Zheng Liang Zhi
Affiliation: King's College London
- Polysaccharide multilayer nanoencapsulation of insulin-producing beta-cells grown as pseudoislets for potential cellular delivery of insulinZheng Liang Zhi
Metabolic Unit, King s College London School of Medicine, Guy s Hospital, London, United Kingdom
Biomacromolecules 11:610-6. 2010....
- Nano-scale encapsulation enhances allograft survival and function of islets transplanted in a mouse model of diabetesZ L Zhi
King s College London School of Medicine, London, UK
Diabetologia 55:1081-90. 2012..We aimed to test whether early islet loss can be limited and transplant survival improved by the application of conformal nano-coating layers to islets...
- Multilayer nanoencapsulation: a nanomedicine technology for diabetes research and managementZheng Liang Zhi
Diabetes Research Group, King s College London School of Medicine, Guy s Hospital, London SE1 1UL, UK
Diabetes Res Clin Pract 100:162-9. 2013..In early studies aimed at formulating an effective oral insulin preparation, insulin-chitosan colloids coated with nanolayers of chitosan and heparin had enhanced acid stability and effectively lowered blood glucose in an animal model...
- Fluorescence intensity- and lifetime-based glucose sensing using glucose/galactose-binding proteinJohn C Pickup
Diabetes Research Group, King s College London School of Medicine, Guy s Hospital, London, United Kingdom
J Diabetes Sci Technol 7:62-71. 2013..Measuring fluorescence lifetime rather than intensity has particular potential advantages for in vivo sensing. A prototype fiber-optic-based glucose sensor using this technology is being tested...
- Nanomedicine and its potential in diabetes research and practiceJohn C Pickup
Unit for Metabolic Medicine, King s College London School of Medicine, Guy s Hospital, London, UK
Diabetes Metab Res Rev 24:604-10. 2008..g. tissue complications) using quantum dots (QDs) or gold nanoparticles, and single-molecule detection for the study of molecular diversity in diabetes pathology...
- Improving cellular function and immune protection via layer-by-layer nanocoating of pancreatic islet β-cell spheroids cocultured with mesenchymal stem cellsTasneem Bhaiji
Diabetes Research Group, King s College London School of Medicine, Guy s Hospital, London SE1 1UL, United Kingdom
J Biomed Mater Res A 100:1628-36. 2012..This strategy of nanoencapsulating islet cocultures appears promising to improve cellular delivery of insulin for treating type 1 diabetes...
- Multilayered nanocoatings incorporating superparamagnetic nanoparticles for tracking of pancreatic islet transplants with magnetic resonance imagingYang Wang
Diabetes Research Group, King s College London School of Medicine, Guy s Hospital Campus, London SE1 1UL, UK
Chem Commun (Camb) 49:7255-7. 2013....