Research Topics
| A Li-Wan-PoSummaryCountry: UK Publications
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Publications
How high should total pain-relief score be to obviate the need for analgesic remedication in acute pain? Estimation using signal detection theory and individual-patient meta-analysisA Li Wan Po
Centre for Evidence Based Pharmacotherapy, Nottingham, UK
J Clin Pharm Ther 31:161-5. 2006..A pain relief score 50% of the maximum is often used as a clinically meaningful outcome in meta-analyses of analgesic trials. This arbitrary value requires validation...
Dose-response of minor analgesics in acute painAlain Li Wan Po
National Genetics Education and Development Centre, Birmingham and Centre for Evidence-Based Pharmacotherapy, Nottingham, UK
Br J Clin Pharmacol 63:268-70. 2007
Personalised medicine: who is an Asian?Alain Li Wan Po
National Genetics Education and Development Centre, Birmingham, UK
Lancet 369:1770-1. 2007
Integrating pharmacogenetics and therapeutic drug monitoring: optimal dosing of imatinib as a case-exampleAlain Li-Wan-Po
National Genetics Education and Development Centre, c o Birmingham Women s Hospital, Edgbaston, UK
Eur J Clin Pharmacol 66:369-74. 2010..To illustrate the interface of pharmacogenetics and therapeutic drug monitoring and to estimate target blood level for imatinib in the treatment of chronic myelogenous leukemia..
Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19*17Alain Li-Wan-Po
National Genetics Education and Development Centre, c o Birmingham Women s Hospital, UK
Br J Clin Pharmacol 69:222-30. 2010..Investigators disagree about the phenotype to be assigned to the two CYP2C19*17 genotypes. The aim of this study was to provide a critical summary, helpful to prescribers...
Preventing the aortic complications of Marfan syndrome: a case-example of translational genomic medicineAlain Li-Wan-Po
National Genetics Education and Development Centre, Morris House, c o Birmingham Women s Hospital, Edgbaston, Birmingham, United Kingdom
Br J Clin Pharmacol 72:6-17. 2011..If on-going well designed trials confirm their efficacy, the outlook for Marfan syndrome patients would be improved considerably...
Barking up the wrong genome--we are not aloneA Li-Wan-Po
National Genetics Education and Development Centre, c o Birmingham s Women s Hospital, Edgbaston, Birmingham, UK
J Clin Pharm Ther 36:125-7. 2011..Here, we wish to draw attention to how our microbiome may contribute to variability in drug effects...
