Research Topics
| R GrieveSummaryAffiliation: London School of Hygiene and Tropical Medicine Country: UK Publications
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Detail Information
Publications
A cost-effectiveness analysis of rhDNase in children with cystic fibrosisRichard Grieve
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, UK
Int J Technol Assess Health Care 19:71-9. 2003..This study compared the relative cost-effectiveness of daily recombinant human deoxyribonuclease (rhDNase), with alternate day rhDNase and hypertonic saline (HS) for treating children with cystic fibrosis (CF)...
Is Drotrecogin alfa (activated) for adults with severe sepsis, cost-effective in routine clinical practice?M Zia Sadique
Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, 15 17 Tavistock Place, London, WC1H 9SH, UK
Crit Care 15:R228. 2011..There is little evidence on whether DrotAA is cost-effective in routine clinical practice. We assessed whether DrotAA is cost-effective in routine practice for adult patients with severe sepsis and multiple organ systems failing...- Cost-Effectiveness and Resource Allocation (CERA) - directions for the futureRob Baltussen
Department of Community and Primary Care, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Cost Eff Resour Alloc 7:14. 2009.... - Control of hyperglycaemia in paediatric intensive care (CHiP): study protocolDuncan Macrae
Paediatric Intensive Care Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
BMC Pediatr 10:5. 2010..Children show similar hyperglycaemic responses to surgery or critical illness. However it is not known whether tight control will benefit children given maturational differences and different disease spectrum... 
Bayesian hierarchical models for cost-effectiveness analyses that use data from cluster randomized trialsRichard Grieve
Health Services Research Unit, London School of Hygiene and Tropical Medicine, London, UK
Med Decis Making 30:163-75. 2010..The authors conclude that ignoring clustering can lead to incorrect inferences. The BHMs that they present offer a flexible modeling framework that can be applied more generally to CEA that use CRTs...- Improving costing methods in multicentre economic evaluation: the use of multiple imputation for unit costsRichard Grieve
Health Services Research Unit, London School of Hygiene and Tropical Medicine, Cambridge, UK
Health Econ 19:939-54. 2010.... - SF-6D versus EQ-5D: reasons for differences in utility scores and impact on reported cost-utilityRichard Grieve
London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
Eur J Health Econ 10:15-23. 2009..Further studies are required that examine the impact of the choice of instrument on cost-utility... - Multilevel models for estimating incremental net benefits in multinational studiesRichard Grieve
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK
Health Econ 16:815-26. 2007..We conclude that the validity of assumptions underlying MLMs used in CEA need to be critically evaluated before reliable conclusions can be drawn... - Verteporfin photodynamic therapy cohort study: report 3: cost effectiveness and lessons for future evaluationsRichard Grieve
The London School of Hygiene and Tropical Medicine, London, England
Ophthalmology 116:2471-77.e1-2. 2009.... - Cost effectiveness of interferon alpha or peginterferon alpha with ribavirin for histologically mild chronic hepatitis CR Grieve
Health Services Research Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
Gut 55:1332-8. 2006..For patients with mild chronic hepatitis C the cost effectiveness of antiviral therapy is unknown... - The development and use of a method to compare the costs of acute stroke across EuropeR Grieve
Department of Public Health Sciences, Guy s, King s and St Thomas School of Medicine, London, UK
Age Ageing 30:67-72. 2001..there is a need for more information on the costs of different ways of managing stroke. Methods to compare the costs of stroke care in different countries have not been previously developed... - Using multilevel models for assessing the variability of multinational resource use and cost dataRichard Grieve
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK
Health Econ 14:185-96. 2005..We conclude that using OLS models for assessing international variation can lead to incorrect inferences, and that MLMs are more appropriate for assessing why resource use and costs vary across centres... - Selecting methods for the prediction of future events in cost-effectiveness models: a decision-framework and example from the cardiovascular fieldRichard Grieve
Health Services Research Unit, Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
Health Policy 64:311-24. 2003..Such transparency can help decision-makers understand the scientific basis underpinning models, and therefore make these models more acceptable and useful for health policy-making... - A comparison of the costs and survival of hospital-admitted stroke patients across EuropeR Grieve
Department of Public Health Sciences, GKT School of Medicine, London, UK
Stroke 32:1684-91. 2001..Policy makers require evidence on the costs and outcomes of different ways of organizing stroke care. This study compared the costs and survival of different ways of providing stroke care... - Economic evaluation for hepatitis CR Grieve
Health Services Research Unit, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, United Kingdom
Acta Gastroenterol Belg 65:104-9. 2002..These data will be used to improve the projections of the model. In general, economic evaluations can provide information to help decide where priorities lie both in HCV, and other disease areas... - Comparison of hypertonic saline and alternate-day or daily recombinant human deoxyribonuclease in children with cystic fibrosis: a randomised trialR Suri
Respiratory Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK
Lancet 358:1316-21. 2001..Hypertonic saline improved lung function to the same degree as rhDNase in short-term studies. We compared the effectiveness of daily rhDNase, hypertonic saline, and alternate-day rhDNase in children with cystic fibrosis... - Health benefits of antiviral therapy for mild chronic hepatitis C: randomised controlled trial and economic evaluationM Wright
Department of Medicine, St Mary's Hospital, London, UK
Health Technol Assess 10:1-113, iii. 2006..Liver biopsy before treatment no longer appears justified apart from for older patients (aged 65 or over) with genotype 1. However, further research should monitor the impact this strategy would have on costs and outcomes... - A comparative study of hypertonic saline, daily and alternate-day rhDNase in children with cystic fibrosisR Suri
Respiratory Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK
Health Technol Assess 6:iii, 1-60. 2002 - Older stroke patients in Europe: stroke care and determinants of outcomeA Bhalla
Department of Public Health Sciences, GKT School of Medicine, London, UK
Age Ageing 33:618-24. 2004..in order to implement cost-effective stroke services for older patients, it is necessary to identify how stroke care is currently provided for these patients and how provision relates to outcome... - Verteporfin photodynamic therapy cohort study: report 2: clinical measures of vision and health-related quality of lifeBarnaby C Reeves
The London School of Hygiene and Tropical Medicine, London, England
Ophthalmology 116:2463-70. 2009.... - Verteporfin photodynamic therapy for neovascular age-related macular degeneration: cohort study for the UKB C Reeves
London School of Hygiene and Tropical Medicine, London, UK
Health Technol Assess 16:i-xii, 1-200. 2012..b) is 'outcome' the same in the nhs as in randomised trials?; (c) is 'outcome' the same for patients ineligible for randomised trials?; (d) is VPDT safe when provided in the NHS?; and (e) how effective and cost-effective is VPDT?.. - Pathways of care and resource utilization in a national cohort of patients with transfusion-acquired hepatitis CL Brant
Health Protection Agency, Communicable Disease Surveillance Centre, London, UK
J Viral Hepat 12:618-26. 2005.... - Cost effectiveness analysis of a randomised trial of acupuncture for chronic headache in primary careDavid Wonderling
Health Services Research Unit, London School of Hygiene and Tropical Medicine, London WC1E 7HT
BMJ 328:747. 2004..To evaluate the cost effectiveness of acupuncture in the management of chronic headache... - Evaluation of modernisation of adult critical care services in England: time series and cost effectiveness analysisAndrew Hutchings
Health Services Research Unit, London School of Hygiene and Tropical Medicine, London WC1E 7HT
BMJ 339:b4353. 2009..To evaluate the impact and cost effectiveness of a programme to transform adult critical care throughout England initiated in late 2000... - Stroke in the young: access to care and outcome; a Western versus eastern European perspectiveAjay Bhalla
Division of Health and Social Care Research, King s College, London, United Kingdom
J Stroke Cerebrovasc Dis 17:360-5. 2008..The aims of this study were to describe the provision of stroke care and the factors associated with 3-month mortality and disability (Barthel Index 0-14) in patients younger than 55 years across Western and Eastern Europe... - Evaluating health care programs by combining cost with quality of life measures: a case study comparing capitation and fee for serviceRichard Grieve
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E7HT, UK
Health Serv Res 43:1204-22. 2008..To demonstrate cost-effectiveness analysis (CEA) for evaluating different reimbursement models... - Addressing the issues that arise in analysing multicentre cost data, with application to a multinational studySimon G Thompson
MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
J Health Econ 25:1015-28. 2006..Analysis of multinational cost data must recognise differences in mean, spread and skewness across centres, as well as the data's hierarchical structure... - The Immediate Management of the Patient with Rupture: Open Versus Endovascular repair (IMPROVE) aneurysm trial--ISRCTN 48334791 IMPROVE trialistsJ T Powell
Imperial College, Charing Cross, London, UK
Acta Chir Belg 109:678-80. 2009..Systematic reviews have suggested a survival advantage for patients with ruptured abdominal aortic aneurysm (AAA), who are managed by endovascular repair. These reviews are based on single centre experiences of selected patients... - Neonatal ventilation with inhaled nitric oxide vs. ventilatory support without inhaled nitric oxide for infants with severe respiratory failure born at or near term: the INNOVO multicentre randomised controlled trialD Field
Department of Health Science, University of Leicester, London, UK
Neonatology 91:73-82. 2007..Evidence from European centres to support the use of nitric oxide (NO) in mature newborns with evidence of severe respiratory failure is sparse... - Respiratory function during infancy in survivors of the INNOVO trialAh Fong Hoo
Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health, London, UK
Pediatr Pulmonol 44:155-61. 2009..Furthermore, results were compared to lung function of healthy infants... - Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trialPaul Ellis
Guy s and St Thomas NHS Trust, London, UK
Lancet 373:1681-92. 2009..The UK TACT study (CRUK01/001) investigated whether sequential docetaxel after anthracycline chemotherapy would improve patient outcome compared with standard chemotherapy of similar duration...