M J Lehane

Summary

Country: UK

Publications

  1. pmc Midgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans
    M J Lehane
    School of Biological Sciences, University of Wales, Bangor, LL57 2UW, United Kingdom
    Proc Natl Acad Sci U S A 94:11502-7. 1997
  2. ncbi Cloning, sequencing, temporal expression and tissue-specificity of two serine proteases from the midgut of the blood-feeding fly Stomoxys calcitrans
    S M Lehane
    School of Biological Sciences, University of Wales, Bangor, UK
    Eur J Biochem 254:290-6. 1998
  3. ncbi Grouping of trypanosome species in mixed infections in Glossina pallidipes
    M J Lehane
    School of Biological Sciences, University of Wales, Bangor, UK
    Parasitology 120:583-92. 2000
  4. pmc Adult midgut expressed sequence tags from the tsetse fly Glossina morsitans morsitans and expression analysis of putative immune response genes
    M J Lehane
    School of Biological Sciences, University of Wales, Bangor, LL57 2UW, UK
    Genome Biol 4:R63. 2003
  5. ncbi Antioxidant gene expression in the blood-feeding fly Glossina morsitans morsitans
    R J L Munks
    School of Biological Sciences, University of Wales, Bangor, Gwynedd, UK
    Insect Mol Biol 14:483-91. 2005
  6. ncbi Association of midgut defensin with a novel serine protease in the blood-sucking fly Stomoxys calcitrans
    J V Hamilton
    School of Biological Sciences, University of Wales, Bangor UK
    Insect Mol Biol 11:197-205. 2002
  7. ncbi Regulation of midgut defensin production in the blood-sucking insect Stomoxys calcitrans
    R J Munks
    School of Biological Sciences, University of Wales, Bangor LL57 2UW, Wales, UK
    Insect Mol Biol 10:561-71. 2001

Collaborators

Detail Information

Publications7

  1. pmc Midgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans
    M J Lehane
    School of Biological Sciences, University of Wales, Bangor, LL57 2UW, United Kingdom
    Proc Natl Acad Sci U S A 94:11502-7. 1997
    ..These findings suggest that the insect midgut has its own tissue-specific immune mechanisms and that this invertebrate epithelium is, like several vertebrate epithelia, protected by specific antibacterial peptides...
  2. ncbi Cloning, sequencing, temporal expression and tissue-specificity of two serine proteases from the midgut of the blood-feeding fly Stomoxys calcitrans
    S M Lehane
    School of Biological Sciences, University of Wales, Bangor, UK
    Eur J Biochem 254:290-6. 1998
    ....
  3. ncbi Grouping of trypanosome species in mixed infections in Glossina pallidipes
    M J Lehane
    School of Biological Sciences, University of Wales, Bangor, UK
    Parasitology 120:583-92. 2000
    ..05). If confirmed in other studies these findings have serious implications for our understanding of trypanosome epidemiology in tsetse flies, much of which is founded on data from dissection-based trypanosome identifications...
  4. pmc Adult midgut expressed sequence tags from the tsetse fly Glossina morsitans morsitans and expression analysis of putative immune response genes
    M J Lehane
    School of Biological Sciences, University of Wales, Bangor, LL57 2UW, UK
    Genome Biol 4:R63. 2003
    ..We have undertaken an expressed sequence tag (EST) project on the adult tsetse midgut, the major organ system for establishment and early development of trypanosomes...
  5. ncbi Antioxidant gene expression in the blood-feeding fly Glossina morsitans morsitans
    R J L Munks
    School of Biological Sciences, University of Wales, Bangor, Gwynedd, UK
    Insect Mol Biol 14:483-91. 2005
    ..Overall, nine of the 11 genes studied showed responses to changes in physiological circumstance, with the peroxiredoxin group showing the smallest variations throughout...
  6. ncbi Association of midgut defensin with a novel serine protease in the blood-sucking fly Stomoxys calcitrans
    J V Hamilton
    School of Biological Sciences, University of Wales, Bangor UK
    Insect Mol Biol 11:197-205. 2002
    ..This > 26 kDa protein (Ssp3) has been cloned and sequenced and is a member of the serine protease S1 family with homologies to multiple insect proteases and to vertebrate trypsins and elastases...
  7. ncbi Regulation of midgut defensin production in the blood-sucking insect Stomoxys calcitrans
    R J Munks
    School of Biological Sciences, University of Wales, Bangor LL57 2UW, Wales, UK
    Insect Mol Biol 10:561-71. 2001
    ..Electrophoretic mobility shift assays (EMSA) suggest the rel-like sites in the proximal promoter region of Smd genes do not bind midgut factors and so are non-functional...