Research Topics
| Phil EdwardsSummaryAffiliation: London School of Hygiene and Tropical Medicine Country: UK Publications
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Detail Information
Publications
The MRC CRASH Trial: study design, baseline data, and outcome in 1000 randomised patients in the pilot phaseP Edwards
CRASH Trial Coordinating Centre, London School of Hygiene and Tropical Medicine, London, UK
Emerg Med J 19:510-4. 2002..To assess whether large numbers of patients could be enrolled and treated within eight hours from injury and then followed up at six months...
The added value of ordinal analysis in clinical trials: an example in traumatic brain injuryBob Roozenbeek
Department of Neurosurgery, Antwerp University Hospital, Wilrijkstraat 10, Edegem, Belgium
Crit Care 15:R127. 2011..The objective of this study is to quantify the benefits of ordinal analysis in the real-life situation of a large TBI trial...
Deaths of cyclists in London: trends from 1992 to 2006Andrei S Morgan
Department of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
BMC Public Health 10:699. 2010..We sought to replicate the previous work using data on cyclist deaths in London between 1992 and 2006, specifically investigating whether heavy goods vehicles continued to pose a threat...
Meta-analysis of randomised trials of monetary incentives and response to mailed questionnairesPhil Edwards
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
J Epidemiol Community Health 59:987-99. 2005..To quantify the increase in mailed questionnaire response attributable to a monetary incentive...
Deaths from injury in children and employment status in family: analysis of trends in class specific death ratesPhil Edwards
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT
BMJ 333:119. 2006..To examine socioeconomic inequalities in rates of death from injury in children in England and Wales...
Population adiposity and climate changePhil Edwards
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
Int J Epidemiol 38:1137-40. 2009..We estimate the impact on greenhouse gas emissions of increases in the population distribution of body mass index (BMI)...
Young men were at risk of becoming lost to follow-up in a cohort of head-injured adultsPhil Edwards
CRASH trials Co ordinating Centre, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
J Clin Epidemiol 60:417-24. 2007..This study is to identify predictors of loss to follow-up among adults with head injury...
Serious injuries in children: variation by area deprivation and settlement typeP Edwards
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
Arch Dis Child 93:485-9. 2008..To examine the variation in serious injuries in children by the level of deprivation in an area and by types of settlement...
Assessing the effectiveness and cost effectiveness of adaptive e-Learning to improve dietary behaviour: protocol for a systematic reviewPhil Edwards
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
BMC Public Health 10:200. 2010..The aims of this systematic review are to determine the effectiveness and cost-effectiveness of adaptive e-Learning for improving dietary behaviours...
Questionnaires in clinical trials: guidelines for optimal design and administrationPhil Edwards
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
Trials 11:2. 2010..Theory-based guidelines for style, appearance, and layout of self-administered questionnaires have been proposed but require evaluation...
Scald risk in social housing can be reduced through thermostatic control system without increasing Legionella risk: a cluster randomised trialP Edwards
NPHIR, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Arch Dis Child 96:1097-102. 2011..To quantify the effects of a thermostatic control system in social (public) housing on the prevalence of dangerous (>60°C) water temperatures and on fuel consumption...
Identification of randomized controlled trials in systematic reviews: accuracy and reliability of screening recordsPhil Edwards
Public Health Intervention Research Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, 49 51 Bedford Square, London WC1B 3DP, UK
Stat Med 21:1635-40. 2002..Two reviewers should screen records for eligibility, whenever possible, in order to maximize ascertainment of relevant trials...
Increasing response rates to postal questionnaires: systematic reviewPhil Edwards
CRASH Trial Co ordinating Centre, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1B 1DP
BMJ 324:1183. 2002..To identify methods to increase response to postal questionnaires...
Follow-up by mail in clinical trials: does questionnaire length matter?Phil Edwards
CRASH Trial Co ordinating Centre, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, 49 51 Bedford Square London, WC1B 3DP, UK
Control Clin Trials 25:31-52. 2004..If a new follow-up questionnaire is to be designed, it should be made as short as possible without compromising the data collection requirements of the trial...
An economic evaluation of adaptive e-learning devices to promote weight loss via dietary change for people with obesityAlec Miners
Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
BMC Health Serv Res 12:190. 2012..The aim of this study is to assess the cost-effectiveness of e-learning devices as a method of promoting weight loss via dietary change...
Patient outcome after traumatic brain injury in high-, middle- and low-income countries: analysis of data on 8927 patients in 46 countriesMary J De Silva
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK
Int J Epidemiol 38:452-8. 2009..Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide. The burden of TBI is greatest in low- and middle-income countries (LAMIC), yet little is known about patient outcomes in these settings...
Effect of 20 mph traffic speed zones on road injuries in London, 1986-2006: controlled interrupted time series analysisChris Grundy
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London WC1E 7HT
BMJ 339:b4469. 2009..To quantify the effect of the introduction of 20 mph (32 km an hour) traffic speed zones on road collisions, injuries, and fatalities in London...
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trialIan Roberts
Clinical Trials Unit, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
Lancet 377:1096-101, 1101.e1-2. 2011..Tranexamic acid significantly reduced all-cause mortality. Because tranexamic acid is thought to exert its effect through inhibition of fibrinolysis, we undertook exploratory analyses of its effect on death due to bleeding...
The effectiveness of mobile-health technologies to improve health care service delivery processes: a systematic review and meta-analysisCaroline Free
Clinical Trials Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS Med 10:e1001363. 2013..Mobile health interventions could have beneficial effects on health care delivery processes. We aimed to conduct a systematic review of controlled trials of mobile technology interventions to improve health care delivery processes...
Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trialKatharine Ker
Clinical Trials Unit, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
BMC Emerg Med 12:3. 2012..Based on data from the CRASH-2 trial, global mortality data and a systematic literature review, we estimated the number of premature deaths that might be averted every year worldwide through the use of TXA...
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysisKatharine Ker
Clinical Trials Unit, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
BMJ 344:e3054. 2012..To assess the effect of tranexamic acid on blood transfusion, thromboembolic events, and mortality in surgical patients...
Covariate adjustment increased power in randomized controlled trials: an example in traumatic brain injuryElizabeth L Turner
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
J Clin Epidemiol 65:474-81. 2012..We aimed to determine to what extent covariate adjustment could affect power in a randomized controlled trial (RCT) of a heterogeneous population with traumatic brain injury (TBI)...
The impact of 20 mph traffic speed zones on inequalities in road casualties in LondonRebecca Steinbach
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
J Epidemiol Community Health 65:921-6. 2011..This study quantified the current and potential future impact of the introduction of 20 mph zones on socioeconomic inequalities in road casualties in London...
Walking, cycling and transport safety: an analysis of child road deathsBeth Sonkin
London School of Hygiene and Tropical Medicine, UK
J R Soc Med 99:402-5. 2006..This might encourage more walking and cycling and also has the potential to reduce social class gradients in injury mortality...
Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injuryPablo Perel
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
BMC Med Res Methodol 8:72. 2008..The objectives of this study were to evaluate the association and predictive validity between a simple disability scale at hospital discharge, the Oxford Handicap Scale (OHS), and the GOS at 6 months among TBI patients...
Public health benefits of strategies to reduce greenhouse-gas emissions: urban land transportJames Woodcock
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
Lancet 374:1930-43. 2009....
Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trialCaroline Free
Clinical Trials Research Unit, London School of Hygiene and Tropical Medicine, UK
Lancet 378:49-55. 2011..We assessed the effect of an automated smoking cessation programme delivered via mobile phone text messaging on continuous abstinence, which was biochemically verified at 6 months...
'Race' or place? Explaining ethnic variations in childhood pedestrian injury rates in LondonRebecca Steinbach
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom
Health Place 16:34-42. 2010..Ethnic differences in injury rates cannot be explained by minority ethnic status or area deprivation, but are likely to result from the complex ways in which ethnicity shapes local experiences of exposure to injury risk...
Does the decline in road traffic injury in London vary by ethnicity?N Malhotra
London Health Observatory, London, UK
Inj Prev 14:333-7. 2008..To examine ethnic variations in trends in road traffic injuries in London...
Perceptions of tap water temperatures, scald risk and prevention among parents and older people in social housing: a qualitative studyMary Alison Durand
Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, 15 17 Tavistock Place, London WC1H 9SH, UK
Burns 38:585-90. 2012..Evidence suggests that reducing tap water temperatures in social (public) housing through 'passive' means is effective in reducing risk. However, little is known about parents' or older people's perceptions of scald risk and prevention...
Cycling and the city: a case study of how gendered, ethnic and class identities can shape healthy transport choicesRebecca Steinbach
London School of Hygiene and Tropical Medicine, Public Health and Policy, Keppel Street, London WC1E 7HT, United Kingdom
Soc Sci Med 72:1123-30. 2011..While the identities of some professional (largely White) men and women could be bolstered by cycling, the aesthetic and symbolic goals of cycling were less appealing to those with other class, gendered and ethnic identities...
Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patientsPablo Perel
London School of Hygiene and Tropical Medicine, London WC1B 3DP
BMJ 336:425-9. 2008..To develop and validate practical prognostic models for death at 14 days and for death or severe disability six months after traumatic brain injury...
No socioeconomic inequalities in colorectal cancer survival within a randomised clinical trialU Nur
Cancer Research UK Cancer Survival Group, Non communicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
Br J Cancer 99:1923-8. 2008....
Flying bullets and speeding cars: analysis of child injury deaths in the Palestinian TerritoryA Shaheen
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
East Mediterr Health J 14:406-14. 2008..6). In comparison, transport accidents were the leading cause of death in children in both Israel (5.0) and England and Wales (3.5)...
Traffic and the risk of vehicle-related pedestrian injury: a decision analytic support toolZ Chalabi
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Inj Prev 14:196-201. 2008..However, mathematical modeling can help to establish the injury consequences of transport policy decisions...
Car manufacturers and global road safety: a word frequency analysis of road safety documentsI Roberts
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
Inj Prev 12:320-2. 2006..However, some commentators are sceptical. The authors examined road safety policy documents to assess the extent of any bias...
The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic reviewCaroline Free
Clinical Trials Unit, London School of Hygiene and Tropical Medicine, London, UK
PLoS Med 10:e1001362. 2013..We conducted a systematic review to assess the effectiveness of mobile technology interventions delivered to health care consumers...
Personally addressed hand-signed letters increase questionnaire response: a meta-analysis of randomised controlled trialsPippa Scott
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
BMC Health Serv Res 6:111. 2006..We sought to quantify the effect on response when researchers address participants personally by name on letters that accompany questionnaires...
Systematic review of prognostic models in traumatic brain injuryPablo Perel
Nutrition and Public Health Intervention Research Unit, Epidemiology and Population Health Department, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
BMC Med Inform Decis Mak 6:38. 2006..Two reviewers independently examined titles, abstracts and assessed whether each met the pre-defined inclusion criteria...
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trialHaleema Shakur
Clinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Lancet 376:23-32. 2010..We assessed the effects of early administration of a short course of tranexamic acid on death, vascular occlusive events, and the receipt of blood transfusion in trauma patients...
Energy and transportJames Woodcock
London School of Hygiene and Tropical Medicine, London, UK
Lancet 370:1078-88. 2007..There exists the potential for a global contraction and convergence in use of fossil-fuel energy for transport to benefit health and achieve sustainability...
Misadventures to patients during surgical and medical care in England and Wales: an analysis of deaths and hospital episodesKatharine Ker
Department of Nutrition and Public Health Intervention Research, London School of Hygiene and Tropical Medicine, UK
J R Soc Med 104:292-8. 2011..Older patients appear to be at higher risk of experiencing and dying from misadventure. Interpretation of recent trends is limited by uncertainties regarding the consistency and coverage of coding...
Women in an infertility survey responded more by mail but preferred a choice: randomized controlled trialMelanie Morris
Department of Non communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
J Clin Epidemiol 66:226-35. 2013..To evaluate three modes of questionnaire completion (online, mail, and telephone) and a choice group for a questionnaire survey with a sensitive topic...
Physical activity and depressive symptoms in adolescents: a prospective studyCatherine Rothon
Centre for Psychiatry, Queen Mary University of London, Barts and the London School of Medicine and Dentistry, Wolfson Institute of Preventive Medicine, Charterhouse Square, London, UK
BMC Med 8:32. 2010..There is a particular lack of evidence from longitudinal studies. This study examines the relationship between depression and physical activity using the Research with East London Adolescents: Community Health Survey (RELACHS)...
Families bereaved by road traffic crashes: linkage of mortality records with 1971-2001 censusesR Sullivan
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
Inj Prev 15:364-8. 2009..To estimate the number of people alive in England & Wales who have lost a close family member in a fatal road traffic crash...
Why the government was right to change the 'Our Healthier Nation' accidental injury targetP C Cryer
South East Institute of Public Health, United Medical and Dental School of Guy s and St Thomas Hospitals, London, UK
Public Health 114:232-7. 2000....
Urban residential fire and flame injuries: a population based studyC DiGuiseppi
Department of Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, UK
Inj Prev 6:250-4. 2000..Fires are a leading cause of death, but non-fatal injuries from residential fires have not been well characterised...
Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trialIan Roberts
Lancet 364:1321-8. 2004..22) or time since injury (p=0.05). INTERPRETATION: Our results show there is no reduction in mortality with methylprednisolone in the 2 weeks after head injury. The cause of the rise in risk of death within 2 weeks is unclear...
Incidence of fires and related injuries after giving out free smoke alarms: cluster randomised controlled trialCarolyn DiGuiseppi
Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Campus Box B 119, Denver, CO 80262, USA
BMJ 325:995. 2002..To measure the effect of giving out free smoke alarms on rates of fires and rates of fire related injury in a deprived multiethnic urban population...
Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 monthsPhil Edwards
Lancet 365:1957-9. 2005..These results lend support to our earlier conclusion that corticosteroids should not be used routinely in the treatment of head injury...
Trauma care research and the war on uncertaintyIan Roberts
BMJ 331:1094-6. 2005
A retrospective case-control study of developmental and other outcomes in a cohort of Australian children conceived by intracytoplasmic sperm injection compared with a similar group in the United KingdomAlastair G Sutcliffe
Department of Child Health Royal Free and University College Medical School, London, United Kingdom
Fertil Steril 79:512-6. 2003..To investigate the possibility that children born after ICSI were at increased risk for neurodevelopmental delay...
Mailed questionnaires: length mattersPhil Edwards
J Public Health (Oxf) 26:214; author reply 214-5. 2004
Transport policy is food policyPhil Edwards
Lancet 371:1661. 2008
Prognosis following head injury: a survey of doctors from developing and developed countriesPablo Perel
J Eval Clin Pract 13:464-5. 2007
