Sarah L Allinson

Summary

Affiliation: Lancaster University
Country: UK

Publications

  1. doi request reprint DNA end-processing enzyme polynucleotide kinase as a potential target in the treatment of cancer
    Sarah L Allinson
    School of Health and Medicine, Division of Biomedical and Life Sciences, Lancaster University, Lancaster LA14YQ, UK
    Future Oncol 6:1031-42. 2010
  2. doi request reprint Cellular and sub-cellular responses to UVA in relation to carcinogenesis
    Andrew J Ridley
    Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, UK
    Int J Radiat Biol 85:177-95. 2009
  3. doi request reprint Cadmium and copper inhibit both DNA repair activities of polynucleotide kinase
    James R Whiteside
    Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster, UK
    DNA Repair (Amst) 9:83-9. 2010
  4. doi request reprint Timeframes of UVA-induced bystander effects in human keratinocytes
    James R Whiteside
    Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster, UK
    Photochem Photobiol 87:435-40. 2011
  5. pmc The phosphatase activity of mammalian polynucleotide kinase takes precedence over its kinase activity in repair of single strand breaks
    Caroline J Dobson
    Biomedical Sciences Unit, Department of Biological Sciences, Lancaster University, Lancaster, LA1 4YQ, UK
    Nucleic Acids Res 34:2230-7. 2006
  6. ncbi request reprint Growth kinetics in MCF-7 cells modulate benzo[a]pyrene-induced CYP1A1 up-regulation
    Haiyan Jiao
    Biomedical Sciences Unit, Department of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK
    Mutagenesis 22:111-6. 2007

Collaborators

  • David H Phillips
  • F L Martin
  • James R Whiteside
  • Trevor J McMillan
  • Andrew J Ridley
  • Haiyan Jiao
  • Caroline J Dobson
  • Clare L Box
  • Michael J Walsh
  • Kathy J Cole
  • Rebecca Hewitt

Detail Information

Publications6

  1. doi request reprint DNA end-processing enzyme polynucleotide kinase as a potential target in the treatment of cancer
    Sarah L Allinson
    School of Health and Medicine, Division of Biomedical and Life Sciences, Lancaster University, Lancaster LA14YQ, UK
    Future Oncol 6:1031-42. 2010
    ..Although still in the early stages of development, PNK inhibition represents a promising means of enhancing the efficacy of existing cancer treatments...
  2. doi request reprint Cellular and sub-cellular responses to UVA in relation to carcinogenesis
    Andrew J Ridley
    Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, UK
    Int J Radiat Biol 85:177-95. 2009
    ..The aim of this review is to consider the mechanisms that underlie UVA-induced cellular damage, how this damage may be prevented or repaired and the signal transduction processes that are elicited in response to it...
  3. doi request reprint Cadmium and copper inhibit both DNA repair activities of polynucleotide kinase
    James R Whiteside
    Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster, UK
    DNA Repair (Amst) 9:83-9. 2010
    ..The inhibition of PNK by environmentally and physiologically relevant concentrations of cadmium and copper suggests a novel means by which these toxic heavy metals may exert their carcinogenic and neurotoxic effects...
  4. doi request reprint Timeframes of UVA-induced bystander effects in human keratinocytes
    James R Whiteside
    Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster, UK
    Photochem Photobiol 87:435-40. 2011
    ..These data indicate that a single exposure to UVA can exert an effect for several days postirradiation, thus amplifying the deleterious effects of exposure...
  5. pmc The phosphatase activity of mammalian polynucleotide kinase takes precedence over its kinase activity in repair of single strand breaks
    Caroline J Dobson
    Biomedical Sciences Unit, Department of Biological Sciences, Lancaster University, Lancaster, LA1 4YQ, UK
    Nucleic Acids Res 34:2230-7. 2006
    ..PNK preferentially binds 3'-phosphorylated substrates and DNA binding to the phosphatase domain blocks further DNA binding by the kinase domain...
  6. ncbi request reprint Growth kinetics in MCF-7 cells modulate benzo[a]pyrene-induced CYP1A1 up-regulation
    Haiyan Jiao
    Biomedical Sciences Unit, Department of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK
    Mutagenesis 22:111-6. 2007
    ....