Helen Jones

Summary

Affiliation: Liverpool John Moores University
Country: UK

Publications

  1. doi request reprint Post-exercise blood pressure reduction is greater following intermittent than continuous exercise and is influenced less by diurnal variation
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Chronobiol Int 26:293-306. 2009
  2. pmc Nitric oxide-mediated cutaneous microvascular function is impaired in polycystic ovary sydrome but can be improved by exercise training
    V S Sprung
    H Jones Research Institute for Sport and Exercise Sciences, Tom Reilly Building, Liverpool John Moores University, Byrom Street Campus, Liverpool L3 3AF, UK
    J Physiol 591:1475-87. 2013
  3. doi request reprint Diurnal variation in vascular function: role of sleep
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom
    Chronobiol Int 29:271-7. 2012
  4. doi request reprint Effects of time of day on post-exercise blood pressure: circadian or sleep-related influences?
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Chronobiol Int 25:987-98. 2008
  5. doi request reprint Exercise intensity and blood pressure during sleep
    H Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Int J Sports Med 30:94-9. 2009
  6. ncbi request reprint The acute post-exercise response of blood pressure varies with time of day
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Henry Cotton Campus, Webster Street, Liverpool L3 2ET, UK
    Eur J Appl Physiol 104:481-9. 2008
  7. ncbi request reprint Intermittent exercise abolishes the diurnal variation in endothelial-dependent flow-mediated dilation in humans
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores Univ, Henry Cotton Campus, Webster St, Liverpool L3 2ET, UK
    Am J Physiol Regul Integr Comp Physiol 298:R427-32. 2010
  8. doi request reprint α1-Adrenoreceptor activity does not explain lower morning endothelial-dependent, flow-mediated dilation in humans
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, United Kingdom
    Am J Physiol Regul Integr Comp Physiol 300:R1437-42. 2011
  9. doi request reprint Evidence for a greater elevation in vascular shear stress after morning exercise
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Med Sci Sports Exerc 41:1188-93. 2009
  10. ncbi request reprint Exercise training in polycystic ovarian syndrome enhances flow-mediated dilation in the absence of changes in fatness
    Victoria S Sprung
    1Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UNITED KINGDOM 2Department of Diabetes and Endocrinology, University Hospital Aintree, Liverpool, UNITED KINGDOM 3School of Sports Science, Exercise and Health, University of Western Australia, Crawley, Western Australia, AUSTRALIA 4Department of Gynaecology, Liverpool Women s Hospital, Liverpool, United Kingdom and, 5Magnetic Resonance and Image Analysis Research Centre and Department of Musculoskeletal Biology, University of Liverpool, United Kingdom
    Med Sci Sports Exerc 45:2234-42. 2013

Collaborators

Detail Information

Publications34

  1. doi request reprint Post-exercise blood pressure reduction is greater following intermittent than continuous exercise and is influenced less by diurnal variation
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Chronobiol Int 26:293-306. 2009
    ..Therefore, a bout of afternoon exercise that is occasionally interrupted with short rest periods is recommended for lowering BP acutely...
  2. pmc Nitric oxide-mediated cutaneous microvascular function is impaired in polycystic ovary sydrome but can be improved by exercise training
    V S Sprung
    H Jones Research Institute for Sport and Exercise Sciences, Tom Reilly Building, Liverpool John Moores University, Byrom Street Campus, Liverpool L3 3AF, UK
    J Physiol 591:1475-87. 2013
    ..6% CVCmax (95% confidence interval, 4.3, 34.9; P = 0.02). Cutaneous microvascular NO function is impaired in women with PCOS compared with obese matched control women but can be improved with exercise training...
  3. doi request reprint Diurnal variation in vascular function: role of sleep
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom
    Chronobiol Int 29:271-7. 2012
    ..These findings also raise the possibility of a lower homeostatic "set point" for vascular function following a period of sleep and in the absence of perturbing hemodynamic fluctuation...
  4. doi request reprint Effects of time of day on post-exercise blood pressure: circadian or sleep-related influences?
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Chronobiol Int 25:987-98. 2008
    ..This phenomenon cannot be attributed simply to the residual effects of sleep, as it was not observed when participants exercised after a period of daytime sleep...
  5. doi request reprint Exercise intensity and blood pressure during sleep
    H Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Int J Sports Med 30:94-9. 2009
    ..1 to - 0.1). We conclude that daytime exercise can elicit a physiologically meaningful lower BP during sleep and exercise intensity is the most important factor in this phenomenon...
  6. ncbi request reprint The acute post-exercise response of blood pressure varies with time of day
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Henry Cotton Campus, Webster Street, Liverpool L3 2ET, UK
    Eur J Appl Physiol 104:481-9. 2008
    ..We conclude that the acutely hypotensive effects following 30 min of steady state exercise are less marked in the morning, probably because the exercise-mediated decrease in peripheral resistance is not as apparent at this time of day...
  7. ncbi request reprint Intermittent exercise abolishes the diurnal variation in endothelial-dependent flow-mediated dilation in humans
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores Univ, Henry Cotton Campus, Webster St, Liverpool L3 2ET, UK
    Am J Physiol Regul Integr Comp Physiol 298:R427-32. 2010
    ..This infers a reduced function of the intrinsic endothelial NO-vasodilator system in the morning. We also report, for the first time, that a bout of intermittent exercise abolishes this diurnal variation in endothelium-dependent FMD...
  8. doi request reprint α1-Adrenoreceptor activity does not explain lower morning endothelial-dependent, flow-mediated dilation in humans
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, United Kingdom
    Am J Physiol Regul Integr Comp Physiol 300:R1437-42. 2011
    ..34). Heart rate and norepinephrine levels were higher in the afternoon following prazosin. These data indicate that α(1)-adrenoreceptor activity does not explain lower morning endothelium-dependent FMD...
  9. doi request reprint Evidence for a greater elevation in vascular shear stress after morning exercise
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Med Sci Sports Exerc 41:1188-93. 2009
    ..The aim of this study was to assess vascular responses after exercise at different times of day...
  10. ncbi request reprint Exercise training in polycystic ovarian syndrome enhances flow-mediated dilation in the absence of changes in fatness
    Victoria S Sprung
    1Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UNITED KINGDOM 2Department of Diabetes and Endocrinology, University Hospital Aintree, Liverpool, UNITED KINGDOM 3School of Sports Science, Exercise and Health, University of Western Australia, Crawley, Western Australia, AUSTRALIA 4Department of Gynaecology, Liverpool Women s Hospital, Liverpool, United Kingdom and, 5Magnetic Resonance and Image Analysis Research Centre and Department of Musculoskeletal Biology, University of Liverpool, United Kingdom
    Med Sci Sports Exerc 45:2234-42. 2013
    ..Therefore, the aim of the current study was to investigate the impact of exercise on endothelial function, in parallel with body composition, insulin resistance, and cardiopulmonary fitness in PCOS...
  11. pmc Circadian variation in the circulatory responses to exercise: relevance to the morning peaks in strokes and cardiac events
    Greg Atkinson
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Eur J Appl Physiol 108:15-29. 2010
    ..We recommend that such 'semi-constant routine' protocols are employed to examine the relative influence of the body clock and exogenous factors on the 24-h variation in other circulatory factors...
  12. ncbi request reprint Influence of cold-water immersion on limb and cutaneous blood flow after exercise
    Chris Mawhinney
    1Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UNITED KINGDOM 2School of Sport Science, Exercise and Health, The University of Western Australia, Perth, AUSTRALIA and Aspire Academy for Sports Excellence, Doha, Qatar
    Med Sci Sports Exerc 45:2277-85. 2013
    ..This study aimed to determine the influence of cold (8°C) and cool (22°C) water immersion on femoral artery and cutaneous blood flow after exercise...
  13. ncbi request reprint Remote ischemic preconditioning prevents reduction in brachial artery flow-mediated dilation after strenuous exercise
    Tom G Bailey
    Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, United Kingdom
    Am J Physiol Heart Circ Physiol 303:H533-8. 2012
    ..4% in healthy men. However, we have shown for the first time that prior RIPC of the lower limbs maintains postexercise brachial artery endothelium-dependent function at preexercise levels...
  14. doi request reprint Endothelial dysfunction in hyperandrogenic polycystic ovary syndrome is not explained by either obesity or ectopic fat deposition
    Victoria S Sprung
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, U K
    Clin Sci (Lond) 126:67-74. 2014
    ..The results suggest that endothelial dysfunction in PCOS is not explained by body fat distribution or volume. FMD might be a useful independent prognostic tool to assess CVD risk in this population. ..
  15. ncbi request reprint 24-hour variation in the reactivity of rate-pressure-product to everyday physical activity in patients attending a hypertension clinic
    Greg Atkinson
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores, Liverpool, UK
    Chronobiol Int 26:958-73. 2009
    ....
  16. doi request reprint Diurnal variation in the mechanical and neural components of the baroreflex
    Chloe E Taylor
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Tom Reilly Building, Byrom Street, Liverpool L3 3AF, United Kingdom
    Hypertension 58:51-6. 2011
    ..Pharmacological and lifestyle interventions targeted specifically at the diminished component of the cardiac baroreflex in the morning may lead to better management of hypertension...
  17. ncbi request reprint Exercise training improves cutaneous microvascular function in nonalcoholic fatty liver disease
    Christopher J A Pugh
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom
    Am J Physiol Endocrinol Metab 305:E50-8. 2013
    ..02). Exercise training improves cutaneous microvascular NO function in NAFLD patients. The benefit of exercise training compared with conventional care strongly supports a role for exercise in the prevention of CVD in NAFLD...
  18. doi request reprint Effect of ischemic preconditioning on lactate accumulation and running performance
    Tom G Bailey
    Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, England, United Kingdom
    Med Sci Sports Exerc 44:2084-9. 2012
    ..Therefore, we examined the potential of IPC to improve 5-km running time trial performance and reduce lactate accumulation during an incremental exercise test...
  19. doi request reprint Influence of cold water immersion on limb and cutaneous blood flow at rest
    Warren Gregson
    Warren Gregson, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool L3 3AF UK
    Am J Sports Med 39:1316-23. 2011
    ..Benefits may partly arise from a decline in limb blood flow; however, no study has comprehensively investigated the influence of different degrees of cooling undertaken via cold water immersion on limb blood flow responses...
  20. ncbi request reprint Is the ratio of flow-mediated dilation and shear rate a statistically sound approach to normalization in cross-sectional studies on endothelial function?
    Greg Atkinson
    1Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom
    J Appl Physiol (1985) 107:1893-9. 2009
    ..If the relationship between SR and FMD is generally found to be weak or nonlinear or variable between samples, then ratio normalization should not be applied...
  21. ncbi request reprint Is the magnitude of acute post-exercise hypotension mediated by exercise intensity or total work done?
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Eur J Appl Physiol 102:33-40. 2007
    ..0005). The acute post-exercise reduction in BP was clinically similar following high intensity short duration exercise and moderate intensity longer duration exercise that was matched for total work done...
  22. doi request reprint Is flow-mediated dilation nitric oxide mediated?: A meta-analysis
    Daniel J Green
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Tom Reilly Bldg, Byrom St, L3 3AF Liverpool, United Kingdom
    Hypertension 63:376-82. 2014
    ..9% [95% CI, 6.0%-7.8%]; FMD(L-NMMA), 2.4% [95% CI, 1.1%-3.7%]; P<0.001). This comprehensive analysis demonstrates that FMD of conduit arteries in humans is, at least in part, mediated by NO...
  23. pmc Prior exercise lowers blood pressure during simulated night-work with different meal schedules
    Sarah Fullick
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Am J Hypertens 22:835-41. 2009
    ..We present the first investigation into the acute effects of exercise on BP monitored during simulated night-work...
  24. doi request reprint Changes in vascular and cardiac function after prolonged strenuous exercise in humans
    Ellen A Dawson
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, 15 21 Webster St, Liverpool L3 2ET, UK
    J Appl Physiol (1985) 105:1562-8. 2008
    ..In conclusion, when taken together, these data suggest a transient depression in cardiac and leg vascular function following prolonged intensive exercise...
  25. ncbi request reprint Reactivity of ambulatory blood pressure to physical activity varies with time of day
    Helen Jones
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool L3 2ET, United Kingdom
    Hypertension 47:778-84. 2006
    ..485), medication use, age, and sex (P>0.350). In conclusion, under conditions of normal living, the reactivity of BP and HR to a given unit change in activity is highest in the morning and shows a secondary rise in the afternoon...
  26. ncbi request reprint Appropriate within-subjects statistical models for the analysis of baroreflex sensitivity
    Greg Atkinson
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Clin Physiol Funct Imaging 31:80-2. 2011
    ....
  27. ncbi request reprint Acute changes in cardiovascular function during the onset period of daytime sleep: comparison to lying awake and standing
    Mohammad Zaregarizi
    Research Institute for Sport and Exercise Sciences, Henry Cotton Campus, Liverpool John Moores Univ, Liverpool L3 2ET, UK
    J Appl Physiol 103:1332-8. 2007
    ..05). Our findings suggest that the period between lights out and sleep onset is associated with the largest acute reduction in blood pressure during one afternoon siesta...
  28. ncbi request reprint Seven-day remote ischemic preconditioning improves local and systemic endothelial function and microcirculation in healthy humans
    Helen Jones
    Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK
    Am J Hypertens 27:918-25. 2014
    ..The purpose was to examine the hypothesis that daily IPC leads to improvement in endothelial function and skin microcirculation not only in the arm exposed to IPC but also in the contralateral arm...
  29. doi request reprint Endothelial function measured using flow-mediated dilation in polycystic ovary syndrome: a meta-analysis of the observational studies
    Victoria S Sprung
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Clin Endocrinol (Oxf) 78:438-46. 2013
    ..The aims of this systematic review and meta-analysis were to examine to what extent FMD is impaired in PCOS and to explore the influence of potential moderators of FMD reduction, such as age and BMI...
  30. doi request reprint Flow-mediated dilation and cardiovascular event prediction: does nitric oxide matter?
    Daniel J Green
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Tom Reilly Building, Byrom Street, Liverpool L3 3AF, UK
    Hypertension 57:363-9. 2011
    ..Although this finding should be confirmed with more and larger studies, we suggest that any direct measure of vascular (endothelial) function may provide independent prognostic information in humans...
  31. doi request reprint Within-subject correlations between evening-related changes in body temperature and melatonin in the spinal cord injured
    Helen Jones
    Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK
    Chronobiol Int 31:157-65. 2014
    ..In order to examine whether this finding relates to circadian thermoregulation, we compared the correlations between evening changes in melatonin, core and skin temperature between thoracic and cervical SCI and able-bodied participants...
  32. doi request reprint Abnormalities of vascular structure and function in children with Perthes disease
    Daniel C Perry
    Department of Public Health and Policy, University of Liverpool, Liverpool, United Kingdom
    Pediatrics 130:e126-31. 2012
    ..This study sought to use ultrasound measures to investigate vascular structure and function in children affected by Perthes disease...
  33. ncbi request reprint Promoting physical activity in women: evaluation of a 2-year community-based intervention in Sydney, Australia
    Li Ming Wen
    Health Promotion Unit, Central Sydney Area Health Service, L4 Queen Mary Building, Grose St, Camperdown, NSW 2050, Australia
    Health Promot Int 17:127-37. 2002
    ....
  34. pmc The effects of heparin and related molecules on vascular permeability and neutrophil accumulation in rabbit skin
    Helen Jones
    Sackler Institute of Pulmonary Pharmacology, GKT School of Biomedical Sciences, 5th Floor Hodgkin Building, King s College London, Guy s Campus, London SE1 9RT
    Br J Pharmacol 135:469-79. 2002
    ..The lack of effect of exogenous heparin on acute inflammatory responses induced by allergen, suggests that cationic proteins are unlikely to be primary mediators of the allergen-induced PE or PMN accumulation...