Peter Langhorne

Summary

Country: UK

Publications

  1. ncbi Applicability of stroke-unit care to low-income and middle-income countries
    Peter Langhorne
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Lancet Neurol 11:341-8. 2012
  2. doi Stroke rehabilitation
    Peter Langhorne
    Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Royal Infirmary, Glasgow, UK
    Lancet 377:1693-702. 2011
  3. doi Socioeconomic status and transient ischaemic attack/stroke: a prospective observational study
    Gillian D Kerr
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK
    Cerebrovasc Dis 31:130-7. 2011
  4. ncbi Estimating the impact of stroke unit care in a whole population: an epidemiological study using routine data
    Peter Langhorne
    Cardiovascular and Medical Sciences Division, University of Glasgow, Glasgow, UK
    J Neurol Neurosurg Psychiatry 81:1301-5. 2010
  5. pmc Trends in incidence and in short term survival following a subarachnoid haemorrhage in Scotland, 1986-2005: a retrospective cohort study
    Karen J Macpherson
    NHS Quality Improvement Scotland, Glasgow, UK
    BMC Neurol 11:38. 2011
  6. doi Interventions for age-related visual problems in patients with stroke
    Alex Pollock
    Nursing, Midwifery and AlliedHealth Professions Research Unit, Glasgow Caledonian University, Glasgow, UK
    Cochrane Database Syst Rev 3:CD008390. 2012
  7. pmc Temporal trends in hospitalisation for stroke recurrence following incident hospitalisation for stroke in Scotland
    James Lewsey
    Public Health and Health Policy, University of Glasgow, Glasgow, UK
    BMC Med 8:23. 2010
  8. ncbi Interventions for disorders of eye movement in patients with stroke
    Alex Pollock
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Buchanan House, Cowcaddens Road, Glasgow, UK, G4 0BA
    Cochrane Database Syst Rev 10:CD008389. 2011
  9. doi Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke
    Paul Welsh
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
    Cerebrovasc Dis 27:247-53. 2009
  10. doi Stroke unit care benefits patients with intracerebral hemorrhage: systematic review and meta-analysis
    Peter Langhorne
    From the Academic Section of Geriatric Medicine, Royal Infirmary, Glasgow, United Kingdom P L, P F Department of Neurology, Akershus University Hospital, Norway O M R Department of Neurology, Helsinki University Central Hospital, Finland M K, H P Acute Stroke Unit, Department of Clinical Therapeutics, School of Medicine, University of Ioannina, Greece K V Department of Stroke Medicine, King s College Hospital, London, United Kingdom L K Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway B I Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Goteborg University, Sweden C B Institute of Ageing and Health, Medical School, Newcastle upon Tyne, United Kingdom H R and Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom M S D, R A S S
    Stroke 44:3044-9. 2013

Detail Information

Publications48

  1. ncbi Applicability of stroke-unit care to low-income and middle-income countries
    Peter Langhorne
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Lancet Neurol 11:341-8. 2012
    ..Although substantial challenges are present to the development of stroke units more widely across the world, the potential gains from such developments are substantial...
  2. doi Stroke rehabilitation
    Peter Langhorne
    Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Royal Infirmary, Glasgow, UK
    Lancet 377:1693-702. 2011
    ....
  3. doi Socioeconomic status and transient ischaemic attack/stroke: a prospective observational study
    Gillian D Kerr
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK
    Cerebrovasc Dis 31:130-7. 2011
    ..We aimed to determine whether low-SES stroke/transient ischaemic attack (TIA) patients have a greater burden of vascular risk factors/co-morbidity and reduced health care access...
  4. ncbi Estimating the impact of stroke unit care in a whole population: an epidemiological study using routine data
    Peter Langhorne
    Cardiovascular and Medical Sciences Division, University of Glasgow, Glasgow, UK
    J Neurol Neurosurg Psychiatry 81:1301-5. 2010
    ..However, it is unclear what impact this complex intervention actually has in routine practice. A comprehensive national dataset was used to study the impact of stroke unit implementation...
  5. pmc Trends in incidence and in short term survival following a subarachnoid haemorrhage in Scotland, 1986-2005: a retrospective cohort study
    Karen J Macpherson
    NHS Quality Improvement Scotland, Glasgow, UK
    BMC Neurol 11:38. 2011
    ..To examine age and sex specific incidence and 30 day case fatality for subarachnoid haemorrhage (SAH) in Scotland over a 20 year period...
  6. doi Interventions for age-related visual problems in patients with stroke
    Alex Pollock
    Nursing, Midwifery and AlliedHealth Professions Research Unit, Glasgow Caledonian University, Glasgow, UK
    Cochrane Database Syst Rev 3:CD008390. 2012
    ..Consequently, the nature and outcome of interventions for age-related visual problems may be different in patients with stroke...
  7. pmc Temporal trends in hospitalisation for stroke recurrence following incident hospitalisation for stroke in Scotland
    James Lewsey
    Public Health and Health Policy, University of Glasgow, Glasgow, UK
    BMC Med 8:23. 2010
    ..The aim of this study was to examine temporal trends in hospitalisation for stroke recurrence following incident hospitalisation for stroke in Scotland during 1986 to 2001...
  8. ncbi Interventions for disorders of eye movement in patients with stroke
    Alex Pollock
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Buchanan House, Cowcaddens Road, Glasgow, UK, G4 0BA
    Cochrane Database Syst Rev 10:CD008389. 2011
    ..However, in the past, there has been a lack of evidence specific to the impact of interventions on the functional outcome of patients with stroke...
  9. doi Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke
    Paul Welsh
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
    Cerebrovasc Dis 27:247-53. 2009
    ..Many inflammatory and haemostatic biomarkers show associations with acute ischaemic stroke outcome, but few studies compare a large range of markers...
  10. doi Stroke unit care benefits patients with intracerebral hemorrhage: systematic review and meta-analysis
    Peter Langhorne
    From the Academic Section of Geriatric Medicine, Royal Infirmary, Glasgow, United Kingdom P L, P F Department of Neurology, Akershus University Hospital, Norway O M R Department of Neurology, Helsinki University Central Hospital, Finland M K, H P Acute Stroke Unit, Department of Clinical Therapeutics, School of Medicine, University of Ioannina, Greece K V Department of Stroke Medicine, King s College Hospital, London, United Kingdom L K Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway B I Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Goteborg University, Sweden C B Institute of Ageing and Health, Medical School, Newcastle upon Tyne, United Kingdom H R and Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom M S D, R A S S
    Stroke 44:3044-9. 2013
    ..However, it is uncertain whether these benefits apply equally to patients with intracerebral hemorrhage and ischemic stroke...
  11. doi Predictors of upper limb recovery after stroke: a systematic review and meta-analysis
    Fiona Coupar
    Glasgow University, Academic Section of Geriatric Medicine, Glasgow, UK
    Clin Rehabil 26:291-313. 2012
    ..To systematically review and summarize the current available literature on prognostic variables relating to upper limb recovery following stroke. To identify which, if any variables predict upper limb recovery following stroke...
  12. pmc Impact of Scotland's comprehensive, smoke-free legislation on stroke
    Daniel F Mackay
    Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom
    PLoS ONE 8:e62597. 2013
    ..Evidence is lacking on whether stroke is also reduced. The aim was to determine whether the incidence of stroke, overall and by sub-type, fell following introduction of smoke-free legislation across Scotland on 26 March 2006...
  13. doi Early mobilization after stroke: an example of an individual patient data meta-analysis of a complex intervention
    Louise E Craig
    College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    Stroke 41:2632-6. 2010
    ..The aim of this analysis was to investigate the impact of VEM on independence by pooling data from these 2 comparable trials...
  14. ncbi Risk factors for chest infection in acute stroke: a prospective cohort study
    Cameron Sellars
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary, Glasgow, UK
    Stroke 38:2284-91. 2007
    ..Pneumonia is a major cause of morbidity and mortality after stroke. We aimed to determine key characteristics that would allow prediction of those patients who are at highest risk for poststroke pneumonia...
  15. ncbi Early supported discharge after stroke
    Peter Langhorne
    Academic Section of Geriatric Medicine, University of Glasgow, Glasgow, UK
    J Rehabil Med 39:103-8. 2007
    ..In conclusion, an illustrative case report is set out, indicating a typical patient pathway in an early supported discharge service...
  16. pmc Developing and evaluating the implementation of a complex intervention: using mixed methods to inform the design of a randomised controlled trial of an oral healthcare intervention after stroke
    Marian C Brady
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Glasgow, UK
    Trials 12:168. 2011
    ..Our aim was to develop and evaluate the implementation of a complex, multidimensional oral health care (OHC) intervention for people in stroke rehabilitation settings which would inform the development of a randomised controlled trial...
  17. ncbi Simultaneous bilateral training for improving arm function after stroke
    Fiona Coupar
    Academic Section of Geriatric Medicine, University of Glasgow, University Block, Glasgow Royal Infirmary, Glasgow, UK, G4 0SF
    Cochrane Database Syst Rev 4:CD006432. 2010
    ..We identified evidence that suggests that bilateral training may be no more (or less) effective than usual care or other upper limb interventions for performance in ADL, functional movement of the upper limb or motor impairment outcomes...
  18. doi Very early rehabilitation or intensive telemetry after stroke: a pilot randomised trial
    Peter Langhorne
    Academic Section of Geriatric Medicine, University of Glasgow, Glasgow, UK p langhorne clinmed gla ac uk
    Cerebrovasc Dis 29:352-60. 2010
    ..However, there are uncertainties about how best to provide such care. We studied 2 key aspects of early stroke unit care: early active mobilisation (EM) and automated monitoring (AM) for physiological complications such as hypoxia...
  19. ncbi Predictive value of newly detected atrial fibrillation paroxysms in patients with acute ischemic stroke, for atrial fibrillation after 90 days
    Peter Higgins
    From the College of Medical, Veterinary and Life Sciences, Institute of Cardiovascular and Medical Sciences P H, J D, P W M, K M, P L, K R L, Gardiner Institute, Western Infirmary P H, J D, K M, K R L, Glasgow Royal Infirmary P W M, P L, University of Glasgow, Glasgow, United Kingdom
    Stroke 45:2134-6. 2014
    ..We evaluated the positive and negative predictive value (PPV and NPV) of AF detection early after AIS, for PAF confirmation 90 days later...
  20. doi Noninvasive cardiac event monitoring to detect atrial fibrillation after ischemic stroke: a randomized, controlled trial
    Peter Higgins
    University of Glasgow, Glasgow, UK
    Stroke 44:2525-31. 2013
    ..We hypothesized that 7 days of noninvasive cardiac-event monitoring early after stroke would accelerate detection of AF and thus uptake of effective therapy...
  21. doi Reliability (inter-rater agreement) of the Barthel Index for assessment of stroke survivors: systematic review and meta-analysis
    Laura Duffy
    Department of Academic Geriatric Medicine, Walton Building, Glasgow Royal Infirmary, Glasgow, G4 0SF United Kingdom
    Stroke 44:462-8. 2013
    ..We sought to describe the reliability (interobserver variability) of standard BI in stroke cohorts using systematic review and meta-analysis of published studies...
  22. ncbi Early supported discharge services for stroke patients: a meta-analysis of individual patients' data
    Peter Langhorne
    Academic Section of Geriatric Medicine, Level 3, Centre Block, Royal Infirmary, Glasgow G4 OSF, UK
    Lancet 365:501-6. 2005
    ..Services have been developed that offer patients early discharge from hospital with rehabilitation at home (early supported discharge [ESD]). We have assessed the effects and costs of such services...
  23. doi Predictors of poststroke mobility: systematic review
    Louise E Craig
    College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    Int J Stroke 6:321-7. 2011
    ..The recovery of mobility other than walking also needs investigation. In order to move prognostic research in stroke forward, a collaborative approach to sharing and collecting data is recommended...
  24. doi Barthel index for stroke trials: development, properties, and application
    Terence J Quinn
    Department of Academic Geriatric Medicine, Institute of Cardiovascular and Medical Services, University of Glasgow, UK
    Stroke 42:1146-51. 2011
    ..Of the various measures available, the Barthel index (BI) is one of the more prevalent. We aimed to describe validity, reliability, and responsiveness (clinimetric properties) of the BI in stroke trials...
  25. doi Do vascular risk factors explain the association between socioeconomic status and stroke incidence: a meta-analysis
    Gillian D Kerr
    Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Cerebrovasc Dis 31:57-63. 2011
    ..Reduced socioeconomic status (SES) is associated with an increased risk of stroke, although the mechanism is not clear. It may be that those with lower SES have a greater burden of classic vascular risk factors...
  26. doi VISTA-Rehab: a resource for stroke rehabilitation trials
    Myzoon Ali
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Glasgow, UK
    Int J Stroke 5:447-52. 2010
    ..We developed an archive of stroke rehabilitation trials (VISTA-Rehab) to act as a resource to help trialists model and design future rehabilitation studies...
  27. ncbi Physical rehabilitation approaches for the recovery of function and mobility following stroke
    Alex Pollock
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Buchanan House, Cowcaddens Road, Glasgow, UK, G4 0BA
    Cochrane Database Syst Rev 4:CD001920. 2014
    ..Some physiotherapists base their treatments on a single approach; others use a mixture of components from several different approaches...
  28. ncbi Approaches to economic evaluations of stroke rehabilitation
    Louise E Craig
    College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    Int J Stroke 9:88-100. 2014
    ....
  29. ncbi WITHDRAWN: Services for helping acute stroke patients avoid hospital admission
    Peter Langhorne
    Academic Section of Geriatric Medicine, University of Glasgow, 3rd Floor, Centre Block, RoyalInfirmary, Glasgow, G4 0SF, UK
    Cochrane Database Syst Rev 1:CD000444. 2012
    ..Stroke patients are usually admitted to hospital for their acute care and rehabilitation. Services to help acute stroke patients avoid admission to hospital ('hospital-at-home') have now been developed...
  30. ncbi Stroke units in their natural habitat: systematic review of observational studies
    Pamela Seenan
    Academic Section of Geriatric Medicine, Royal Infirmary, Glasgow, UK
    Stroke 38:1886-92. 2007
    ..However, there are concerns that the benefits seen in clinical trials may not be replicated in routine practice. We carried out a systematic review of observational studies of stroke unit implementation...
  31. doi Multidisciplinary care for elderly people in the community
    David J Stott
    Academic Section of Geriatric Medicine, University of Glasgow Faculty of Medicine, Glasgow Royal Infirmary, Glasgow G31 2ER, UK
    Lancet 371:699-700. 2008
  32. ncbi Does the prevention of complications explain the survival benefit of organized inpatient (stroke unit) care?: further analysis of a systematic review
    Lindsay Govan
    Academic Section of Geriatric Medicine, University Block, Glasgow Royal Infirmary, Glasgow, UK
    Stroke 38:2536-40. 2007
    ..However, it is unclear how this is achieved. We tested whether stroke unit care could reduce deaths by preventing complications...
  33. ncbi Non-pharmacological interventions for caregivers of stroke survivors
    Lynn A Legg
    Academic Section of Geriatric Medicine, Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Room 5, 4th Floor, Walton Building, Royal Infirmary, Glasgow, UK, G4 0SF
    Cochrane Database Syst Rev 10:CD008179. 2011
    ..A range of interventions targeted towards stroke survivors and their family or other informal caregivers have been tested in randomised controlled trials (RCTs). ..
  34. ncbi Physiotherapy treatment approaches for the recovery of postural control and lower limb function following stroke: a systematic review
    Alex Pollock
    Stroke Therapy Evaluation Programme, Academic Section of Geriatric Medicine, Glasgow Royal Infirmary, Glasgow, UK
    Clin Rehabil 21:395-410. 2007
    ..To determine whether there is a difference in global dependency and functional independence in patients with stroke associated with different approaches to physiotherapy treatment...
  35. doi Services for reducing duration of hospital care for acute stroke patients
    Patricia Fearon
    Academic Section of Geriatric Medicine, University of Glasgow, Glasgow, UK
    Cochrane Database Syst Rev 9:CD000443. 2012
    ..Services have now been developed which offer patients in hospital an early discharge with rehabilitation at home (early supported discharge (ESD))...
  36. ncbi Comprehensive geriatric assessment for older hospital patients
    Graham Ellis
    Academic Section of Geriatric Medicine, University of Glasgow, Level 3, Centre Block, Royal Infirmary, Glasgow G4 0SF, UK
    Br Med Bull 71:45-59. 2004
    ..However, CGA does not reduce long-term mortality. This evidence should inform future service developments...
  37. ncbi Motor recovery after stroke: a systematic review
    Peter Langhorne
    Stroke Therapy Evaluation Programme, Academic Section of Geriatric Medicine, Cardiovascular and Medical Sciences Division, Royal Infirmary, Glasgow, UK
    Lancet Neurol 8:741-54. 2009
    ..Although the existing evidence is limited by poor trial designs, some treatments do show promise for improving motor recovery, particularly those that have focused on high-intensity and repetitive task-specific practice...
  38. ncbi D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays
    Mark Barber
    University Section of Clinical Gerontology and Vascular Medicine, Royal Infirmary, Glasgow, UK
    Stroke 37:1113-5. 2006
    ..We wished to confirm these findings using commercially available assays and to provide data to allow the design of intervention studies...
  39. doi Ten-years of the British Association of Stroke Physicians (BASP)
    Peter Langhorne
    Glasgow Royal Infirmary, Academic Section of Geriatric Medicine, Glasgow, UK
    Int J Stroke 5:484-5. 2010
    ..BASP members have been central to service improvements in recent years. Many challenges remain for stroke medicine in the United Kingdom but BASP is well placed to address these challenges...
  40. doi Elevated troponin after stroke: a systematic review
    Gillian Kerr
    Academic Section of Geriatric Medicine, Faculty of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Cerebrovasc Dis 28:220-6. 2009
    ..Troponin levels are elevated in some acute stroke patients, but the clinical significance of this is unclear...
  41. ncbi Interventions for improving sit-to-stand ability following stroke
    Alex Pollock
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Buchanan House, Cowcaddens Road, Glasgow, UK, G4 0BA
    Cochrane Database Syst Rev 5:CD007232. 2014
    ..Following stroke, patients can experience a number of problems relating to the ability to sit-to-stand independently...
  42. ncbi The impact of stroke nurse specialist input on risk factor modification: a randomised controlled trial
    Graham Ellis
    Academic Section of Geriatric Medicine, 3rd Floor, Centre Block, Glasgow Royal Infirmary, Glasgow G4 0SF, UK
    Age Ageing 34:389-92. 2005
  43. doi Sex differences in incidence, mortality, and survival in individuals with stroke in Scotland, 1986 to 2005
    James D Lewsey
    Public Health and Health Policy, University of Glasgow, Glasgow, UK
    Stroke 40:1038-43. 2009
    ..The aim of this study was to examine the effect of sex across different age groups and over time for stroke incidence, 30-day case-fatality, and mortality...
  44. ncbi Stroke units: the next 10 years
    Peter Langhorne
    Academic Section of Geriatric Medicine, Royal Infirmary, Glasgow G4 OSF, UK
    Lancet 363:834-5. 2004
  45. ncbi Therapy-based rehabilitation for stroke patients living at home
    Lynn Legg
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary, Glasgow University, UK
    Stroke 35:1022. 2004
  46. ncbi Impact and influences on caregiver outcomes at one year post-stroke
    Lorraine N Smith
    Nursing and Midwifery School, University of Glasgow, Glasgow G12 8LW, UK
    Cerebrovasc Dis 18:145-53. 2004
    ..Four outcome measures of carer stress and coping at one year post-stroke were identified: carer general health, anxiety, depression and perception of stress...
  47. ncbi Interventions for visual field defects in patients with stroke
    Alex Pollock
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Buchanan House, Cowcaddens Road, Glasgow, UK, G4 0BA
    Cochrane Database Syst Rev 10:CD008388. 2011
    ....
  48. ncbi Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study
    Olivia Wu
    Department of Obstetrics and Gynaecology, University of Glasgow, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, UK
    Thromb Haemost 94:17-25. 2005
    ..However, further studies are required to establish with greater confidence the associations of these, and other, thrombophilias with venous thromboembolism among hormone users...