health Sciences, Stellenbosch University, P O Box 19063, Tygerberg 7505, South Africa
    J Clin Microbiol 44:3539-43. 2006
    ..The overrepresentation of Beijing and Haarlem genotype families in children with drug-resistant TB demonstrates their contribution to transmitted drug resistance and their potential importance in the emergent drug-resistant TB epidemic...
  17. doi request reprint Culture-confirmed multidrug-resistant tuberculosis in children: clinical features, treatment, and outcome
    James A Seddon
    Desmond Tutu Tuberculosis Centre, Faculty of Health Sciences, Stellenbosch University, South Africa
    Clin Infect Dis 54:157-66. 2012
    ..Multidrug-resistant (MDR) tuberculosis in children is frequently associated with delayed diagnosis and treatment. There is limited evidence regarding the management and outcome of children with MDR-tuberculosis...
  18. pmc Does an isoniazid prophylaxis register improve tuberculosis contact management in South african children?
    Nelda van Soelen
    Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, Western Cape, South Africa
    PLoS ONE 8:e80803. 2013
    ..We compared the change in child household contact management of pulmonary tuberculosis (TB) cases before and after the implementation of an isoniazid preventive therapy (IPT) register in an urban clinic setting in Cape Town, South Africa...
  19. doi request reprint Hearing loss in patients on treatment for drug-resistant tuberculosis
    James A Seddon
    Desmond Tutu TB Centre, Dept of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa
    Eur Respir J 40:1277-86. 2012
    ..Finally it makes the recommendation that a standardised testing methodology and classification system should be used...
  20. pmc Effect of Ascaris Lumbricoides specific IgE on tuberculin skin test responses in children in a high-burden setting: a cross-sectional community-based study
    Nelda van Soelen
    Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa
    BMC Infect Dis 12:211. 2012
    ..Our aim was to investigate whether helminth infection could influence the ability to generate an appropriate Th1 immune response that is characterized by a positive tuberculin skin test (TST), in M.tb exposed children...
  21. pmc Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting
    Novel N Chegou
    DST NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa
    PLoS ONE 8:e64226. 2013
    ..tb) infection states. In this study, the utility of such markers was investigated in children screened for TB in a setting with high TB incidence...
  22. pmc Risk factors for infection and disease in child contacts of multidrug-resistant tuberculosis: a cross-sectional study
    James A Seddon
    Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Clinical Building, Room 0085, P, O, Box 19063, Tygerberg, South Africa
    BMC Infect Dis 13:392. 2013
    ..This study aimed to determine risk factors for M. tuberculosis infection and disease in children following exposure to adults with multidrug-resistant (MDR) tuberculosis (TB)...
  23. doi request reprint Making BCG vaccination programmes safer in the HIV era
    Tippi K Mak
    Department of Public Health and Epidemiology, Swiss Tropical Institute, CH 4002 Basel, Switzerland
    Lancet 372:786-7. 2008
  24. ncbi request reprint Scoring systems for the diagnosis of childhood tuberculosis: are we making progress?
    Anneke C Hesseling
    Int J Tuberc Lung Dis 11:245. 2007
  25. ncbi request reprint Tuberculous lymphadenitis as a cause of persistent cervical lymphadenopathy in children from a tuberculosis-endemic area
    Ben J Marais
    Desmond Tutu TB Center and Department of Paediatrics and Child Health, Tygerberg Children s Hospital, Cape Town, South Africa
    Pediatr Infect Dis J 25:142-6. 2006
    ....