Yoh Zen

Summary

Affiliation: King's College London
Country: UK

Publications

  1. doi request reprint IgG4-related lung and pleural disease: a clinicopathologic study of 21 cases
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Am J Surg Pathol 33:1886-93. 2009
  2. pmc IgG4 Cholangiopathy
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Int J Hepatol 2012:472376. 2012
  3. doi request reprint Possible involvement of CCL1-CCR8 interaction in lymphocytic recruitment in IgG4-related sclerosing cholangitis
    Yoh Zen
    Institute of Liver Studies, King s College London at King s College Hospital, London, UK Electronic address
    J Hepatol 59:1059-64. 2013
  4. doi request reprint Sclerosing cholangitis with granulocytic epithelial lesion: a benign form of sclerosing cholangiopathy
    Yoh Zen
    Institute of Liver Studies, GI and Nutrition Centre, King s College London School of Medicine at King s College Hospital, London, UK
    Am J Surg Pathol 36:1555-61. 2012
  5. doi request reprint Retroperitoneal and aortic manifestations of immunoglobulin G4-related disease
    Yoh Zen
    Histopathology Section, Institute of Liver Studies, King s College Hospital, Denmark Hill, London, UK
    Semin Diagn Pathol 29:212-8. 2012
  6. doi request reprint Immunoglobulin G4-related sclerosing cholangitis: pathologic features and histologic mimics
    Yoh Zen
    Histopathology Section, Institute of Liver Studies, King s College Hospital, Denmark Hill, London, UK
    Semin Diagn Pathol 29:205-11. 2012
  7. doi request reprint Intraductal tubulopapillary neoplasm of the bile duct: potential origin from peribiliary cysts
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London SE5 9RS, UK
    Hum Pathol 43:440-5. 2012
  8. doi request reprint Follicular cholangitis and pancreatitis - clinicopathological features and differential diagnosis of an under-recognized entity
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Histopathology 60:261-9. 2012
  9. doi request reprint Two distinct pathways of carcinogenesis in primary sclerosing cholangitis
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Histopathology 59:1100-10. 2011
  10. pmc Type 1 autoimmune pancreatitis
    Yoh Zen
    Institute of Liver Studies, King s College Hospital and King s College London School of Medicine, Denmark Hill, London SE5 9RS, UK
    Orphanet J Rare Dis 6:82. 2011

Collaborators

Detail Information

Publications27

  1. doi request reprint IgG4-related lung and pleural disease: a clinicopathologic study of 21 cases
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Am J Surg Pathol 33:1886-93. 2009
    ..In conclusion, IgG4-related diseases show a greater variety of pulmonary and pleural lesions than previously thought. It is important, therefore, to know the morphologic variety and clinicopathologic characteristics of this disorder...
  2. pmc IgG4 Cholangiopathy
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Int J Hepatol 2012:472376. 2012
    ..It is still unknown why IgG4 levels are specifically elevated in patients with this disease. IgG4 might be secondarily overexpressed by Th2 or regulatory cytokines given the lack of evidence that IgG4 is an autoantibody...
  3. doi request reprint Possible involvement of CCL1-CCR8 interaction in lymphocytic recruitment in IgG4-related sclerosing cholangitis
    Yoh Zen
    Institute of Liver Studies, King s College London at King s College Hospital, London, UK Electronic address
    J Hepatol 59:1059-64. 2013
    ..This study was conducted to address which chemotactic factors are involved in this condition...
  4. doi request reprint Sclerosing cholangitis with granulocytic epithelial lesion: a benign form of sclerosing cholangiopathy
    Yoh Zen
    Institute of Liver Studies, GI and Nutrition Centre, King s College London School of Medicine at King s College Hospital, London, UK
    Am J Surg Pathol 36:1555-61. 2012
    ..Although rare, the diagnosis of sclerosing cholangitis with GEL is important in view of its excellent and apparently sustained response to immunosuppressive treatment...
  5. doi request reprint Retroperitoneal and aortic manifestations of immunoglobulin G4-related disease
    Yoh Zen
    Histopathology Section, Institute of Liver Studies, King s College Hospital, Denmark Hill, London, UK
    Semin Diagn Pathol 29:212-8. 2012
    ..The risk of rupture appears to be low in patients with IgG4-related aortic aneurysms, but immunosuppressive therapy may trigger this critical complication by reducing the wall thickness...
  6. doi request reprint Immunoglobulin G4-related sclerosing cholangitis: pathologic features and histologic mimics
    Yoh Zen
    Histopathology Section, Institute of Liver Studies, King s College Hospital, Denmark Hill, London, UK
    Semin Diagn Pathol 29:205-11. 2012
    ..Histologic mimics of IgG4-related sclerosing cholangitis include primary sclerosing cholangitis, follicular cholangitis, and sclerosing cholangitis with granulocytic epithelial lesion, the latter 2 being recently described entities...
  7. doi request reprint Intraductal tubulopapillary neoplasm of the bile duct: potential origin from peribiliary cysts
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London SE5 9RS, UK
    Hum Pathol 43:440-5. 2012
    ..These pathological and genetic features are similar to those of pancreatic ITPNs. This report suggested that ITPNs may rarely develop in the bile duct seemingly in association with peribiliary cysts...
  8. doi request reprint Follicular cholangitis and pancreatitis - clinicopathological features and differential diagnosis of an under-recognized entity
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Histopathology 60:261-9. 2012
    ..Here in we describe an unusual pancreatocholangitis whose features suggest a distinct disease entity...
  9. doi request reprint Two distinct pathways of carcinogenesis in primary sclerosing cholangitis
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Histopathology 59:1100-10. 2011
    ..To identify clinicopathological characteristics of cholangiocarcinoma and premalignant lesions arising in patients with primary sclerosing cholangitis (PSC)...
  10. pmc Type 1 autoimmune pancreatitis
    Yoh Zen
    Institute of Liver Studies, King s College Hospital and King s College London School of Medicine, Denmark Hill, London SE5 9RS, UK
    Orphanet J Rare Dis 6:82. 2011
    ..However, the exact role of IgG4 in this disease still remains to be clarified. It seems important to recognize this unique entity given that the disease is treatable with steroids...
  11. doi request reprint Mucinous cystic neoplasms of the liver: a clinicopathological study and comparison with intraductal papillary neoplasms of the bile duct
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Mod Pathol 24:1079-89. 2011
    ....
  12. doi request reprint Intestinal phenotypes in pediatric gallbladder epithelium
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, SE5 9RS London, United Kingdom
    Hum Pathol 42:1454-8. 2011
    ..Intestinal metaplasia, as associated with cholangiopathy or carcinogenesis in adult patients, may represent an immature phenotype of biliary epithelium...
  13. doi request reprint Hepatic pseudolymphoma: a clinicopathological study of five cases and review of the literature
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London SE5 9RS, UK
    Mod Pathol 23:244-50. 2010
    ..The diagnosis of hepatic pseudolymphoma can be challenging especially with biopsied specimens, but could be aided by a characteristic growth pattern, in situ hybridization, analyses of gene rearrangements, or a follow-up based on images...
  14. doi request reprint Immunoglobulin G4-positive plasma cell infiltration in explanted livers for primary sclerosing cholangitis
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Histopathology 58:414-22. 2011
    ..To explore whether immunoglobulin (Ig)G4-related sclerosing cholangitis (IgG4-SC) contributes to end-stage primary sclerosing cholangitis (PSC) in the United Kingdom...
  15. ncbi request reprint Retroperitoneal fibrosis: a clinicopathologic study with respect to immunoglobulin G4
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Am J Surg Pathol 33:1833-9. 2009
    ..This distinction seems important to help better characterize the biology/pathogenesis of both groups and better predict the possibility of other IgG4-related processes at other anatomic sites...
  16. doi request reprint Pathogenesis of IgG4-related disease
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Curr Opin Rheumatol 23:114-8. 2011
    ..To review studies that have examined underlying genetic and immunological aspects of IgG4-related disease...
  17. ncbi request reprint Liver transplantation and autoimmune liver diseases
    Rodrigo Liberal
    Institute of Liver Studies, King s College London School of Medicine at King s College Hospital, London, United Kingdom Faculty of Medicine, University of Porto, Porto, Portugal
    Liver Transpl 19:1065-77. 2013
    ....
  18. doi request reprint Cholangiocarcinoma complicating recurrent primary sclerosing cholangitis after liver transplantation
    Shirin E Khorsandi
    Liver Institute, King s College Hospital, Denmark Hill, London, UK
    Transpl Int 24:e93-6. 2011
    ..This case report reviews the literature and highlights the need to consider cholangiocarcinoma in transplanted patients with PSC that clinically/biochemically deteriorate...
  19. doi request reprint Inflammatory disease of the bile ducts-cholangiopathies: liver biopsy challenge and clinicopathological correlation
    Bernard Portmann
    Institute of Liver Studies, King s College Hospital, London, UK
    Histopathology 60:236-48. 2012
    ..The review stresses the importance of evaluating histological changes in conjunction with clinical information...
  20. doi request reprint Mixed phenotype hepatocellular carcinoma after transarterial chemoembolization and liver transplantation
    Chikako Zen
    Institute of Liver Studies, King s College Hospital, London, United Kingdom
    Liver Transpl 17:943-54. 2011
    ..Further studies are needed to investigate the potential relationships between TACE and HCC subpopulations with a chemoembolization-resistant phenotype and their clinical significance...
  21. ncbi request reprint Elevated Ki-67 labeling index in 'synchronous liver metastases' of well differentiated enteropancreatic neuroendocrine tumor
    Yoh Zen
    Histopathology Section, King s College London School of Medicine at King s College Hospital, London, UK
    Pathol Int 63:532-8. 2013
    ..In conclusion, synchronous liver metastases can yield a higher Ki-67 labeling index than primary neuroendocrine tumours, particularly when the secondary is greater than 40 mm. ..
  22. pmc Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis?
    Daniel Smyk
    Institute of Liver Studies and Liver Unit, King s College London School of Medicine at King s College Hospital and Kings College Hospital NHS Trust Foundation Trust, London, United Kingdom
    World J Gastroenterol 18:4855-65. 2012
    ..The view that mycobacteria are infectious triggers of PBC is intriguing, but the data provided so far are not conclusive...
  23. doi request reprint IgG4-related disease: a cross-sectional study of 114 cases
    Yoh Zen
    Institute of Liver Studies, King s College Hospital, London, UK
    Am J Surg Pathol 34:1812-9. 2010
    ..Further study is necessary to conclude whether these features reflect different manifestations of a single disease entity or suggest different underlying etiologic factors...
  24. doi request reprint Early predictors of corticosteroid treatment failure in icteric presentations of autoimmune hepatitis
    Andrew D Yeoman
    Institute of Liver Studies, Kings College Hospital NHS Trust Foundation Trust, Denmark Hill, London, UK
    Hepatology 53:926-34. 2011
    ..In total, four patients died in the treatment failure group compared with one in the responder group (4/13 = 31% versus 1/59 = 1.7%, P = 0.003)...
  25. ncbi request reprint Metastatic pulmonary adenocarcinoma 6 years after curative resection for ampullary adenocarcinoma. Metastatic disease from initial primary or metachronous tumour?
    Alexandros Giakoustidis
    Institute of Liver Studies, King s College Hospital, London, United Kingdom
    JOP 12:32-6. 2011
    ..With patients surviving longer after pancreatic resection, the challenges now is the management of the unresolved longer-term issues...
  26. doi request reprint Portal blood supply to locally progressed hepatocellular carcinoma after transcatheter arterial chemoembolization: Observation on CT during arterial portography
    Shiro Miyayama
    Departments of Diagnostic Radiology Pathology, Fukuiken Saiseikai Hospital, Funabashi, Wadanaka cho, Fukui Department of Radiology, Kanazawa University Graduate School of Medical Science, Takara machi, Kanazawa, Japan Institute of Liver Studies, Kings College Hospital, Denmark Hill, London, UK
    Hepatol Res 41:853-66. 2011
    ..Conclusions:  PB supply to locally progressed tumor after TACE became apparent on CTAP. Arterial damage by TACE, incomplete TACE, and preexisting tumor tissues supplied by PB may be the main causes...
  27. doi request reprint Childhood hepatocellular carcinoma: a clinicopathological study of 12 cases with special reference to EpCAM
    Yoh Zen
    Histopathology Section, Institute of Liver Studies, King s College Hospital, London, UK
    Histopathology 64:671-82. 2014
    ..To elucidate the characteristics of hepatocellular carcinoma (HCC) in children...