Research Topics
| Yoh ZenSummaryAffiliation: King's College London Country: UK Publications
| Collaborators
|
Detail Information
Publications
IgG4-related lung and pleural disease: a clinicopathologic study of 21 casesYoh Zen
Institute of Liver Studies, King s College Hospital, London, UK
Am J Surg Pathol 33:1886-93. 2009..In conclusion, IgG4-related diseases show a greater variety of pulmonary and pleural lesions than previously thought. It is important, therefore, to know the morphologic variety and clinicopathologic characteristics of this disorder...- Sclerosing cholangitis with granulocytic epithelial lesion: a benign form of sclerosing cholangiopathyYoh Zen
Institute of Liver Studies, GI and Nutrition Centre, King s College London School of Medicine at King s College Hospital, London, UK
Am J Surg Pathol 36:1555-61. 2012..Although rare, the diagnosis of sclerosing cholangitis with GEL is important in view of its excellent and apparently sustained response to immunosuppressive treatment... - Retroperitoneal and aortic manifestations of immunoglobulin G4-related diseaseYoh Zen
Histopathology Section, Institute of Liver Studies, King s College Hospital, Denmark Hill, London, UK
Semin Diagn Pathol 29:212-8. 2012..The risk of rupture appears to be low in patients with IgG4-related aortic aneurysms, but immunosuppressive therapy may trigger this critical complication by reducing the wall thickness... - Immunoglobulin G4-related sclerosing cholangitis: pathologic features and histologic mimicsYoh Zen
Histopathology Section, Institute of Liver Studies, King s College Hospital, Denmark Hill, London, UK
Semin Diagn Pathol 29:205-11. 2012..Histologic mimics of IgG4-related sclerosing cholangitis include primary sclerosing cholangitis, follicular cholangitis, and sclerosing cholangitis with granulocytic epithelial lesion, the latter 2 being recently described entities... - Intraductal tubulopapillary neoplasm of the bile duct: potential origin from peribiliary cystsYoh Zen
Institute of Liver Studies, King s College Hospital, London SE5 9RS, UK
Hum Pathol 43:440-5. 2012..These pathological and genetic features are similar to those of pancreatic ITPNs. This report suggested that ITPNs may rarely develop in the bile duct seemingly in association with peribiliary cysts... - Follicular cholangitis and pancreatitis - clinicopathological features and differential diagnosis of an under-recognized entityYoh Zen
Institute of Liver Studies, King s College Hospital, London, UK
Histopathology 60:261-9. 2012..Here in we describe an unusual pancreatocholangitis whose features suggest a distinct disease entity... - Two distinct pathways of carcinogenesis in primary sclerosing cholangitisYoh Zen
Institute of Liver Studies, King s College Hospital, London, UK
Histopathology 59:1100-10. 2011..To identify clinicopathological characteristics of cholangiocarcinoma and premalignant lesions arising in patients with primary sclerosing cholangitis (PSC)... 
Type 1 autoimmune pancreatitisYoh Zen
Institute of Liver Studies, King s College Hospital and King s College London School of Medicine, Denmark Hill, London SE5 9RS, UK
Orphanet J Rare Dis 6:82. 2011..However, the exact role of IgG4 in this disease still remains to be clarified. It seems important to recognize this unique entity given that the disease is treatable with steroids...- Mucinous cystic neoplasms of the liver: a clinicopathological study and comparison with intraductal papillary neoplasms of the bile ductYoh Zen
Institute of Liver Studies, King s College Hospital, London, UK
Mod Pathol 24:1079-89. 2011.... - Intestinal phenotypes in pediatric gallbladder epitheliumYoh Zen
Institute of Liver Studies, King s College Hospital, SE5 9RS London, United Kingdom
Hum Pathol 42:1454-8. 2011..Intestinal metaplasia, as associated with cholangiopathy or carcinogenesis in adult patients, may represent an immature phenotype of biliary epithelium... - Hepatic pseudolymphoma: a clinicopathological study of five cases and review of the literatureYoh Zen
Institute of Liver Studies, King s College Hospital, London SE5 9RS, UK
Mod Pathol 23:244-50. 2010..The diagnosis of hepatic pseudolymphoma can be challenging especially with biopsied specimens, but could be aided by a characteristic growth pattern, in situ hybridization, analyses of gene rearrangements, or a follow-up based on images... 
Retroperitoneal fibrosis: a clinicopathologic study with respect to immunoglobulin G4Yoh Zen
Institute of Liver Studies, King s College Hospital, Denmark Hill, London SE5 9RS, UK
Am J Surg Pathol 33:1833-9. 2009..This distinction seems important to help better characterize the biology/pathogenesis of both groups and better predict the possibility of other IgG4-related processes at other anatomic sites...- Immunoglobulin G4-positive plasma cell infiltration in explanted livers for primary sclerosing cholangitisYoh Zen
Institute of Liver Studies, King s College Hospital, London, UK
Histopathology 58:414-22. 2011..To explore whether immunoglobulin (Ig)G4-related sclerosing cholangitis (IgG4-SC) contributes to end-stage primary sclerosing cholangitis (PSC) in the United Kingdom... - Pathogenesis of IgG4-related diseaseYoh Zen
Institute of Liver Studies, King s College Hospital, London, UK
Curr Opin Rheumatol 23:114-8. 2011..To review studies that have examined underlying genetic and immunological aspects of IgG4-related disease... - Cholangiocarcinoma complicating recurrent primary sclerosing cholangitis after liver transplantationShirin E Khorsandi
Liver Institute, King s College Hospital, Denmark Hill, London, UK
Transpl Int 24:e93-6. 2011..This case report reviews the literature and highlights the need to consider cholangiocarcinoma in transplanted patients with PSC that clinically/biochemically deteriorate... - Inflammatory disease of the bile ducts-cholangiopathies: liver biopsy challenge and clinicopathological correlationBernard Portmann
Institute of Liver Studies, King s College Hospital, London, UK
Histopathology 60:236-48. 2012..The review stresses the importance of evaluating histological changes in conjunction with clinical information... - Mixed phenotype hepatocellular carcinoma after transarterial chemoembolization and liver transplantationChikako Zen
Institute of Liver Studies, King s College Hospital, London, United Kingdom
Liver Transpl 17:943-54. 2011..Further studies are needed to investigate the potential relationships between TACE and HCC subpopulations with a chemoembolization-resistant phenotype and their clinical significance... - Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis?Daniel Smyk
Institute of Liver Studies and Liver Unit, King s College London School of Medicine at King s College Hospital and Kings College Hospital NHS Trust Foundation Trust, London, United Kingdom
World J Gastroenterol 18:4855-65. 2012..The view that mycobacteria are infectious triggers of PBC is intriguing, but the data provided so far are not conclusive... - IgG4-related disease: a cross-sectional study of 114 casesYoh Zen
Institute of Liver Studies, King s College Hospital, London, UK
Am J Surg Pathol 34:1812-9. 2010..Further study is necessary to conclude whether these features reflect different manifestations of a single disease entity or suggest different underlying etiologic factors... - Early predictors of corticosteroid treatment failure in icteric presentations of autoimmune hepatitisAndrew D Yeoman
Institute of Liver Studies, Kings College Hospital NHS Trust Foundation Trust, Denmark Hill, London, UK
Hepatology 53:926-34. 2011..Treatment failure is best predicted by change in MELD-Na and UKELD at day 7. Early identification of nonresponders may allow timely escalation of immunosuppression to prevent clinical deterioration... - Metastatic pulmonary adenocarcinoma 6 years after curative resection for ampullary adenocarcinoma. Metastatic disease from initial primary or metachronous tumour?Alexandros Giakoustidis
Institute of Liver Studies, King s College Hospital, London, United Kingdom
JOP 12:32-6. 2011..With patients surviving longer after pancreatic resection, the challenges now is the management of the unresolved longer-term issues... - Portal blood supply to locally progressed hepatocellular carcinoma after transcatheter arterial chemoembolization: Observation on CT during arterial portographyShiro Miyayama
Departments of Diagnostic Radiology Pathology, Fukuiken Saiseikai Hospital, Funabashi, Wadanaka cho, Fukui Department of Radiology, Kanazawa University Graduate School of Medical Science, Takara machi, Kanazawa, Japan Institute of Liver Studies, Kings College Hospital, Denmark Hill, London, UK
Hepatol Res 41:853-66. 2011..Conclusions: PB supply to locally progressed tumor after TACE became apparent on CTAP. Arterial damage by TACE, incomplete TACE, and preexisting tumor tissues supplied by PB may be the main causes... - IgG4 CholangiopathyYoh Zen
Institute of Liver Studies, King s College Hospital, Denmark Hill, London SE5 9RS, UK
Int J Hepatol 2012:472376. 2012..It is still unknown why IgG4 levels are specifically elevated in patients with this disease. IgG4 might be secondarily overexpressed by Th2 or regulatory cytokines given the lack of evidence that IgG4 is an autoantibody...