Research Topics
Species | N M PageSummaryAffiliation: Kingston University Country: UK Publications
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Detail Information
Publications
Characterization of the gene structures, precursor processing and pharmacology of the endokinin peptidesNigel M Page
School of Life Sciences, Kingston University, Penrhyn Road, Kingston upon Thames, Surrey KT1 2EE, London
Vascul Pharmacol 45:200-8. 2006..Particular consideration is also given to the potential interactions of the endokinins with the short NK(1) receptor isoform and to speculation of whether there could be an "endokinin-sensitive" NK(1) binding site...
Neurokinin B and pre-eclampsia: a decade of discoveryNigel M Page
School of Life Sciences, Kingston University London, Kingston upon Thames, Surrey, UK
Reprod Biol Endocrinol 8:4. 2010....
Differential mRNA splicing and precursor processing of neurokinin B in neuroendocrine tissuesNigel M Page
School of Life Sciences, Kingston University London, Penrhyn Road, Kingston upon Thames, Surrey, KT1 2EE, United Kingdom
Peptides 30:1508-13. 2009..Our results indicate that differential mRNA splicing and precursor processing is likely to play an important role in differentiating the actions of the tachykinin 3 gene products in both neuronal and endocrine tissues...
Gene regulation of neurokinin B and its receptor NK3 in late pregnancy and pre-eclampsiaN M Page
School of Life Sciences, Kingston University London, Penrhyn Road, Kingston upon Thames, Surrey, UK
Mol Hum Reprod 12:427-33. 2006..05). The present data suggest that the increased placental expression of TAC3 is part of the mechanism leading to the increased circulating levels of NKB in pre-eclampsia...
Immunochemical methods for the peptidomic analysis of tachykinin peptides and their precursorsNigel M Page
School of Life Sciences, Kingston University London, Kingston upon Thames, Surrey, UK
Methods Mol Biol 615:293-312. 2010..This chapter summarises some of the methods that have been developed in order to further purify and characterise individual groups of tachykinin peptides from the peptidome...
New challenges in the study of the mammalian tachykininsNigel M Page
School of Animal and Microbial Sciences, The University of Reading, Reading, RG6 6AJ, UK
Peptides 26:1356-68. 2005..This review addresses recent advances in this exciting field and raises challenging new concepts...
Tachykinins regulate the function of plateletsGwenda J Graham
School of Animal and Microbial Sciences, The University of Reading, Whiteknights, Reading, Berkshire, RG6 6AJ, UK
Blood 104:1058-65. 2004..Together our data implicate tachykinins, specifically SP and EKA/B, in the regulation of platelet function...
Placental peptides as markers of gestational diseaseNigel M Page
School of Animal and Microbial Sciences, The University of Reading, RG6 6AJ, UK
Reproduction 123:487-95. 2002..The importance of the new fields of genomics and proteomics in the future discovery of new peptide markers is illustrated...
Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterusEva Patak
Department of Anaesthesia, Royal Women's Hospital, Carlton, Victoria 3053, Australia
Biol Reprod 72:1125-33. 2005..The tachykinin NK3 receptor is expressed in considerable amounts only in uteri from nonpregnant diestrous animals, and its physiological significance remains to be clarified...
Regulation of the stimulant actions of neurokinin a and human hemokinin-1 on the human uterus: a comparison with histamineJocelyn N Pennefather
Department of Anaesthesia, Royal Women s Hospital, Carlton, Victoria 3053, Australia
Biol Reprod 75:334-41. 2006..The potencies of these peptides in tissues from nonpregnant women undergoing hysterectomy are consistent with their possible role in menstrual and menopausal disorders...
Characterization of the endokinins: human tachykinins with cardiovascular activityNigel M Page
School of Animal and Microbial Sciences, University of Reading, United Kingdom
Proc Natl Acad Sci U S A 100:6245-50. 2003..Thus, EKA/B could be the endocrineparacrine agonists at peripheral SP receptors and there may be as yet an unidentified receptor(s) for EKC/D...
The endocrinology of pre-eclampsiaNigel M Page
School of Animal and Microbial Sciences, The University of Reading, Reading RG6 6AJ, UK
Clin Endocrinol (Oxf) 57:413-23. 2002....
The human tachykinin NK1 (short form) and tachykinin NK4 receptor: a reappraisalNigel M Page
School of Animal and Microbial Sciences, The University of Reading, RG6 6AJ, Reading, UK
Eur J Pharmacol 437:27-30. 2002..We conclude that the proposed short form of the tachykinin NK1 receptor is a truncated genomic clone and that the human tachykinin NK4 receptor is in fact, the guinea pig tachykinin NK3 receptor...
