S Brooker

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. ncbi request reprint Schistosomiasis control
    Simon Brooker
    Lancet 363:658-9. 2004
  2. ncbi request reprint Synergistic associations between hookworm and other helminth species in a rural community in Brazil
    Fiona M Fleming
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    Trop Med Int Health 11:56-64. 2006
  3. pmc Bayesian geostatistical prediction of the intensity of infection with Schistosoma mansoni in East Africa
    A C A Clements
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Parasitology 133:711-9. 2006
  4. pmc Challenges for consent and community engagement in the conduct of cluster randomized trial among school children in low income settings: experiences from Kenya
    George Okello
    Health Systems Department, Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Kilifi, Kenya
    Trials 14:142. 2013
  5. pmc Monitoring and evaluating the impact of national school-based deworming in Kenya: study design and baseline results
    Charles S Mwandawiro
    Eastern and Southern Africa Centre of International Parasite Control ESACIPAC, Kenya Medical Research Institute KEMRI, Nairobi, Kenya
    Parasit Vectors 6:198. 2013
  6. pmc Local perceptions of intermittent screening and treatment for malaria in school children on the south coast of Kenya
    George Okello
    Social and Behavioural Research Group, Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Kilifi, Kenya
    Malar J 11:185. 2012
  7. pmc Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa
    Simon J Brooker
    Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
    J Infect Dis 205:841-52. 2012
  8. pmc Cost analysis of school-based intermittent screening and treatment of malaria in Kenya
    Thomas L Drake
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 10:273. 2011
  9. pmc Costs and cost-effectiveness of delivering intermittent preventive treatment through schools in western Kenya
    Matilda Temperley
    London School of Hygiene and Tropical Medicine, London, UK
    Malar J 7:196. 2008
  10. pmc Hookworm-related anaemia among pregnant women: a systematic review
    Simon Brooker
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Negl Trop Dis 2:e291. 2008

Collaborators

Detail Information

Publications82

  1. ncbi request reprint Schistosomiasis control
    Simon Brooker
    Lancet 363:658-9. 2004
  2. ncbi request reprint Synergistic associations between hookworm and other helminth species in a rural community in Brazil
    Fiona M Fleming
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    Trop Med Int Health 11:56-64. 2006
    ..To identify possible synergistic associations of hookworm and other helminths...
  3. pmc Bayesian geostatistical prediction of the intensity of infection with Schistosoma mansoni in East Africa
    A C A Clements
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Parasitology 133:711-9. 2006
    ..Such a map has important implications for schisosomiasis control programmes in the region...
  4. pmc Challenges for consent and community engagement in the conduct of cluster randomized trial among school children in low income settings: experiences from Kenya
    George Okello
    Health Systems Department, Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Kilifi, Kenya
    Trials 14:142. 2013
    ..In this paper we discuss our experiences of consent, assent and community engagement in implementing a large school-based cluster randomized trial in rural Kenya...
  5. pmc Monitoring and evaluating the impact of national school-based deworming in Kenya: study design and baseline results
    Charles S Mwandawiro
    Eastern and Southern Africa Centre of International Parasite Control ESACIPAC, Kenya Medical Research Institute KEMRI, Nairobi, Kenya
    Parasit Vectors 6:198. 2013
    ..The article describes the M&E design of the Kenya national SBD programme and presents results from the baseline survey conducted in early 2012...
  6. pmc Local perceptions of intermittent screening and treatment for malaria in school children on the south coast of Kenya
    George Okello
    Social and Behavioural Research Group, Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Kilifi, Kenya
    Malar J 11:185. 2012
    ..This study was conducted alongside a cluster-randomized trial to investigate local perceptions of school-based IST among parents and other stakeholders on the Kenyan south coast...
  7. pmc Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa
    Simon J Brooker
    Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
    J Infect Dis 205:841-52. 2012
    ..This study investigates the distribution and heterogeneity of coinfection with Plasmodium falciparum and 3 major helminth species across East Africa...
  8. pmc Cost analysis of school-based intermittent screening and treatment of malaria in Kenya
    Thomas L Drake
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 10:273. 2011
    ..This paper analyses the costs of intermittent screening and treatment (IST) of malaria in schools, implemented as part of a cluster-randomized controlled trial on the Kenyan coast...
  9. pmc Costs and cost-effectiveness of delivering intermittent preventive treatment through schools in western Kenya
    Matilda Temperley
    London School of Hygiene and Tropical Medicine, London, UK
    Malar J 7:196. 2008
    ..This paper evaluates the costs and cost-effectiveness of intermittent preventive treatment (IPT) as delivered by teachers in schools in western Kenya...
  10. pmc Hookworm-related anaemia among pregnant women: a systematic review
    Simon Brooker
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Negl Trop Dis 2:e291. 2008
    ..We sought to review existing evidence on the role of hookworm as a risk factor for anaemia among pregnant women. We also estimate the number of hookworm infections in pregnant women in sub-Saharan Africa (SSA)...
  11. pmc Rapid assessment of Schistosoma mansoni: the validity, applicability and cost-effectiveness of the Lot Quality Assurance Sampling method in Uganda
    Simon Brooker
    London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 10:647-58. 2005
    ..19 per schoolchild. We conclude that, in Uganda, LQAS provides a rapid, valid and cost-effective method for guiding decision makers in allocating finite resources for the control of schistosomiasis...
  12. ncbi request reprint Integrated disease mapping in a polyparasitic world
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom
    Geospat Health 1:141-6. 2007
  13. pmc Modelling heterogeneity and the impact of chemotherapy and vaccination against human hookworm
    L Sabatelli
    London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    J R Soc Interface 5:1329-41. 2008
    ....
  14. pmc Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control
    Simon Brooker
    London School of Hygiene and Tropical Medicine, Kepel Street, London, United Kingdom
    Am J Trop Med Hyg 77:88-98. 2007
    ..We suggest that both school-age children and pregnant women--groups which have the highest risk of anemia--would benefit from an integrated approach to malaria and helminth control...
  15. pmc The co-distribution of Plasmodium falciparum and hookworm among African schoolchildren
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    Malar J 5:99. 2006
    ..This is despite the potential public health importance of co-infection and synergistic opportunities for control...
  16. pmc Malaria in African schoolchildren: options for control
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Trans R Soc Trop Med Hyg 102:304-5. 2008
    ..New approaches to school-based chemoprevention and treatment may also be able to play an important role in school-based malaria control, although these require further investigation...
  17. pmc Cost and cost-effectiveness of nationwide school-based helminth control in Uganda: intra-country variation and effects of scaling-up
    Simon Brooker
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Health Policy Plan 23:24-35. 2008
    ..70-9.51). Independent variables were shown to be statistically associated with both sets of estimates. This study highlights the potential bias in transferring data across settings without understanding the nature of observed variations...
  18. pmc Spatial epidemiology of Plasmodium vivax, Afghanistan
    Simon Brooker
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    Emerg Infect Dis 12:1600-2. 2006
    ..Remote sensing enabled development of a risk map, thereby providing a valuable tool to help guide malaria control strategies...
  19. pmc Contrasting patterns in the small-scale heterogeneity of human helminth infections in urban and rural environments in Brazil
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, WCIE 7HT, UK
    Int J Parasitol 36:1143-51. 2006
    ..We suggest that such species-specific differences in patterns of infection by environment are primarily due to variation in exposure and parasite life cycle, although host genetic factors cannot be ruled out...
  20. ncbi request reprint Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 101:146-54. 2007
    ..Our results indicate that, even in areas where there is a low overall prevalence of anaemia, hookworm can still have an important impact on host iron status, especially in school-aged children and the elderly...
  21. pmc Spatial epidemiology of human schistosomiasis in Africa: risk models, transmission dynamics and control
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Trans R Soc Trop Med Hyg 101:1-8. 2007
    ..It is suggested that improved incorporation of transmission dynamics into spatial models and assessment of uncertainties inherent in data and modelling approaches represent important future research directions...
  22. pmc Spatial heterogeneity of parasite co-infection: Determinants and geostatistical prediction at regional scales
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Int J Parasitol 39:591-7. 2009
    ....
  23. pmc Spatial analysis of the distribution of intestinal nematode infections in Uganda
    S Brooker
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Epidemiol Infect 132:1065-71. 2004
    ..The implications of the results are discussed in relation to parasite spatial epidemiology and the prediction of infection distributions...
  24. ncbi request reprint Mapping soil-transmitted helminths in Southeast Asia and implications for parasite control
    S Brooker
    Disease Control and Vector Biology Unit, London School of Hygiene and Tropical Medicine, London, UK
    Southeast Asian J Trop Med Public Health 34:24-36. 2003
    ..These applications of GIS and remote sensing provide a good basis for developing control of soil-transmitted helminths in the region...
  25. pmc Improving educational achievement and anaemia of school children: design of a cluster randomised trial of school-based malaria prevention and enhanced literacy instruction in Kenya
    Simon Brooker
    Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
    Trials 11:93. 2010
    ..This study aims to evaluate the impact of school-based malaria prevention and enhanced literacy instruction on the health and educational achievement of school children in Kenya...
  26. pmc Estimating the global distribution and disease burden of intestinal nematode infections: adding up the numbers--a review
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
    Int J Parasitol 40:1137-44. 2010
    ..Particular attention is paid to efforts to improve our ability to define at-risk populations, based on a Global Atlas of Helminth Infection, and to better estimate attributable morbidity...
  27. pmc The use of schools for malaria surveillance and programme evaluation in Africa
    Simon Brooker
    Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
    Malar J 8:231. 2009
    ..Finally, areas requiring further investigation are highlighted...
  28. ncbi request reprint Spatial clustering of malaria and associated risk factors during an epidemic in a highland area of western Kenya
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 9:757-66. 2004
    ..Conditional multiple logistic regression analysis showed that the risk of malaria was higher in children who were underweight, who lived at lower altitudes, and who lived in households where drugs were not kept at home...
  29. pmc An updated atlas of human helminth infections: the example of East Africa
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    Int J Health Geogr 8:42. 2009
    ..In an attempt to address the paucity of geographical information on helminth risk, this article describes the development of an updated global atlas of human helminth infection, showing the example of East Africa...
  30. ncbi request reprint Evaluating the epidemiological impact of national control programmes for helminths
    Simon Brooker
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK
    Trends Parasitol 20:537-45. 2004
    ..Using the example of schistosomiasis, this article outlines a framework for the evaluation of the impact of national control programmes, highlighting the important epidemiological and practical issues that must be addressed...
  31. pmc Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa
    S Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom
    Parasitology 136:1707-18. 2009
    ..The lessons from the mapping of human helminth infections may also be relevant for the rapid mapping of malaria as its control efforts are intensified...
  32. ncbi request reprint Epidemiology of helminth infections and their relationship to clinical malaria in southwest Uganda
    Adrienne E Shapiro
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 99:18-24. 2005
    ..The association between helminth infection and clinical malaria was investigated in two villages and no evidence for an association was observed between the presence of infection or heavy infection and risk of malaria...
  33. pmc Predicting the distribution of urinary schistosomiasis in Tanzania using satellite sensor data
    S Brooker
    Department of Infectious Disease Epidemiology, Imperial College School of Medicine, London, UK
    Trop Med Int Health 6:998-1007. 2001
    ..The developed model was then used to provide estimates of the number of schoolchildren at risk of high prevalence and associated programme costs...
  34. pmc Bayesian spatial analysis and disease mapping: tools to enhance planning and implementation of a schistosomiasis control programme in Tanzania
    Archie C A Clements
    Schistosomiasis Control Initiative, Imperial College London, London, UK
    Trop Med Int Health 11:490-503. 2006
    ..To predict the spatial distributions of Schistosoma haematobium and S. mansoni infections to assist planning the implementation of mass distribution of praziquantel as part of an on-going national control programme in Tanzania...
  35. pmc A world malaria map: Plasmodium falciparum endemicity in 2007
    Simon I Hay
    Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute University of Oxford Wellcome TrustCollaborative Programme, Nairobi, Kenya
    PLoS Med 6:e1000048. 2009
    ..It is exactly 40 y since the last global map of malaria endemicity was published. This paper describes the generation of a new world map of Plasmodium falciparum malaria endemicity for the year 2007...
  36. ncbi request reprint Schistosoma mansoni in pregnancy and associations with anaemia in northwest Tanzania
    Antony Ajanga
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 100:59-63. 2006
    ..3%, and 16.4% of women had malaria parasitaemia. Overall, 66.4% of women were anaemic. Increased risk of anaemia was associated with heavy infection with S. mansoni but not hookworm or Plasmodium falciparum parasitaemia...
  37. pmc Implementing school malaria surveys in Kenya: towards a national surveillance system
    Caroline W Gitonga
    Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
    Malar J 9:306. 2010
    ..To design and implement surveys of malaria infection and coverage of malaria control interventions among school children in Kenya in order to contribute towards a nationwide assessment of malaria...
  38. ncbi request reprint Community perception of school-based delivery of anthelmintics in Ghana and Tanzania
    S Brooker
    The Partnership for Child Development, Imperial College School of Medicine, London, UK
    Trop Med Int Health 6:1075-83. 2001
    ....
  39. ncbi request reprint Recent advances in research and control of malaria, leishmaniasis, trypanosomiasis and schistosomiasis
    S L Croft
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    East Mediterr Health J 9:518-33. 2003
    ..Schistosomiasis in the Region is caused by either Schistosoma haematobium or S. mansoni and large-scale control efforts include providing regular treatment to at-risk groups and supporting drug delivery through schools...
  40. pmc The health impact of polyparasitism in humans: are we under-estimating the burden of parasitic diseases?
    R Pullan
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Parasitology 135:783-94. 2008
    ....
  41. pmc Mapping the global distribution of trachoma
    Sarah Polack
    Clinical Research Unit, London School of Hygiene and Tropical Medicine, London, England
    Bull World Health Organ 83:913-9. 2005
    ..Until now, information on trachoma prevalence at within country levels has not been systematically collated, analysed and reported...
  42. ncbi request reprint First nationwide survey of the health of schoolchildren in Chad
    Michael Beasley
    Department of Infectious Disease Epidemiology, Imperial College School of Medicine, London, UK
    Trop Med Int Health 7:625-30. 2002
    ..These data show that there is a high prevalence of helminth infection in Chad, but that treatment for S. haematobium and hookworm should be targeted to different geographical areas...
  43. ncbi request reprint Schistosomes, snails and satellites
    S Brooker
    Department of Infectious Disease Epidemiology, Imperial College School of Medicine, Norfolk Place, W2 1PG, London, UK
    Acta Trop 82:207-14. 2002
    ..Finally, the current practical application of GIS and remote sensing are reviewed in the context of national control programmes...
  44. pmc Wastewater quality and the risk of intestinal nematode infection in sewage farming families in hyderabad, India
    Jeroen H J Ensink
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
    Am J Trop Med Hyg 79:561-7. 2008
    ..2, 95% CI = 1.2-8.6) of A. lumbricoides infection. The findings of the study suggest that the current WHO intestinal nematode guideline of 1 ova/liter is sufficient to protect farmer health...
  45. pmc Human helminth co-infection: analysis of spatial patterns and risk factors in a Brazilian community
    Rachel L Pullan
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Negl Trop Dis 2:e352. 2008
    ..Here, we present an investigation of exposure-related risk factors as sources of heterogeneity in the distribution of co-infection with Necator americanus and Schistosoma mansoni in a region of southeastern Brazil...
  46. pmc Plasmodium infection and its risk factors in eastern Uganda
    Rachel L Pullan
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 9:2. 2010
    ..This report presents results from a total population survey of malaria infection and intervention coverage in a rural area of eastern Uganda, with a specific focus on how risk factors differ between demographic groups in this population...
  47. pmc Human helminth co-infection: no evidence of common genetic control of hookworm and Schistosoma mansoni infection intensity in a Brazilian community
    Rachel L Pullan
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Int J Parasitol 40:299-306. 2010
    ....
  48. ncbi request reprint Epidemiology of anthroponotic cutaneous leishmaniasis in Afghan refugee camps in northwest Pakistan
    Jan Kolaczinski
    HealthNet International, University Town, Peshawar, Pakistan
    Trans R Soc Trop Med Hyg 98:373-8. 2004
    ..Based on the evidence from this study an intervention strategy was formulated for all camps with reported ACL cases. This includes targeting of active cases with insecticide-treated nets, sold at a highly subsidised price...
  49. pmc Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review
    Jennifer L Smith
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    Trop Med Int Health 15:776-95. 2010
    ....
  50. pmc Spatial and genetic epidemiology of hookworm in a rural community in Uganda
    Rachel L Pullan
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Negl Trop Dis 4:e713. 2010
    ..8%. In conclusion, we suggest that host genetic relatedness is not a major determinant of infection intensity in this community, with exposure-related factors playing a greater role...
  51. ncbi request reprint Malaria morbidity among school children living in two areas of contrasting transmission in western Kenya
    Sian E Clarke
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 71:732-8. 2004
    ..Taken together with other published studies, the data suggest that malaria morbidity among school age children increases as transmission intensity decreases. The implications for malaria control are discussed...
  52. pmc Heritability of Plasmodium parasite density in a rural Ugandan community
    Rachel L Pullan
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 83:990-5. 2010
    ....
  53. pmc Heterogeneities and consequences of Plasmodium species and hookworm coinfection: a population based study in Uganda
    Rachel L Pullan
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 203:406-17. 2011
    ..In this study, we investigate spatial and household heterogeneities, predictors, and consequences of Plasmodium species and hookworm coinfection in rural communities in Uganda...
  54. ncbi request reprint Malaria control in Afghanistan: progress and challenges
    Jan Kolaczinski
    Disease Control and Vector Biology Unit, London School of Hygiene and Tropical Medicine, London, UK
    Lancet 365:1506-12. 2005
    ..This process should be guided by the knowledge and experience gained during the complex emergency and a focus on malaria should be maintained until the disease is brought under control...
  55. pmc Effect of intermittent preventive treatment of malaria on health and education in schoolchildren: a cluster-randomised, double-blind, placebo-controlled trial
    Sian E Clarke
    London School of Hygiene and Tropical Medicine, London, UK
    Lancet 372:127-38. 2008
    ..We examined the effect of intermittent preventive treatment (IPT) in reducing anaemia and improving classroom attention and educational achievement in semi-immune schoolchildren in an area of high perennial transmission...
  56. ncbi request reprint Repeatability of paired counts
    Neal Alexander
    London School of Hygiene and Tropical Medicine, London, UK
    Stat Med 26:3566-77. 2007
    ..e. the square of the average of square roots. As well as being more easily interpretable, the back-transformed results highlight the dependence of the repeatability on the sample volume used...
  57. pmc Spatial modelling of soil-transmitted helminth infections in Kenya: a disease control planning tool
    Rachel L Pullan
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Negl Trop Dis 5:e958. 2011
    ..Here we present a new approach for mapping the observed prevalence of STHs, using the example of Kenya in 2009...
  58. pmc Tools from ecology: useful for evaluating infection risk models?
    Simon Brooker
    Dept of Infectious Disease Epidemiology, Imperial College School of Medicine, Norfolk Place, W2 1PG, London, UK
    Trends Parasitol 18:70-4. 2002
    ..Using the example of Schistosoma haematobium in Africa, this article illustrates how ecozonation and receiver-operator characteristic analysis can help to assess the usefulness of available models objectively...
  59. pmc Leishmaniasis in refugee and local Pakistani populations
    Simon Brooker
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    Emerg Infect Dis 10:1681-4. 2004
    ..Results suggested similar patterns of endemicity in both Afghan refugee and Pakistani populations and highlighted risk factors and household clustering of disease...
  60. pmc Human hookworm infection in the 21st century
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Adv Parasitol 58:197-288. 2004
    ..There are also on-going efforts to develop novel anthelmintic drugs and anti-hookworm vaccines...
  61. pmc Optimal survey designs for targeting chemotherapy against soil-transmitted helminths: effect of spatial heterogeneity and cost-efficiency of sampling
    Hugh J W Sturrock
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 82:1079-87. 2010
    ....
  62. ncbi request reprint Soil-transmitted helminth infections: updating the global picture
    Nilanthi R de Silva
    Department of Parasitology, Faculty of Medicine, University of Kelaniya, PO Box 6, Ragama, Sri Lanka
    Trends Parasitol 19:547-51. 2003
  63. pmc Impact of a national helminth control programme on infection and morbidity in Ugandan schoolchildren
    Narcis B Kabatereine
    Vector Control Division, Ministry of Health, Kampala, Uganda
    Bull World Health Organ 85:91-9. 2007
    ..We aimed to assess the health impact of a national control programme targeting schistosomiasis and intestinal nematodes in Uganda, which has provided population-based anthelmintic chemotherapy since 2003...
  64. pmc Neglected tropical diseases in Uganda: the prospect and challenge of integrated control
    Jan H Kolaczinski
    Malaria Consortium Africa, Sturrock Road, PO Box 8045, Kampala, Uganda
    Trends Parasitol 23:485-93. 2007
    ....
  65. ncbi request reprint Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa
    Marieke J van der Werf
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
    Acta Trop 86:125-39. 2003
    ..mansoni) at 150000 and 130000 per year. Given the overall high number of cases with schistosomiasis-related disease and associated death, we conclude that schistosomiasis remains an important public health problem in sub-Saharan Africa...
  66. pmc Use of remote sensing and a geographical information system in a national helminth control programme in Chad
    Simon Brooker
    Department of Infectious Disease Epidemiology, Imperial College School of Medicine, London, England
    Bull World Health Organ 80:783-9. 2002
    ....
  67. ncbi request reprint Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm
    Jeffrey Bethony
    Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, 20037, USA
    Lancet 367:1521-32. 2006
    ..Concerns about the sustainability of periodic deworming with benzimidazole anthelmintics and the emergence of resistance have prompted efforts to develop and test new control tools...
  68. ncbi request reprint Exposure to Schistosoma mansoni infection in a rural area in Brazil. Part III: household aggregation of water-contact behaviour
    Jeffrey Bethony
    Department of Microbiology and Tropical Medicine, The George Washington University Medical Center, Washington, DC 20037, USA
    Trop Med Int Health 9:381-9. 2004
    ..Our results also support a focus on the household in the implementation of schistosomiasis prevention and control efforts...
  69. ncbi request reprint Epidemiology and geography of Schistosoma mansoni in Uganda: implications for planning control
    Narcis B Kabatereine
    Vector Control Division, Ministry of Health, Kampala, Uganda
    Trop Med Int Health 9:372-80. 2004
    ..The results are discussed in reference to the ecology of infection and provide an epidemiological framework for the design and implementation of control efforts underway in Uganda...
  70. pmc Age patterns in undernutrition and helminth infection in a rural area of Brazil: associations with ascariasis and hookworm
    Anne Jardim-Botelho
    Instituto René Rachou, Fundação Oswaldo Cruz FIOCUZ, Belo Horizonte, Minas Gerais, Brazil
    Trop Med Int Health 13:458-67. 2008
    ..To investigate the nutritional status of individuals from a rural area of Brazil, and associations with helminth infections in an age-stratified sample...
  71. ncbi request reprint Hookworm infection
    Peter J Hotez
    Department of Microbiology and Tropical Medicine, George Washington University, Washington, DC 20037, USA
    N Engl J Med 351:799-807. 2004
  72. ncbi request reprint Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals
    Jeffrey Bethony
    Department of Microbiology and Tropical Medicine, The George Washington University, Washington, DC 20037, USA
    FASEB J 19:1743-5. 2005
    ..These findings provide strong support for the development of an effective recombinant vaccine against hookworm infection in humans...
  73. pmc Risk factors of visceral leishmaniasis in East Africa: a case-control study in Pokot territory of Kenya and Uganda
    Jan H Kolaczinski
    Malaria Consortium Africa, Plot 2A, Sturrock Road, PO Box 8045, Kampala, Uganda
    Int J Epidemiol 37:344-52. 2008
    ..The present study was conducted to establish the necessary evidence-base and to stimulate interest in supporting the control of this neglected tropical disease in Uganda and Kenya...
  74. ncbi request reprint Progress towards countrywide control of schistosomiasis and soil-transmitted helminthiasis in Uganda
    Narcis B Kabatereine
    Vector Control Division, Ministry of Health, Kampala, Uganda
    Trans R Soc Trop Med Hyg 100:208-15. 2006
    ..As a way forward, it is suggested that the Ministry of Health should integrate deworming into the existing health infrastructure so that every time a child is reached for any health service, the child is also de-wormed...
  75. ncbi request reprint Helminth infections of children: prospects for control
    Peter J Hotez
    Department of Microbiology and Tropical Medicine, The George Washington University Medical Center, Washington, DC 20037, USA
    Adv Exp Med Biol 568:135-44. 2005
  76. ncbi request reprint New technologies for the control of human hookworm infection
    Peter J Hotez
    Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, 2300 I Street, NW Washington, DC 20037, USA
    Trends Parasitol 22:327-31. 2006
    ..g. tribendimidine) and a recombinant hookworm vaccine. It is hoped that, ultimately, anthelmintic vaccination will be linked to deworming as part of an expanded control package...
  77. pmc Hookworm: "the great infection of mankind"
    Peter J Hotez
    Department of Microbiology and Tropical Medicine, The George Washington University, Washington, DC, USA
    PLoS Med 2:e67. 2005
  78. ncbi request reprint Hookworm vaccines: past, present, and future
    Alex Loukas
    Division of Infectious Diseases and Immunology, Queensland Institute of Medical Research, Brisbane, Australia
    Lancet Infect Dis 6:733-41. 2006
    ..The roadmap also addresses the obstacles facing development of a vaccine for developing countries, where there is no commercial market...
  79. pmc Kala-azar control, Uganda
    Jan H Kolaczinski
    Emerg Infect Dis 13:507-9. 2007
  80. ncbi request reprint Cutaneous leishmaniasis
    Richard Reithinger
    Clinical Trials Area, Westat, Rockville, MD 20850, USA
    Lancet Infect Dis 7:581-96. 2007
    ..Disease prevention and control are difficult because of the complexity of cutaneous leishmaniasis epizoology, and the few options available for effective vector control...
  81. ncbi request reprint Eliminating neglected diseases in Africa
    Peter Hotez
    Lancet 365:2089. 2005