Alison Grant

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. pmc Isoniazid preventive therapy and risk for resistant tuberculosis
    Maria Elvira Balcells
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
    Emerg Infect Dis 12:744-51. 2006
  2. pmc "That is why I stopped the ART": patients' & providers' perspectives on barriers to and enablers of HIV treatment adherence in a South African workplace programme
    Mison Dahab
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    BMC Public Health 8:63. 2008
  3. pmc Low haemoglobin predicts early mortality among adults starting antiretroviral therapy in an HIV care programme in South Africa: a cohort study
    Elizabeth C Russell
    London School of Hygiene and Tropical Medicine, London, UK
    BMC Public Health 10:433. 2010
  4. pmc Contrasting predictors of poor antiretroviral therapy outcomes in two South African HIV programmes: a cohort study
    Mison Dahab
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    BMC Public Health 10:430. 2010
  5. pmc Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa: a cohort study
    Katherine L Fielding
    London School of Hygiene and Tropical Medicine, London, UK
    BMC Infect Dis 8:93. 2008
  6. doi request reprint Adverse events with isoniazid preventive therapy: experience from a large trial
    Alison D Grant
    Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    AIDS 24:S29-36. 2010
  7. ncbi request reprint Clinical features of HIV disease in developing countries
    A Grant
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Lepr Rev 73:197-205. 2002
  8. doi request reprint 'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy
    Alison D Grant
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK
    AIDS 24:S37-44. 2010
  9. doi request reprint Managing drug resistant tuberculosis
    Alison Grant
    Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London WC1E 6JB
    BMJ 337:a1110. 2008
  10. ncbi request reprint Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-infected men in South Africa: a novel randomized incremental recruitment study
    Alison D Grant
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, England
    JAMA 293:2719-25. 2005

Detail Information

Publications28

  1. pmc Isoniazid preventive therapy and risk for resistant tuberculosis
    Maria Elvira Balcells
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
    Emerg Infect Dis 12:744-51. 2006
    ..The diagnosis of active TB should be excluded before IPT. Continued surveillance for isoniazid resistance is essential...
  2. pmc "That is why I stopped the ART": patients' & providers' perspectives on barriers to and enablers of HIV treatment adherence in a South African workplace programme
    Mison Dahab
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    BMC Public Health 8:63. 2008
    ..This qualitative study examines potential barriers to, and facilitators of, adherence to ART in a workplace programme in South Africa...
  3. pmc Low haemoglobin predicts early mortality among adults starting antiretroviral therapy in an HIV care programme in South Africa: a cohort study
    Elizabeth C Russell
    London School of Hygiene and Tropical Medicine, London, UK
    BMC Public Health 10:433. 2010
    ..We investigated risk factors for mortality among adults starting ART in a multi-clinic community programme in South Africa...
  4. pmc Contrasting predictors of poor antiretroviral therapy outcomes in two South African HIV programmes: a cohort study
    Mison Dahab
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    BMC Public Health 10:430. 2010
    ..To help address this evidence gap, this observational cohort study examined baseline factors potentially predictive of poor treatment outcomes in two ART programmes in South Africa, with a particular focus on determinants of adherence...
  5. pmc Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa: a cohort study
    Katherine L Fielding
    London School of Hygiene and Tropical Medicine, London, UK
    BMC Infect Dis 8:93. 2008
    ..Reasons for the variation in reported treatment outcomes from antiretroviral therapy (ART) programmes in developing countries are not clearly defined...
  6. doi request reprint Adverse events with isoniazid preventive therapy: experience from a large trial
    Alison D Grant
    Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    AIDS 24:S29-36. 2010
    ..We describe isoniazid-related adverse events in Thibela TB, a cluster-randomized study of community-wide isoniazid preventive therapy (IPT) among gold miners in South Africa, where HIV prevalence is estimated at 30%...
  7. ncbi request reprint Clinical features of HIV disease in developing countries
    A Grant
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Lepr Rev 73:197-205. 2002
    ..A high index of suspicion of HIV infection and knowledge of the local spectrum of HIV disease are important for early diagnosis and appropriate management of HIV-related disease...
  8. doi request reprint 'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy
    Alison D Grant
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK
    AIDS 24:S37-44. 2010
    ..To describe a programme of community education and mobilization to promote uptake in a cluster-randomized trial of tuberculosis preventive therapy offered to all members of intervention clusters...
  9. doi request reprint Managing drug resistant tuberculosis
    Alison Grant
    Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London WC1E 6JB
    BMJ 337:a1110. 2008
  10. ncbi request reprint Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-infected men in South Africa: a novel randomized incremental recruitment study
    Alison D Grant
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, England
    JAMA 293:2719-25. 2005
    ....
  11. doi request reprint Tuberculosis among people with HIV infection in the United Kingdom: opportunities for prevention?
    Alison D Grant
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    AIDS 23:2507-15. 2009
    ..To investigate the incidence of, and risk factors for, tuberculosis among HIV clinic attendees in the United Kingdom...
  12. ncbi request reprint The spectrum of HIV-related disease in rural Central Thailand
    Donald Inverarity
    London School of Hygiene and Tropical Medicine, London, England
    Southeast Asian J Trop Med Public Health 33:822-31. 2002
    ..Community care and palliative care services for HIV-infected individuals will increasingly be required in this region...
  13. doi request reprint Common inherited mitochondrial DNA mutations and nucleoside reverse transcriptase inhibitor-induced severe hyperlactataemia in HIV-infected adults: an exploratory study
    Alejandro Arenas-Pinto
    Centre for Sexual Health and HIV Research, University College London, London, UK
    Antivir Ther 17:275-82. 2012
    ..Genetic predisposition to dideoxynucleoside-induced mitochondrial dysfunction might be related to mitochondrial DNA (mtDNA) polymorphisms. Severe hyperlactataemia is probably the best model to assess such a predisposition...
  14. pmc Antiretroviral therapy using zidovudine, lamivudine, and efavirenz in South Africa: tolerability and clinical events
    Christopher J Hoffmann
    Aurum Institute for Health Research, Johannesburg, South Africa
    AIDS 22:67-74. 2008
    ..To describe the safety and tolerability of zidovudine, lamivudine, and efavirenz in a low-income setting...
  15. ncbi request reprint Tuberculosis preventive therapy in the era of HIV infection: overview and research priorities
    Gavin J Churchyard
    Aurum Institute for Health Research, Marshalltown, South Africa
    J Infect Dis 196:S52-62. 2007
    ..Ongoing research will help to determine how best to use this intervention in the care of HIV-infected persons and in the control of TB on a wider basis...
  16. pmc Attitudes to directly observed antiretroviral treatment in a workplace HIV care programme in South Africa
    Liesl S Page-Shipp
    Aragon Consulting, Craighall, South Africa
    Sex Transm Infect 83:383-6. 2007
    ..To investigate attitudes to directly observed antiretroviral therapy (DOT ART) among HIV infected adults attending a workplace HIV care programme in South Africa...
  17. ncbi request reprint Hepatotoxicity in an African antiretroviral therapy cohort: the effect of tuberculosis and hepatitis B
    Christopher J Hoffmann
    Aurum Institute for Health Research, Johannesburg, South Africa
    AIDS 21:1301-8. 2007
    ..Hepatotoxicity is a significant complication of antiretroviral therapy (ART). We assessed the incidence of and risk factors for hepatotoxicity among HIV-infected individuals on ART in South Africa...
  18. ncbi request reprint HIV/AIDS treatment and HIV vaccines for Africa
    Paul J Weidle
    Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Lancet 359:2261-7. 2002
    ..In this review, we discuss the prospects for use of treatment and vaccines in resource-poor settings...
  19. ncbi request reprint Efficacy of secondary isoniazid preventive therapy among HIV-infected Southern Africans: time to change policy?
    Gavin J Churchyard
    Aurum Health Research, Welkom, South Africa
    AIDS 17:2063-70. 2003
    ..To determine the efficacy of secondary preventive therapy against tuberculosis (TB) among gold miners working in South Africa...
  20. ncbi request reprint Human immunodeficiency virus and the prevalence of undiagnosed tuberculosis in African gold miners
    Elizabeth L Corbett
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
    Am J Respir Crit Care Med 170:673-9. 2004
    ..The difference in mean duration of smear positivity was particularly marked and, if generalizable, will have major implications for TB control prospects in high HIV prevalence areas...
  21. pmc The natural history of HIV-1 and HIV-2 infections in adults in Africa: a literature review
    Shabbar Jaffar
    Medical Research Council Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
    Bull World Health Organ 82:462-9. 2004
    ..Prophylactic regimens and better treatments could have some effect on survival, but major improvements in life expectancy will require HAART...
  22. ncbi request reprint Does tuberculosis increase HIV load?
    John H Day
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 190:1677-84. 2004
    ..The effect that tuberculosis (TB) has on human immunodeficiency virus (HIV) disease progression is not clearly understood...
  23. ncbi request reprint Morbidity and mortality in South African gold miners: impact of untreated disease due to human immunodeficiency virus
    Elizabeth L Corbett
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Clin Infect Dis 34:1251-8. 2002
    ..A broad range of infectious conditions is significantly associated with HIV infection in South African miners. Identification and implementation of effective prophylactic regimens are urgently needed...
  24. ncbi request reprint Malaria in camps for internally-displaced persons in Uganda: evaluation of an insecticide-treated bednet distribution programme
    Sebastian Spencer
    Medecins Sans Frontieres, 4 rue Saint Sabin, 75011 Paris, France
    Trans R Soc Trop Med Hyg 98:719-27. 2004
    ..63, 95% CI 0.46-0.87); ITNs with severe damage remained effective (RR for severely damaged net 0.58, 95% CI 0.35-0.98). There was no significant difference in haemoglobin concentration between ITN users and non-users...
  25. ncbi request reprint Early risk assessment for viral haemorrhagic fever: experience at the Hospital for Tropical Diseases, London, UK
    Charles J Woodrow
    The Hospital for Tropical Diseases, Directorate of Infection, University College London Hospitals, Mortimer Market, Capper Street off Tottenham Court Road, London WC1E 6AU, UK
    J Infect 54:6-11. 2007
    ..To implement a policy of systematic screening for viral haemorrhagic fever (VHF) among travellers returning from African countries with fever, commencing at initial clinical contact...
  26. pmc Undiagnosed tuberculosis in a community with high HIV prevalence: implications for tuberculosis control
    Robin Wood
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Health Science Faculty, UCT Observatory, Cape Town 7925, South Africa
    Am J Respir Crit Care Med 175:87-93. 2007
    ..We conducted a cross-sectional survey of pulmonary TB (PTB) and HIV infection in a community of 13,000 with high HIV prevalence and high TB notification rate and a well-functioning DOTS TB control program...
  27. pmc Early predictors of mortality from Pneumocystis jirovecii pneumonia in HIV-infected patients: 1985-2006
    Peter D Walzer
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, University College London, London, United Kingdom
    Clin Infect Dis 46:625-33. 2008
    ..Previous studies of PCP that identified case-fatality risk factors involved small numbers of patients, were performed over few years, and often focused on patients who were admitted to the intensive care unit...
  28. ncbi request reprint Use of traditional medicine by HIV-infected individuals in South Africa in the era of antiretroviral therapy
    Dale A Babb
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Psychol Health Med 12:314-20. 2007
    ..Concomitant use with ART has the potential for drug interactions and should be discussed routinely in ART counselling. Further work is warranted to investigate whether commonly used traditional medicines interact with ART in vivo...